17,166 Works

Theory of Magnetic Methods of Applied Geophysics with an Application to the San Andreas Fault

Joshua Lawrence Soske
The attempts of geological and mining engineers to decipher the structure of the outermost formations of the earth's crust have led to many comprehensive studies, which now stand as monuments to their efforts. Their studies, in general, are confined almost exclusively to systematic collection, description, and analysis of facts which they were able to obtain by immediate observation at accessible points on and near the surface of the earth. These observations have many times been...

GFPnovo2, a brighter GFP variant for in vivo labeling in C. elegans

Ardalan Hendi & Kota Mizumoto
Green fluorescent protein (GFP) is one of the most common fluorophores used to label cells and proteins in C. elegans. Previous artificial protein evolution strategy has generated a variant of eGFP, GFPnovo2, which is 3.3 times brighter than the original eGFP in the DT40 cell line (Arakawa et al, 2008). GFPnovo2 carries four mutations from the original eGFP (Y145F, V163A, S202T, L221V), and has the same excitation/emission wavelengths as the original eGFP. Here we compared...

K2 Candidates Table

NASA Exoplanet Archive
The K2 candidates table lists objects from the published literature identified as candidates or false positives. If objects are confirmed as planets, their status in this table is updated but the objects remain.

A Unified Strategy to Ent-Kauranoid Natural Products: Total Syntheses of (-)-Maoecrystal Z, (-)-Trichorabdal A, and (-)-Longikaurin E

John Thomas Schafer Yeoman
The diterpenoid constituents of the Isodon plants have attracted reasearchers interested in both their chemical structures and biological properties for more than a half-century. In recent years, the isolations of new members displaying previously unprecedented ring systems and highly selective biological properties have piqued interest from the synthetic community in this class of natural products. Reported herein is the first total synthesis of such a recently isolated diterpenoid, (–)-maoecrystal Z. The principal transformations implemented in...

Some effects of a chrysin bromide-derivative on GABA-A receptors and on Caenorhabditis elegans

José L Téllez-Arreola, Alejandro Valdez-Calderón, Simplicio González-Montiel, Ataúlfo Martinez-Torres & Adan Hernandez

AllWISE Source Catalog

Wright, Edward L.; Eisenhardt, Peter R. M.; Mainzer, Amy K.; Ressler, Michael E.; Cutri, Roc M.; Jarrett, Thomas; Kirkpatrick, J. Davy; Padgett, Deborah; McMillan, Robert S.; Skrutskie, Michael; Stanford, S. A.; Cohen, Martin; Walker, Russell G.; Mather, John C.; Leisawitz, David; Gautier, Thomas N., III; McLean, Ian; Benford, Dominic; Lonsdale, Carol J.; Blain, Andrew; Mendez, Bryan; Irace, William R.; Duval, Valerie; Liu, Fengchuan; Royer, Don; Heinrichsen, Ingolf; Howard, Joan; Shannon, Mark; Kendall, Martha; Walsh, Amy L.; Larsen, Mark; Cardon, Joel G.; Schick, Scott; Schwalm, Mark; Abid, Mohamed; Fabinsky, Beth; Naes, Larry; Tsai, ChaoWei
The AllWISE program builds upon the work of the successful Wide-field Infrared Survey Explorer mission (WISE; Wright et al. 2010) by combining data from the WISE cryogenic and NEOWISE (Mainzer et al. 2011 ApJ, 731, 53) post-cryogenic survey phases to form the most comprehensive view of the full mid-infrared sky currently available. The AllWISE Source Catalog contains accurate positions, apparent motion measurements, four-band (3.4, 4.6, 12, 22 microns) fluxes and flux variability statistics for over...

Slender-Body Hypervelocity Boundary-Layer Instability

Nicholaus J. Parziale
With novel application of optical techniques, the slender-body hypervelocity boundary-layer instability is characterized in the previously unexplored regime where thermo-chemical effects are important. Narrowband disturbances (500-3000~kHz) are measured in boundary layers with edge velocities of up to 5~km/s at two points along the generator of a 5 degree half angle cone. Experimental amplification factor spectra are presented. Linear stability and PSE analysis is performed, with fair prediction of the frequency content of the disturbances; however,...

Terahertz and Microwave Spectroscopy of Liquids and Hydrogen-Bonded Clusters

Ian Alan Finneran
The microwave (MW, 0.3-100 GHz) and terahertz (THz, 0.1-10 THz) regions of the electromagnetic spectrum are replete with a rich set of molecular motions, including soft inter- and intramolecular vibrations, torsions, and rotations. At room temperature these motions are well populated, and play an active role in condensed-phase chemistry on Earth. This work details the development of one MW and two THz spectrometers along with their application to the study of liquids and hydrogen-bonded clusters....

The Absorption Coefficient of Hard Gamma-Rays

Chung-Yao Chao
The relation between the frequency of hard radiations and the absorption co-efficient is not experimentally well established at the present time. In the following work the absorption coefficient of γ-rays of ThC" is carefully investigated owing to their homogeneity. As a result, the observed absorption coefficient of light elements is found to agree fairly well with the theoretical formula of Klein and Nishina. Running from low to high atomic numbers, the absorption per electron is,...

daf-2 regeneration of mechanosensory neurons: integration

Zehra C Abay, Michelle Yu-Ying Wong & Brent Neumann
We previously established that a critical event for axonal fusion to occur is the exposure of PS ‘save-me’ signals after injury (Neumann et al., 2015), which increase with advancing age (Abay et al., 2017a). To determine if daf-2 is involved in this age-dependent modulation of PS exposure, we visualised and quantified the level of PS exposed after PLM axotomy using a secreted, tagged version of Annexin V (Neumann et al., 2015; Mapes et al., 2012)....

Materials Experiment and Analysis Database:

Edwin Soedarmadji, John Gregoire & Contributors

Membrane Potential Dynamics of Hippocampal Neurons During Ripples in Awake Mice

Bradley Kline Hulse
During periods of slow wave sleep and quiet wakefulness, the hippocampal formation generates spontaneous population bursts that are organized as a high-frequency “ripple” oscillation. The neurons that participate in these bursts often replay previously experienced activity patterns encoded during alert behavior, and interfering with ripple generation produces deficits in learning and memory tasks. For these reasons, ripples play a prominent role in theories of memory consolidation and retrieval. While spiking during ripples has been extensively...

Flashover of Insulation in Homogenous Electric Fields

George K. Surrapas Diamos & William Abbett Lewis
No Abstract.

Materials Experiment and Analysis Database:

Edwin Soedarmadji, John Gregoire & Contributors

Electromechanical Properties of 3D Multifunctional Nano-Architected Materials

Max Louis Lifson
In this thesis, we explore the fabrication and characterization of 3D architected multifunctional materials in three different categories: varied density for tailored mechanical response, stiff ultra low-k dielectric materials, and direct laser writing of piezoelectric structures at the micron scale. The density of an architected material plays a large role in determining its effective Young’s modulus, strength, and deformation behavior. The first section of this work explores the effect of incorporating two density regions into...

Mutations in KCNQ potassium channels cause pharyngeal pumping defects in C. elegans

Yoanne Clovis, Alexis Webb, Carl Turner & Bill Roberts
Pumps were stimulated with 10mM 5HT in M9 recorded as electropharyngeograms (EPGs) for 2 minutes in a NemaMetrix ScreenChip, and analyzed using NemAnalysis software (NemaMetrix). The null mutant strains kqt-1(aw3) and kqt-3 (aw1) were kindly donated by Dr. Aguan Wei (Wei et al., 2002) A) Pump frequency in kqt-1(aw3) animals was significantly lower than in N2s, while kqt-3(aw1) worms showed an increase in pump frequency (*p<0.05; ***p<0.01; 1-tailed Mann-Whitney U-test; n = 21-23 worms in...

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