269 Works

N-Glycosylation effects on T cell receptor kinetics

Zachary Rollins, Bradley Harris, Steven George & Roland Faller
This methodology is an atomic-level investigation of the physiochemical effects of glycosylation on TCR dissociation kinetics. The force-dependent bond lifetime and bond strength of the DMF5 T Cell Receptor (TCR) to the MART1 peptide-Major Histocompatibility Complexes (pMHCs) were simulated using Steered Molecular Dynamics. N-glycsoylated and aglycosylated configurations were compared in triplicate. This data set contains atomic structure of the TCR and pMHC (.gro files), atomic interactions between the TCR and pMHC (hmap & cmap .csv...

Effect of Drought Stress on the Genetic Architecture of Photosynthate Allocation and Remobilization in Pods of Common Bean (Phaseolus vulgaris L.), a Key Species for Food Security

Paul Gepts, Jorge Carlos Berny Mier Y Teran, Enéas R. Konzen, Antonia Palkovic, Siu M. Tsai, Idupulapati M. Rao & Stephen Beebe
Background: Common bean is the most important staple grain legume for direct human consumption and nutrition. It complements major sources of carbohydrates, including cereals, root crop, or plantain, as a source of dietary proteins. It is also a significant source of vitamins and minerals like iron and zinc. To fully play its nutritional role, however, its robustness against stresses needs to be strengthened. Foremost among these is drought, which commonly affects its productivity and seed...

Data deposition for Complex electrophysiological remodeling in postinfarction ischemic heart failure

Bence Hegyi & Ye Chen-Izu
Heart failure (HF) following myocardial infarction (MI) is associated with high incidence of cardiac arrhythmias. Development of therapeutic strategy requires detailed understanding of electrophysiological remodeling. However, changes of ionic currents in ischemic HF remain incompletely understood, especially in translational large animal models. Here, we systematically measure the major ionic currents in ventricular myocytes from the infarct border and remote zones in a porcine model of post-MI HF. We recorded eight ionic currents during the cell’s...

INCREASING CORAL RESILIENCE TO BLEACHING THROUGH MICROBIOME MANIPULATION

Raquel Peixoto, Phillipe Rosado, Deborah Leite, Gustavo Duarte, Ricardo Chaloub, Guillaume Jospin, Jonathan Eisen, David Bourne, Ulisses Da Rocha, João Saraiva & Francisco Dini-Andreote
Although the early coral reef-bleaching warning system (NOAA/USA) is established, there is no feasible treatment that can minimize temperature bleaching and/or disease impacts on corals in the field. Here, we present the first attempts to extrapolate the widespread and well-established use of bacterial consortia to protect or improve health in other organisms (e.g., humans and plants) to corals. Manipulation of the coral-associated microbiome was facilitated through addition of a consortium of native (isolated from Pocillopora...

Data for analysis of snowmelt timing as a determinant of inflow mixing in Lake Tahoe

Derek Roberts, Shohei Watanabe & S. Geoffrey Schladow
This dataset includes data files pertinent to the manuscript, "Snowmelting timing as a determinant of inflow mixing," accepted for publication in Water Resources Research in January 2018. Included data were used for an analysis of relative stream-lake conditions as they pertain to winter climate conditions and the subsequent mixing of snowmelt inflows into the lake. Included with each of the six files listed below is a [FILENAME]_Reference.txt file with details on data collection, curation, and...

Evolution of SSR diversity from wild types to U.S. advanced cultivars in the Andean and Mesoamerican domestications of common bean (Phaseolus vulgaris)

Paul Gepts
Progress in common bean breeding requires the exploitation of genetic variation among market classes, races and gene pools. The present study was conducted to determine the amount of genetic variation and the degree of relatedness among 192 selected common bean advanced cultivars using 58 simple-sequence-repeat markers (SSR) evenly distributed along the 11 linkage groups of the Phaseolus reference map. All the lines belonged to commercial seed type classes that are widely grown in the USA...

Temperature-Dependent Dynamics of Molecular Dopant in Conjugated Polymer

Jun Li, Tucker Murrey, Souleymane Diallo & Adam Moule
Understanding the nature of dopant dynamics in the solid state is critical for improving the longevity and stability of organic electronic devices and for optimizing the dopinginduced solubility control (DISC) patterning method. In this work, we use quasi-elastic neutron scattering (QENS) to study the dynamics of the soluble p-type molecular dopant tetrafluoromethyloxycarbonyltricyanoquinodimethane (F4MCTCNQ) in the semiconductive polymer poly(3-hexylthiophene-2,5-diyl) (P3HT). Specifically, fast dynamics (ps−ns) of the dopant, such as the methyl and the methoxycarbonyl group rotations,...

Supporting data for the manuscript: Observations and modeling of the surface seiches of Lake Tahoe, USA

Derek Roberts, S. Geoffrey Schladow & Alexander Forrest
This data set was created to make the data associated with the manuscript Observations and modeling of the surface seiches of Lake Tahoe, USA, accepted for publication in Aquatic Sciences, publically available per journal convention. The publication abstract is shown below: A rich array of spatially complex surface seiche modes exists in lakes. While the amplitude of these oscillations is often small, knowledge of their spatio-temporal characteristics is valuable for understanding when they might be...

Metagenome-assembled genomes provide new insight into the microbial diversity of two thermal pools in Kamchatka, Russia

Cassandra Ettinger, Laetitia Wilkins, Guillaume Jospin & Jonathan Eisen
Culture-independent methods have contributed substantially to our understanding of global microbial diversity. Recently developed algorithms to construct whole genomes from environmental samples have further refined, corrected and revolutionized understanding of the tree of life. Here, we assembled draft metagenome-assembled genomes (MAGs) from environmental DNA extracted from two hot springs within an active volcanic ecosystem on the Kamchatka peninsula, Russia. This hydrothermal system has been intensively studied previously with regard to geochemistry, chemoautotrophy, microbial isolation, and...

Is the USDA core collection of common bean representative of genetic diversity of the species, as assessed by SNP diversity?

Paul Gepts, Saarah Kuzay & Paige Hamilton
Core collections are envisioned to be a representative subset of larger germplasm collections. They were introduced to facilitate the characterization and use of these germplasm collections. The common bean (Phaseolus vulgaris) core collection of the USDA Western Regional Plant Introduction Station was one of the first ones to be established in the early 1990s. Here, we evaluate the representativity of this common bean collection in light of the availability of a SNP platform and new...

NCST Caltrans project on sensor data error estimation

Yueyue Fan & Saurabh Maheshwari
The aim of this script is to automate the process of directed network graph formation, i.e., creation of incidence matrix, node adjacency matrix, and map the sensors to appropriate links. The data used for creating the freeway network is obtained from open street maps, whereas, the data for sensors is obtained from PeMS. The results of the algorithm will later be fed to the network sensor error estimation algorithm, that quantifies the erroneous sensors using...

Evolution of the Greater Caucasus basement and formation of the Main Caucasus Thrust, Georgia

Dylan Vasey, Eric Cowgill, Sarah Roeske, Nathan Niemi, Tea Godoladze, Irakli Skhirtladze & Salome Gogoladze
Along the northern margin of the Arabia-Eurasia collision zone in the western Greater Caucasus, the Main Caucasus Thrust (MCT) juxtaposes Paleozoic crystalline basement to the north against Mesozoic metasedimentary and volcaniclastic rocks to the south. The MCT is commonly assumed to be the trace of an active plate-boundary scale structure that accommodates Arabia-Eurasia convergence, but field data supporting this interpretation are equivocal. Here we investigate the deformation history of the rocks juxtaposed across the MCT...

Channel types predictions for the South Fork Eel River basin

Hervé Guillon, Colin F. Byrne, Belize A. Lane, Samuel Sandoval Solis & Gregory B. Pasternack
Hydrologic and geomorphic classifications have gained traction in response to the increasing need for basin-wide water resources management. Regardless of the selected classification scheme, an open scientific challenge is how to extend information from limited field sites to classify tens of thousands to millions of channel reaches across a basin. To address this spatial scaling challenge, we leveraged machine learning to predict reach-scale geomorphic channel types using publicly available geospatial data.

Effects of low-carbon energy adoption on airborne particulate matter concentrations with feedbacks to future climate over California

Anikender Kumar, Christina Zapata, Sonia Yeh, Chris Yang, Joan Ogden, Hsiang-He Lee, ShuHua Chen & Michael Kleeman
California plans to reduce emissions of long-lived greenhouse gases (GHGs) through adoption of new energy systems that will also lower concentrations of short-lived absorbing soot contained in airborne particulate matter (PM). Here we examine the direct and indirect effects of reduced PM concentrationsunder a low-carbon energy (GHG-Step) scenario on radiative forcing in California. Simulations were carried out using the source-oriented WRF/Chem (SOWC) model over California with 12 km spatial resolutionfor the year 2054. The avoided...

Transgenerational plasticity and the capacity to adapt to low salinity in the eastern oyster, Crassostrea virginica

Joanna Griffiths, Kevin Johnson, Kyle Sirovy, Mark Yeats, Francis Pan, Jerome La Peyre & Morgan Kelly
Salinity conditions in oyster breeding grounds in the Gulf of Mexico are expected to drastically change due to increased precipitation from climate change and anthropogenic changes to local hydrology. We determined the capacity of the eastern oyster, Crassostrea virginica, to adapt via standing genetic variation or acclimate through transgenerational plasticity. We outplanted oysters to either a low or medium salinity site in Louisiana for two years. We then crossed adult parents using a North Carolina...

Analytical Modeling Framework to Assess the Economic and Environmental Impacts of Residential Deliveries, and Evaluate Sustainable City Logistics Strategies

Anmol Pahwa & Miguel Jaller
In the last decade, e‐commerce has grown substantially, increasing business‐to‐business, business‐to‐consumer, and consumer‐to‐consumer transactions. As a result, there has been a continuous growth in last mile operations, especially deliveries to residential areas, bringing along externalities such as congestion, air and noise pollution, and energy consumption. This project aims to develop an analytical framework to model last mile operations based on continuous approximation techniques. The model will help estimate the economic and environmental impacts of residential...

Early maternal separation is not associated with changes in telomere length in domestic kittens (Felis catus)

Mikel Delgado, C.A.T. Tony Buffington, Melissa Bain & Karen Vernau
Objective The objective of this study was to determine if premature separation from the mother affected telomere length in domestic kittens (Felis catus) at one and eight weeks of life. Subjects were 42 orphaned kittens and 10 mother-reared kittens from local animal rescue groups and shelters. Blood (200 µl) was collected from kittens at 1 and 8 weeks of age via jugular venipuncture. Telomere length was assessed by qPCR (quantitative polymerase chain reaction) from 86...

Equate SENAS and IVD cognitive measure: Summary of methods and results

Dan Mungas, Ji Won Han, Pauline Maillard, Danielle Harvey, Evan Fletcher, Oliver Martinez, David Johnson, John Olichney, Sarah Farias, Sylvia Villeneuve, William Jagust & Charles DeCarli
Conceptually similar measures of episodic memory and executive function have been derived from different tests that compose the SENAS (Spanish and English Neuropsychological Assessment Scale) and IVD-PPG (ischemic vascular contributions to cognitive decline and dementia) neuropsychological test batteries. The purpose of this project was to create equated episodic memory and executive scores from these two batteries that are on the same measurement metric and can be combined in analyses using data from both projects. This...

Data from: Zooming in on mechanistic predator-prey ecology: integrating camera traps with experimental methods to reveal the drivers of ecological interactions

Justine Smith, Justin Suraci, Jennifer Hunter, Kaitlyn Gaynor, Carson Keller, Meredith Palmer, Justine Atkins, Irene Castañeda, Michael Cherry, Patrick Garvey, Sarah Huebner, Dana Morin, Lisa Teckentrup, Martijn Weterings & Lydia Beaudrot
1. Camera trap technology has galvanized the study of predator-prey ecology in wild animal communities by expanding the scale and diversity of predator-prey interactions that can be analyzed. While observational data from systematic camera arrays have informed inferences on the spatiotemporal outcomes of predator-prey interactions, the capacity for observational studies to identify mechanistic drivers of species interactions is limited. 2. Experimental study designs that utilize camera traps uniquely allow for testing hypothesized mechanisms that drive...

Genital morphology and the mechanics of copulation in the millipede genus Pseudopolydesmus (Diplopoda: Polydesmida: Polydesmidae)

Xavier Zahnle, Petra Sierwald, Stephanie Ware & Jason Bond
Mate choice, copulation, genital morphology, and sperm storage are not very well understood in millipedes. The use of three-dimensional x-ray computed tomography (µCT) provides new morphological data regarding millipede reproductive systems in both the female and male, including chitinous sclerites and membranes, muscles, glands, oviducts, and sperm conduits. Here we present a complete integrated account of the morphology and function of the female genital organs in the family Polydesmidae (Diplopoda: Polydesmida) using µCT, UV fluorescence...

Transportation Network Company (TNC) taxes/fees by state/city in the United States

Sam Fuller & Austin Brown
Cities and states across the U.S. are assessing fees or taxes on transportation network company (TNC) platforms, such as Uber and Lyft. The goals of these policies include traffic and emissions mitigation, as well as revenue generation, among other objectives. Our research aims to assess the goals and effectiveness of these fees in achieving some of these policy objectives, primarily congestion and emissions mitigation. The analysis addresses a core difficulty in comparing TNC fees—some fees...

Wildfire alters the disturbance impacts of an emerging infectious disease via changes to host occurrence and demographic structure

Allison Simler-Williamson, Margaret Metz, Kerri Frangioso & David Rizzo
1. Anthropogenic activities have altered historical disturbance regimes, and understanding the mechanisms by which these shifting perturbations interact is essential to predicting where they may erode ecosystem resilience. Emerging infectious plant diseases, caused by human translocation of nonnative pathogens, can generate ecologically-damaging forms of novel biotic disturbance. Further, abiotic disturbances, such as wildfire, may influence the severity and extent of disease-related perturbations via their effects on the occurrence of hosts, pathogens, and microclimates; however, these...

Landscape simplification increases vineyard pest outbreaks and insecticide use

Daniel Paredes, Jay Rosenheim, Rebecca Chaplin-Kramer, Silvia Winter & Daniel Karp
Diversifying agricultural landscapes may mitigate biodiversity declines and improve pest management. Yet landscapes are rarely managed to suppress pests, in part because researchers seldom measure key variables related to pest outbreaks and insecticides that drive management decisions. We used a 13-year government database to analyze landscape effects on European grapevine moth (Lobesia botrana) outbreaks and insecticides across ~400 Spanish vineyards. At harvest, we found pest outbreaks increased four-fold in simplified, vineyard-dominated landscapes compared to complex...

Data from: Body shape diversification along the benthic-pelagic axis in marine fishes

Sarah Friedman, Samantha Price, Katherine Corn, Olivier Larouche, Christopher Martinez & Peter Wainwright
Colonization of novel habitats can result in marked phenotypic responses to the new environment that include changes in body shape and opportunities for further morphological diversification. Fishes have repeatedly transitioned along the benthic-pelagic axis, with varying degrees of association with the substrate. Previous work focusing on individual lineages shows that these transitions are accompanied by highly predictable changes in body form. Here, we generalize expectations drawn from this literature to study the effects of habitat...

Employee airline travel preferences survey data, UC Davis GreenFLY project

Annamaria Amenta & Angela Sanguinetti
This survey data is from a study exploring the potential to promote lower-emissions air travel by providing consumers with information about the carbon emissions of possible flight choices in the context of online flight search and booking. We surveyed over 450 faculty, researchers, and staff at the University of California, Davis, and asked them to choose among hypothetical flight options for a domestic and an international university-related business trip. Emissions estimates for different flight alternatives...

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