532 Works

Enteric neuron responses in mouse distal colon to lumbosacral spinal cord stimulation

Sarah Najjar, Kristen Smith-Edwards, Brian Davis & Kathryn Albers
This dataset contains GCaMP calcium imaging videos of spontaneous activity in enteric neurons and interstitial cells of Cajal (ICC) and responses to colon and lumbosacral spinal cord stimulation. From https://doi.org/10.1053/j.gastro.2019.04.034

Innervation of enteroendocrine cells in the gastric mucosa in human and pig - including a description of the innervation of mucosal vasculature

Madeleine Di Natale, Lalita Oparija, Billie Hunne, John Furness, Josiane Fahkry, Ruslan Pustovit & Martin Stebbing
Detailed analysis of the intrinsic and extrinsic nerves innervating the pig stomach

Generic rat brainstem scaffold

Shelley Fong, Arti Sukasem, Richard Christie & Peter Hunter
whole-body

Quantification of the relationship between rat gastric nerve fibers and enteroendocrine cells (EEC)

Billie Hunne, John B. Furness, Martin J. Stebbing & Rachel M. McQuade
Enteroendocrine cells (EECs) in the stomach are thought to modulate the desire to eat via nerves that send signals from the gut to the brain. In this dataset we examine the structural relationship between nerve endings and EECs in the rat gastric mucosa.

Multi-scale rabbit cardiac electrophysiology models

Ignacio Pascual & Manuel Guidon
Colleen Clancy Single Cell solver with a file picker and PostPro viewer

Influence of left vagal stimulus pulse parameters on vagal and gastric activity in rat

Bartek Rajwa, Matthew Ward, Robert Phillips, Terry L. Powley, Thomas V Nowak & Zhenjun T Tan
Influence of left vagal stimulus pulse parameters on vagal and gastric activity in rat.​

SPARC Nerve Activity Predictor (SNAP)

Matthew P Ward
Interactive, AI-informed computational model of stimulus parameter-dependent vagal nerve responses resulting from bipolar, constant-current stimuli.

SPARC Nerve Activity Predictor (SNAP)

Matthew P Ward
Interactive, AI-informed computational model of stimulus parameter-dependent vagal nerve responses resulting from bipolar, constant-current stimuli.

2D Plot

Ignacio Pascual
Interactive example for plotting gene expression using the RAW Graphs platform. Data are obtained from Prof. Leah Resnikov at University of Florida.

Multi-scale rabbit cardiac electrophysiology models

Ignacio Pascual & Manuel Guidon
A computational workflow for integration and implementation of a reusable and reproducible rabbit cardiac multi-scale electrophysiology model.

2D Plot

Ignacio Pascual
Interactive example for plotting gene expression in neonatal piglets when they are exposed to intra-airway acid or saline (control). Data are obtained from Prof. Leah Resnikov at University of Florida.

Anatomical Model Viewer

Ignacio Pascual
Render different human tissue types in three dimensions with the option to highlight or segment parts of: musculature, vasculature, nerve tissue, viscera and skeletal structure.

opencor-py model

Ignacio Pascual
Computes the cardiac myocyte action potential for the sympathetic drive input setting on the MAP-Core portal. Caption: Illustration of a whole body flatmap (centre) and central nervous system map (left) with a neural pathway highlighted.

3D Visualization

Esra Neufeld
Three-dimensional representation of the effects of a stimulating electrode around a bundle of nerve fibers. Caption: Image of neuron stimulation model with electric field lines and gradient.

Rat vagus nerve TH- (tyrosine hydroxylase) and ChAT- (choline acetyltransferase) positive fibers

Nicole A Pelot, J Ashley Ezzell, Jake E Cariello, Gabriel B Goldhagen, Kara A Clissold & Warren M Grill
This dataset provides immunohistological images of cross sections of rat vagus nerves, identifying ChAT+ and TH+ fibers.

Multi-scale rabbit cardiac electrophysiology models

Manuel Guidon, Mao-Tsuen Jeng, Pei-Chi Yang & Timothy J. Lewis
A computational workflow for integration and implementation of a reusable and reproducible rabbit cardiac multi-scale electrophysiology model. Caption: Illustration of ion channels and action potential propogation in cardiac tissue

Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

Benjamin Deverman, Beth Gabris-Weber, Charless Fowlkes, Guy Salama, Heike Munzberg, Jeffrey Ardell, John Tompkins, Ken Chan, Maria Jordan, Peter Hanna, Pradeep Rajendran, Rosemary Challis, Sarah Hiyari & Viviana Gradinaru
iDISCO-cleared mouse hearts with PGP9.5 staining for neural structures.

Spatial distribution and morphometric characterization of vagal afferents associated with the myenteric plexus of the rat stomach

Bartek Rajwa, Charlene Evans, Deborah M Jaffey, Elizabeth Baronowsky, Robert J Phillips & Terry L Powley
Spatial distribution and morphometric characterization of vagal afferents (specifically: intraganglionic laminar endings (IGLEs)) associated with the myenteric plexus of the rat stomach.

Anatomical Model Viewer

Ignacio Pascual
Render different human tissue types in three dimensions with the option to highlight or segment parts of: musculature, vasculature, nerve tissue, viscera and skeletal structure. Caption: Screenshot of anatomical viewer with subject Jeduk

2D Plot

Ignacio Pascual
Interactive example for plotting gene expression using the RAW Graphs platform. Data are obtained from Prof. Leah Resnikov at University of Florida.

Functional neuronal nodose recording from pig - Cardiac field chemical and mechanical stimulation

Marmar Vaseghi, Jeffrey L Ardell, Kalyanam Shivkumar & Siamak Salavatian
Cardioneural recordings

Mapping of ICN Neurons in a 3D Reconstructed Rat Heart

Alison Moss, Clara Leung, James S. Schwaber, Jin Chen, Jonathan Gorky, Leonard Eisenman, Maci Heal, Navid Farahani, Rajanikanth Vadigepalli, Shaina Robbins, Sirisha Achanta, Steve England, Susan Tappan, Todd Huffman & Zixi (Jack) Cheng
The distribution of neurons in the intrinsic cardiac nervous system (ICN) were mapped and visualized in a 3D reconstruction of a male rat heart.

Anatomical Model Viewer

Ignacio Pascual
Render different human tissue types in three dimensions with the option to highlight or segment parts of: musculature, vasculature, nerve tissue, viscera and skeletal structure.

Molecular Phenotype Distribution of Single Rat Intracardiac Neurons

Alison Moss, Clara Leung, James Schwaber, Jin Chen, Jonathan Gorky, Maci Heal, Rajanikanth Vadigepalli, Sean Nieves, Shaina Robbins, Sirisha Achanta, Susan Tappan & Zixi Cheng
Intracardiac neuron (ICN) samples were collected from a female rat heart using laser capture microdissection. We acquired transcriptomics data for 154 genes from the 151 samples we collected. Images of sampled neurons allow for 3D reconstruction of data.

Effect of electrical stimulation of vagal afferent terminals located in the stomach muscle wall on feeding behavior

Robert Phillips, Terry Powley, Bartek Rajwa, Deborah Jaffey, Pedro Irazoqui, Zhenjun Tan, Kun-Han Lu & Zhongming Liu
Microstructural analysis of food intake as a behavioral endpoint to determine the efficacy of properly placed, optimally tuned gastric electrodes.

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