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Dependence of cell doubling time on generation number for old pole and new pole daughter cells.

Stefano Pagliara
Old pole daughter cells took longer to divide than new pole daughter cells (our linear mixed model analysis returned χ2df=1 =5.192, p = 0.023). For both cell types, division time progressively increased over successive generations (our linear mixed model analysis returned χ2df=1 = 38.327, p < 0.001). This analysis was carried out including data for generations 2 to 11 from two experimental runs.

Dependence of cell doubling time on generation number for old pole and new pole daughter cells.

Stefano Pagliara
a) Old pole daughter cells took longer to divide than new pole daughter cells (our linear mixed model analysis returned χ2df=1 =5.192, p = 0.023). For both cell types, division time progressively increased over successive generations (our linear mixed model analysis returned χ2df=1 = 38.327, p < 0.001). This analysis was carried out including data for generations 2 to 11 from two experimental runs.
(b) Inspecting the 24-generation data set revealed that the progressive increase in...

Dependence of cell doubling time on generation number for old pole and new pole daughter cells.

Stefano Pagliara
a) Old pole daughter cells took longer to divide than new pole daughter cells (our linear mixed model analysis returned χ2df=1 =5.192, p = 0.023). For both cell types, division time progressively increased over successive generations (our linear mixed model analysis returned χ2df=1 = 38.327, p < 0.001). This analysis was carried out including data for generations 2 to 11 from two experimental runs.
(b) Inspecting the 24-generation data set revealed that the progressive increase in...

New and old pole daughters differ in their glucose uptake patterns

Stefano Pagliara
Uptake of the fluorescent glucose analogue 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG) in 40 pairs of old pole and b) generation-matched new pole daughter cells collated from three independent mother machine experiments. Each pair was hosted in a different dead-end channel of the mother machine and constituted the 4th generation grown in the mother machine from an E. coli overnight culture. 2-NBDG was introduced in the mother machine at t = 0s.

New and old pole daughters differ in their glucose uptake patterns

Stefano Pagliara
Uptake of the fluorescent glucose analogue 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG) in 40 pairs of old pole and b) generation-matched new pole daughter cells collated from three independent mother machine experiments. Each pair was hosted in a different dead-end channel of the mother machine and constituted the 4th generation grown in the mother machine from an E. coli overnight culture. 2-NBDG was introduced in the mother machine at t = 0s. (c) At the end of each experiment...

New and old pole daughters differ in their glucose uptake patterns

Stefano Pagliara
Uptake of the fluorescent glucose analogue 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG) in 40 pairs of old pole and b) generation-matched new pole daughter cells collated from three independent mother machine experiments. Each pair was hosted in a different dead-end channel of the mother machine and constituted the 4th generation grown in the mother machine from an E. coli overnight culture. 2-NBDG was introduced in the mother machine at t = 0s.

Latest trends in repositories and data

Alan Hyndman
At Figshare we are always developing new features and initiatives to meet the needs of the repository and data community. We work with institutions, publishers, funders, government agencies, and researchers which gives us a unique insight into how the space is rapidly evolving.

In this webinar we would like to share some of these insights with you including how we develop the platform to meet these changing needs and some of our exciting plans for the...

Latest trends in repositories and data

Alan Hyndman
At Figshare we are always developing new features and initiatives to meet the needs of the repository and data community. We work with institutions, publishers, funders, government agencies, and researchers which gives us a unique insight into how the space is rapidly evolving.

In this webinar we would like to share some of these insights with you including how we develop the platform to meet these changing needs and some of our exciting plans for the...

d'Hondt et. al (2019) - Persuasive message elements

Jens D'Hondt
This dataset includes the list of persuasive message elements implemented in the APMS as discussed in the study 'Evaluation of computer-tailored motivational messaging in a health promotion context' by d'Hondt et. al (2019).

d'Hondt et. al (2019) - Challenge list

Jens D'Hondt
This dataset includes the list of challenges/activities available to participants in the intervention discussed in the study 'Evaluation of computer-tailored motivational messaging in a health promotion context' by d'Hondt et. al (2019).

d'Hondt et. al (2019) - Challenge list

Jens D'Hondt
This dataset includes the list of challenges/activities available to participants in the intervention discussed in the study 'Evaluation of computer-tailored motivational messaging in a health promotion context' by d'Hondt et. al (2019).

d'Hondt et. al (2019) - Persuasive message elements

Jens D'Hondt
This dataset includes the list of persuasive message elements implemented in the APMS as discussed in the study 'Evaluation of computer-tailored motivational messaging in a health promotion context' by d'Hondt et. al (2019).

d'Hondt et. al (2019) - Persuasive message elements

Jens D'Hondt
This dataset includes the list of persuasive message elements implemented in the APMS as discussed in the study 'Evaluation of computer-tailored motivational messaging in a health promotion context' by d'Hondt et. al (2019).

B-, N-doped and BN codoped C60 heterofullerenes for environmental monitoring of NO and NO2: a DFT study

Mehdi D. Esrafili & Hossein Janebi
Using density functional theory calculations, we investigate the gas sensing performance of B-, N-doped and BN-codoped C60 fullerenes towards NO and NO2 molecules. The calculated adsorption energies and net charge-transfer values indicate that NO and NO2 molecules have a stronger interaction with the BN-codoped fullerenes compared to the B- or N-doped ones. It is also found that the electronic properties of the BN-codoped C60 exhibit a larger sensitivity towards NO and NO2 molecules. An increase...

B-, N-doped and BN codoped C60 heterofullerenes for environmental monitoring of NO and NO2: a DFT study

Mehdi D. Esrafili & Hossein Janebi
Using density functional theory calculations, we investigate the gas sensing performance of B-, N-doped and BN-codoped C60 fullerenes towards NO and NO2 molecules. The calculated adsorption energies and net charge-transfer values indicate that NO and NO2 molecules have a stronger interaction with the BN-codoped fullerenes compared to the B- or N-doped ones. It is also found that the electronic properties of the BN-codoped C60 exhibit a larger sensitivity towards NO and NO2 molecules. An increase...

d'Hondt et. al (2019) - Challenge list

Jens D'Hondt
This dataset includes the list of challenges/activities (including the amount of points rewarded upon completion) available to the participants of the study 'Evaluation of computer-tailored motivational messaging in a health promotion context' by d'Hondt et. al (2019).

Analytical evaluation and clinical application of insulin and C-peptide by a whole blood, lateral flow, point of care (POC) assay system

Dong Wook Jekarl, Hyunyu Choi, Eun Sook Kim, Seungok Lee, Hae-Il Park, Myungshin Kim & Yonggoo Kim
The analytical performance and clinical application of measuring insulin and connecting peptide (C-peptide) by point of care (POC) assay were evaluated. A POC assay system (SelexOn, Osang Healthcare Inc., Anyang-si, Korea) was evaluated for precision, linearity, limit of blank (LOB), and limit of detection (LOD). Method comparison was performed with the Cobas Elecsys insulin and C-peptide assay (Roche Diagnostics GmbH, Mannheim, Germany) using 215 and 201 patient specimens for insulin and C-peptide, respectively. For clinical...

Analytical evaluation and clinical application of insulin and C-peptide by a whole blood, lateral flow, point of care (POC) assay system

Dong Wook Jekarl, Hyunyu Choi, Eun Sook Kim, Seungok Lee, Hae-Il Park, Myungshin Kim & Yonggoo Kim
The analytical performance and clinical application of measuring insulin and connecting peptide (C-peptide) by point of care (POC) assay were evaluated. A POC assay system (SelexOn, Osang Healthcare Inc., Anyang-si, Korea) was evaluated for precision, linearity, limit of blank (LOB), and limit of detection (LOD). Method comparison was performed with the Cobas Elecsys insulin and C-peptide assay (Roche Diagnostics GmbH, Mannheim, Germany) using 215 and 201 patient specimens for insulin and C-peptide, respectively. For clinical...

Synthesis of podophyllotoxin-glycosyl triazoles via click protocol mediated by silver (I)-N-heterocyclic carbenes and their anticancer evaluation as topoisomerase-II inhibitors

Srinivas Nerella, Shravankumar Kankala & Brahmeshwari Gavaji
Herein we report the regioselective synthesis of podophyllotoxin-Glycosyl triazole hybrids catalysed by Ag(I)-N-heterocyclic carbene (Ag(I)-NHC) in a short reaction time (∼30 min) at ambient conditions. In principle, it is the first report of Click alkyne-azide cycloaddition catalysed by Ag(I)-NHC catalyst and moreover, this new methodology yielded good results when compared with traditional CuAAC in terms of reaction time and selectivity. The synthesised compounds were further explored for in vitro anticancer activity against four human cancer cell...

Synthesis of podophyllotoxin-glycosyl triazoles via click protocol mediated by silver (I)-N-heterocyclic carbenes and their anticancer evaluation as topoisomerase-II inhibitors

Srinivas Nerella, Shravankumar Kankala & Brahmeshwari Gavaji
Herein we report the regioselective synthesis of podophyllotoxin-Glycosyl triazole hybrids catalysed by Ag(I)-N-heterocyclic carbene (Ag(I)-NHC) in a short reaction time (∼30 min) at ambient conditions. In principle, it is the first report of Click alkyne-azide cycloaddition catalysed by Ag(I)-NHC catalyst and moreover, this new methodology yielded good results when compared with traditional CuAAC in terms of reaction time and selectivity. The synthesised compounds were further explored for in vitro anticancer activity against four human cancer cell...

Dataset: Impact of a structured HIV testing program in a hospital emergency department and a primary care center

Javier Martínez Sanz
Dataset: Impact of a structured HIV testing program in a hospital emergency department and a primary care center

Dataset: Impact of a structured HIV testing program in a hospital emergency department and a primary care center

Javier Martínez Sanz
Dataset: Impact of a structured HIV testing program in a hospital emergency department and a primary care center

The Jewels of Ninkarrak

Giorgio Buccellati & Marilyn Kelly-Buccellati
Archaelogy at UCLA, 1 (21): 1–4.

The Jewels of Ninkarrak

Giorgio Buccellati & Marilyn Kelly-Buccellati
Archaelogy at UCLA, 1 (21): 1–4.

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