This dataset contains GCaMP calcium imaging videos of spontaneous activity in enteric neurons and interstitial cells of Cajal (ICC) and responses to colon and lumbosacral spinal cord stimulation. From https://doi.org/10.1053/j.gastro.2019.04.034

Detailed analysis of the intrinsic and extrinsic nerves innervating the pig stomach

whole-body

Enteroendocrine cells (EECs) in the stomach are thought to modulate the desire to eat via nerves that send signals from the gut to the brain. In this dataset we examine the structural relationship between nerve endings and EECs in the rat gastric mucosa.

Colleen Clancy Single Cell solver with a file picker and PostPro viewer

Influence of left vagal stimulus pulse parameters on vagal and gastric activity in rat.​

Interactive, AI-informed computational model of stimulus parameter-dependent vagal nerve responses resulting from bipolar, constant-current stimuli.

Interactive, AI-informed computational model of stimulus parameter-dependent vagal nerve responses resulting from bipolar, constant-current stimuli.

Interactive example for plotting gene expression using the RAW Graphs platform. Data are obtained from Prof. Leah Resnikov at University of Florida.

A computational workflow for integration and implementation of a reusable and reproducible rabbit cardiac multi-scale electrophysiology model.

Interactive example for plotting gene expression in neonatal piglets when they are exposed to intra-airway acid or saline (control). Data are obtained from Prof. Leah Resnikov at University of Florida.

Render different human tissue types in three dimensions with the option to highlight or segment parts of: musculature, vasculature, nerve tissue, viscera and skeletal structure.

Computes the cardiac myocyte action potential for the sympathetic drive input setting on the MAP-Core portal. Caption: Illustration of a whole body flatmap (centre) and central nervous system map (left) with a neural pathway highlighted.

Three-dimensional representation of the effects of a stimulating electrode around a bundle of nerve fibers. Caption: Image of neuron stimulation model with electric field lines and gradient.

This dataset provides immunohistological images of cross sections of rat vagus nerves, identifying ChAT+ and TH+ fibers.

A computational workflow for integration and implementation of a reusable and reproducible rabbit cardiac multi-scale electrophysiology model. Caption: Illustration of ion channels and action potential propogation in cardiac tissue

iDISCO-cleared mouse hearts with PGP9.5 staining for neural structures.

Spatial distribution and morphometric characterization of vagal afferents (specifically: intraganglionic laminar endings (IGLEs)) associated with the myenteric plexus of the rat stomach.

Render different human tissue types in three dimensions with the option to highlight or segment parts of: musculature, vasculature, nerve tissue, viscera and skeletal structure. Caption: Screenshot of anatomical viewer with subject Jeduk

Interactive example for plotting gene expression using the RAW Graphs platform. Data are obtained from Prof. Leah Resnikov at University of Florida.

Cardioneural recordings

The distribution of neurons in the intrinsic cardiac nervous system (ICN) were mapped and visualized in a 3D reconstruction of a male rat heart.

Render different human tissue types in three dimensions with the option to highlight or segment parts of: musculature, vasculature, nerve tissue, viscera and skeletal structure.

Intracardiac neuron (ICN) samples were collected from a female rat heart using laser capture microdissection. We acquired transcriptomics data for 154 genes from the 151 samples we collected. Images of sampled neurons allow for 3D reconstruction of data.

Microstructural analysis of food intake as a behavioral endpoint to determine the efficacy of properly placed, optimally tuned gastric electrodes.