213 Works

Elemental concentrations in fish from lakes in Northwest England

Jacky Chaplow
Data comprise concentrations of elements in ashed fish sampled from lakes in the English Lake District in 2012 and 2013. Fish were collected from three lakes (Windermere, Bassenthwaite Lake and Derwent Water) by the Centre for Ecology Hydrology (CEH) Lake Ecosystems group. Fish species collected were Roach (Rutilus rutilus), Perch (Perca fluviatilis), Ruffe (Gymnocephalus cernuus), Brown trout (Salmo trutta), Pike (Esox lucius) and Vendace (Coregonus albula). All samples were ashed prior to analysis by ICPMS...

Lung Tumours in Monkeys After Inhalation of Actinides

Michael Gruenberger
Purpose: To determine the risks of lung tumors after inhalation of different actinides. Status: 1972 - 1992 Treatment: Inhalation of Pu-239 dioxide (2.3μ AMAD, 0.6μ CMAD) prepared at 1000C Dosimetry: Activity inhaled, activity retained, calculated average lung doses Endpoints: Life-span study (spontaneous death) with macroscopic/microscopic pathology, sacrificed at terminal stage, radiographs of the thorax Animal: 59 male and female baboons (Papio papio) 2-4 years (2-10 kg) Results: A comparison of the early mortality (less than...

Radioecology data for wildlife and human assessments (UK)

Jacky Chaplow
Data comprise: Observations of Fukushima fallout in Great Britain, Element and radionuclide concentrations in representative species of the ICRP's Reference Animals and Plants and associated soils from a forest in north-west England, Exposure of burrowing mammals to Radon Rn-222 in Northwest England, Natural radionuclide concentrations in soil, water, sediment and biota in England and Wales, A database of radionuclide biological half-life values for wildlife, Post Chernobyl surveys of radiocaesium in soil, vegetation, wildlife and fungi...

A 'Reference Site' in the Chernobyl Exclusion Zone: radionuclide and stable element data, and estimated dose rates

Jacky Chaplow
Data comprise radionuclide activity concentrations, stable element concentrations and both radionuclide and stable element concentration ratios for vegetation and wildlife samples collected in the Chernobyl Exclusion Zone (CEZ) in 2014. Estimated absorbed dose rates for wildlife in the CEZ are also presented. Samples of soil, wild grass, earthworms, bees and other insects, small mammals, pine trees and frogs were collected in May and June 2014; frogspawn was collected in April 2015. Data were used to...

Early and Delayed Radiation Effects After Localised Irradiation of Pigs and Rabbits

Michael Gruenberger
Purpose: To study the early radiation-induced necrosis and late radiation-induced fibrosis of skin and underlying tissues after acute localized irradiation with a view to the management of accidental over-exposure of man Status: 1981 - Treatment: 1) Single collimated gamma exposure (Ir-192) (diameter 2 cm) of the outer side of the thigh and the back of pigs with skin surface doses from 0 to 140 Gy; 2) Single collimated gamma exposure (Ir-192) (diameter 2 cm) of...

NMRI low dose total body liver study

Omid Azimzadeh
Proteomic analysis of long-term and short-term effects of low dose ionizing radiation on NMRI mice livers.

Lung Tumors following Low-level Radon Exposure at Different Exposure Rates

Michael Gruenberger
Purpose: To study lung cancer risks under conditions simulating the situation in mines and highly exposed homes. Status: 1996-2002, data in ERA. Treatment: Inhalation of radon (0.1-0.3 μm AMAD 6.2% unattached) daily exposure for 6 hours 5 times per week as indicated under experimental groups. Endpoints: Life-span study (spontaneous death, some animals sacrificed) with macroscopic/microscopic pathology of the lung. Animal: Male Sprague-Dawley rats of different ages

Wildlife Transfer Database

Paul Schofield
An important factor in assessing the impact of radionuclides on the environment is the means to estimate the transfer of radionuclides to organisms. The WTD was developed to provide an online compilation of transfer parameters in the form of equilibrium-based whole-organism to media concentration ratios. The database contains information from more than 500 publications, more than 1400 species and a hundred thousand CRwo-media values.

German Thorotrast Study (rat data)

Mandy Birschwilks
There are data from four different animal studies with Thorotrast from the years 1975 - 1989 in rats.The study tracks key data, study design, number of animals, a list of responsible scientist and some references are already in the ERA database.Institution: Deutsches Krebsforschungszentrum, Heidelberg, Germany.Purpose: To determine the respective roles of the radioactive and chemical component in Thorotrast gel-induced tumours, alpha radioactivity in Thorotrast was enriched about 50 times by addition of Th-230.Thorotrast was the...

Elemental concentrations in fish from lakes in Northwest England

Jacky Chaplow
Data comprise concentrations of elements in ashed fish sampled from lakes in the English Lake District in 2012 and 2013. Fish were collected from three lakes (Windermere, Bassenthwaite Lake and Derwent Water) by the Centre for Ecology Hydrology (CEH) Lake Ecosystems group. Fish species collected were Roach (Rutilus rutilus), Perch (Perca fluviatilis), Ruffe (Gymnocephalus cernuus), Brown trout (Salmo trutta), Pike (Esox lucius) and Vendace (Coregonus albula). All samples were ashed prior to analysis by ICPMS...

Thyroid diseases near Semipalatinsk Nuclear Test Site - Data

Bernd Grosche
A description of the study is given in STOREDB:STUDY1008 (http://dx.doi.org/doi:10.20348/STOREDB/1108) . The data stored here include all the EXCEL and SPSS system files that were relevant for preparing the data used for Grosche et al., 2017 (http://www.storedb.org/store_v3/download.jsp?fileId=11331) . The steps taken for data preparation are described in http://www.storedb.org/store_v3/download.jsp?fileId=11333, the codebook is given in http://www.storedb.org/store_v3/download.jsp?fileId=11334. The original data set, including information of all 1,287 examinations which were carried out among 1,067 study participants is available in...

Quantitative proteomic analysis reveals induction of premature senescence in human umbilical vein endothelial cells exposed to chronic low-dose rate gamma-radiation

Omid Azimzadeh
Chronic low-dose ionizing radiation induces cardiovascular disease in human populations but the mechanism is largely unknown. We suggested that chronic radiation exposure may induce endothelial cell senescence that is associated with vascular damage in vivo. We investigated whether chronic radiation exposure is causing a change in the onset of senescence in endothelial cells in vitro. Indeed, when exposed to continuous low-dose rate gamma radiation (4.1 mGy/h) primary human umbilical vein endothelial cells (HUVECs) initiated senescence...

test

Michael Gruenberger
test only

Radiation-induced Endothelial Inflammation is Transferred via Secretome to Recipient Cells in a STAT-Driven Process

Jos
Irradiation is the most common treatment of cancer. However, minimizing the normal tissue injury, especially the damage to vascular endothelium, still remains a challenge. This study aimed to analyze direct and indirect radiation effects by investigating mechanisms of signal transfer from irradiated to non-irradiated endothelial cells by means of secreted proteins. It is known that human coronary artery endothelial cells (HCAECest2) undergo radiation-induced senescence 14 days post-exposure to 10 Gy X-rays. Proteomics analysis was performed...

Radioecology data for wildlife and human assessments (UK)

Jacky Chaplow
Data comprise: Observations of Fukushima fallout in Great Britain, Element and radionuclide concentrations in representative species of the ICRP's Reference Animals and Plants and associated soils from a forest in north-west England, Exposure of burrowing mammals to Radon Rn-222 in Northwest England, Natural radionuclide concentrations in soil, water, sediment and biota in England and Wales, A database of radionuclide biological half-life values for wildlife, Post Chernobyl surveys of radiocaesium in soil, vegetation, wildlife and fungi...

German Thorotrast Study (human data)

Mandy Birschwilks
The thorium-based radioactive contrast agent Thorotrast (R) was introduced in 1929 and applied worldwide until the 1950s, especially in angiography and arteriography. Due to the extremely long half-life of several hundred years and the life-long retention of the thorium dioxide particles in the human body, patients suffer lifetime internal exposure. The health effects from the incorporated thorium were investigated in a few cohort studies with a German study being the largest among them. This retrospective...

Post Chernobyl surveys of radiocaesium in soil, vegetation, wildlife and fungi in Great Britain

Jacky Chaplow
Data comprise radiocaesium concentrations in soil, vegetation, wildlife and fungi analysed from samples collected from throughout Great Britain after the 1986 Chernobyl accident by the Centre for Ecology and Hydrology (CEH), formerly the Institute of Terrestrial Ecology (ITE). National level vegetation surveys were conducted in May 1986, October 1986 and Spring 1987. More intensive surveys of vegetation (grass and heather) and wildlife (grouse, fox, etc.) in restricted areas were carried out in Cumbria, Wales and...

Wildlife Transfer Database

Paul Schofield
An important factor in assessing the impact of radionuclides on the environment is the means to estimate the transfer of radionuclides to organisms. The WTD was developed to provide an online compilation of transfer parameters in the form of equilibrium-based whole-organism to media concentration ratios. The database contains information from more than 500 publications, more than 1400 species and a hundred thousand CRwo-media values.

Radiation-induced Endothelial Inflammation is Transferred via Secretome to Recipient Cells in a STAT-Driven Process

Jos
Irradiation is the most common treatment of cancer. However, minimizing the normal tissue injury, especially the damage to vascular endothelium, still remains a challenge. This study aimed to analyze direct and indirect radiation effects by investigating mechanisms of signal transfer from irradiated to non-irradiated endothelial cells by means of secreted proteins. It is known that human coronary artery endothelial cells (HCAECest2) undergo radiation-induced senescence 14 days post-exposure to 10 Gy X-rays. Proteomics analysis was performed...

Brain Damage in 90 Day-old Rats Exposed During the Entire Gestation to Co-90 Gamma Rays or Cf-252 Neutrons At Different Dose Rates

Michael Gruenberger
Purpose: To determine the effect of dose rate and relative biological efficiency of neutron vs gamma irradiation for protracted, in utero exposure Status: 1989 - 1992, terminated Treatment: Protracted Co-60 gamma irradiation and Cf-252 neutrons plus gamma (ratio 2/1) irradiation at different dose rates delivered over the entire gestation Dosimetry: Gamma: ionization chamber; neutrons: ionization chamber filled with circulating tissue-equivalent gas Endpoints: Early and late effects on brain weight and late effects on brain histology...

Thyroid diseases near Semipalatinsk Nuclear Test Site - Data

Bernd Grosche
A description of the study is given in STOREDB:STUDY1008 (http://dx.doi.org/doi:10.20348/STOREDB/1108) . The data stored here include all the EXCEL and SPSS system files that were relevant for preparing the data used for Grosche et al., 2017 (http://www.storedb.org/store_v3/download.jsp?fileId=11331) . The steps taken for data preparation are described in http://www.storedb.org/store_v3/download.jsp?fileId=11333, the codebook is given in http://www.storedb.org/store_v3/download.jsp?fileId=11334. The original data set, including information of all 1,287 examinations which were carried out among 1,067 study participants is available in...

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