284 Works

Quantification of Bone Marrow Compartments in Histological Sections

Josefine Tratwal & Olaia Naveiras
Away from the Mouse H&E quantification, the current version of MarrowQuant was tested on a small set of H&E bone marrow biopsies from anonymised patients. The tool performs in a comparable way as compared to the gold standard (Pathologists’ scorings), but it needs many optimisations before validating at the level of the human bone marrow biopsies quantifications and in clinical context.

Impedance-cu-cl-boracite

Charlotte Cochard & Torsten Granzow

Pseudo-dynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left-right asymmetry

Isaac Esteban
We provide the first and complete atlas for morphometric analysis and visualization of heart tube morphogenesis, reporting morphological variability and early emergence of left-right asymmetry patterns.

LGBT+ Experiences of Custody: Gender Non-Conformity in Overtly Gendered Social Spaces

Scott McMillan
LGBT+ people are evidenced globally as being negatively impacted by the criminal justice system and face specific challenges within custodial settings due to their sexual orientation or gender identity, in what are inherently heteronormative and overtly masculine spaces culturally, and where hard lines between sex and gender are actively enforced and even reified in policy and practice at the institutional level. This dissertation sought to explore the experience of LGBT+ people in UK prisons relative...

University of Dundee Test Data for the EPSRC Supergen Wind Hub Grand Challenges Project: Screw Piles for Wind Energy Foundations (Grant no. EP/N006054/1)

Craig Davidson, Michael Brown, Jonathan Knappett & Andrew Brennan
Data collected from the centrifuge testing programme of six screw piles for the Supergen Wind Hub Grand Challenges

DRAM: A three-dimensional analytical model for the mobilisation of root reinforcement in direct shear conditions – Data repository

Gerrit Meijer, Jonathan Knappett, Glyn Bengough, Daniel Bull, Teng Liang & David Muir Wood
This dataset contains data of experiments underlying the work presented in the linked Ecological Engineering journal publication (DOI: 10.1016/j.ecoleng.2022.106621). Source code for the DRAM model (written in R) can be found in a separate repository (DOI: 10.5281/zenodo.6375587).

Parallel compound screen for infection modulators identifies re-purposing candidates against common viral infections.

Dominik Olszewski
Viral infectious diseases span a myriad of maladies, including immunosuppression, cancer, organ failure and, if lacking effective treatment, even death. While numerous targeted antiviral therapies have been developed over the past century, many viral diseases still lack effective antivirals to date. Revisiting compounds approved for other applications offers accelerated development, and automated screening and data processing boost the feasibility of the re-purposing approach. Here, we extended our high-content image-based platform on three human viruses differing...

Morphological profiling of human T and NK lymphocytes by high-content cell imaging.

Loïc Dupré
The immunological synapse is a complex structure that decodes stimulatory signals into adapted lymphocyte responses. As such, it represents a unique window to monitor lymphocyte activity, owing to the development of systematic quantitative approaches applicable to primary cells. Here we demonstrate the applicability of high-content imaging to human T and NK cells and develop a pipeline for unbiased analysis of high-definition morphological profiles. Our approach reveals how distinct facets of actin cytoskeleton remodeling shape immunological...

Multiple and Multi-dimensional Transitions of Healthcare Graduates due to COVID-19

Divya Jindal-Snape
Poster related to a study exploring the ongoing multiple and multi-dimensional transitions experienced by medicine, nursing and dentistry students due to graduate in summer 2020.

Parallel compound screen for infection modulators identifies re-purposing candidates against common viral infections.

Fanny Georgi
Viral infectious diseases span a myriad of maladies, including immunosuppression, cancer, organ failure and, if lacking effective treatment, even death. While numerous targeted antiviral therapies have been developed over the past century, many viral diseases still lack effective antivirals to date. Revisiting compounds approved for other applications offers accelerated development, and automated screening and data processing boost the feasibility of the re-purposing approach. Here, we extended our high-content image-based platform on three human viruses differing...

Reconstructing 3D histological structures using machine learning (AI) algorithms

Baskay Janos
The goal of this study is to present a methodology to create 3 dimensional structures reconstructed from high resolution histological sections by utilizing convolutional neural networks to annotate the images, discard the folded and/or torn section with an unsupervised information-theory-based clustering algorithm and apply Homography to correct perspective of each image. The resulting models then can be used for 3 dimensional micromorphometry analysis to aid the decision making process of medical professionals.

The Impact of US-Russian Security Competition on the Development of a Common European Energy Security Policy

Ioanna Mavromati
Important questions about the development of a common European energy security policy have been unexplored in the literature. The literature on European energy security focuses on the EU’s internal and external energy policy and explores issues ranging from the importance of speaking with one voice to who is leading European energy policy. Other studies focus on how much progress has been made towards the development of a common European energy security policy, what factors have...

Time Series of Media Implied Economic Sentiments (Linear Support Vector Machine)

Dooruj Rambaccussing & Andrzej Kwiatkowski
This dataset consists of economic implied sentiments based on filtering of articles based on economic policy keywords. The process of filtering is described in : Rambaccussing, D., & Kwiatkowski, A. (2020). Forecasting with news sentiment: Evidence with UK newspapers. International Journal of Forecasting, 36(4), 1501-1516. Bowden, J., Kwiatkowski, A., & Rambaccussing, D. (2019). Economy through a lens: distortions of policy coverage in UK national newspapers. Journal of Comparative Economics, 47(4), 881-906. The construction of the...

A Critical Discourse Analysis of Undergraduate Nursing Students’ Experiences of Learning Dignity-enhancing Care within the Clinical Learning Environment

Sheila Kay Douglas
Background The nursing profession has been challenged to improve standards of care in the UK. Nursing has been, and continues to be, considered a caring profession, but this reputation has been undermined since the events in Mid-Staffordshire Hospitals emerged between 2005 and 2009. The ensuing debate in the professional nursing journals sought to apportion blame under the guise of seeking solutions. Many arguments were revisited. This included scrutiny of undergraduate nursing education post-1996 when provision...

'It's Aboot Justice and Journey': Community Development Practitioners' Perspectives Reveal Insights on Practice in Scotland

Jean McEwan-Short
Community development is commonly described as contested practice, it is defined in many nuanced ways and there are challenges across the literature encouraging practitioners to engage more fully with critical thinking and transformative intent. The aim of this inquiry was to investigate community development practitioners’ perspectives on their practice in Scotland. Using an interpretivist framework, the research was designed to foreground the participants’ voices as experts on their own practice. Dyadic dialogical interviews were developed...

Developing a culturally sensitive formative feedback model for medical education in an ethnically diverse environment: a Sri Lankan case study

Thillainathan Sathaananthan
Learner-centered feedback is one of the most powerful influences in learning and achievement. However specific literature on feedback for culturally diverse environments, such as Sri Lanka is lacking. By addressing this problem, I aimed to enhance learning and teaching in medical schools. The objective was to explore and develop a culturally sensitive feedback guidance model for Medical Education. This qualitative, ethnographic, case study of the ethnically diverse Eastern University, Sri Lanka (EUSL) was emergent in...

Multiomics Biomarker Clusters for Chronic Kidney Disease in Type 2 Diabetes

Ryan Shun-Yuen Kwan
Background: Microvascular complications are common in diabetes mellitus (DM). Approximately 30% of the patients with DM developed chronic kidney disease (CKD), also known as diabetic kidney disease (DKD). DKD is associated with higher mortality risk before progressing to kidney failure. The integration of electronic health records (EHRs) and high-throughput multiomics data has shown great potential in personalised medicine. This thesis aims to identify biomarker clusters (corresponding to underlying systemic factors) of CKD progression in type...

The Role of Stakeholder Engagement in Mediating A Social Licence: A Case of The UK Shale Gas

Pearl Oruamabo
A qualitative case study approach was adopted, focusing on the development of shale gas in specific licensed areas. Semi structured interviews and documentary analysis were used to obtain the perspectives of engagement managers, regulators, local communities, Non-Governmental Organisations (NGOs) and industry experts. Collectively, all study participants were stakeholders in the shale gas development process. There was consistency in the understanding of who or what constituted as stakeholders; however, stakeholder engagement was often viewed as prescriptive,...

Regulation of Polarised Trafficking Machinery in Epithelial to Mesenchymal Transition

Matthew Niall Watt

Unconventional Blooms: The Influence of the Craft Scotland Programme of Opportunities on the Development of Craft Practitioner Entrepreneurial Identities

Lauren Baker
There is strong evidence to suggest that craft practitioners find it difficult to seize their potential as micro businesses and sole traders (Nielsen et al., 2018). Despite much work at the intersection between craft and entrepreneurial practice (Pret and Cogan, 2018), research shows a gap exists between the needs of craft business and the support provided by national organisations (Fillis, 2004; Bouette and Magee, 2015). Despite craft practitioners’ reliance on a non-linear, project-based approach to...

Non-Local Multiscale Mathematical Modelling and Numerical Approaches for Tumour-Oncolytic Viruses Interactions

Abdulhamed Alsisi
Oncolytic virus (OV) is a potential therapeutic cancer treatment since it has the ability to selectively infect and reproduce inside cancer cells, killing them while posing no threat to healthy cells. The ability of viruses to destroy cancer cells has been known for almost a century, but the specific processes behind tumour-virus interactions have only just begun to be appreciated. Due to the rapid viral replication rate, infected cancer cells come loose, releasing infectious viral...

Understanding Flipping Behaviour of Crude Oil Prices between Contango and Backwardation

Abubakar Hassan
The last four decades have witnessed extraordinary volatility in crude oil prices, and this has severe implications for the race toward achieving a net-zero carbon emission target by 2050. This thesis attempts to understand the dynamic behaviour of crude oil prices through four interrelated essays on the flipping behaviour of crude oil prices between contango and backwardation market conditions. The thesis revealed interesting findings by employing robust econometric estimation techniques and innovative ideas on weekly...

Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer

Scott Palmer
Dataset related to the named publication by Palmer et al in Biomedical Optics Express regarding autofluorescence spectroscopy of the endogenous fluorophores collagen, elastin, NADH and flavins in a developing lab based model of muscle invasive urinary bladder cancer. Data from spectroscopy measurements is included in the form of an excel spreadsheet, including day (0-21), sample number, opinion (1 = control, 2 = cancer organoid) and the values of amplitude of fluorescence and diagnostic ratios given...

High resolution imaging reveals heterogeneity in chromatin states between cells that is not inherited through cell division.

Tom Owen-Hughes & David Dickerson
In this study we introduce distinct fluorescent tags flanking a range of genomic regions and track the motion of the labelled reporters using an OMX Blaze microscope. We describe a work flow that enables 3D live cell tracking with a mean measurement error of 63 nm. We find that within individual yeast cells the separation of operator sequences exhibits substantial variation over time. Genomic loci are able to reorganize extensively below a threshold of approximately...

Registration Year

  • 2023
    57
  • 2022
    51
  • 2021
    45
  • 2020
    53
  • 2019
    29
  • 2018
    12
  • 2017
    10
  • 2016
    18
  • 2015
    9

Resource Types

  • Image
    153
  • Text
    69
  • Dataset
    49
  • Audiovisual
    5
  • Other
    4
  • Interactive Resource
    2

Affiliations

  • University of Dundee
    92
  • University of Zurich
    7
  • University of Toronto
    7
  • Paul Sabatier University
    5
  • RIKEN
    3
  • National Taiwan University Hospital
    3
  • Harvard University
    3
  • University of Maryland, Baltimore
    3
  • Sunnybrook Hospital
    2
  • University of Aberdeen
    2