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Additional file 8: Figure S2. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
The distribution of first nucleotide bias (A) and the nucleotide bias at each position (B) of the novel miRNAs in the four libraries. (A) Each color in the figure showed the miRNA tags whose first base was a certain base. Height of bar was proportional to the frequency of the corresponding base at the given length from 20 to 23 nt. (B) Each color in the figure showed the miRNA tags whose certain base was a...

Additional file 8: of Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara ChiurchiÚ, Elin Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti & Paolo Rossi
Table of included paediatric studies. (DOR, diagnostic odds ratio; LR+, positive likelihood ratio; LR-, negative likelihood ratio; PCT, procalcitonin; SIRS, systemic inflammatory response syndrome; MC, Microbiologically confirmation; CR Chart Review). (PDF 19 kb)

Additional file 7: of Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara ChiurchiÚ, Elin Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti & Paolo Rossi
Representation in the ROC space of studies in EOS. Representation in the ROC space of studies on PCT for diagnosis of EOS. (ROC, receiver operating characteristic). (PDF 157 kb)

Additional file 7: Table S6. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
The matching results of sRNAs among non-coding RNAs in the four libraries by Rfam search. (DOC 31 kb)

Additional file 6: Table S5. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
The matching results of sRNAs among non-coding RNAs in the four libraries by Genbank search. (DOC 30 kb)

Additional file 6: of Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara ChiurchiÚ, Elin Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti & Paolo Rossi
Forest plot and summary statistics of studies on PCT for diagnosis of EOS. The forest plot represents in each study the sensitivity and the specificity of PCT, together with the 95% CI for diagnosis of EOS. (CI, confidence interval; FP, false positive; FN, false negative; PCT, procalcitonin; TP, true positive; TN, true negative). (PDF 323 kb)

Additional file 5: of Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara ChiurchiÚ, Elin Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti & Paolo Rossi
Representation in the ROC space of neonatal studies divided in EOS and LOS. Representation in the ROC space of studies on PCT for diagnosis of sepsis in neonatal age, divided by cut-off subgroup and EOS/LOS. (ROC, receiver operating characteristic). (PDF 46 kb)

Additional file 5: Table S4. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
The statistics of types and total number of repetitive sequence of the sRNAs in the four libraries. (DOC 69 kb)

Additional file 4: of Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara ChiurchiÚ, Elin Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti & Paolo Rossi
Forest plot of studies on PCT for diagnosis of sepsis in neonatal age. The forest plot represents in each study the sensitivity and the specificity of PCT, together with the 95% CI for diagnosis of sepsis in neonatal age stratified according cut-off subgroup. (CI, confidence interval; FP, false positive; FN, false negative; PCT, procalcitonin; TP, true positive; TN, true negative). (PDF 743 kb)

Additional file 4:Figure S1. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
Length distribution of the unique sRNA sequences in the four libraries. RCK and YACK: ROC22 and YA05-179 under sterile water stress after 48 h, respectively; RT and YAT: ROC22 and YA05-179 under Sporisorium scitamineum stress after 48 h, respectively. (TIF 35 kb)

Additional file 3: of Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara ChiurchiÚ, Elin Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti & Paolo Rossi
Table of included neonatal studies. CR, Chart review; DOR, diagnostic odds ratio; LR +, positive likelihood ratio; LR -, negative likelihood ratio; MC, Microbiologically confirmation; PCT, procalcitonin; SIRS, systemic inflammatory response syndrome; MC (Microbiologically confirmation). (PDF 130 kb)

Additional file 3: Table S3. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
The filtering results of high-through sequencing data in the four libraries. (DOC 40 kb)

Additional file 2: of Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara ChiurchiÚ, Elin Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti & Paolo Rossi
Table of bias. Table of bias of neonatal and paediatric studies according to QUADAS-2. (PDF 84 kb)

Additional file 2: Table S2. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
The primers of qRT-PCR performed to validate 23 selected miRNA target genes. (DOC 41 kb)

Additional file 1: of Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara ChiurchiÚ, Elin Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti & Paolo Rossi
Search strategy. (PDF 54 kb)

Additional file 20: Table S16. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
KEGG analysis of predicted target genes of novel miRNAs in YAT/YACK. (DOC 58 kb)

Additional file 11: of Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara ChiurchiÚ, Elin Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti & Paolo Rossi
Representation in the ROC space of studies in LOS and paediatric sepsis. Representation in the ROC space of studies on PCT for diagnosis in LOS and paediatric sepsis. (PDF 154 kb)

Additional file 1: Table S1. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
The forward primers of qRT-PCR performed to validate the 20 selected differentially expressed miRNAs. (DOCX 20 kb)

Additional file 10: of Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara ChiurchiÚ, Elin Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti & Paolo Rossi
Forest plot and summary statistics of studies on PCT for diagnosis of LOS and paediatric sepsis. The forest plot represents in each study the sensitivity and the specificity of PCT, together with the 95% CI for diagnosis of LOS and paediatric sepsis. (CI, confidence interval; FP, false positive; FN, false negative; PCT, procalcitonin; TP, true positive; TN, true negative). (PDF 337 kb)

Additional file 19: Table S15. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
KEGG analysis of predicted target genes of novel miRNAs in RT/RCK. (DOC 57 kb)

Additional file 18: Table S14. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
KEGG analysis of predicted target genes of known miRNAs in YAT/YACK. (DOC 34 kb)

Effectiveness of an individual, online e-learning program about sexually transmitted infections: a prospective cohort study

Linda Bos-Bonnie, Jan Van Bergen, Ellen Te Pas, Michael Kijser & Nynke Van Dijk
Abstract Background Primary health-care professionals play an important role in the treatment and prevention of Sexually Transmitted Infections (STI). Continuing Medical Education (CME)-courses can influence the knowledge and behavior of health-care professionals concerning STI. We performed a prospective cohort study to evaluate if the individual and online e-learning program “The STI-consultation”, which uses the Commitment-to-Change (CtC)-method, is able to improve the knowledge, attitude and behavior of Dutch General Practitioners (GPs), concerning the STI-consultation. This e-learning...

Additional file 17: Table S13. of Small RNA sequencing reveals a role for sugarcane miRNAs and their targets in response to Sporisorium scitamineum infection

Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo & Youxiong Que
KEGG analysis of predicted target genes of known miRNAs in RT/RCK. (DOC 58 kb)

Additional file 2: of Effectiveness of an individual, online e-learning program about sexually transmitted infections: a prospective cohort study

Linda Bos-Bonnie, Jan Van Bergen, Ellen Te Pas, Michael Kijser & Nynke Van Dijk
English-language version of the questionnaire used in the study (translated from Dutch). This file contains the English-language version of the questionnaire used in the study. The content of this file was translated from the original questionnaire used in our study. (DOC 27 kb)

Additional file 1: of Effectiveness of an individual, online e-learning program about sexually transmitted infections: a prospective cohort study

Linda Bos-Bonnie, Jan Van Bergen, Ellen Te Pas, Michael Kijser & Nynke Van Dijk
Learning objectives for the e-learning program “The STI-consultation”, presented per competence-area (translated from Dutch). This file contains the learning objectives for the e-learning program “The STI-consultation”, presented per competence-area. The content of this file was based on the “Program plan e-learning “The STI-consultation” (Programmaplan PIN “Het soa-consult”). (DOCX 23 kb)

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