164,945 Works

Can a low-cost eye-tracker "stand-up" to a mobile test of precision and accuracy

Shannon Collins, Audrey Hooks & Jake Kurczek
However, new low-cost tracking is now making eye tracking more accessible and mobile. Previous research (Dalmaijer, 2015) indicated that both the EyeTribe and the EyeLink ($40,000 high quality eye tracker) had similar spatial precision and accuracy, region of interest and pupilometry analysis abilities. In the present experiment we tested the low-cost tracker (EyeTribe) in both a standard and “mobile” (i.e. standing/holding tablet) conditions in hopes to validate its potential use outside the lab (e.g., sideline...

Can a low-cost eye-tracker "stand-up" to a mobile test of precision and accuracy

Shannon Collins, Audrey Hooks & Jake Kurczek
However, new low-cost tracking is now making eye tracking more accessible and mobile. Previous research (Dalmaijer, 2015) indicated that both the EyeTribe and the EyeLink ($40,000 high quality eye tracker) had similar spatial precision and accuracy, region of interest and pupilometry analysis abilities. In the present experiment we tested the low-cost tracker (EyeTribe) in both a standard and “mobile” (i.e. standing/holding tablet) conditions in hopes to validate its potential use outside the lab (e.g., sideline...

Spontaneous eyeblink rate as a predictor of dopamine: Individual differences across previous collision sport history

Audrey Hooks, Shannon Collins & Jake Kurczek
Humans and animals identify, pursue and achieve rewards and learn from rewarded experiences through a reward system The mesolimbic reward system is responsible for a number of psychological mechanisms including hedonic response to reward and incentive salience or colloquially liking and wanting Eye-blink rate is a reliable proxy for dopaminergic functioning (Taylor et al., 1999) Altered dysfunction has been detected in a number of clinical populations, including schizophrenia (Chen, Lam, Chen, & Nguyen, 1996), and...

Spontaneous eyeblink rate as a predictor of dopamine: Individual differences across previous collision sport history

Audrey Hooks, Shannon Collins & Jake Kurczek
Humans and animals identify, pursue and achieve rewards and learn from rewarded experiences through a reward system The mesolimbic reward system is responsible for a number of psychological mechanisms including hedonic response to reward and incentive salience or colloquially liking and wanting Eye-blink rate is a reliable proxy for dopaminergic functioning (Taylor et al., 1999) Altered dysfunction has been detected in a number of clinical populations, including schizophrenia (Chen, Lam, Chen, & Nguyen, 1996), and...

Assessing and validating a 3D motion tracking balance assessment.

Angela Richardson, Thomas Johnson & Jake Kurczek
Previous research has investigated the BESS and found that scores were highly varied across experimenters.
This research reveals a number of potential flaws within the BESS. Beyond the problems of subjective scoring, the BESS only detects dysfunction so that most healthy people and even people affected by mild concussions score perfectly well on the test.
In the present experiment, we look to assess the BESS test and compare subjective assessment of balance ability.
By identifying...

Assessing and validating a 3D motion tracking balance assessment.

Angela Richardson, Thomas Johnson & Jake Kurczek
Previous research has investigated the BESS and found that scores were highly varied across experimenters.
This research reveals a number of potential flaws within the BESS. Beyond the problems of subjective scoring, the BESS only detects dysfunction so that most healthy people and even people affected by mild concussions score perfectly well on the test.
In the present experiment, we look to assess the BESS test and compare subjective assessment of balance ability.
By identifying...

organic-coconut-logo.jpg

Organic Coconut
The Coconut Cooperative was founded in 2014 with the goal of connecting organic coconut farmers with consumers across the world. Coconut farming plays a major economic role in tropic and subtropic countries, and while the spike in global demand of coconuts has led to a surge in production, it is imperative to ensure the survival of one of Southeast Asia's most precious resources. To this end, we directly contribute and partner with organizations across Southeast...

organic-coconut-logo.jpg

Organic Coconut
The Coconut Cooperative was founded in 2014 with the goal of connecting organic coconut farmers with consumers across the world. Coconut farming plays a major economic role in tropic and subtropic countries, and while the spike in global demand of coconuts has led to a surge in production, it is imperative to ensure the survival of one of Southeast Asia's most precious resources. To this end, we directly contribute and partner with organizations across Southeast...

Additional file 9: of Atp8 is in the ground pattern of flatworm mitochondrial genomes

Bernhard Egger, Lutz Bachmann & Bastian Fromm
Amino acid alignment of atp8 in flatworms and other lophotrochozoans: a gastrotrich (Lepidodermella squamata), annelids (Platynereis dumerilii and Sipunculus nudus), molluscs (Sepiella japonica and Ascobulla fragilis), a phoronid (Phoronopsis harmeri), a kamptozoan (Loxosomella aloxiata), a bryozoan (Bugula neritina), a brachiopod (Terebratalia transversa) and a nemertean (Micrura bella). Putative triclad atp8 sequences were extracted from Ross et al. [5]. (TIF 129 kb)

Additional file 8: of Atp8 is in the ground pattern of flatworm mitochondrial genomes

Bernhard Egger, Lutz Bachmann & Bastian Fromm
Mitochondrial gene order in macrostomorphans, showing the newly sequenced complete mitochondrial genome of Macrostomum lignano and the partial mitochondrial genome of Microstomum lineare [8]. The gene order between these two members of Macrostomorpha is not conserved. (TIF 133 kb)

Additional file 6: of Atp8 is in the ground pattern of flatworm mitochondrial genomes

Bernhard Egger, Lutz Bachmann & Bastian Fromm
Hydrophobicity profiles of the six putative atp8 amino acid sequences of free-living flatworms (A-F) and of two representative published atp8 amino acid sequences, from a mollusc (G) and an annelid (H). (TIF 101 kb)

Additional file 2: of Atp8 is in the ground pattern of flatworm mitochondrial genomes

Bernhard Egger, Lutz Bachmann & Bastian Fromm
Circular mitochondrial genome of Prosthiostomum siphunculus [2]. Outermost circle displays logarithmically mapped RNAseq reads. tRNA genes are abbreviated with tRNA and three letters and a number if applicable. Colours indicate the widely conserved gene cartridges proposed by Mwinyi et al. [18]. Unlabeled and uncoloured regions are intergenic spacers. (TIF 870 kb)

Additional file 6: Figure S4. of Quantitative analysis of cryptic splicing associated with TDP-43 depletion

Jack Humphrey, Warren Emmett, Pietro Fratta, Adrian Isaacs & Vincent Plagnol
Motif finding with HOMER The top ten motifs reported by the algorithm when comparing flanked cryptic exons with adjacent intronic sequence. The red asterisk indicates that the motif is potentially a false positive result. (TIF 1799 kb)

Additional file 9: of MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway

Zhen Liang, Xiao Wang, Xin Xu, Bo Xie, Alin Ji, Shuai Meng, Shiqi Li, Yi Zhu, Jian Wu, Zhenghui Hu, Yiwei Lin, Xiangyi Zheng, Liping Xie & Ben Liu
Figure S7. Flow cytometric analysis showed that the overexpression of FLOT1 by pFLOT1 could reverse the suppression of cell proliferation caused by miR-608. Error bars represent the S.D. from three independent experiments. *Pâ

Additional file 8: of MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway

Zhen Liang, Xiao Wang, Xin Xu, Bo Xie, Alin Ji, Shuai Meng, Shiqi Li, Yi Zhu, Jian Wu, Zhenghui Hu, Yiwei Lin, Xiangyi Zheng, Liping Xie & Ben Liu
Figure S6. Western blot analysis showed that the down-regulation of miR-608 could partially reverse the p-FOXO3a down-regulation caused by siFLOT1. (JPG 218 kb)

Additional file 7: of MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway

Zhen Liang, Xiao Wang, Xin Xu, Bo Xie, Alin Ji, Shuai Meng, Shiqi Li, Yi Zhu, Jian Wu, Zhenghui Hu, Yiwei Lin, Xiangyi Zheng, Liping Xie & Ben Liu
Figure S5. Flow cytometric analysis showed that the co-transfection of another 3 different non-overlapping siFLOT1 together could also cause the similar G1 arrest as miR-608 did in Bca cells. Error bars represent the S.D. from three independent experiments. *Pâ

Additional file 6: of MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway

Zhen Liang, Xiao Wang, Xin Xu, Bo Xie, Alin Ji, Shuai Meng, Shiqi Li, Yi Zhu, Jian Wu, Zhenghui Hu, Yiwei Lin, Xiangyi Zheng, Liping Xie & Ben Liu
Figure S4. Western blot analysis showed that the co-transfection of another 3 different non-overlapping siFLOT1 could also significantly down-regulate AKT/FOXO3a signaling related proteins in T24 and UM-UC-3 cell lines. (JPG 783 kb)

Additional file 3: of Thoracolumbar epidural anaesthesia with 0.5% bupivacaine with or without methadone in goats

Priscila Dos Santos Silva, Paulo Fantinato-Neto, AndrĂŠ Silva, Eduardo Junior & Adriano Carregaro
A pair of subcutaneous needles, positioned on the radial region, which was used as positive control. (JPG 1137 kb)

Additional file 6: Fig. S3. of Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma

Laurens Sand, Tessa Buckle, Fijs Leeuwen, Willem Corver, Alwine Kruisselbrink, Aart Jochemsen, Pancras Hogendoorn & Károly Szuhai
Western blot analysis of CXCR4 protein expression with N- and C-terminal directed antibodies. Western blot analysis of CXCr4 protein expression in high CXCR4 expressing Ewing sarcoma cell line IARC-EW3, medium CXCR4 expressing breast cancer cell line MDA-MB-468 and low CXCR4 expressing Ewing cell line IARC-EW7 (supplementary results [10]) using two N-terminal antibodies (Ab2074 and NBP1–76867) and one C-terminal antibody (UMB2). Theoretical molecular weight of CXCR4–2 is 39 kDa. No conclusive results could be obtained with any...

Additional file 4: of MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway

Zhen Liang, Xiao Wang, Xin Xu, Bo Xie, Alin Ji, Shuai Meng, Shiqi Li, Yi Zhu, Jian Wu, Zhenghui Hu, Yiwei Lin, Xiangyi Zheng, Liping Xie & Ben Liu
Figure S3. The level of miR-608 after the transfection of miR-608 inhibitor was assessed by qRT-PCR. Error bars represent the S.D. from three independent experiments. *Pâ

Additional file 2: of Thoracolumbar epidural anaesthesia with 0.5% bupivacaine with or without methadone in goats

Priscila Dos Santos Silva, Paulo Fantinato-Neto, AndrĂŠ Silva, Eduardo Junior & Adriano Carregaro
A pair of subcutaneous needles, positioned on the goat's left flank, through which noxious stimulus was applied. (JPG 2084 kb)

Additional file 4: Fig. S2. of Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma

Laurens Sand, Tessa Buckle, Fijs Leeuwen, Willem Corver, Alwine Kruisselbrink, Aart Jochemsen, Pancras Hogendoorn & Károly Szuhai
Influence of methanol fixation after MSAP-Ac-TZ14011 staining. EWS cell line A673 and MDA-MB-231 X4 were stained with MSAP-Ac-TZ14011 and subsequently were (black) or were not (gray) fixed with methanol. Methanol fixation of the cells lead to increased fluorescence levels. The Y-axis represents the normalized number of cell counts (n = 1). (EPS 1315 kb)

Additional file 1: of Thoracolumbar epidural anaesthesia with 0.5% bupivacaine with or without methadone in goats

Priscila Dos Santos Silva, Paulo Fantinato-Neto, AndrĂŠ Silva, Eduardo Junior & Adriano Carregaro
X-ray showing the correct position of the catheter into the thoracolumbar space (red arrow). (JPEG 1397 kb)

Additional file 3: of MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway

Zhen Liang, Xiao Wang, Xin Xu, Bo Xie, Alin Ji, Shuai Meng, Shiqi Li, Yi Zhu, Jian Wu, Zhenghui Hu, Yiwei Lin, Xiangyi Zheng, Liping Xie & Ben Liu
Figure S2. Western blot analysis showed that LY294002 significantly activated FOXO3a. (JPG 743 kb)

Additional file 3: Fig. S1. of Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma

Laurens Sand, Tessa Buckle, Fijs Leeuwen, Willem Corver, Alwine Kruisselbrink, Aart Jochemsen, Pancras Hogendoorn & Károly Szuhai
Validation to show the effect of cell harvesting procedure on detected MSAP-Ac-TZ14011 and ab2074 signal intensities. The effect of 10 μM EDTA (green), TripLE (red) and 0.025% trypsin (blue) treatment on the fluorescence of ab2074 (*) and MSAP-Ac-TZ14011 staining were tested on (A) MDA-MB-231 X4, (B) TC32 and (C) A673. As representative baseline (black), the result of TripLE treatment without additional staining was used. No significant difference in fluorescence was observed. The Y-axis represents the normalized...

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