492 Works

Robust 3-Dimensional visualization of human colon enteric nervous system without tissue sectioning

Khaleb D Graham, Silvia Huerta-Lopez, Rajarshi Sengupta, Archana Shenoy, Sabine Schneider, Christina M Wright, Michael Feldman, Emma Furth, Amanda Lemke, Benjamin J Wilkins, Ali Naji, Edward Doolin, Marthe Howard & Robert Heuckeroth
Details a new technique to image the enteric nervous system (ENS) and other cells that control motility in the human colon in three dimensions, by combining tissue clearing, immunohistochemistry, confocal microscopy, and quantitative image analysis.

Mapping of human gastric enteroendocrine cells

Josiane Fakhry, Martin Stebbing, Billie Hunne, Yulia Bayguinov, Sean M Ward, Kent C Sasse, Brid Callaghan, Rachel M McQuade & John Furness
Characterises EECs in the human gastric fundus and corpus using immunohistochemistry and high resolution 3-D microscopy.

Influence of left vagal stimulus pulse parameters on vagal and gastric activity in rat

Matthew Ward, Thomas V Nowak, Robert Phillips, Zhenjun Tan & Terry L Powley
Influence of left vagal stimulus pulse parameters on vagal and gastric activity in rat.​

Quantification of the relationship between rat gastric nerve fibers and enteroendocrine cells (EEC)

Billie Hunne, John Furness, Martin Stebbing, Rachel M McQuade & Josiane Fahkry
This dataset examines the structural relationship between nerve endings and EECs in the rat gastric mucosa.

Quantification of rat gastric enteroendocrine cells

Billie Hunne, John Furness, Martin Stebbing, Rachel M McQuade & Josiane Fahkry
This data describes EECs within the rat stomach, including their hormone content, shapes, positions within the mucosa, relationship to other cells and regional distribution.

Selectivity of afferent microstimulation at the DRG using epineural and penetrating electrode arrays

Ameya Nanivadekar, Christopher Ayers, Max Novelli, Robert Gaunt, Doug Weber & Lee Fisher
This dataset contains over 50,000 instances of compound action potentials recorded in response to stimulation at the DRG via epineural and penetrating electrodes from nerve cuffs implanted on several distal branches of the sciatic and femoral nerve

Spatially tracked single-neuron transcriptomics of a female porcine right atrial ganglionic plexus (RAGP)

Alison Moss, Shaina Robbins, Sirisha Achanta, James Schwaber & Rajanikanth Vadigepalli
Single neurons and regional neuronal samples were collected from a female porcine RAGP through laser capture microdissection with preserved spatial tracking.

Transcriptional diversity of single neurons in the porcine right atrial ganglionic plexus (RAGP)

Alison Moss, Shaina Robbins, Sirisha Achanta, Sean Nieves, Scott Turick, James Schwaber & Rajanikanth Vadigepalli
Spatially Tracked Single Neuron Anatomical and Molecular Profiling of the Pig Right Atrial Ganglionic Plexus

Cardioneural Recordings

Jeffrey Ardell, Leonardo Guercio & Marmar Vaseghi
Methodology of neural recordings using array electrodes. Description/How to analyse for signal to noise, spike sorting and higher level analysis

Molecular Phenotype Distribution of Single Rat Intracardiac Neurons

Alison Moss, James Schwaber, Jonathan Gorky, Rajanikanth Vadigepalli, Sean Nieves, Shaina Robbins & Sirisha Achanta
Intracardiac neuron (ICN) samples were collected from a female rat heart using laser capture microdissection. We acquired transcriptomics data for 154 genes from the 151 samples we collected. Images of sampled neurons allow for 3D reconstruction of data.

Multi-scale rabbit cardiac electrophysiology models

Ignacio Pascual & Manuel Guidon
Colleen Clancy Single Cell solver with a file picker and PostPro viewer

SPARC Nerve Activity Predictor (SNAP)

Matthew P Ward
Interactive, AI-informed computational model of stimulus parameter-dependent vagal nerve responses resulting from bipolar, constant-current stimuli. Caption: Simulation of compound action potential propagation

Calcium dynamics imaging of vasoactive intestinal peptide-expressing (VIP) enteric nervous system (ENS) neurons

Joseph Margiotta & Marthe Howard
Quanatitative Morphology, Transcriptomics and Function of Enteric Neurons Expressing VIP

Chronic interfacing with the autonomic nervous system using carbon nanotube (CNT) yarn electrodes

Grant McCallum, Xiaohong Sui, Chen Qiu, Joseph Marmerstein, Yang Zheng, Thomas E. Eggers, Chuangang Hu, Liming Dai & Dominique Durand
Two carbon nanotube yarn electrodes were implanted in the rat glossophayrngeal nerve. Under isoflurane, hypoxia challenges (11 total) were administered on days 7, 10 and 16 post-implant and the resulting neural activity was captured.

Multi-scale rabbit cardiac electrophysiology models

Manuel Guidon, Mao-Tsuen Jeng, Pei-Chi Yang & Timothy J. Lewis
A computational workflow for integration and implementation of a reusable and reproducible rabbit cardiac multi-scale electrophysiology model. Caption: Illustration of ion channels and action potential propogation in cardiac tissue

Influence of left vagal stimulus pulse parameters on vagal and gastric activity in rat

Bartek Rajwa, Matthew P Ward, Robert Phillips, Terry L. Powley, Thomas V Nowak & Zhenjun T Tan
Influence of left vagal stimulus pulse parameters on vagal and gastric activity in rat.​

Functional mapping of the stomach neural circuitry - gastric electrical stimulation (GES) evoked duodenal motility in rats

Zhenjun T Tan, Matthew Ward, Robert Phillips, Xueguo Zhang, Deborah Jaffey, Logan Chesney, Bartek Rajwa, Elizabeth A Baronowsky, Jennifer L McAdams & Terry L Powley
A detailed topographic map of regional gastric effects on duodenal motility, using duodenal motor responses elicited by gastric stimulation in different regions.

Multi-scale human cardiac electrophysiology models

Colleen E. Clancy, Pei-Chi Yang & Timothy J. Lewis
A computational workflow for integration and implementation of a reusable and reproducible human cardiac multi-scale electrophysiology model.

2D Plot

Leah Reznikov
Interactive example for plotting gene expression using the RAW Graphs platform. Data are obtained from Prof. Leah Reznikov at University of Florida.

Rat Vagus Nerve Stained with Masson's Trichrome

Gabriel B. Goldhagen, J. Ashley Ezzell, Jake E. Cariello, Kara A. Clissold, Nicole A. Pelot & Warren M. Grill
Micrographs of cross sections of cervical and abdominal rat vagus nerve stained with Masson's trichrome.

Quantified Morphology of the Rat Vagus Nerve

Nicole A. Pelot, Gabriel B. Goldhagen, Jake E. Cariello & Warren M. Grill
This dataset provides binary traces of cross sections of rat vagus nerves from which we quantified the effective nerve diameters, the effective fascicle diameters, the number of fascicles, and the perineurium thickness.

Distribution of Nitregic Cholinergic and all MP Neurons

Dante Heredia
Contains source data and reconstructed images of nNOS, cholinergic and glial distribution in the murine large intestine.

2D Plot

Ignacio Pascual
2D RawGraphs viewer with one input

Hetionet

Antoine Lizee, Ari Green, Christine Hessler, Daniel S Himmelstein, Dexter Hadley, Leo Brueggeman, Pouya Khankhanian, Sabrina L Chen & Sergio E Baranzini
An integrative disease network

Multi-scale rabbit cardiac electrophysiology models

Ignacio Pascual & Manuel Guidon
This is the first approach to publish a dataset from osparc

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