502 Works

Ussing chamber pressure pump

Klaus Michel & Michael Schemann
These files are a description on how to build and program a high precision pressure pump to control tissue distension in Ussing chambers. In addition there is a video clip to show the ramp tissues distension

CLARITY and three-dimensional (3D) imaging of the mouse and porcine colonic innervation

Pu-Qing Yuan, Lixin Wang, Million Mulugeta & Yvette Tache
Regional ENS 3D structure/phenotype, axonal projections and connectivity in the mouse and pig colon.

Effect of intermittent hypoxia preconditioning in rats with chronic cervical spinal cord injury – An electrophysiological study

Gordon Mitchell, Elisa Gonzalez-Rothi, Latoya Allen, Marissa Ciesla, Arash Tadjalli & Alec Simon
Phrenic nerve, arterial blood pressure, and respiratory recordings for phrenic long term facilitation protocol.

Molecular phenotype distribution of single rat intracardiac neurons

Sirisha Achanta, Shaina Robbins, Alison Moss, Jonathan Gorky, Sean Nieves, Susan Tappan, Maci Heal, Clara Leung, Jin Chen, Zixi Cheng, James Schwaber & Rajanikanth Vadigepalli
Images collected from serial cryostat sectioning of a cryopreserved heart was used to reconstruct the 3D context. Transcriptional profiles taken from isolated single neurons and mapped back into the previously generated 3D context.

Electrophysiology in dog after subcutaneous nerve stimulation

Juyi Wan, Mu Chen, Yuan Yuan, Zhuo Wang, Changyu Shen, Michael Fishbein, Zhenhui Chen, Johnson Wong, Maria Grant, Thomas Everett & Peng-Sheng Chen
Antiarrhythmic and proarrhythmic effects of subcutaneous nerve stimulation in ambulatory dogs

opencor-py model

Hugh Sorby
Computes the cardiac myocyte action potential for the sympathetic drive input setting on the MAP-Core portal. Caption: Illustration of a whole body flatmap (centre) and central nervous system map (left) with a neural pathway highlighted.

Anatomy and histology of the domestic pig in the context of vagus nerve stimulation

Kip A Ludwig, Megan L Settell, Nicole A Pelot, Bruce E Knudsen, Aaron Dingle, Andrea L McConico, Evan N Nicolai, James K Trevathan, J Ashley Ezzell, Erika Ross, Kenneth J Gustafson, Andrew J Shoffstall, Justin C Williams, Weifeng Zeng, Samuel Poore, Luis Populin, Aaron Suminski & Warren M Grill
Incorporation of motor efferent branches of vagus into VNS activation

Mapping of ICN Neurons in a 3D Reconstructed Rat Heart

Clara Leung, Jin Chen, Alison Moss, Susan Tappan, Maci Heal, Todd Huffman, Navid Farahani, Leonard Eisenman, Zixi Cheng, Raj Vadigepalli & James Schwaber
Single intrinsic cardiac nervous system (ICN) neurons were marked in an image volume of heart sections that was anatomically delineated for the 3D reconstruction of the whole heart with mapped locations of individual ICN neurons.

Distribution of Nitregic Cholinergic and all MP Neurons

Dante Heredia
Contains source data and reconstructed images of nNOS, cholinergic and glial distribution in the murine large intestine.

Molecular Phenotype Distribution of Single Rat Intracardiac Neurons

Alison Moss, Clara Leung, James Schwaber, Jin Chen, Jonathan Gorky, Maci Heal, Rajanikanth Vadigepalli, Sean Nieves, Shaina Robbins, Sirisha Achanta, Susan Tappan & Zixi Cheng
Intracardiac neuron (ICN) samples were collected from a female rat heart using laser capture microdissection. We acquired transcriptomics data for 154 genes from the 151 samples we collected. Images of sampled neurons allow for 3D reconstruction of data.

SPARC Nerve Activity Predictor (SNAP)

Matthew P Ward
Interactive, AI-informed computational model of stimulus parameter-dependent vagal nerve responses resulting from bipolar, constant-current stimuli.

SPARC Nerve Activity Predictor (SNAP)

Matthew P Ward
Interactive, AI-informed computational model of stimulus parameter-dependent vagal nerve responses resulting from bipolar, constant-current stimuli.

Multi-scale human cardiac electrophysiology models

Colleen E. Clancy, Mao-Tsuen Jeng, Pei-Chi Yang & Timothy J. Lewis
A computational workflow for integration and implementation of a reusable and reproducible human cardiac multi-scale electrophysiology model. Caption: Illustration of ion channels and action potential propogation in cardiac tissue

2D Plot

Leah Reznikov
Interactive example for plotting gene expression using the RAW Graphs platform. Data are obtained from Prof. Leah Reznikov at University of Florida. Caption: Plot created using O2S2PARC platform with RAW Graphs

Quantified Morphology of the Human Vagus Nerve with Anti-Claudin-1

Nicole A Pelot, J Ashley Ezzell, Gabriel B Goldhagen, Jake E Cariello, Kara A Clissold & Warren M Grill
Quantified vagus nerve morphology across species

Quantified Morphology of the Rat Vagus Nerve

Nicole A. Pelot, Gabriel B. Goldhagen, Jake E. Cariello & Warren M. Grill
Binary traces from segmentation of cross sections of cervical and subdiaphragmatic rat vagus nerves stained with Masson's trichrome. Quantified effective nerve diameter, effective fascicle diameter, number of fascicles, and perineurium thickness.

Spatially tracked single-cell transcriptomics map of neuronal networks in the intrinsic cardiac nervous system

Raj Vadigepalli, James Schwaber, Shaina Robbins, Lakshmi Kuttippurathu, Sirisha Achanta, Alison Moss & Maci Heal
Spatially Tracked Single Neuron Anatomical and Molecular Profiling of the Pig Right Atrial Ganglionic Plexus

Neurofauna Rat

Ignacio Pascual
This detailed anatomical representation of a rat that can be viewed and explored in a 3D viewer.

Quantified Morphology of the Human Vagus Nerve with Anti-Claudin-1

Nicole A. Pelot, J. Ashley Ezzell, Gabriel B. Goldhagen, Jake E. Cariello, Kara A. Clissold & Warren M. Grill
Immunohistochemistry micrographs of human vagus nerves labeled with anti-claudin-1. Binary traces from segmentation to quantify effective nerve diameter, effective fascicle diameter, number of fascicles, and perineurium thickness.

Single cell RNA sequencing of retrogradely labeled mouse stellate ganglion neurons

Seoeun Lee, Vidhu Thaker & Lori Zeltser
Datasets from single cell sequencing of murine stellate ganglion neurons retrogradely labeled with cholera toxin B injections into the brown adipose tissue or forelimb

Expression of molecular markers in subpopulations of mouse celiac ganglion neurons

Seoeun Lee, Alexandre J Lafond & Lori Zeltser
Expression of molecular markers in subpopulations of mouse celiac ganglion neurons using small molecule FISH (RNAScope)

Generic pig colon scaffold

Mabelle Lin, Richard Christie & Peter Hunter
Annotated pig colon scaffold available for registration of segmented neural anatomical-functional mapping of enteric neural circuits.

Generic human lung scaffold

Arti Sukasem, Richard Christie & Peter Hunter
Annotated lung scaffold for human available for registration of segmented neural anatomical-functional mapping of pulmonary neural circuits.

Endorgan-specific Pseudorabies (PRV) infection in mouse kidney and liver

Clara Huesing, Heike Muenzberg, Andrei Derbenev, Andrea Zsombok, David Burk & Hayden Torres
Genetically-based neuro-modulation of adipose tissue functions

Imaging in vivo acetylcholine release in the peripheral nervous system with a fluorescent nanosensor in mice

Junfei Xia, Hongrong Yang, Michelle Mu, James Monaghan & Heather Clark
Development of ACh (acetylcholine) nanosensor that detects ACh release in real-time. This dataset includes in vitro, ex vivo, and in vivo experimental results.

Registration Year

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