3,716 Works

Medication-Wide Association Study of Dementia

Tim Wilkinson & Christian Schnier
Dataset and code list from medication-wide association study of dementia, using the Secure Anonymised Information Linkage databank Dementia electronic Cohort (SAIL-DeC). The dataset contains the hazard ratios and p-values for all medications included in the analysis (744 drugs in total). These results are from the full study population (n=551,344), of whom 16,998 developed dementia during follow-up. Numbers <10 have been masked to preserve de-identification of study participants. The code list contains Read version 2 and...

Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life

W David Hill
Genome-wide summary data for the publication of "Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life".

Measuring the vulnerability of Scottish soils to a changing climate

Roy Neilson, Alan Lilly, Matt Aitkenhead, Rebekka Artz, Nikki Baggaley, M.E. Giles, J Holland, K Loades, P Ovando Pol, M Rivington, M Roberts & J Yeluripati
The second Scottish Climate Change Adaptation Programme (SCCAP) identifies soil health as a priority research area to support sustainable soil management and ecosystem services. This follows concerns over a perceived lack of data or gaps in understanding that have been raised in both independent assessments of the first SCCAP by the Committee on Climate Change. The aim of this study is to summarise previous work on Scottish soils, explore existing datasets, and identify those metrics...


Janez Jenko
Sequence data, genotypes and ancillary files from the EC FP7 project Gene2Farm.

Temporal analysis of RNA turnover in Interferon Gamma treated bone marrow-derived macrophages

Kevin Robertson & Peter Ghazal
Bone Marrow derived macrophages (BMDM) were grown using L929 conditioned medium. On day 7, BMDM were mock-treated (16x 15cm dishes) or treated (16x 15cm dishes) with 10U/ml interferon gamma at time zero. 4-thiouridine (4sU) was then used to label newly transcribed RNA every 30 minutes for 8h (0 to 30, 30 to 60 etc. to give 16 discrete successive labellings) in mock and interferon gamma-treated samples. 16x Mock and 16x treated total samples were then...

Proteomic data from \"Sample preparation for phosphoproteomic analysis of circadian time series in Arabidopsis thaliana\"

Johanna Krahmer, Sarah Martin, Matthew Hindle, Thierry Le Bihan & Andrew Millar

MicroArray Project 1001M Denis Headon

Denis Headon
Mouse facial skin expression array. Control and retinoic acid treated.

Acceptance and Commitment Therapy for Irritable Bowel Syndrome 

Nuno Ferreira, Paul Morris & David Gillanders

LTP data from MAPT-AD experiment and APP/PS1 experiment

Iris Oren
The repository contains data from electrophysiology recordings from hippocampal brain slices to measure long term potentiation. The data contain experiments from 2 experiment. LTP_MAPTAD contains data from the following genotypes: - MAPT-null - MAPT-null x APP/PS1 - MAPT-null x rTg21221 - MAPT-null x rTg21221 x APP/PS1 LTP_APPPS1 contains data from the following genotypes: - APP/PS1 +/- - APP/PS1 -/- Data: - LTP_ARUK_Information.csv: File detailing contents of folder. Contains the following variables: - FolderName: string in...


Beatrice Alexander-Howden

CDKL5 knock-out mouse EEG recordings

Iris Oren, Alfredo Gonzalez Sulser & Peter Kind
The repository contains the raw EEG data from CDKL5 heterozygous knock-outs (KO) and litter mate wild-type (WT) mice (3-4 months old; n=3 KO, n=3 WT). The data were acquired using Opensource Instruments EEG data acquisition system, and LWDAQ/Neuroarchiver software. The data are saved in .ndf format and can be viewed using Neuroarchiver tool in LWDAQ, available here: http://alignment.hep.brandeis.edu/Software/Download/ Recording electrode coordinates: x: -2.25; y: -2.46 Reference electrode: Cerebellum The repository contains: - A README.txt file...

Sample descriptors linked to metagenomic sequencing data from human and animal enteric samples from Vietnam

The Vietnam Initiative on Zoonotic Infections (VIZIONS) Consortium & Mark Woolhouse
This dataset consists of two files, one of which is a data dictionary, the second is a spreadsheet containing details of the sources of the DNA sequence data (multiple species).

Comparative Evolutionary and Structural Analysis of the Avian and Mammalian CSF1R systems

Weronika Gutowska
General: the dataset contain sequence data, analysis pipelines and result files, which includes supporting the thesis of Maria Weronika Gutowska available from https://www.era.lib.ed.ac.uk/handle/1842/15852 Details: The folders contains files for the following project works: - Gallus gallus BAC library and BAC clones containing CSF1 gene region, including the genome sequence covering the gene and promoter region of the gene. - Comparative data to support comparative analysis of the CSF1 gene in mulitple bird species - Modelling...

Scottish Health Survey 2012-2015 datasets with linked prospective health records

Paul Kelly, Tessa Strain & Claire Fitzsimons
These datasets were obtained through ISD and were used for the PhD of Tessa Strain (completed 2018). They are being archived to preserve the version used to generate the results of the thesis.

Survey of Scottish Witchcraft, 1563 - 1736

Julian Goodare, Louise Yeoman, Lauren Martin & Joyce Miller
The Survey of Scottish Witchcraft is the result of a two-year project funded by the Economic and Social Research Council (ESRC), grant no. R000239234. The primary goal of the project was to create a database of people accused of witchcraft in Scotland between 1563 and 1736. The database was designed to enable the public and academic researchers to examine biographical and social information about accused witches; cultural and sociological patterns of witchcraft belief and accusation;...

The reduced kinome of Ostreococcus tauri: core eukaryotic signalling components in a tractable model species

Sarah F Martin, , Gerben Van Ooijen, Martin E Barrios-Llerena, , Andrew J Millar, Matthew M Hindle & Thierry Le Bihan
## Background ## The current knowledge of eukaryote signalling originates from phenotypically diverse organisms. There is a pressing need to identify conserved signalling components among eukaryotes, which will lead to the transfer of knowledge across kingdoms. Two useful properties of a eukaryote model for signalling are (1) reduced signalling complexity, (2) conservation of signalling components. The alga Ostreococcus tauri is described as the smallest free-living eukaryote. With less than 8,000 genes, it represents a highly...

Property trends in simple metals: An empirical potential approach

Alan Nichol & Graeme J Ackland

Investigating the causes of chondrocyte death in septic arthritis

Rhys Gareth Ellis Clement
Septic arthritis is a feared disease that can lead to the destruction of joints and result in significant morbidity. It is caused by an infection within a joint and up to 65% of cases are secondary to Staphylococcus aureus. Antibiotics are the mainstay of treatment and these have been so instrumental in improving the initial outcomes that there have been no major treatment advances since their introduction. The majority of cohort studies investigating septic arthritis...

Global burden of acute lower respiratory infection (ALRI) associated with influenza virus, human metapneumovirus, and human parainfluenza virus among children under five years

Xin Wang
Introduction Acute lower respiratory infection (ALRI) is one of the leading causes of mortality in children under five years. Although childhood ALRI mortality has substantially reduced over the past 15 years, continued progress will in part depend on targeted prevention and treatment against important pathogens in future. Influenza virus (IFV), human metapneumovirus (hMPV), and human parainfluenza virus (hPIV) are three important viruses causing childhood ALRI. However, global burden estimates of hMPV-associated ALRI and hPIVassociated ALRI...

Model output relating to HCHO columns over India

Luke Surl
Model input and output for the publication "Which processes drive observed variations of HCHO columns over India?", which, at the time of writing, is in Atmospheric Chemistry and Physics Discussions with DOI 10.5194/acp-2017-1017. HCHO: formaldehyde. ## Box model (CABBA/MECCA)## Contained in BOX.zip: The contents of this are the output from each run of the model, which includes a .zip of the model code. The file caaba.log in each contains all of the namelist options. For...

Kinetic model of a CO2 recycling rotary adsorption wheel for gas turbine power plants with carbon capture

Erika Alexandra Palfi
The selective recycling of carbon dioxide (CO2) upstream of post-combustion capture processes can greatly reduce both the size of equipment and capital costs by process intensification. For combined cycle gas turbine (CCGT) power plants, flue gas flow rates can be lowered by two thirds and CO2 concentration greatly increased from 4% to 14% v/v. Selective recycling of carbon dioxide (CO2) can be achieved in CCGT plants with a low pressure drop, regenerative rotary CO2 transfer...

Hybrid rotational femtosecond/picosecond coherent anti-Stokes Raman spectroscopy of nitrogen at high pressures and temperatures

Nils Torge Mecker
In this thesis, the use of two-beam hybrid rotational femtosecond/picosecond coherent anti-Stokes Raman spectroscopy (HR-CARS) for temperature measurements in nitrogen gas at high pressures (1-70 atm) and temperatures (300-1000 K) is demonstrated. An experimental setup for 1 kHz measurements of well-resolved frequency-domain HR-CARS spectra across all investigated pressures and temperatures was built. To achieve the required spectral pump/Stokes excitation bandwidth, a pulse shaper was used to create an almost transform limited 42 fs pump/Stokes pulse...

Exploration of power relations in the sexual and contraceptive choices of adolescents in South West Nigeria

Temitayo Adeola Odewusi
Background: Nigeria has one of the highest populations of young people worldwide including the widest health and economic inequalities. There are high levels of maternal deaths from pregnancy-related causes and sexually transmitted infections compared to other low-and-middle-income countries. The majority of research in this field is quantitative, highlighting a lack of education in sexual health. Nonetheless, there is a notable lack of research into the sexual experiences of the young people themselves. Aims: This study...

LD4D - Proceedings of Meeting 4-6 February 2020, Rome

Gareth Salmon
Longitudinal datasets provides valuable insights to changes over time at a national level. This session will consider which longitudinal datasets are currently available, how they contribute to knowledge in the sector, and their limitation. We will discuss how these datasets can be used to help provide the LD4D community with insights.

Palladium catalysts for cancer imaging

Paul Timothy Cowling
Lung cancer is one of the most devastating diseases with a 5-year survival rate of 17 %. The reason for this poor prognosis is that the disease is often detected at a late stages because of the reliance on low accuracy/low sensitivity diagnostic techniques such as, X-rays and CTscans. These techniques give non-specific answers as to the exact causes of a patient’s symptoms; in that they can detect if an abnormality is present, but not...

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