20,277 Works

Homicide rates in Brazilian state of Amapá: comparison among four periods: 1982-1990, 1991-1999, 2000-2008, and 2009-2017

Ana Carolina Raimondi & Antonio Marcos Raimondi
The aim of this study is comparing the homicide rates of Brazilian State of Amapá, among four different periods: 1982-1990, 1991-1999, 2000-2008, and 2009-2017 . One-factor ANOVA procedure was employed to study the effect of levels (periods) on AHR. After ANOVA, a Tukey’s test (a≤0.05) was employed to comparing pairs of means by period. Conclusion: There was a significative increase in annual homicide rates over time, during the period 1982- 2017, in Amapá State, Brazil.

DAISY: A tool to document biomedical research data processing for accountability under the GDPR

Pinar Alper, Regina Becker, Valentin Grouès, Sandrine Munoz, Yohan Jarosz, Jacek Lebioda, Kavita Rege, Christophe Trefois, Venkata Satagopam & Reinhard Schneider
The General Data Protection Regulation (GDPR) brings the principles of "responsibility" and "accountability", which necessitates the documentation of any processing of personal data, including data used for research. If your work involves bio-samples and data from living Human Subjects, a.k.a.Human Data, then you fall under the GDPR data documentation requirement.
Data Information System (DAISY) isan open-source a software tool to support the GDPR-compliant documentation of data. DAISY is being developed and used at the Luxembourg Centre...

Raw data for all module trial results.

Zana Majeed, Felicitas Koch, Joshua Morgan, Heidi Anderson, Jennifer Wilson & Robin L. Cooper
Sigma Plot version 13 files for Figures 4, 6-8, 10-12, 14-16.

Subset analysis of the safety and efficacy of nivolumab in elderly patients with metastatic melanoma

Morganna Freeman, Youngchul Kim & Jeffrey Weber
Cancer immunotherapy has generated significant response rates and prolonged survival, particularly in melanoma, where sustained clinical responses can be seen even after cessation of therapy. Inhibition of critical immune checkpoints, while clinically effective, also carry the risk of immune-related adverse events (irAEs) which have been well-described in the literature [Topalian 2012]. The treatment of elderly patients with checkpoint inhibition presents a unique challenge, as nearly half of all malignancies are diagnosed in patients >65 [Jemal...

Deep PolyOmics: Towards an Integrative Blood+MRI+Omics AI Model for Early Detection and Diagnosis of Prostate Cancers

Sriganesh Srihari, Lewis Smith, Ray Kwong & Elliot Smith
When detected early, PCa patients have >90% chance of >5-year survival compared to just 25% when detected late. PSA screening alone cannot accurately estimate the presence of clinically significant (Gleason grade≥4+3; CS) cancers, whereas confirmatory biopsies are invasive, painful and present sepsis risk.

Early (prebiopsy) and accurate diagnosis of CS cancers by combining prebiopsy prostate MRI with ‘liquid biopsies’.

We are developing a ‘PolyOmics’ machine-learning model that integrates age, race, family history, PSA measurements, prostate mpMRI T2+DWI...

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