1,131 Works

Educational Program Evaluation Model, From the Perspective of the New Theories

Soleiman Ahmady, Maryam Akbari Lakeh, Simin Esmaeilpoor, Malihe Arab & Minoo Yaghmaei
Introduction: This study is focused on common theories that influenced the history of program evaluation and introduce the educational program evaluation proposal format based on the updated theory. Methods: Literature searches were carried out in March-December 2010 with a combination of key words, MeSH terms and other free text terms as suitable for the purpose. A comprehensive search strategy was developed to search Medline by the PubMed interface, ERIC (Education Resources Information Center) and the...

Cardiac Rhabdomyoma In Familial Tuberous Sclerosis

Amit Kumar Chaurasia, S Harikrishnan, S Bijulal, Dinesh Choudhary & Tharakan JA
Cardiac rhabdomyomas are often associated with tuberous sclerosis in infants. We report a 5 month old child presented with a tumor in the right ventricle and echocardiography features of rhabdomyoma. Both the child and her father had cutaneous features of tuberous sclerosis. In the absence of features of congestive heart failure, surgery is rarely required.

Determinants of Nurses’ Caring Behaviors (DNCB): Preliminary Validation of a Scale

Saleh Salimi & Afsaneh Azimpour
Introduction: Nurses’ Caring behaviors might be affected by many variables. The aim of this study was to develop and test a valid and reliable questionnaire to specify these determinants. Methods: Both qualitative and quantitative methods were applied to develop the questionnaire. The development process of the instrument was conducted in three phases. The first phase consisted of four steps: in-depth interviews, development of the preliminary version of the 38- item DNCB, expert panel review, and...

Health-Related Quality of Life and its Predictive Factors among Infertile Women

Sekineh Mohammad Alizadeh Charandabi, Mahin Kamalifard, Mehrzad Mahzad Sedaghiani, Ali Montazeri & Elham Dehghanpour Mohammadian
Introduction: The present study aimed to determine health-related quality of life (HRQOL) and its predictive factors among infertile women. Methods: This cross-sectional study was conducted on infertile women referring to Majidi Infertility Center (Tabriz, Iran). The data was collected through self-administered questionnaires including clinical and demographic characteristics and the Persian version of 36-item short form health survey (SF-36). One-sample t-test, independent t-test, one-way analysis of va-riance (ANOVA), and logistic regression were used for data analysis....

Should a Double-Lumen Catheter be withdrawn?

Samad Shams Vahdati
Introduction: Haemodialysis needs a credible and recurrent access to the systemic circula-tion which can be accomplished by way of central vein catheterization. We report the case of bleeding after withdrawal of the double lumen catheter. Case Presentation: A 36-year-old woman who was a known case of end-stage renal disease referred to a dialysis center because of her arteriovenous fistula malfunction. A double-lumen catheter was inserted via the right internal jugular vein but failed to become...

Effects of Preoperative Non-Steroidal Anti-Inflammatory Drugs on Pain Mitigation and Patients’ Shoulder Performance Following Rotator Cuff Repair

Alireza Rouhani, Ali Tabrizi, Asghar Elmi, Naghi Abedini & Fardin Mirza Tolouei
Purpose: Pain is one of the most important factors adversely affecting clinical outcomes of operated patients. The present study aims at evaluating effects of preoperative COX2 non-steroidal anti-inflammatory inhibitors on pain mitigation and performance of patients with shoulder rotator cuff tear. Methods: This case-control study was conducted on 60 patients suffering from rotator cuff injury candidate for arthroscopic repair. The patients were classified in two parallel and matched groups. One group (case group) was treated...

Effect of gap distance on tensile strength of preceramic base metal solder joints

Milad Motamedi & Farnaz Fattahi
Background and aims. In order to fabricate prostheses with high accuracy and durability, soldering techniques have been introduced to clinical dentistry. However, these prostheses always fail at their solder joints. The purpose of this study was to evaluate the effect of gap distance on the tensile strength of base metal solder joints. Materials and methods. Based on ADA/ISO 9693 specifications for tensile test, 40 specimens were fabricated from a Ni-Cr alloy and cut at the...

Analgesic Activity of Some 1,2,4-Triazole Heterocycles Clubbed with Pyrazole, Tetrazole, Isoxazole and Pyrimidine

Shantaram Gajanan Khanage, Appala Raju, Popat Baban Mohite & Ramdas Bhanudas Pandhare
Purpose: In the present study in vivo analgesic activity of some previously synthesized 1,2,4-triazole derivatives containing pyrazole, tetrazole, isoxazole and pyrimidine ring have been evaluated. Methods: Acetic acid induced writhing method and Hot plate method has been described to study analgesic activity of some 1,2,4-triazole derivatives containing pyrazole, tetrazole, isoxazole and pyrimidine as a pharmacological active lead. Results: Thirty six different derivatives containing 1,2,4-triazole ring were subjected to study their in vivo analgesic activity. Chloro,...

Skin Infection Management Using Novel Antibacterial Agents

Ramin Mohammadzadeh & Nejla Ahmadiyan
Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA) cause difficulties in the management of skin and soft tissue infections and have led to morbidity and mortality in hospital-acquired infections especially in susceptible individuals, those who are generally sick or immunosuppressed. Currently approaches in antibacterial agents offer opportunities to manage the trouble using novel anti-infection systems. Therefore, nanotechnology, a most promising field for generating new applications in medicine, has introduced a most prominent nanoproduct named as nanosilver...

Phytochemical Screening and Antimicrobial Properties of a Common Brand of Black Tea (Camellia sinensis) Found in Nigerian Environment

Olosunde Funmilayo, Abu-Saeed Kamaldeen & Abu-Saeed Muhammad Buhari
Purpose: The chemical compositions of Camellia sinensis is not completely known but is understood to be quite complex. Black tea is more complex than green tea partly because of the oxidation process that occurs during fermentation. C. sinensis has been used for different purposes. This study is aimed at determining chemical constituents and antimicrobial activities of a common brand of black tea (Lipton®) in Nigeria. Methods: Standard methods were employed for testing carbohydrates, tannins, saponins,...

Synthesis, Characterization and Antimicrobial Activity of Certain Novel Aryl Hydrazone Pyrazoline-5-Ones Containing Thiazole Moiety

Maliki Reddy Dastagiri Reddy, Aluru Raghavendra Guru Prasad, Yadati Narasimha Spoorthy & Lakshmana Rao Krishna Rao Ravindranath
Purpose: The aim of this article is to synthesize, characterize and evaluate the antimicrobial activity of certain novel 3-methyl-5-oxo-4-(phenyl hydrazono)-4,5-dihydro-pyrazol-1-yl]-acetic acid N|-(4-substituted thiazol-2-yl)-hydrazides. Methods: The synthesized compounds were characterized by elemental analysis and IR, NMR and mass spectral data. The antimicrobial activity of novel compounds was evaluated by broth dilution method. Results: XVe, XVf and XVg have shown better antibacterial activity than other compounds of the series. XVa, XVc, XVd and XVe have shown better...

How to Select a Journal to Submit and Publish Your Biomedical Paper?

Farhad Shokraneh, Roghayeh Ilghami, Rasoul Masoomi & Alireza Amanollahi
Introduction: selection of journal for publication purpose is one of concerns of biomedical researchers. They apply various criteria to choose appropriate journal. Here, we have tried to collect main criteria biomedical researchers use to select a journal to submit their work. Methods: we collected these criteria through focus group conversations with researchers during our careers, feedbacks from participants of our scientific writing workshops and non-systematic reviewing of some related literature. Results: we have presented a...

Lysosomal Storage Diseases: Heterogeneous Group of Disorders

David A. Wenger, Paola Luzi & Mohammad A. Rafi
The name of lysosomal storage diseases stems from the fact that in this category of disorders specific undegraded materials are stored in the lysosomes. This is usually caused by a lysosomal enzyme deficiency and leads to a cascade of pathological outcomes. Apart from deficiency of lysosomal enzymes, lysosomal storage diseases also include deficiencies in proteins necessary for enzyme functioning, proteins needed for post-translational modification of these enzymes and proteins required for export of certain compounds...

Anthropometric Indices Added the Predictive Ability of Iron Status in Prognosis of Atherosclerosis

Motahar Heidari-Beni, Mehrangiz Ebrahimi-Mameghani, Masoud Hajimaghsood & Mohammad Asghari Jafarabadi
Background: Abnormal homeostasis of iron such as deficiency or overload is associated with the pathogenesis of cardiovascular disease (CVD). Another risk factor for CVD is obesity whose added predictive ability to iron status has been assessed by few study. This study aimed to eva¬luate the effect of adding anthropometric indices to a model based on iron status as risk factors of CVD. Methods: This cross-sectional study included 140 adult women aged 18-50 years randomly se¬lected...

Derivative Spectrophotometric Method for Estimation of Antiretroviral Drugs in Fixed Dose Combinations

P.B. Mohite, R.B. Pandhare & S.G. Khanage
Purpose: Lamivudine is cytosine and zidovudine is cytidine and is used as an antiretroviral agents. Both drugs are available in tablet dosage forms with a dose of 150 mg for LAM and 300 mg ZID respectively. Method: The method employed is based on first order derivative spectroscopy. Wavelengths 279 nm and 300 nm were selected for the estimation of the Lamovudine and Zidovudine respectively by taking the first order derivative spectra. The conc. of both...

Oreganum vulgare Linn. leaf: An Extensive Pharmacognostical and Phytochemical Quality Assessment

Veni Bharti & Neeru Vasudeva
Purpose: Standardization and detailed pharmacognostical studies of Oreganum vulgare Linn. leaf for authentication and commercial utilization. Methods: Oreganum vulgare Linn. leaf was with standardization according to standard procedures described in WHO, 2011 and I.P. 1996. Results: The physicochemical parameters total ash, acid insoluble ash, water soluble ash and sulphated ash were found to be 11.5%, 11%, 5, 10.5% w/w respectively. Foaming index was found be <100. The trace elements were found to be copper, lead,...

HPLC-Analysis of Polyphenolic Compounds in Gardenia jasminoides and Determination of Antioxidant Activity by Using Free Radical Scavenging Assays

Riaz Uddin, Moni Rani Saha, Nusrat Subhan, Hemayet Hossain, Ismet Ara Jahan, Raushanara Akter & Ashraful Alam
Purpose: Gardenia jasminoides is a traditional medicinal plant rich in anti-inflammatory flavonoids and phenolic compounds and used for the treatment of inflammatory diseases and pain. In this present study, antioxidant potential of Gardenia jasminoides leaves extract was evaluated by using various antioxidant assays. Methods: Various antioxidant assays such as 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay, reducing power and total antioxidant capacity expressed as equivalent to ascorbic acid were employed. Moreover, phenolic compounds were detected by...

Genotype, allele and haplotype frequencies of four TCL1A gene polymorphisms associated with musculoskeletal toxicity in the South Indian descent

Umamaheswaran Gurusamy, Steven Aibor Dkhar, Arun Kumar Annan Sudarsan, Srinivasa Rao Katiboina, Kadambari Dharanipragada & Adithan Chandrasekaran
Introduction: Decline in circulating estrogen levels cause lessening of bone mass accompanied with musculoskeletal pain, which is the primary cause for treatment discontinuation in patients taking aromatase inhibitors. Evidence from the recent genome-wide association studies (GWAS) suggests that the genetic variability underlying TCL1A gene will increase the risk of aromatase inhibitors (AIs) - induced musculoskeletal toxicity. Currently, no data is available on the frequency distribution of TCL1A gene polymorphisms in Indians. Methods: In this pilot...

Role of phosphor and GAS-6 in inflammation in hemodialysis patients in Tabriz, Iran

Jamal Halaj Zadeh, Amir Ghorbanihaghjo, Hassan Argani, Shahnam Valizadeh, Najat Halaj, Amirmansour Vatankhah, Hakimeh Rezaei Aghdam & Siavoush Dastmalchi
BACKGROUND: Inflammation is recognized in up to 50% of chronic kidney disease (CKD) patients, being a common feature of advanced renal disease and crucial mediator of vascular calcification which may be relevant in CKD. This study was aimed at evaluating the role of Growth arrest–specific 6 (Plasma GAS-6) and mineral metabolism abnormalities in hemodialysis patients. METHODS: We enrolled a total of 92 adults including 46 (28 males and 18 females) clinically stable hemodialysis patients (HD)...

Effect of Citrate Phosphate Dextrose Solution on Reperfusion Injury in Coronary Artery Bypass Surgical Patients Undergoing Cardiopulmonary Bypass

Alireza Yaghoubi, Saeid Danaee, Shahin Imani, Mohammadali Sheikhalizadeh & Morteza Ghojazadeh
Introduction: Reperfusion injury is one of the most common phenomena associated with coronary artery bypass graft (CABG) .The mechanism of ischemia and reperfusion injury is not known precisely, but may be free radicals and other activated oxygen metabolites have an important role in tissue damage following reperfusion injury. This study was to evaluation of citrate solution effects on oxidative stress and cardiac function and Cardiac enzymes in patient's candidate to CABG. Methods: In Double blind...

The impact of demographic characteristics on fatigue and mental disorders among 12-hour petrochemical shift workers

Ahmad Bazazan, Yahya Rasoulzadeh, Iman Dianat, Abdolrasoul Safaiyan, Zohreh Mombeini & Ehsan Shiravand
Background: Shift workers may be exposed to fatigue and mental disorders due to various work-related risk factors. This study evaluated the impact of demographic characteristics on fatigue and mental disorders among 12-hour shift workers in petrochemical industries. Methods: This study was conducted among 290 shift workers of Pardis Petro­chemical Company in Iran. Data were collected using a general questionnaire for the demographic characteristic as well as multidimensional fatigue inventory (MFI-20) and general health questionnaire (GHQ-28)....

Apical Hypertrophic Cardiomyopathy in Association with PulmonaryArtery Hypertension

Mehdi Peighambari, Mozghan Parsaei, Anita Sadeghpour & Azin Alizadehasl
Apical Hypertrophic Cardiomyopathy is an uncommon condition constituting 1% -2% of the cases with Hypertrophic Cardiomyopathy (HCM) diagnosis. We interestingly report two patients with apical hypertrophic cardiomyopathy in association with significant pulmonary artery hypertension without any other underlying reason for pulmonary hypertension. The patients were assessed by echocardiography, cardiac catheterization and pulmonary function parameters study.

Evaluation of the effect of CaCl2 and alginate concentrations and hardening time on the characteristics of Lactobacillus acidophilus loaded alginate beads using response surface analysis

Farzaneh Lotfipour, Shahla Mirzaeei & Maryam Maghsoodi
Purpose: This article describes preparation and characterization of beads of alginate containing probiotic bacteria of Lactobacillus acidophilus DMSZ20079. Methods: Fourteen formulations using different alginate (ALG) and CaCl2 concentrations as well as hardening times were prepared using extrusion technique. The prepared beads were characterized in terms of size, morphology, encapsulation efficiency and bacterial viabilities in acid (pH 1.8, 2 hours) condition. Results: The results showed that spherical beads with narrow size distribution ranging from 1.32±0.04 to...

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