88 Works

Submandibular ganglion stained by bungarotoxin and nanosensors in mouse

Junfei Xia, Hongrong Yang, Michelle Mu, Timothy Duerr, James Monaghan & Heather Clark
This data set describes staining of submandibular ganglion with a-bungarotoxin (BTX) and nanosensor developed by the Clark lab. BTX staining is used as a gold standard to validate the localization of nanosensor.

Influence of direct colon tissue electrical stimulation on colonic motility in anesthetized male Yucatan minipig

Muriel Larauche, Yushan Wang, Po-Min Wang, Genia Dubrovsky, Yi-Kai Lo, Ian Hsiang, James Dunn, Wentai Liu, Yvette Tache & Million Mulugeta
Direct proximal colon, transverse colon and colorectum wall electrical stimulation; monitor colon wall bio-impedance and colon manometry in all regions (proximal, transverse and distal) before, during and post stimulation.

Scientific Articles

Joost B Wagenaar & Leonardo A Guercio
A collection of relevant articles around Bioelectronic medicine, Biomarkers and digital health care

Comparison of the Intrinsic Cardiac Nervous System Across Male and Female Rat Hearts

Clara Leung, Shaina Robbins, Rajanikanth Vadigepalli, James Schwaber, Maci Heal, Susan Tappan, Todd Huffman, Navid Farahani & Zixi Cheng
Single neurons were mapped and cardiac anatomy was annotated in image volumes of male and female rat hearts to characterize the intrinsic cardiac nervous system between individuals and across sexes.

Molecular Phenotype Distribution of Single Rat Intracardiac Neurons

Sirisha Achanta, Shaina Robbins, Alison Moss, Jonathan Gorky, Sean Nieves, Susan Tappan, Maci Heal, Clara Leung, Jin Chen, Zixi Cheng, James Schwaber & Rajanikanth Vadigepalli
Images collected from serial cryostat sectioning of a cryopreserved heart was used to reconstruct the 3D context. Transcriptional profiles taken from isolated single neurons and mapped back into the previously generated 3D context.

Excitation Properties of Computational Models of Unmyelinated Peripheral Axons

Nicole A Pelot, David C Catherall, Brandon J Thio & Warren M Grill
Data and plotting code for excitation responses of multiple single compartment and multi-compartment models of peripheral unmyelinated axons

Selectivity of afferent microstimulation at the DRG using epineural and penetrating electrode arrays

Ameya Nanivadekar, Christopher Ayers, Max Novelli, Robert Gaunt, Doug Weber & Lee Fisher
This dataset contains over 50,000 instances of compound action potentials recorded in response to stimulation at the DRG via epineural and penetrating electrodes from nerve cuffs implanted on several distal branches of the sciatic and femoral nerve

Human Vagus Nerve Stained with Masson's Trichrome

Nicole A. Pelot, J. Ashley Ezzell, Gabriel B. Goldhagen, Eric Musselman, Jake E. Cariello, Kara A. Clissold & Warren M. Grill
Micrographs of cross sections of cervical and abdominal human vagus nerve stained with Masson's trichrome.

Mapping of ICN Neurons in a 3D Reconstructed Rat Heart

Clara Leung, Jin Chen, Alison Moss, Susan Tappan, Maci Heal, Todd Huffman, Navid Farahani, Leonard Eisenman, Zixi Cheng, Raj Vadigepalli & James Schwaber
Single intrinsic cardiac nervous system (ICN) neurons were marked in an image volume of heart sections that was anatomically delineated for the 3D reconstruction of the whole heart with mapped locations of individual ICN neurons.

Quantified Morphology of the Rat Vagus Nerve

Nicole A. Pelot, Gabriel B. Goldhagen, Jake E. Cariello & Warren M. Grill
Binary traces from segmentation of cross sections of cervical and subdiaphragmatic rat vagus nerves stained with Masson's trichrome. Quantified effective nerve diameter, effective fascicle diameter, number of fascicles, and perineurium thickness.

Quantified Morphology of the Human Vagus Nerve with Anti-Claudin-1

Nicole A Pelot, J Ashley Ezzell, Gabriel B Goldhagen, Jake E Cariello, Kara A Clissold & Warren M Grill
Quantified vagus nerve morphology across species

Quantified Morphology of the Human Vagus Nerve with Anti-Claudin-1

Nicole A. Pelot, J. Ashley Ezzell, Gabriel B. Goldhagen, Jake E. Cariello, Kara A. Clissold & Warren M. Grill
Immunohistochemistry micrographs of human vagus nerves labeled with anti-claudin-1. Binary traces from segmentation to quantify effective nerve diameter, effective fascicle diameter, number of fascicles, and perineurium thickness.

Neurofauna Rat

Ignacio Pascual
This detailed anatomical representation of a rat that can be viewed and explored in a 3D viewer.

Computational modelling of the mechanical behavior of the colon

Bhavesh Patel, Ghassan Kassab & Hans Gregersen
Contains data related to the computational simulation of the mechanical behavior of the colon.

Prototype simulation of undiseased human cardiac ventricular cells

Colleen Clancy & Pei-Chi Yang
A prototype use-case package consisting of a single-cell, 1D and 2D tissue model for simulation of autonomic effects on the cardiovascular system derived from the human ventricular model developed by O'Hara and Rudy group.

Phrenic nerve immunohistochemistry

Gordon Mitchell, Elisa Gonzalez-Rothi, Donald Bolser, Paul W Davenport, Latoya Allen, Marissa Ciesla, Yasin Seven, Arash Tadjalli, Alec Simon & Artem Svetlov
Immunohistochemistry of phrenic nerve afferents in acute intermittent hypoxia and hemisection injury conditioned rats

Morphometric analysis of the abdominal vagus nerve in rats

Leif Havton, Natalia Biscola, Warren M Grill, Nicole A Pelot, Terry Powley & Matthew Ward
Determination of light and electron microscopy characteristics of the abdominal vagus nerve in rats.

Ussing chamber pressure pump

Klaus Michel & Michael Schemann
These files are a description on how to build and program a high precision pressure pump to control tissue distension in Ussing chambers. In addition there is a video clip to show the ramp tissues distension

Effect of intermittent hypoxia preconditioning in rats with chronic cervical spinal cord injury – An electrophysiological study

Gordon Mitchell, Elisa Gonzalez-Rothi, Latoya Allen, Marissa Ciesla, Arash Tadjalli & Alec Simon
Phrenic nerve, arterial blood pressure, and respiratory recordings for phrenic long term facilitation protocol.

Molecular phenotype distribution of single rat intracardiac neurons

Sirisha Achanta, Shaina Robbins, Alison Moss, Jonathan Gorky, Sean Nieves, Susan Tappan, Maci Heal, Clara Leung, Jin Chen, Zixi Cheng, James Schwaber & Rajanikanth Vadigepalli
Images collected from serial cryostat sectioning of a cryopreserved heart was used to reconstruct the 3D context. Transcriptional profiles taken from isolated single neurons and mapped back into the previously generated 3D context.

CLARITY and three-dimensional (3D) imaging of the mouse and porcine colonic innervation

Pu-Qing Yuan, Lixin Wang, Million Mulugeta & Yvette Tache
Regional ENS 3D structure/phenotype, axonal projections and connectivity in the mouse and pig colon.

Quantification of Cholera Toxin Subunit Beta (CTb) positive neurons in the coeliac nodose and dorsal root ganglia 1 week after pancreas injection in mice

Rosemary Li, Maria Jimenez-Gonzalez & Sarah Stanley
Quantification of CTB in coeliac, nodose, and dorsal root ganglia 1 week after intrapancreatic injection

Electrophysiology in dog after subcutaneous nerve stimulation

Juyi Wan, Mu Chen, Yuan Yuan, Zhuo Wang, Changyu Shen, Michael Fishbein, Zhenhui Chen, Johnson Wong, Maria Grant, Thomas Everett & Peng-Sheng Chen
Antiarrhythmic and proarrhythmic effects of subcutaneous nerve stimulation in ambulatory dogs

Compound action potential integrated use case example

David P Nickerson & Katie Zhuang
An example dataset of a vagus nerve compound action potential for use in demonstrating the integration between the various components of the SPARC DRC. This dataset is only intended for use in demonstrations.

Anatomy and histology of the domestic pig in the context of vagus nerve stimulation

Kip A Ludwig, Megan L Settell, Nicole A Pelot, Bruce E Knudsen, Aaron Dingle, Andrea L McConico, Evan N Nicolai, James K Trevathan, J Ashley Ezzell, Erika Ross, Kenneth J Gustafson, Andrew J Shoffstall, Justin C Williams, Weifeng Zeng, Samuel Poore, Luis Populin, Aaron Suminski & Warren M Grill
Incorporation of motor efferent branches of vagus into VNS activation

Registration Year

  • 2020
    88

Resource Types

  • Dataset
    88