10,811 Works
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Mark CetiliaGenome-wide Transcriptome Analysis of Human Edpidermal Melanocyctes
Kirk Haltaufderhyde & Elena Oancea
Because human epidermal melanocytes (HEMs) provide critical protection against skin cancer,
sunburn, and photoaging, a genome-wide perspective of gene expression in these cells is
critical to understanding human skin physiology. In this study we performed high throughput
sequencing of HEMs to obtain a complete data set of transcript sizes, abundances, and splicing.
As expected, we found that melanocyte specific genes that function in pigmentation were
among the highest expressed genes. We analyzed the receptor, ion...