3,349 Works

A digital nanoscope for the genome

David Eccles, Jodie Chandler, Mali Camberis, Graham Le Gros & Jonathan Ewbank
Nippostrongylus brasiliensis (Nippo) is a small blood-feeding rodent parasite that is an extremely useful model for the study of human hookworm infection, particularly in regards to the induced immune response.

The current reference genome for this parasite is broken into tens of thousands of pieces with minimal annotation. Despite the small(ish) size of the eukaryotic genome of Nippo, it has a complex repetitive structure that is impossible to correctly assembly using only short reads. When this...

Health systems strengthening via surveillance in a rural district of Sierra Leone: ensuring lessons learned from Ebola are not lost

Antonio Isidro Carrion Martin, Yassin Jalloh, Parastou Sara Valeh, Donald Sonne Kazungu, Augustine Jimmisa, Suleiman Jr. Tejan, Mohammed O. Sanko, Kassim Kamara, Alphonso Sanko, Anthony Omoko, Robert N. Musoke, Sibylle Sang, Idriss Ait-Bouziad & Grazia Caleo
This abstract corresponds with the following slides: https://f1000research.com/slides/6-701, presented at Médecins Sans Frontières UK Scientific Days: Innovation 2017. To watch the presentation click here: https://f1000research.com/videos/6-818.

This abstract is part of an F1000Research gateway that includes posters, slides and videos from the MSF Scientific Day: Innovation 2017. To see more please visit: https://f1000research.com/gateways/MSF/innovation.

Efficacy of a low-cost, heat-stable oral rotavirus vaccine in Niger: a randomised, controlled trial

Amadou Matar Seck, Sheila Isanaka, Ousmane Guindo, Celine Langendorf, Brian D Plikaytis, Nathan Sayinzoga-Makombe, Monica Malone McNeal, Nicole Meyer, Eric Adehossi, Ali Djibo, Maya Shah, Bruno Jochum & Rebecca F Grais
This presentation reviews the results of a randomised, controlled trial designed to test the efficacy of a low-cost and heat-stable oral rotavirus vaccine in Niger.


Hugues Gentillon, Ludomir Stefańczyk, Michał Strzelecki & Maria Respondek-Liberska
ABNORMAL was defined as ROIs with different tissue - e.g. white matter in the temporal region vs grey matter in the cerebral hemispheres of the brain.

Hypoxic and hyperoxic preconditioning in organ protection against ischemia-reperfusion injury: experimental study

Irina A. Mandel, Sergey L. Mikheev, Yuriy K. Podoxenov, Irina V. Suhodolo, Andrey Yu. Podoxenov, Yulia S. Svirko, Andrey S. Sementsov, Leonid N. Maslov & Vladimir M. Shipulin

Raw data supporting the findings in this study.

Gerhard J. Molderings, Thomas Zienkiewicz, Jürgen Homann, Markus Menzen & Lawrence B. Afrin
Sheet 1, Data for the German patient cohort; Sheet 2, Data for the U.S. patient cohort.

Contrast sensitivity indicates processing level of visual illusions

Bruno G. Breitmeyer, James M. Brown, Ralph G. Hale & Richard W. Plummer
While the striate cortical contrast-response function is nearly linear, the extrastriate function shows a steep, nonlinear increase for contrasts ranging from 0.0 to 0.30 and a gradual increase toward response saturation for higher contrasts. The extrastriate response comports with: 1) the tendency for neural activity in the ventral cortical pathway to shift from stimulus-, energy-dependent coding at low cortical levels to percept-, information-dependent coding at higher levels; 2) the majority (≈70%) of local contrasts in...

Raw data corresponding to the results shown in Figure 1.

Jashdeep Bhattacharjee, Barun Das, Alaknanda Mishra, Preeti Sahay & Pramod Upadhyay

dnaasm – new tool to assemble repetitive DNA regions

Wiktor Kuśmirek & Robert Nowak
Some parts of the genome are composed of repetitive DNA sequences. Existing genome assemblers reconstruct these repetitive regions using information about the insert size length of paired-end tags.

We propose a modification of the algorithm for DNA de-novo assembly, which uses the relative frequency of reads to properly reconstruct repetitive sequences (tandem repeats). The main advantage of our approach is that tandem repeats, which are longer than the insert size of paired-end tags, can also be...

Access to non-communicable disease health care among non-camp Syrian refugees in northern Jordan

Manuela Rehr, Muhammad Shoaib, Idriss Ait-Bouziad, Cono Ariti, Paul Van Den Bosch, Sara Ellithy, Suhib Okour, Anais Deprade, Mohammad Altarawneh, Abdel Alshafee, Sadeq Gabashneh & Annick Lenglet
This abstract corresponds with the following slides: https://f1000research.com/slides/6-716, presented at Médecins Sans Frontières UK Scientific Days: Medical Research 2017. To watch the presentation click here: https://f1000research.com/videos/6-841.

This abstract is part of an F1000Research gateway that includes posters, slides and videos from the MSF Scientific Day: Medical Research 2017. To see more please visit: https://f1000research.com/gateways/MSF/scidays

The wheat data interoperability guidelines: feedback, news and next steps

Esther Dzale Yeumo
The wheat data interoperability guidelines (http://ist.blogs.inra.fr/wdi/) result from a joint effort of the wheat research community and data experts, who wish to make their research data more accessible, interoperable and reusable. During more than 18 months, the Wheat Data Interoperability working group questioned the wheat research community about their usage of data standards, discussed and selected a set of recommendations based on some consensual criterias.

This presentation will give you some feedback about the work of...

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