1,165 Works

Probabilistic cytoarchitectonic map of LB (Amygdala) (v8.2)

O. Kedo, K. Zilles, N. Palomero-Gallagher, S. Bludau & K. Amunts
This dataset contains the distinct architectonic LB (Amygdala) in the individual, single subject template of the MNI Colin 27 as well as the MNI ICBM 152 2009c nonlinear asymmetric reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to...

Phosphodiesterase 2A, 4 and 10A contribution in the integration of dopamine signals in mice striatal D1 and D2 medium-sized spiny neurones

E. Mota, S. Bompierre, L. R. V. Castro & P. Vincent
Dopamine signals are transduced by D1 and D2 dopamine receptors which trigger mirror effects through the cAMP/PKA signalling cascade in D1 and D2 medium-sized spiny neurones (MSNs). Phosphodiesterases (PDEs), which determine the profile of cAMP signals, are highly expressed in MSNs, but their respective roles in dopamine signal integration remain poorly understood. We used genetically-encoded FRET biosensors to monitor at the single cell level the functional contribution of PDE2A, PDE4 and PDE10A in the changes...

Anterograde visualization of projections from lateral orbitofrontal cortex in rat (case: F35)

H. Kondo, G.M. Olsen, M. Gianatti, B. Monterotti, T. Sakshaug & M.P. Witter
High-resolution bright-field microscopy images (43) of serial coronal brain sections showing anterogradely labeled axons in orbitofrontal cortex (OFC) in a female adult Sprague Dawley rat. The anterograde tracer biotinylated dextran amine (BDA) was injected into the lateral orbitofrontal cortex (LOC). Brain sections are 300 µm apart and 50 µm thick. The dataset contains a complete series throughout the anterior-posterior extent of the brain, contributing to visualization of a topographically organized connectivity from OFC throughout the...

Individual Brain Charting: ARCHI emotional

A. Pinho, A. Amadon, T. Ruest, M. Fabre, E. Dohmatob, I. Denghien, C. Ginisty, S. Becuwe-Desmidt, S. Roger, L. Laurier, V. Joly-Testault, G. Médiouni-Cloarec, C. Doublé, B. Martins, P. Pinel, E. Eger, G. Varoquaux, C. Pallier, S. Dehaene, L. Hertz-Pannier & B. Thirion
This dataset contains functional magnetic resonance images (fMRIs) of 12 subjects that investigates cognitive-emotional processes on perception of faces and expressions. The paradigm was arranged in blocks that comprised sets of trials. Two categories of conditions can be highlighted from the paradigm: (1) the face-task category and (2) the eye-task category. Both categories involved self-reply according to the stimulus presented at every condition. The face-task category consisted in the presentation of human faces, whereas the...

Co-activation based parcellation of the human intraparietal sulcus

E. C. Cieslik-Köchling, V. I. Müller, C. Grefkes, A. R. Laird, P. T. Fox & S. B. Eickhoff
It is known that the intraparietal sulcus (IPS) can be subdivided into different modules based on their cytoarchitectonic organization. We here used co-activation based parcellation to identify distinct functional submodules within human bilateral IPS based on their task-based co-activation profile across neuroimaging studies. That is, left and right IPS, were used as seed regions and for all voxels in these regions of interest the co-activation profile across neuroimaging experiments reported in the Brainmap Database was...

Recordings of spiking activity and local field potentials from Human Visual Cortex V3

M. W. Self, P. R. Roelfsema, J. K. Possel, J. C. Peters, J. Reithler, R. Goebel, P. Ris, D. Jeurissen, L. Reddy, S. Claus & J. C. Baayen
The first quantitative description of spiking actvity from area V3 of human visual cortex. We recorded electrophyisological data from two micro-wires implanted chrnoically in area V3 of an epileptic patient. The data has been filtered into spiking actvity and local field potential. Data from several different visual tasks are presented. The data show very clear receptive-fields, in both spiking and gamma frequencies. The tuning curves (orientation, contrast, spatial frequency, size) resemble those from macaque monkeys....

Response profiles to uni- and bilateral stimulation in higher-order visual cortex

J. Reithler, J. Peters & R. Goebel
We used functional Magnetic Resonance Imaging (fMRI) at 7T, complemented with additional 3T data. Six healthy participants, with normal or corrected to normal vision, saw stimuli of two different object classes (presented in blocks) while performing a visual detection task. Whereas fixation was kept at the middle of the screen, stimuli were presented at peripheral locations (at 6° eccentricity in the lower visual quadrant). Crucially, a stimulus could either be presented in isolation in one...

TMS-EEG perturbation in patients with disorders of consciousness

F. Raimondo, A. Wolff, L. Sanz, A. Barra, H. Cassol, M. Carrière, S. Laureys & O. Gosseries
Patients with disorders of consciousness (DOC) are awake but are unable to communicate and report upon their level of awareness. While standardized behavioral evaluation has been the most reliable clinical tool to diagnose DOC, neuroimaging and electrophysiology have proven to be techniques that can provide complementary information to the behavioral assessment. This multimodal dataset contains data from DOC patients, including structural magnetic resonance imaging, resting state high-density electroencephalography, electroencephalography during stimulation with transcranial magnetic pulses...

Probabilistic cytoarchitectonic map of Area hIP3 (IPS) (v9.0)

F. Scheperjans, K. Hermann, S. B. Eickhoff, K. Amunts, A. Schleicher, L. Hoemke, H. Mohlberg & K. Zilles
This dataset contains the distinct architectonic Area hIP3 (IPS) in the individual, single subject template of the MNI Colin 27 as well as the MNI ICBM 152 2009c nonlinear asymmetric reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped...

Probabilistic cytoarchitectonic map of Area FG3 (FusG) (v6.0)

S. Lorenz, K. Weiner, J. Caspers, H. Mohlberg, A. Schleicher, S. Bludau, S. B. Eickhoff, K. Grill-Spector, K. Zilles & K. Amunts
This dataset contains the distinct probabilistic cytoarchitectonic map of Area FG3 (FusG) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the...

Hippocampal image volume derived from Thy1-GFP-M transgenic mouse

F. Pavone & L. Silvestri
Reconstruction of the hippocampus of a Thy1-GFP-M transgenic mouse, where a subset of pyramidal neurons and of interneurons are labeled. Data obtained with serial two-photon tomography.

3-D point data representing the spatial distribution of corticopontine projections originating in the mouse visual cortex

M. Ovsthus, SC Yates, N Groeneboom, M. Puchades, J.G. Bjaalie & T.B. Leergaard
The 3-D point coordinate data represent the spatial distribution of mouse brain subcortical projections from different parts of the visual cortex to the caudoputamen, thalamus, superior colliculus and pontine nuclei. The point data are derived from segmented images series programmatically downloaded from the Allen Brain Atlas Data Portal. The data are suited for 3-D visualization and comparison the spatial arrangement of visual corticostriatal, corticothalamic, corticocollicular, and corticopontine projections.

Densities and 3D distributions of synapses using FIB/SEM imaging in the mouse neocortex (somatosensory cortex)

M. Turegano, R. Rodriguez, J. DeFelipe & A. Merchan-Perez
Synapses have been identified, segmented and quantified in the adult mouse somatosensory cortex with 3D electron microscopy (FIB-SEM). Three animals have been used (ID5, ID24 and ID25). The six layers of the somatosensory cortex have been studied. Data obtained include the number of asymmetric and symmetric synapses, their sizes and their spatial distribution.

Density measurements of different receptors for CA3 (Hippocampus) [rat, v2.0]

N. Palomero-Gallagher & K. Zilles
This dataset contains the densities (in fmol/mg protein) of receptors for classical neurotransmitters of CA3 (hippocampus) obtained by means of quantitative _in vitro_ autoradiography. The receptor densities are visualized as _fingerprints_ (**fp**), which provide the mean density and standard deviation for each of the analyzed receptor types, averaged across samples. Overview of available measurements [ **receptor** \| **_neurotransmitter_** \| _labeling agent_ ]: **AMPA** \| **_glutamate_** \| _[3H]AMPA_ **kainate** \| **_glutamate_** \| _[3H]kainate_ **NMDA** \| **_glutamate_**...

Probabilistic cytoarchitectonic map of HATA (Hippocampus) (v11.1)

K. Amunts, O. Kedo, M. Kindler, P. Pieperhoff, H. Mohlberg, N. J. Shah, U. Habel, F. Schneider & K. Zilles
This dataset contains the distinct architectonic HATA (Hippocampus) in the individual, single subject template of the MNI Colin 27 as well as the MNI ICBM 152 2009c nonlinear asymmetric reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to...

Probabilistic cytoarchitectonic map of Area TE 2.1 (STG) (v5.1)

D. Zachlod, P. Morosan, S. Bludau, H. Mohlberg, K. Zilles & K. Amunts
This dataset contains the distinct architectonic Area TE 2.1 (STG) in the individual, single subject template of the MNI Colin 27 as well as the MNI ICBM 152 2009c nonlinear asymmetric reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then...

Distribution and density of Complex basket formations in the human cerebral cortex

L. Blazquez-Llorca, V. García-Marín & J. DeFelipe
This dataset contains the density of VGAT-ir Complex basket formations (Cbk-formations) in various cytoarchitectonic areas of the human cerebral cortex. Cell density was analyzed on cell-body-stained histological sections of 5 human postmortem brains that were supplied by Dr R. Alcaraz, Forensic Pathology Service, Basque Institute of Legal Medicine, Bilbao, Spain.

Probability map of bundle lh_CAC-PrCu_0 (atlas of superficial white matter fibre bundles, version 2018)

M. Guevara, C. Román, J. Houenou, D. Duclap, C. Poupon, J. F. Mangin & P. Guevara
This data contains the probability map of a short fibre bundle connecting the left hemisphere Caudal Anterior Cingulate and Precuneus regions of the Desikan-Killiany atlas, in the MNI ICBM152 reference brain. This bundle was identified using a hybrid approach, incorporating anatomical information (from cortical regions of interest) and fibre shape (fibre clustering), from the tractography datasets of 78 subjects in the Neurospin’s ARCHI database. The map shows the probability of finding a fibre belonging to...

Probability map of bundle rh_PrC-SP_0 (atlas of superficial white matter fibre bundles, version 2018)

M. Guevara, C. Román, J. Houenou, D. Duclap, C. Poupon, J. F. Mangin & P. Guevara
This data contains the probability map of a short fibre bundle connecting the right hemisphere Precentral and Superior Parietal regions of the Desikan-Killiany atlas, in the MNI ICBM152 reference brain. This bundle was identified using a hybrid approach, incorporating anatomical information (from cortical regions of interest) and fibre shape (fibre clustering), from the tractography datasets of 78 subjects in the Neurospin’s ARCHI database. The map shows the probability of finding a fibre belonging to the...

3D cyto- and receptor architectonic map of macaque primary motor area F2d

L. Rapan, S. Froudist-Walsh, M. Niu, T. Funck, K. Zilles & N. Palomero-Gallagher
A multimodal analysis of the macaque motor cortex was carried out to create a 3D atlas integrating and reconciling discrepancies between previously published maps. This involved a quantitative and statistically testable approach to the analysis of cytoarchitecture in the macaque monkey frontal agranular cortex, in combination with an in vitro quantitative receptor autoradiographic analysis of the regional and laminar distribution patterns of 13 different neurotransmitter receptors. The borders of the identified areas were traced onto...

Density measurements of different receptors for dorsal part of Area hOc2 (V2, 18) [human, v1.0]

N. Palomero-Gallagher & K. Zilles
This dataset contains the densities (in fmol/mg protein) of receptors for classical neurotransmitters in the dorsal part of Area hOc2 (V2, 18) obtained by means of quantitative _in vitro_ autoradiography. The receptor densities are visualized as _fingerprints_ (**fp**), which provide the mean density and standard deviation for each of the analyzed receptor types, averaged across samples. Overview of available measurements [ **receptor** \| **_neurotransmitter_** \| _labeling agent_ ]: **AMPA** \| **_glutamate_** \| _[3H]AMPA_ **kainate** \|...

CCEP database of the Medical Informatics Platform

O. David, A. Jegou, A. Boyer, M. Jedynak, V. Tuyisenge, C. Saubat-Guigui, R. Zouglech, B. Chanteloup-Foret, C. Benar, A. Trebuchon, F. Bartolomei, A. Schulze-Bonhage, S. Rheims, S. Francione, L. Minotti & P. Kahane
Single-pulse direct electrical stimulation of cortical regions in patients suffering from focal drug-resistant epilepsy who are explored using intracranial electrodes induces electrophysiological responses. Such cortico-cortical evoked potentials (CCEP) can be used to infer functional and anatomical brain connectivity. This pseudonymized database in BIDS-iEEG format contains stereotactic EEG data obtained in implanted epileptic patients who were candidates to resective surgery and undergone intracortical stimulations. The data were collected from a multicenter population of 217 patients. This...

Probability map of bundle rh_SM-Ins_0 (atlas of superficial white matter fibre bundles, version 2018)

M. Guevara, C. Román, J. Houenou, D. Duclap, C. Poupon, J. F. Mangin & P. Guevara
This data contains the probability map of a short fibre bundle connecting the right hemisphere Supramarginal and Insula regions of the Desikan-Killiany atlas, in the MNI ICBM152 reference brain. This bundle was identified using a hybrid approach, incorporating anatomical information (from cortical regions of interest) and fibre shape (fibre clustering), from the tractography datasets of 78 subjects in the Neurospin’s ARCHI database. The map shows the probability of finding a fibre belonging to the bundle...

Distribution of dopamine 2 receptor positive neurons in the adolescent female mouse brain

E.R. Cullity, I.E. Bjerke, K. Kjelsberg, K.M. Charan, T.B. Leergaard & J.H. Kim
High-resolution bright-field microscopy images of coronal brain sections showing dopamine 2 receptor positive neurons across the adolescent (35 days old) mouse brain. The dataset consists of an image series covering the rostral part of the brain from Drd2-EGFP mice. For each brain, every fourth section was processed by diaminobenzidine (DAB) immunohistochemistry using a polyclonal anti-GFP (RRID:AB_300798) antibody. The publication related to the dataset furthermore includes stereological counts of positive neurons in the prelimbic, infralimbic and...

Distribution of muscarinic acetylcholine receptors (type 2) in adult male C57Bl/J6 mice (coronal sections)

U. Schlegel, Martha Hvoslef-Eide, Kristian Lensjø & Marianne Fyhn
This dataset contains confocal image data of coronal sections following immunohistochemical staining for muscarinic acetylcholine receptor (type 2) – positive cells. These cells can facilitate the identification of the border between the primary visual cortex and the secondary visual cortex. According to Ji et al. (2015; “Modularity in the Organization of Mouse Primary Visual Cortex”, Neuron, 87, 632-643), layers IV and III in the primary visual cortex show very strong M2-expression levels, layers I, II...

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