38,144 Works

Dissecting abdominal aortic aneurysm in Ang II-infused mice: suprarenal branch ruptures and apparent luminal dilatation.

Patrick Segers, Alain Tedgui, Carole Van Der Donckt, Peter Modregger, Nikolaos Stergiopulos, Alessandra Piersigilli, Alberto Astolfo, Marco F M Stampanoni, Bram Trachet, Jessica Sordet-Dessimoz & Rodrigo A Fraga-Silva
AIMS In this work, we provide novel insight into the morphology of dissecting abdominal aortic aneurysms in angiotensin II-infused mice. We demonstrate why they exhibit a large variation in shape and, unlike their human counterparts, are located suprarenally rather than infrarenally. METHODS AND RESULTS We combined synchrotron-based, ultra-high resolution ex vivo imaging (phase contrast X-Ray tomographic microscopy) with in vivo imaging (high-frequency ultrasound and contrast-enhanced micro-CT) and image-guided histology. In all mice, we observed a...

ESTOUT: Stata module to export estimation results from estimates table

Ben Jann
estout produces a table of regression results from one or several models for use with spreadsheets, LaTeX, HTML, or a word-processor table. eststo stores a quick copy of the active estimation results for later tabulation. esttab is a wrapper for estout. It displays a pretty looking publication-style regression table without much typing. estadd adds additional results to the e()-returns for one or several models previously fitted and stored. This package subsumes the previously circulated esto,...

Statistical testing against baseline was common in dental research

Padhraig S Fleming, Nikolaos Pandis, Arun Madahar & Despina Koletsi
OBJECTIVES To assess the presence of within-group comparisons with baseline in a subset of leading dental journals and to explore possible associations with a range of study characteristics including journal and study design. STUDY DESIGN AND SETTING Thirty consecutive issues of five leading dental journals were electronically searched. The conduct and reporting of statistical analysis in respect of comparisons against baseline or otherwise along with the manner of interpretation of the results were assessed. Descriptive...

OSL-thermochronometry of feldspar from the KTB borehole, Germany

M Kook, C Ankjærgaard, P G Valla, E J Rhodes, F Herman, G E King, F Preusser, B Guralnik, A S Murray, R Chen, M Jain & S E Lowick
The reconstruction of thermal histories of rocks (thermochronometry) is a fundamental tool both in Earth science and in geological exploration. However, few methods are currently capable of resolving the low-temperature thermal evolution of the upper ∼2 km of the Earth's crust. Here we introduce a new thermochronometer based on the infrared stimulated luminescence (IRSL) from feldspar, and validate the extrapolation of its response to artificial radiation and heat in the laboratory to natural environmental conditions....

Aortic valve replacement and concomitant procedures with the Perceval valve: results of European trials.

François Laborde, Steffen Pfeiffer, Axel Haverich, Willem J Flameng, Bart Meuris, Thierry Carrel, Thierry A Folliguet, Matthias Bechtel, Theodor Fischlein & Malakh Shrestha
BACKGROUND The Perceval (Sorin Group, Milan, Italy) is a self-anchoring sutureless aortic valve prosthesis. We report the short- to midterm results of combined aortic valve replacement (AVR) with concomitant procedures in elderly patients undergoing operation as part of 3 consecutive prospective multicenter European studies. METHODS From April 2007 to February 2013, 243 patients (mean age, 79.7 ± 5.1 years; female patients, 61%; median EuroSCORE, 9%) underwent AVR with concomitant procedures. The concomitant procedures were coronary...

Health risk appraisal in older people 3: prevalence, impact, and context of pain and their implications for GPs

Steve Iliffe, Gerhard Gillmann, Kalpa Kharicha, Andreas E Stuck, Cameron Swift, Danielle Harari & Claudia Carmaciu
BACKGROUND: Pain is a common experience in later life. There is conflicting evidence of the prevalence, impact, and context of pain in older people. GPs are criticised for underestimating and under-treating pain. AIM: To assess the extent to which older people experience pain, and to explore relationships between self-reported pain and functional ability and depression. DESIGN OF STUDY: Secondary analysis of baseline data from a randomised controlled trial of health risk appraisal. SETTING: A total...

Clinical and microbiological results following nonsurgical periodontal therapy with or without local administration of piperacillin/tazobactam

Marc Lauenstein, G. Rutger Persson & Marion Kaufmann
OBJECTIVES We assessed if adjunct administration of piperacillin/tazobactam added clinical and microbiological treatment benefits. MATERIALS AND METHODS Thirty-six subjects (mean age 52.1 years (SD ± 10.3)) (NS by group) with chronic periodontitis were randomly enrolled receiving subgingival debridement and the local administration of piperacillin/tazobactam (test group) or debridement alone (control group). Bleeding on probing (BOP), probing pocket depth (PPD), and microbiological counts of 74 species were studied by checkerboard DNA-DNA hybridization up to month 6 after treatment....

Migration Matters in South Asia: Commonalities and Critiques

Karin Astrid Siegmann, Susan Thieme, Sanjay Barbora, Vineetha Menon & Ganesh Gurung

Laparoscopic versus open end colostomy closure: a single-center experience

Dino Kröll, Melika Umer, Daniel Inderbitzin, Beat Schnüriger, Daniel Candinas & Peter Studer
The aim of this study was to review our experience with laparoscopic end colostomy closure. A retrospective review of a prospectively entered database was performed. Proportions and continuous variables were compared using the Fisher's exact and the Mann-Whitney U tests, respectively. Within the study period, 53 patients underwent closure of end colostomies. The main reasons for the colonic resections were perforated diverticulitis (52.7%) and neoplasms (20.8%). In 28 patients (53%), laparoscopic closure (LC) was attempted....

Feasibility, Safety and Outcome of Recanalisation Treatment in Childhood Stroke.

Joel Fluss, Claudia Poloni, Annette Hackenberg, Jan Gralla, Oliver Maier, Johannes Weber, Corrado Angelo Bernasconi, Marcel Arnold, Sandra Bigi, Andrea Sara Dulcey, Urs Fischer, Amber Tamsin Melliger, Maja Steinlin, Alexandre N Datta & Johannes Kaesmacher
Objective Intravenous thrombolysis and endovascular therapy (IVT/EVT) are evidence-based treatments for adults with arterial ischemic stroke (AIS). However, randomized controlled trials in pediatric patients are lacking. This study aimed to describe feasibility, safety, and outcome of IVT/EVT in children with AIS. Methods Retrospective study (01/2000-12/2015) of a multicenter, population-based consecutive cohort of patients aged 1 month - 16 years diagnosed with AIS presenting with a pedNIHSS ≥4. Clinical and radiological data of patients receiving IVT/EVT...

Population effectiveness of opportunistic chlamydia testing in primary care in Australia: a cluster-randomised controlled trial.

Meredith Temple-Smith, Sabine Braat, Basil Donovan, Christopher K Fairley, David Regan, Matthew Law, Jane S Hocking, John Kaldor, Rebecca Guy, Alaina Vaisey, Jane Gunn, Liliana Bulfone & Nicola Low
BACKGROUND Screening young adults who are sexually active for genital Chlamydia trachomatis infection is promoted in several high-income countries, but its effectiveness at the population level is highly debated. We aimed to investigate the effects of opportunistic chlamydia testing in primary care on the estimated chlamydia prevalence in the population aged 16-29 years in Australia. METHODS We did a cluster-randomised controlled trial. Clusters were rural towns with a minimum of 500 women and men aged...

Mobile Cloud Networking: Mobile Network, Compute, and Storage as One Service On-Demand

Thomas Bohnert, Almerima Jamakovic & Georgios Karagiannis
The Future Communication Architecture for Mobile Cloud Services: Mobile Cloud Networking (MCN) is a EU FP7 Large-scale Integrating Project (IP) funded by the European Commission. MCN project was launched in November 2012 for the period of 36 month. In total top-tier 19 partners from industry and academia commit to jointly establish the vision of Mobile Cloud Networking, to develop a fully cloud-based mobile communication and application platform.

Hi Prof! Interview mit Dr. Elena Hubschmid und Prof.em. Dr. Norbert Thom von Marcus Moser.

Norbert Thom & Elena Hubschmid
Sie gelten als anspruchsvoll, pflegen einen formlosen Kommunikationsstil und wollen Spass im Job: Wer nach 1980 geboren wurde, gehört zur Generation Y und lebt im Bewusstsein, dank der demografischen Entwicklung am Arbeitsmarkt immer wichtiger zu werden. UniPress hat eine Angehörige der Generation Y sowie einen Babyboomer zum generationsübergreifenden Gespräch eingeladen.

Strain-induced coupling of electrical polarization and structural defects in SrMnO₃ films

Morgan Trassin, Ingo P. Krug, Laura Maurel, Eric Langenberg, Martin Lilienblum, Ulrich Johannes Aschauer, Javier Blasco, Carsten Becher, Manfred Fiebig, Dennis Meier, Nicola A. Spaldin, Pedro A. Algarabel, José A. Pardo & César Magén

Prevalence, genetic diversity and antimicrobial susceptibility of Listeria monocytogenes isolated from open-air food markets in Greece

Anders Johansson, George Filiousis, Joachim Frey & Vincent Perreten
A total of 210 food samples originating from milk products, ready-to-eat salads, raw meat and raw meat products purchased in ten open-air market places in Thessaloniki, Greece, were analyzed for the presence of Listeria monocytogenes. Thirty (14.3%) contained L. monocytogenes with the highest prevalence in raw meat (27.5%), raw meat products (18%) and cheese (8%). The strains were susceptible to 16 antimicrobials as determined by microbroth dilution, except one strain which displayed resistance to tetracycline...

Neonatal Outcomes of Very Low Birth Weight and Very Preterm Neonates: An International Comparison.

Satoshi Kusuda, Shoo K Lee, Dirk Bassler, Josep Figueras-Aloy, Brian Reichman, Gunnar Sjörs, Junmin Yang, Kei Lui, Neena Modi, Laura San Feliciano, Brian A Darlow, INeo International Network For Evaluating Outcomes Of Neonates, Mark Adams, Prakesh S Shah, Lucia Mirea, Stellan Håkansson & Rintaro Mori
OBJECTIVE To compare rates of a composite outcome of mortality or major morbidity in very-preterm/very low birth weight infants between 8 members of the International Network for Evaluating Outcomes. STUDY DESIGN We included 58 004 infants born weighing <1500 g at 24(0)-31(6) weeks' gestation from databases in Australia/New Zealand, Canada, Israel, Japan, Spain, Sweden, Switzerland, and the United Kingdom. We compared a composite outcome (mortality or any of grade ≥3 peri-intraventricular hemorrhage, periventricular echodensity/echolucency, bronchopulmonary dysplasia,...

Color polymorphism and intrasexual competition in assemblages of cichlid fish

Charlotte Hemelrijk, Ton G.G. Groothuis, Ole Seehausen & Peter D. Dijkstra
The origin and maintenance of phenotypic polymorphisms is a classical problem in evolutionary ecology. Aggressive male-male competition can be a source of negative frequency-dependent selection stabilizing phenotypic polymorphisms when aggression is biased toward the own morph. We studied experimental assemblages of red and blue color morphs of the Lake Victoria cichlid fish Pundamilia. Aggression was investigated in mixed-color and single-color assemblages. We found that aggression was indeed biased toward males of the same color, which...

Management of cervical premalignant lesions.

Katayoun Taghavi, Smita Joshi, Sushma Mogri, Shang-Ying Hu & Partha Basu
Treatment of cervical premalignant lesions (cervical intraepithelial neoplasia; CIN) of different grades is very effective, simple, and safe. The entire transformation zone of the cervix needs to be treated either by an ablative technique (cryotherapy or thermal ablation) or an excisional technique (large loop excision of transformation zone or cold knife conization); the choice of treatment depends on the size and location of the lesion and the type of the transformation zone. The cure rate...

Veridicality of self-concept of strengths in male adolescents

Achim Conzelmann, Mirko Schmidt & Stefan Valkanover
Changes in physical self-concept and veridicality (i.e., the appropriateness of one’s self-perceptions to reality) during childhood and adolescence are related to performance in physical fi tness, exercise, and global self-esteem, particularly in male adolescents. This cross-sectional study examined the relation between the self-concept of strength and actual strength in groups of male adolescents ages 12 to 15 years. For this purpose, 889 male adolescents (M age = 13.2 yr., SD = 1.0) were questioned about...

Impaired cortical energy metabolism but not major antioxidant defenses in experimental bacterial meningitis.

Stephen Leib, Marco Ghielmetti, Stephan Christen, Hao Ren & Martin G. Täuber
The loss of soluble brain antioxidants and protective effects of radical scavengers implicate reactive oxygen species in cortical neuronal injury caused by bacterial meningitis. However, the lack of significant oxidative damage in cortex [J. Neuropathol. Exp. Neurol. 61 (2002) 605-613] suggests that cortical neuronal injury may not be due to excessive parenchymal oxidant production. To see whether this tissue region exhibits a prooxidant state in bacterial meningitis, we examined the state of the major cortical...

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