Multiple samples are embedded in a single block to increase efficiency and increase reproducibility.
Used to assess bladder pressure associated with filling and emptying.
Used to assess spontaneous voiding in unrestrained mice.
A narrated video of mouse prostate lobe dissection.
Serial sections of mouse prostatic urethra in the transverse plane
Insight and Resources from a Study of the “Impact of Sex, Androgens, and Prostate Size on C57BL/6J Mouse Urinary Physiology”Chad Vezina
Men of advancing age are susceptible to prostate related urinary dysfunction but mechanisms are not fully known and factors that influence age of onset and severity of symptoms have not been determined. Mice are genetically tractable and are likely to play an important role in elucidating environmental, pharmacological , genetic, and aging-related mechanisms of urinary dysfunction. We and others have made significant strides in developing quantitative methods for assessing mouse urinary function. Yet, it remains...
Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulationChad Vezina
Antibody validation data for the manuscript titled: Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation
Introduction: We use mice to study male urinary dysfunction, including the role of environmental contaminants. However, little baseline data of mouse lower urinary tract exists. The goal of this study is to determine the impact of sex, androgens, and prostate size on gross morphology of mouse urinary tract and internal anatomy of the urethra. Methods: Androgens and prostate size were manipulated through exogenous testosterone supplementation, high dose finasteride (5-alpha-reductase inhibitor), and, in males, surgical castration...
We used Translating Ribosome Affinity Purification coupled with next generation sequencing (TRAP-seq) to profile mouse tubular epithelial cells during the course of injury and repair using the Kim-GCE mouse model. This novel mouse model allows lineage tracing of injured mouse tubular epithelial cells, which upregulate Kim1, and translational profiling by ribosomal pull down when crossed to the EGFP-L10a mouse. Transcriptional profiling was done at day 2, 7, and 14 after bilateral ischemia reperfusion injury.
Using adult mouse kidney, we compared single-cell RNA sequencing (scRNA-seq) data generated using the DropSeq platform with single-nucleus RNA sequencing (snRNA-seq) data generated using sNuc-DropSeq, DroNc-seq, and Chromium platforms. We validated snRNA-seq on fibrotic kidney from mice 14 days after unilateral ureteral obstruction (UUO) surgery. This dataset is related to the JASN paper titled "Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis." DOI:...
This instance is the same with MnM instance. However, for this instance, the MIP problem is solved by Cplex in python. Using data on "likes" from the Internet (e.g., epicurious.com), we create an objective function based on ideas from matrix completion (a Netflix competition), and then formulate a MIP problem whose objective is the sum of preferences of the roommates.
A photograph of Sherrill McCullough[?] practicing calligraphy, South Korea.
Collection of images detailing gene expression patterns in the human embryonic and fetal kidney
The name Wyndor and the production part of this problem is borrowed from a very popular OR textbook (Hillier and Lieberman (2012)). Our example extends the original Wyndor model to one in which the production plan is to be made while bearing in mind that the allocation of the advertising time slots affects sales of Wyndor products (two types of doors), and the final production plan will be guided by firm orders (sales) in the...
Daily Trojan, Vol. 123, No. 6, September 09, 1994.
Photograph of man holding egg, Southern California, 1927. "Subject: postmaster & egg; Client: Hollywood Playhouse; Year: 1927; Job: 4-6-15" -- on envelope.
Datasets generated and analyzed in Phipson et al. (2018) "Evaluation of variability in human kidney organoids", Nature Methods (In Press)
A group of students are standing and sitting outside with a missionary sister, holding their books.; The back of the postcard is blank and also contains the caption: "1088. - Union Sud-Africaine. Garçons et filles rivalisent d'application" ("Boys and girls compete for the application") There is also information about the printer: "Oeuvre de la Propagation de la Foi - Paris - 5, r. Monsieur-7e"
Children eating in the day nursery of the Société des missions évangéliques de Paris (Paris evangelical missionary society) in Bangwa. There is no child who are more than a year and half in the day nursery in the sixties.; Photograph published in the Journal des missions, January 1967.
Figures and data relating to the JASN 2018 paper titled "Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning"
To be provided
Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse KidneyAndrew McMahon
Figures and data relating to the JASN 2018 paper titled "Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney"
This is an instance from http://simopt.org/wiki/index.php?title=Multi-dimensional_Newsvendor_Problem. The example is adapted from the article Kim, S. (2006). Gradient-Based Simulation Optimization. Proceedings of the 2006 Winter Simulation Conference, 159-167. For this instance, we compare the performance of different stochastic algorithms: Stochastic Approximation(SA), Robust Stochastic Approximation(RSA) and Stochastic Decomposition(SD). To run the experiment of SA/RSA, please download the input file(model file for the subproblem) and the program files. Both algorithms run 10 replications, while all the parameters are...