5 Works

Morphological profiling of human T and NK lymphocytes by high-content cell imaging.

Loïc Dupré
The immunological synapse is a complex structure that decodes stimulatory signals into adapted lymphocyte responses. As such, it represents a unique window to monitor lymphocyte activity, owing to the development of systematic quantitative approaches applicable to primary cells. Here we demonstrate the applicability of high-content imaging to human T and NK cells and develop a pipeline for unbiased analysis of high-definition morphological profiles. Our approach reveals how distinct facets of actin cytoskeleton remodeling shape immunological...

Morphological profiling of human T and NK lymphocytes by high-content cell imaging.

Loïc Dupré
The immunological synapse is a complex structure that decodes stimulatory signals into adapted lymphocyte responses. As such, it represents a unique window to monitor lymphocyte activity, owing to the development of systematic quantitative approaches applicable to primary cells. Here we demonstrate the applicability of high-content imaging to human T and NK cells and develop a pipeline for unbiased analysis of high-definition morphological profiles. Our approach reveals how distinct facets of actin cytoskeleton remodeling shape immunological...

Morphological profiling of human T and NK lymphocytes by high-content cell imaging.

Loïc Dupré
The immunological synapse is a complex structure that decodes stimulatory signals into adapted lymphocyte responses. As such, it represents a unique window to monitor lymphocyte activity, owing to the development of systematic quantitative approaches applicable to primary cells. Here we demonstrate the applicability of high-content imaging to human T and NK cells and develop a pipeline for unbiased analysis of high-definition morphological profiles. Our approach reveals how distinct facets of actin cytoskeleton remodeling shape immunological...

Morphological profiling of human T and NK lymphocytes by high-content cell imaging.

Loïc Dupré
The immunological synapse is a complex structure that decodes stimulatory signals into adapted lymphocyte responses. As such, it represents a unique window to monitor lymphocyte activity, owing to the development of systematic quantitative approaches applicable to primary cells. Here we demonstrate the applicability of high-content imaging to human T and NK cells and develop a pipeline for unbiased analysis of high-definition morphological profiles. Our approach reveals how distinct facets of actin cytoskeleton remodeling shape immunological...

Morphological profiling of human T and NK lymphocytes by high-content cell imaging.

Loïc Dupré
The immunological synapse is a complex structure that decodes stimulatory signals into adapted lymphocyte responses. As such, it represents a unique window to monitor lymphocyte activity, owing to the development of systematic quantitative approaches applicable to primary cells. Here we demonstrate the applicability of high-content imaging to human T and NK cells and develop a pipeline for unbiased analysis of high-definition morphological profiles. Our approach reveals how distinct facets of actin cytoskeleton remodeling shape immunological...

Registration Year

  • 2022
    5

Resource Types

  • Image
    5

Affiliations

  • Paul Sabatier University
    5
  • Centre Hospitalier Universitaire de Toulouse
    1
  • Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases
    1
  • Délégation Régionale Occitanie Pyrénées
    1
  • Max F. Perutz Laboratories
    1