1,586 Works

Quantification of silver nanoparticle uptake and distribution within individual human macrophages by FIB/SEM slice and view

Erik Gührs, Michael Schneider, Christian M. Günther, Piet Hessing, Karen Heitz, Doreen Wittke, Ana López-Serrano Oliver, Norbert Jakubowski, Johanna Plendl, Stefan Eisebitt & Andrea Haase
Background Quantification of nanoparticle (NP) uptake in cells or tissues is very important for safety assessment. Often, electron microscopy based approaches are used for this purpose, which allow imaging at very high resolution. However, precise quantification of NP numbers in cells and tissues remains challenging. The aim of this study was to present a novel approach, that combines precise quantification of NPs in individual cells together with high resolution imaging of their intracellular distribution based...

Aufgemärkt!! Aufgemärkt!!; 1968

(:Unav)
Enthält u. a.: Misstrauen der Berliner Burschenschaft der Märker gegenüber der Finanzierung der Reinigungskosten für den Vietnamkongress durch die Studentenvertretung der TU Berlin aus Spendenmitteln der APO.-Artikel im Tagesspiegel vom 24. April 1968.- Forderung einer öffentlichen Rechnungslegung.- Internationaler Vietnam-Kongress. 1 Seite. S/w.

Reconstruction of the lantibiotic ruminococcin-A biosynthesis machinery in Escherichia coli and structural characterization

Elvis Legala Ongey
Lanthipeptides are a group of therapeutically relevant proteinaceous compounds predominantly produced by Gram-positive bacteria at the ribosomal level, containing thioether cross-linked amino acids called lanthionine as a characteristic structural element. Lanthipeptides are attracting growing interests stemming from their wide range of bioactivities including antimicrobial, antiviral and anticancer. However, purifying them from native sources is challenging due low production yields and cultivation difficulties that accompany the natural producers. Ruminococcin-A (RumA) is an example which is naturally...

Fossil-fueled development (SSP5): an energy and resource intensive scenario for the 21st century

Elmar Kriegler, Nico Bauer, Alexander Popp, Florian Humpenöder, Marian Leimbach, Jessica Strefler, Lavinia Baumstark, Benjamin Leon Bodirsky, Jérôme Hilaire, David Klein, Ioanna Mouratiadou, Isabelle Weindl, Christoph Bertram, Jan-Philipp Dietrich, Gunnar Luderer, Michaja Pehl, Robert Pietzcker, Franziska Piontek, Hermann Lotze-Campen, Anne Biewald, Markus Bonsch, Anastasis Giannousakis, Ulrich Kreidenweis, Christoph Müller, Susanne Rolinski … & Ottmar Edenhofer
This paper presents a set of energy and resource intensive scenarios based on the concept of Shared Socio-Economic Pathways (SSPs). The scenario family is characterized by rapid and fossil-fueled development with high socio-economic challenges to mitigation and low socio-economic challenges to adaptation (SSP5). A special focus is placed on the SSP5 marker scenario developed by the REMIND-MAgPIE integrated assessment modeling framework. The SSP5 baseline scenarios exhibit very high levels of fossil fuel use, up to...

Development of recombinant oncolytic Coxsackievirus B3 for treatment of colorectal carcinoma

Ahmet Hazini
Colorectal cancer is one of the most death related cancer type in worldwide. Conventional cancer therapeutics show curable effect only in the patients at early stage of the disease. In case of the diagnosis at late stages, the survival rate decreases dramatically up to 10%. Therefore, novel cancer therapeutics are urgently needed. Oncolytic virotherapy is a new treatment approach which exploits the viruses against cancer. Clinical trials prove the efficiency of various oncolytic viruses in...

Revolutionäre Architektur; 1968

(:Unav)
Enthält: Aufruf der Fakultät III Architektur vom 9. Juni 1968: Revolutionäre Architektur wird auf der Strasse gemeacht. Baut Barrikaden. 1 Seite. S/w.

Aeroakustische Auslegung von Triebwerksfans mittels multidisziplinärer Optimierungen

Robert Jaron
Fan noise is the dominant noise source in modern aircraft engines with high bypass ratios. Therefore the consideration of the noise reduction during the design of a fan stages becomes more and more important. In state-of-the-art design processes of fan stages the aerodynamic performance and the mechanical stability is automatically optimized by means of numerical simulations of the parametrized fan stage. To enable also the consideration of the fan noise during the optimization a method...

Studies on shape defined Pt-alloy based nanoparticles for the electrochemical reduction of oxygen

Vera Beermann
Fuel cells represent an almost ideal technology to provide electricity from sustainable energies. However, to date expensive platinum catalysts are used which do not provide sufficient performances at the cathode side where the oxygen reduction reaction (ORR) takes place. A cost-efficient and active alternative is represented by the group of Pt-Ni alloys. Octahedral shaped Pt-Ni alloy nanoparticles exhibit further improved oxygen reduction reaction activities in comparison to their spherical shaped counterparts. This work dealt with...

Braess's Paradox in an Agent-based Transport Model

Theresa Thunig & Kai Nagel
Braess's paradox states that adding a link to the network can increase total travel time in a user equilibrium. In this paper, Braess's paradox is analyzed in the agent-based transport simulation MATSim. It can be observed, that two different types of the paradox occur: In the absence of spill back effects, the delay per agent caused by adding a new link is bounded, i.e. the delay per agent will not increase by extending the time...

Route Guidance Map for Emergency Evacuation

Amit Agarwal & Nomesh B. Bolia
An efficient process of emergency evacuation must be guided. In the event of an evacuation instruction, a significant amount of time is spent by evacuees looking for a place of relative safety or an exit. Due to the ensuing stress and confusion evacuees try to follow others, consequently, all the exits are not used effectively. Therefore, it is important to develop a route guidance map for the emergency. The focus of the map is to...

Renewable electricity and backup capacities: an (un-) resolvable problem?

Aaron J. Praktiknjo & Georg Erdmann
Public support for renewables has led to an unexpected investment momentum in Germany. A consequence is reduced wholesale electricity prices, the so-called merit order effect of renewables.We estimate this reduction using an econometric approach and give a quantitative overview of the financial situation of conventional generators. Our results indicate that investments in new conventional capacities are economically unviable. With the current market design, this situation is going to impact supply security at least in the...

Large-scale microscopic simulation of taxi services. Berlin and Barcelona case studies

Michał Maciejewski, Josep Maria Salanova, Joschka Bischoff & Miquel Estrada
The paper presents research on large-scale microscopic simulation of taxi services in Berlin and Barcelona based on floating car data collected by local taxi fleets. Firstly, Berlin’s and Barcelona’s taxi markets are shortly described and the demand and supply data obtained from FCD analysed. Secondly, the online taxi dispatching problem formulation for this specific case is given, followed by the definition of two real-time rule-based heuristics used to dispatch taxis dynamically within the simulation. Finally,...

Mobile multi-parameter measurements for the dynamic analysis of gradients in brewing vessels

Anika Bockisch
Industrial processes have to be competitive and thus efficient. Products have to be produced with a high reproducibility and quality. At the same time, the scale of these processes reaches up to several 100 m³ and was even increasing in recent years. This is challenging since the power input is limited in large-scale processes. Therefore, mixing times are increasing in parallel to the volume, whereas heat and mass transfer rates are decreasing. This leads to...

Biologisch-chemische Behandlung von Prozeßwässern der Altlastensanierung sowie von kontaminierten Grundwässern

Joachim Behrendt
An einer vierstufigen Laborversuchsanlage, stehend aus einem Airlift-Schlaufensuspensionsreaktor (ASSR), einem Festbettumlaufreaktor (FBR 1), einem Schlaufenreaktor, der mit ozonhaltigem Sauerstoff begast wurde, (O3R) und einem weiteren Festbettumlaufreaktor (FBR 2), wurden Versuche zum Abbau und zur chemischen Oxidation mit nachfolgendem biologischen Abbau von Inhaltsstoffen aus Prozeßwässern der Altlastensanierung durchgeführt. Die Untersuchungen erfolgten an drei unterschiedlichen Wässern: - einem synthetisch kontaminierten Grundwasser, das durch Emulgieren eines PAK-haltigen Ölkonzentrats vom Sanierungsgelände der ehemaligen Firma Pintsch GmbH hergestellt wurde (Gintsch-Grundwasser),...

Hochschulreform auch für Ausländer; 1968

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Enthält u. a.: Einladung des Aussenreferats der Studentenvertretung der Technischen Universität (TU) Berlin zu einem Seminar Hochschulreform auch für Ausländer am 31. Jan. 1968 in der Studentenstadt Siegmundshof.- Seminar in Zusammenarbeit mit dem Akademischen Auslandsamt der TU Berlin.- Auflistung der Diskussionsthemen. 1 Seite. S/w.

Flatternde Talare. Große Aufregung um eine gestörte Rektoratsfeier; 1967

Heinrich Braune & [Peter] Riecker
Enthält u. a.: Darstellung der gestörten Rektoratsfeier am der Hamburger Universität und ihre Hintergründe von Heinrich Braune, Hamburg.- Unter den Talaren Muff von 1000 Jahren.- Proteste der Bergarbeiter im Ruhrgebiet.- Gewerkschaften.- Mitbestimmung der Studenten.- Auszug aus: Sozialdemokratischer Pressedienst vom 14. Nov. 1967. 1 Seite. S/w.

Anti-adenoviral artificial microRNAs Expressed from AAV9 vectors inhibit human adenovirus infection in immunosuppressed Syrian hamsters

Katrin Schaar, Anja Geisler, Milena Kraus, Sandra Pinkert, Markian Pryshliak, Jacqueline F. Spencer, Ann E. Tollefson, Baoling Ying, Jens Kurreck, William S. Wold, Robert Klopfleisch, Karoly Toth & Henry Fechner
Infections of immunocompromised patients with human adenoviruses (hAd) can develop into life-threatening conditions, whereas drugs with anti-adenoviral efficiency are not clinically approved and have limited efficacy. Small double-stranded RNAs that induce RNAi represent a new class of promising anti-adenoviral therapeutics. However, as yet, their efficiency to treat hAd5 infections has only been investigated in vitro. In this study, we analyzed artificial microRNAs (amiRs) delivered by self-complementary adeno-associated virus (scAAV) vectors for treatment of hAd5 infections...

Todesurteil für Teheraner Studenten; 1968

(:Unav)
Enthält u. a.: Darstellung der Iranischen Studenten Vereinigung (I.S.V.) zu Verhaftungen und Verhängung von Todesurteilen gegen Studierende und Akademiker der Teheraner Hochschulen.- Nachrichtensperre des iranischen Geheimdienstes SAVAK.- Verweis auf Konförderation Iranischer Studenten (CIS).- Aufruf zu Protest und Solidarität.- Schah-Regime. 1 Seite. S/w.

Solidarität. Erklärung auf der Vollversammlung; 1968

(:Unav)
Enthält u. a.: Erklärung des Cooperations-Seminar COOP an der Fakultät für Architektur auf der Vollversammlung der Berliner Studenten am 03.12.1968.- Darstellung ihrer bisherigen Arbeit.- Solidarisierung und Aufforderung zur Zusammenarbeit mit den Studenten der Filmakademie.- Reformseminare. 1 Seite. Überschrift nach Schablone, s/w.

Streik; 1968

(:Unav)
Enthält u. a.: Stellungnahme zur Verabschiedung der Notstandsgesetze und Aufruf zum Streik und zur Beteiligung an Veranstaltungen zur 2. Lesung der Notstandsgesetze im Bundestag am 15. Mai 1968. 1 Seite. S/w.

Characterization of the Cradle to Cradle Certified™ Products Program in the context of eco-labels and environmental declarations

Nikolay Minkov, Vanessa Bach & Matthias Finkbeiner
(1) Background: The Cradle to Cradle Certified™ Products Program (C2C Certified for short) is a scheme for the certification of products that meet the criteria and principles of the Cradle to Cradle® design approach. The objective of this paper is to characterize C2C Certified as an instrument for external communication in the context of environmental labeling and declarations. (2) Method: An eco-label characterization scheme consisting of 22 attributes was used to analyze C2C Certified. In...

Coexisting graphical and structured textual representations of requirements

Martin Beckmann, Christian Reuter & Andreas Vogelsang
[Context & motivation] Many requirements documents contain graphical and textual representations of requirements side-byside. These representations may be complementary but oftentimes they are strongly related or even express the same content. [Question/problem] Since both representation may be used on their own, we want to nd out why and how a combination of them is used in practice. In consequence, we want to know what advantages such an approach provides and whether challenges arise from the...

BIRKA-Flugblatt Nr. 4; 1968

Claus Hacker
Enthält u. a.: Aufruf der Basisgruppe Spandau der Arbeiter, Schüler und Studenten an die Arbeiter der BIRKA Regulatoren GmbH zum aktiven Einsatz gegen die Stilllegung des Werkes.- Beispiel AEG Mülheim-Saarn. 1 Seite. S/w.

VR-visualization of High-dimensional Urban Data

Louna Al Bondakji, Anna-Maria Chatzi, Minoo Heidari Tabar, Lisa-Marie Wesseler & Liss C. Werner
The project aims to investigate the possibility of VR in a combination of visualizing high-dimensional urban data. Our study proposes a data-based tool for urban planners, architects, and researchers to 3D visualize and experience an urban quarter. Users have a possibility to choose a specific part of a city according to urban data input like "buildings, streets, and landscapes". This data-based tool is based on an algorithm to translate data from Shapefiles (.sh) in a...

Kosten heute für Nutzen von gestern: das Auto in der Welt von morgen

G. Wolfgang Heinze & Heinrich H. Kill
Die wachsende Kritik an der Verkehrspolitik zeigt, dass Verkehrsinfrastruktur nicht nur als nationales Netz und internationale Verbindung dient, sondern auch als Lebensraum und als Netz von Kommunikationskanälen der Anwohner. Weil sie drängende Probleme lösten, begannen alle später dominierenden Verkehrsmittel mit einem Überschuss wahrgenommener gesellschaftlicher Nutzen über ihre wahrgenommenen gesellschaftlichen Kosten. Sie mussten individuell sehr attraktiv sein, aber erhielten ihre eigentlichen Systemstärken erst als Masseneffekte. Dieser Logik folgend, bietet sich heute die Wiedergewinnung des menschlichen Umfeldes...

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