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Additional file 2: Figure S2. of Long noncoding RNA expression profiles in sub-lethal heat-treated hepatoma carcinoma cells

Qingsong Deng, Shihan Chen, Chunchuan Fu, Jiayun Jiang, Mengda Zou, Yunhua Tan, Xiaofei Wang, Feng Xia, Kai Feng, Kuansheng Ma & Ping Bie
cRNA amplification and labeling procedures (TIF 251 kb)

Additional file 1: Figure S1. of Long noncoding RNA expression profiles in sub-lethal heat-treated hepatoma carcinoma cells

Qingsong Deng, Shihan Chen, Chunchuan Fu, Jiayun Jiang, Mengda Zou, Yunhua Tan, Xiaofei Wang, Feng Xia, Kai Feng, Kuansheng Ma & Ping Bie
RNA quality. ① and ⑧: DL2000 Marker; ②: Normal cultured HCC cells(The first repeat experiment); ③: sub-lethally heat-treated HCC cells(The first repeat experiment); ④Normal cultured HCC cells(The second repeat experiment); ⑤sub-lethally heat-treated HCC cells(The second repeat experiment); ⑥Normal cultured HCC cells(The third repeat experiment); ⑦ sub-lethally heat-treated HCC cells(The third repeat experiment); (TIF 1244 kb)

Additional file 3: Figure S3. of Minocycline modulates NFÎşB phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells

Alberto Guerra, Warren Rose, Peiman Hematti & W. Kao
Showing colony forming abilities of SA after 6 hours of coculture with media controls, MSCs with or without anti-IL-6, and MSCs pretreated with minocycline with or without anti-IL-6. (JPG 146 kb)

Additional file 2: Figure S2. of Minocycline modulates NFÎşB phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells

Alberto Guerra, Warren Rose, Peiman Hematti & W. Kao
Showing expression of IL6 in MSCs when cultured alone or with SA with and without minocycline pretreatment. (JPG 171 kb)

Additional file 1: Figure S1. of Minocycline modulates NFÎşB phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells

Alberto Guerra, Warren Rose, Peiman Hematti & W. Kao
Showing proliferation of MSCs after 24 hours of minocycline treatment in a dose-dependent manner. (JPG 103 kb)

Additional file 2: Figure S2. of Staphylococcus aureus Prostatic abscess: a clinical case report and a review of the literature

David Carroll, Ian Marr, G Khai Lin Huang, Deborah Holt, Steven Tong & Craig Boutlis
CT of pelvis showing persistence of prostatic abscess in the left lobe of the prostate. (PNG 447 kb)

Additional file 5: Figure S2. of An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions

Nicola Senior, Kalesh Sasidharan, Richard Saint, Andrew Scott, Mitali Sarkar-Tyson, Philip Ireland, Helen Bullifent, Z. Rong Yang, Karen Moore, Petra Oyston, Timothy Atkins, Helen Atkins, Orkun Soyer & Richard Titball
Analysis of gene essentiality using the genome-scale model and 2 million randomly generated media (using available exchange reactions in the model). The x-axis list the number of genes identified as essential in a set of media (y-axis). (TIFF 95 kb)

MOESM1 of Estimating the cost-effectiveness of daclatasvir + sofosbuvir versus sofosbuvir + ribavirin for patients with genotype 3 hepatitis C virus

Phil McEwan, Samantha Webster, Thomas Ward, Michael Brenner, Anupama Kalsekar & Yong Yuan
Additional file 1: Figure S1. Schematic of the cohort-based Markov simulation model.

Additional file 1: Figure S1. of Staphylococcus aureus Prostatic abscess: a clinical case report and a review of the literature

David Carroll, Ian Marr, G Khai Lin Huang, Deborah Holt, Steven Tong & Craig Boutlis
CT of pelvis showing prostatic abscess in the left lobe of the prostate. (PNG 477 kb)

Additional file 4: Figure S1. of An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions

Nicola Senior, Kalesh Sasidharan, Richard Saint, Andrew Scott, Mitali Sarkar-Tyson, Philip Ireland, Helen Bullifent, Z. Rong Yang, Karen Moore, Petra Oyston, Timothy Atkins, Helen Atkins, Orkun Soyer & Richard Titball
Analysis of gene essentiality using the genome-scale model and 2 million randomly generated media. A. Number of essential genes (blue bars; y-axis) predicted by the model using a specific random media composition derived from the available exchange reactions in the model (x-axis). The overlap with experimentally identified genes in BAB broth media is shown as well (red bars). B. Number of essential genes (y-axis) predicted by the model using a specific media composition that is...

Additional file 1: Figure S1. of Evaluation of left atrial volume and function using single-beat real-time three-dimensional echocardiography in atrial fibrillation patients

Qian Zhang, Ju-Fang Wang, Qing-Qing Dong, Qing Yan, Xiang-Hong Luo, Xue-Ying Wu, Jian Liu & Ya-Ping Sun
The short axis of the left ventricle, apical four-chamber, three-chamber, and short-axis images. (TIFF 689 kb)

Additional file 8: of Estimation of linkage disequilibrium and effective population size in New Zealand sheep using three different methods to create genetic maps

Vincent Prieur, Shannon Clarke, Luiz Brito, John McEwan, Michael Lee, Rudiger Brauning, Ken Dodds & BenoĂŽt Auvray
LD decay over genetic distances and evolution of N e over time estimated using the three methods in CompRCP sheep. The LD curve for the CompRCP breed is similar to those observed for Comprcp2, but present a higher LD at short distances and a relatively high N e after 15 generations. Knowing the breed composition of CompRCP, the results are consistent with what would be expected; i.e. a lower LD at short distances but very...

Additional file 7: of Estimation of linkage disequilibrium and effective population size in New Zealand sheep using three different methods to create genetic maps

Vincent Prieur, Shannon Clarke, Luiz Brito, John McEwan, Michael Lee, Rudiger Brauning, Ken Dodds & BenoĂŽt Auvray
LD decay over genetic distances and evolution of N e over time estimated using the three methods in Comprcp2 sheep. At short distances, the Comprcp2 sheep gave the lowest LD (0.06) and, at 15 generations ago, the highest estimate of N e of the breed groups studied. This could be due to this population being derived from different genetically distant breed groups such as Romney, Coopworth and Perendale but also Dorset and Suffolk. The tests...

Additional file 6: of Estimation of linkage disequilibrium and effective population size in New Zealand sheep using three different methods to create genetic maps

Vincent Prieur, Shannon Clarke, Luiz Brito, John McEwan, Michael Lee, Rudiger Brauning, Ken Dodds & BenoĂŽt Auvray
Average number of marker pairs available for N e estimation, per generation. The hyperbolic nature of the equation used to define the relationship between genetic distances between markers and number of generations in the past explains the fast decrease of the number of marker pairs available per generation. (TIFF 119 kb)

Additional file 2: Figure S2. of Spatial and temporal patterns of diarrhoea in Bhutan 2003â 2013

Kinley Wangdi & Archie Clements
Spatial distribution of the posterior means of random effects for diarrhoea in Bhutan in Model III. (a) Spatially unstructured random effects (b) structured random effects. (TIFF 2610 kb)

Additional file 2: of MicroRNA profiling of ovarian granulosa cell tumours reveals novel diagnostic and prognostic markers

Wei-Tzu Cheng, Roseanne Rosario, Anita Muthukaruppan, Michelle Wilson, Kathryn Payne, Peter Fong, Andrew Shelling & Cherie Blenkiron
Density distribution of p values between adult-GCT and juvenile-GCT tumours in the miRNA microarray dataset. The red and grey lines represent the p value density distributions for the true GCT groups in the miRNA dataset and for the 100 permuted and resampled groups, respectively. (TIFF 48 kb)

Additional file 1: Figure S1. of Spatial and temporal patterns of diarrhoea in Bhutan 2003â 2013

Kinley Wangdi & Archie Clements
Spatial distribution of the posterior means of structured random effects for diarrhoea in Bhutan in Model II. (TIFF 2238 kb)

Additional file 2: of Estimation of linkage disequilibrium and effective population size in New Zealand sheep using three different methods to create genetic maps

Vincent Prieur, Shannon Clarke, Luiz Brito, John McEwan, Michael Lee, Rudiger Brauning, Ken Dodds & BenoĂŽt Auvray
Workflow Summary. Description of the processes established to perform quality control and data analysis. The workflow per breed leads to the analysis of the three methods tested in this paper to calculate LD and N e within breed. The workflow applied to the full data set allowed us to estimate the genetic distances between breed. This will allow investigation of signatures of selection in the sheep genome using local Fst, LD and N e across...

Additional file 1: Figure S1. of The excretory-secretory products of Echinococcus granulosus protoscoleces directly regulate the differentiation of B10, B17 and Th17 cells

Wei Pan, Wen-Ting Hao, Yu-Juan Shen, Xiang-Yang Li, Yan-Juan Wang, Fen-Fen Sun, Jian-Hai Yin, Jing Zhang, Ren-Xian Tang, Jian-Ping Cao & Kui-Yang Zheng
The effects of PSC somatic antigens on the induction of IL-10 and IL-17A expression in B and CD4+ T cells. a and b present the relative expression of IL-10 and IL-17A in cultured B cells, respectively; c shows the relative expression of IL-17A in CD4+ T cells. The differences were analyzed using one-way ANOVA. Asterisks indicate statistically significant differences between groups. *P 

Additional file 3 of Ultrasonography and dual-energy computed tomography provide different quantification of urate burden in gout: results from a cross-sectional study

Tristan Pascart, Agathe Grandjean, Laurène Norberciak, Vincent Ducoulombier, Marguerite Motte, Hélène Luraschi, Marie Vandecandelaere, Catherine Godart, Eric Houvenagel, Nasser Namane & Jean-François Budzik
Tophus of the first metatarsophalangeal joint (A) detected by ultrasonography but (B) not seen with dual energy computed tomography. (TIF 2781 kb)

Additional file 2 of Ultrasonography and dual-energy computed tomography provide different quantification of urate burden in gout: results from a cross-sectional study

Tristan Pascart, Agathe Grandjean, Laurène Norberciak, Vincent Ducoulombier, Marguerite Motte, Hélène Luraschi, Marie Vandecandelaere, Catherine Godart, Eric Houvenagel, Nasser Namane & Jean-François Budzik
Bean-shaped tophus of the first metatarsophalangeal joint seen in (A) ultrasonography, (B) 3D dual-energy computed tomography (DECT) imaging and (C) 2D DECT imaging. For DECT images, urate appears in green and calcium in blue. (TIF 2889 kb)

Additional file 1: of Ultrasonography and dual-energy computed tomography provide different quantification of urate burden in gout: results from a cross-sectional study

Tristan Pascart, Agathe Grandjean, Laurène Norberciak, Vincent Ducoulombier, Marguerite Motte, Hélène Luraschi, Marie Vandecandelaere, Catherine Godart, Eric Houvenagel, Nasser Namane & Jean-François Budzik
Tophus with large posterior acoustic shadow. (TIF 1894 kb)

A comparison of broad-scale model estimates with independent bird data from East-Africa

Martin Jung, Neil Burgess & Tim Newbold
Poster for SCCS 2016 conference in Cambridge.

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