710 Works

Strengthening the midwifery workforce in fragile contexts: a mixed methods study from Ituri province, Democratic Republic of Congo

Amuda Baba
Skilled and motivated health workers are important to delivering quality healthcare. Ensuring their availability and equitable distribution is a key priority. Low- and middle-income countries are experiencing challenges in relation to the maternal health workforce. This situation is worse in fragile and conflict affected states. The Democratic Republic of Congo (DRC) has very high maternal mortality rates and a serious shortage of qualified skilled birth attendants. Ituri Province, in North-Eastern DRC is a fragile setting...

Delivering Effective Local Public Services: The Case of Local Area Agreements

A Nurse

Identification of LCK as a key mediator of B cell receptor (BCR)signalling in chronic lymphocytic leukaemia (CLL)

Fatima Talab
Chronic lymphocytic leukaemia (CLL) is a common type of adult leukaemia that accounts for approximately 30% of all mature B-lymphocyte malignancies. An important contributor to CLL pathogenesis is B-cell receptor (BCR) signalling which promotes survival of the malignant clone. BCR engagement on CLL cells provides survival signals by activating the NFκB pathway. Previous work to this thesis showed that CLL cells overexpress PKC-betaII and c-Abl, kinases which have been implicated in mediating NF-kappaB pathway activation...

COVID-19, Regional Inequality and the Restated Case for Devolution

Practice and Place Heseltine Institute for Public Policy

Reopening After COVID-19 Lockdown: Insights From China

Practice and Place Heseltine Institute for Public Policy

Reflections on contemporary medical professionalism; an exploration of medical practice as refracted in doctors’ narratives

Sharon Spooner
Background During a period of continuing changes in society and increasing availability of medical information, publication of patients’ views on experiences of health and illness have gained greater prominence. By contrast, studies of medical perspectives have tended to concentrate on reported discontent and implications for workforce planning while leaving broader insights and concerns under-investigated. Since the applied skills of highly trained and publicly funded clinicians are vital for safe and effective delivery of the nation’s...

Improving the Performance of Halide Perovskite Thin Film through Pb(II) Coordination Chemistry

Tianhao Yan

A Comparative Study of the Origins and Development of Municipal Housing in Liverpool and Newcastle, c.1835-1914

Bertie Dockerill
A longitudinal study anchored in deep archival research, this comparative work focuses upon the origins and development of municipal social housing in two of England’s most significant provincial urban centres, Newcastle and Liverpool, between c.1835 and 1914. This period tends to be overlooked within existent studies upon the history of British council housing, and where it is addressed, the spatial focus is usually overtly London-centric. With reference to both of these issues, therefore, this work...

The Role of Deubiquitinases in Invasive Migration and Epithelial Integrity in Drosophila

Hammed Badmos
Cell migration and epithelial maturation are central to normal development, whilst aberrant migration or loss of epithelial integrity are involved in a number of human diseases, including cancer and birth defects. We are studying these processes in the harmless fruit fly, Drosophila melanogaster, which has been intensively studied for century because of its many attractive features for genetic research. Importantly, Drosophila has proven to be a powerful system in which to identify novel molecules that...

PD-L1 expression and prediction of response to immune modulators in non-small cell lung cancer; reasons for its fragility and strategies to reduce it

Alexander Haragan
Abstract Introduction Anti-PD-1/PD-L1 immunomodulatory (IM) therapy has revolutionised the treatment of non-small cell lung cancer (NSCLC). The only ‘biomarker’ currently-validated for predicting response of these tumours to IM therapy is the extent of PD-L1 expression as detected by immunohistochemistry (IHC). Despite the overall success of this therapy in patients with NSCLC, PD-L1 expression is an imperfect predictor, some patients with tumours displaying low expression responding strongly, and some with high expression not at all. The...

Improving the diagnosis of encephalitis through analysis of the host transcriptome, proteome and metabolome.

Mark Ellul
Background Encephalitis (inflammation of the brain) is a devastating neurological condition. It is most often caused by either acute viral infection or an autoimmune process. These can be difficult to distinguish clinically and require very different treatments. Encephalitis can also be mimicked by other neurological or systemic disease states. Improved biomarkers to distinguish encephalitis from its mimics, and autoimmune from viral encephalitis, could improve diagnosis and expedite effective treatment. Previous studies have identified signatures based...

Regulating front-of-pack nutrition labelling to promote healthier diets in the European Union

Nikhil Gokani

Brain plasticity and behavioural improvement in visuomotor learning: MRI study

Abdulrahman Eid Aloufi

Development of next-generation in vitro models studying dental enamel demineralisation/remineralisation

Vivekananda Sarker

The role of endogenous retrotransposable elements in Parkinson’s disease.

Ben Middlehurst

An Action Research Proposal for Enhanced Integration of Filipino Employees into an Aging Japanese Workforce

Hajime Kunitachi
The pace of workforce decline in Japan is accelerating while its population is shrinking. Such a rapidly aging population has a direct impact on economic competitiveness, which requires the need to address the ensuing labor shortage. Although Japan’s imbalanced population could be rectified through policy to increase immigration, Japanese companies resist hiring foreign workers because immigration has long been taboo as many Japanese prize Japanese identity, ethnic homogeneity and the notion of an island country...

Enjoyment in VR games: Factors, Challenges, and Simulator Sickness Mitigation Techniques

Diego Vilela Monteiro
Although Virtual Reality (VR) has been developed for a while, the last decade has seen a surge in its popularity with the advent of commercial VR Head-Mounted Displays (HMDs), making the technology more accessible. One field that significantly benefits from VR is the entertainment industry, for example, games. Games can be challenging to design as they involve several components that are found in other types of applications as well, such as presentation, navigation, interaction with...

Managing Real-Estate Project Using Soft Systems Methodology

Mirna Zarif

Differential power processing technology for solving partial shading issues in PV system

Guanying Chu

Online Shopping Adoption and Quality of Life Among Older Consumers in China

Xue Bai

Registration Year

  • 2021

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