654,834 Works

In vitro evaluation of aerosol delivery of aztreonam lysine (azli): an adult mechanical ventilation model

A. Rodríguez, M. Cabrera, LF. Reyes, M. Bodí, S. Trefler, L. Canadell, D. Barahona, S. Ehrmann, I. Martin-Loeches, MI. Restrepo & L. Vecellio
Background: The delivery profile of Aztreonam lysine (AZLI) during mechanical ventilation (MV) is unknown. We evaluated the amount of AZLI drug delivered using an in vitro model of adult MV. Methods: An adult lung model designed to mimic current clinical practice was used. Both nebulizers were placed before a Y-piece and 4 settings were tested: A) Aeroneb solo® [AS] with a t-piece; B) AS with the spacer; C) M-Neb® [MN] with a t-piece and D)...

In vitro evaluation of aerosol delivery of aztreonam lysine (azli): an adult mechanical ventilation model

A. Rodríguez, M. Cabrera, LF. Reyes, M. Bodí, S. Trefler, L. Canadell, D. Barahona, S. Ehrmann, I. Martin-Loeches, MI. Restrepo & L. Vecellio
Background: The delivery profile of Aztreonam lysine (AZLI) during mechanical ventilation (MV) is unknown. We evaluated the amount of AZLI drug delivered using an in vitro model of adult MV. Methods: An adult lung model designed to mimic current clinical practice was used. Both nebulizers were placed before a Y-piece and 4 settings were tested: A) Aeroneb solo® [AS] with a t-piece; B) AS with the spacer; C) M-Neb® [MN] with a t-piece and D)...

Model - Fine Image Selector

Seung Seog Han
Requirements- BVLC PyCaffe

Download- Model Fine image selector :

How to useResNet-152; 6 outputs
#0 nail
#1 non-focused or tilted nail
#2 skin photo, not nail
#3 skin photo, not nail
#4 index photo, or EMR screenshot
#5 non-skin photo, general internet images

Model - Fine Image Selector

Seung Seog Han
Requirements- BVLC PyCaffe

Download- Model Fine image selector :

How to useResNet-152; 6 outputs
#0 nail
#1 non-focused or tilted nail
#2 skin photo, not nail
#3 skin photo, not nail
#4 index photo, or EMR screenshot
#5 non-skin photo, general internet images

The Role of Savings and Credit in Coping with Idiosyncratic Household Shocks

Stephen B. DeLoach & Marquessa Smith-Lin
This study examines the effect of access to formal banking services on households’ ability to smooth consumption in response to illness of adult workers. The institutional peculiarities of Indonesia’s largest commercial bank are exploited to separately estimate the effects of access to formal credit from savings. The means by which households smooth consumption differs depending on their access to formal services. Those with access to formal credit increase borrowing from banks, while those with access...

The Role of Savings and Credit in Coping with Idiosyncratic Household Shocks

Stephen B. DeLoach & Marquessa Smith-Lin
This study examines the effect of access to formal banking services on households’ ability to smooth consumption in response to illness of adult workers. The institutional peculiarities of Indonesia’s largest commercial bank are exploited to separately estimate the effects of access to formal credit from savings. The means by which households smooth consumption differs depending on their access to formal services. Those with access to formal credit increase borrowing from banks, while those with access...

Design, construction, and in vivo feasibility of a positioning device for irradiation of mice brains using a clinical linear accelerator and intensity modulated radiation therapy

Nicholas J. Rancilio, Shaun Dahl, Ilektra Athanasiadi & Carlos J. Perez-Torres
Purpose: The goal of this study was to design a positioning device that would allow for selective irradiation of the mouse brain with a clinical linear accelerator. Methods: We designed and fabricated an immobilization fixture that incorporates three functions: head stabilizer (through ear bars and tooth bar), gaseous anesthesia delivery and scavenging, and tissue mimic/bolus. Cohorts of five mice were irradiated such that each mouse in the cohort received a unique dose between 1000 and...

Enhanced vitamin B12 production in an innovative lupin tempeh is due to synergic effects of Rhizopus and Propionibacterium in cofermentation

Camilla Signorini, Aristodemo Carpen, Luigi Coletto, Gigliola Borgonovo, Elisabetta Galanti, Jessica Capraro, Chiara Magni, Ambra Abate, Stuart K. Johnson, Marcello Duranti & Alessio Scarafoni
Fermentation represents a valuable and cost-effective approach for food stabilisation and nutritional improvement. Tempeh is an example of soybean solid-state fermentation. In this work, we investigated the possibility of producing a tempeh analogue containing high amounts of vitamin B12 using seeds of three different species of the legume lupin, namely Lupinus albus, L. angustifolius and L. mutabilis, with Rhizopus oligosporus and Propionibacterium freudenreichii cofermentation. Synergic effects of Rhizopus and Propionibacterium in increasing vitamin B12 up...

Enhanced vitamin B12 production in an innovative lupin tempeh is due to synergic effects of Rhizopus and Propionibacterium in cofermentation

Camilla Signorini, Aristodemo Carpen, Luigi Coletto, Gigliola Borgonovo, Elisabetta Galanti, Jessica Capraro, Chiara Magni, Ambra Abate, Stuart K. Johnson, Marcello Duranti & Alessio Scarafoni
Fermentation represents a valuable and cost-effective approach for food stabilisation and nutritional improvement. Tempeh is an example of soybean solid-state fermentation. In this work, we investigated the possibility of producing a tempeh analogue containing high amounts of vitamin B12 using seeds of three different species of the legume lupin, namely Lupinus albus, L. angustifolius and L. mutabilis, with Rhizopus oligosporus and Propionibacterium freudenreichii cofermentation. Synergic effects of Rhizopus and Propionibacterium in increasing vitamin B12 up...

GRID

Data-Science Digital-Science
This collection contains all of the GRID releases.

Construction of nanostructured DNA harbouring phosphorodiamidate morpholino oligonucleotide for controlled tissue distribution in mice

Yosuke Takahashi, Yuki Araie, Daiki Nomura, Yuki Takahashi, Kohei Sano, Hideo Saji, Yoshinobu Takakura & Makiya Nishikawa
Phosphorodiamidate morpholino oligonucleotides (PMOs) are a class of antisense oligonucleotides used in the treatment of neuromuscular diseases. Their major drawbacks are high blood clearance and poor cellular delivery. Previously, we demonstrated that tripod-like nanostructured DNA, or tripodna, was efficiently taken up by macrophages and dendritic cells. In this study, we used iodine-125(125I)-labelled PMOs, designed a tripodna harbouring an 125I-PMO (125I-PMO/tripodna), and evaluated whether this tripodna could control the pharmacokinetic properties of PMO. Gel electrophoresis showed...

Construction of nanostructured DNA harbouring phosphorodiamidate morpholino oligonucleotide for controlled tissue distribution in mice

Yosuke Takahashi, Yuki Araie, Daiki Nomura, Yuki Takahashi, Kohei Sano, Hideo Saji, Yoshinobu Takakura & Makiya Nishikawa
Phosphorodiamidate morpholino oligonucleotides (PMOs) are a class of antisense oligonucleotides used in the treatment of neuromuscular diseases. Their major drawbacks are high blood clearance and poor cellular delivery. Previously, we demonstrated that tripod-like nanostructured DNA, or tripodna, was efficiently taken up by macrophages and dendritic cells. In this study, we used iodine-125(125I)-labelled PMOs, designed a tripodna harbouring an 125I-PMO (125I-PMO/tripodna), and evaluated whether this tripodna could control the pharmacokinetic properties of PMO. Gel electrophoresis showed...

surveyRawData.csv

Stéphane Boyer
Anonymous online survey

Codes_for_Plos.zip

Haim Weissmann
Empirical analysis of vegetation dynamics and the possibility of a catastrophic desertification transition. - Codes

Codes_for_Plos.zip

Haim Weissmann
Empirical analysis of vegetation dynamics and the possibility of a catastrophic desertification transition. - Codes

Gender matters in the transition to employment for young adults with physical disabilities

Sally Lindsay, Elaine Cagliostro, Mikhaela Albarico, Neda Mortaji & Dilakshan Srikanthan
Purpose: The purpose of this study was to explore the role of gender in the transition to employment for young adults with physical disabilities. Methods: This study drew on in-depth interviews with a purposive sample of 33 participants (23 youth and 10 clinicians). The youth in our sample included 13 females (mean age 22.9) and 10 males (mean age 21.3) who had various types of physical disabilities. The person–environment–occupation (PEO) model informed our analysis. Results:...

Gender matters in the transition to employment for young adults with physical disabilities

Sally Lindsay, Elaine Cagliostro, Mikhaela Albarico, Neda Mortaji & Dilakshan Srikanthan
Purpose: The purpose of this study was to explore the role of gender in the transition to employment for young adults with physical disabilities. Methods: This study drew on in-depth interviews with a purposive sample of 33 participants (23 youth and 10 clinicians). The youth in our sample included 13 females (mean age 22.9) and 10 males (mean age 21.3) who had various types of physical disabilities. The person–environment–occupation (PEO) model informed our analysis. Results:...

EPSON Printer Help Desk Number +1-866-569-8043

Rosie Smith
Get the latest deal of printers from Epson collection. It offers wide range of functional features. But sometimes, it displaces from its track as its users are confronted to some technical issues. Resolve them by calling at +1-866-569-8043 toll free.
Epson Printer Help Number

EPSON Printer Help Desk Number +1-866-569-8043

Rosie Smith
Get the latest deal of printers from Epson collection. It offers wide range of functional features. But sometimes, it displaces from its track as its users are confronted to some technical issues. Resolve them by calling at +1-866-569-8043 toll free.
Epson Printer Help Number

Canon Printer Helpline Number UK +44-808-281-8685 Canon Printer Contact Number UK

Olivia Wilde
Canon printer is an easy to use technology printer that suits you every printing need. If you confront to any technical problem in it, come to us at Canon Printer Customer Support Number UK. You just need to dial our number for instant assistance.

Canon Printer Helpline Number UK +44-808-281-8685 Canon Printer Contact Number UK

Olivia Wilde
Canon printer is an easy to use technology printer that suits you every printing need. If you confront to any technical problem in it, come to us at Canon Printer Customer Support Number UK. You just need to dial our number for instant assistance.

Viscosity reduction of isotonic solutions of the photosensitizer TPCS2a by cyclodextrin complexation

Marianne Lilletvedt Tovsen, Ingunn Tho & Hanne Hjorth Tønnesen
Meso-tetraphenyl chlorin disulphonate (TPCS2a) is a photosensitizer (PS) particularly developed and patented for use in the technology of photochemical internalization (PCI) against cancer. TPCS2a is known to aggregate in aqueous media even at low concentrations (≥0.1 µM) and to form a high-viscosity network at clinically relevant concentrations (mM). The aim of this work was to evaluate the effect of two hydroxypropylated cyclodextrin derivatives of beta and gamma type, respectively i.e. HPβCD and HPγCD, on the aggregation...

Viscosity reduction of isotonic solutions of the photosensitizer TPCS2a by cyclodextrin complexation

Marianne Lilletvedt Tovsen, Ingunn Tho & Hanne Hjorth Tønnesen
Meso-tetraphenyl chlorin disulphonate (TPCS2a) is a photosensitizer (PS) particularly developed and patented for use in the technology of photochemical internalization (PCI) against cancer. TPCS2a is known to aggregate in aqueous media even at low concentrations (≥0.1 µM) and to form a high-viscosity network at clinically relevant concentrations (mM). The aim of this work was to evaluate the effect of two hydroxypropylated cyclodextrin derivatives of beta and gamma type, respectively i.e. HPβCD and HPγCD, on the aggregation...

Identifying novel small molecule antagonists for mLST8 protein using computational approaches

Tuleshwori Devi Sapam, Anbumani Velmurugan Ilavarasi, Bhagath Kumar Palaka, Elakkiya Elumalai, Nirmala Devi Kanika & Dinakara Rao Ampasala
Mammalian lethal with SEC13 protein 8 (mLST8), is an indispensable protein subunit of mammalian target of rapamycin (mTOR) signaling pathway that interacts with the kinase domain of mTOR protein, thereby stabilizing its active site. Experimental studies reported the over expression of mLST8 in human colon and prostate cancers by activation of both mTORC1/2 complexes and subsequent downstream substrates leading to tumor progression. Considering its role, targeting mLST8 protein would be a therapeutic approach against tumor...

Identifying novel small molecule antagonists for mLST8 protein using computational approaches

Tuleshwori Devi Sapam, Anbumani Velmurugan Ilavarasi, Bhagath Kumar Palaka, Elakkiya Elumalai, Nirmala Devi Kanika & Dinakara Rao Ampasala
Mammalian lethal with SEC13 protein 8 (mLST8), is an indispensable protein subunit of mammalian target of rapamycin (mTOR) signaling pathway that interacts with the kinase domain of mTOR protein, thereby stabilizing its active site. Experimental studies reported the over expression of mLST8 in human colon and prostate cancers by activation of both mTORC1/2 complexes and subsequent downstream substrates leading to tumor progression. Considering its role, targeting mLST8 protein would be a therapeutic approach against tumor...

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