490 Works

A prima vista. Il racconto della città per immagini tra visualità e rappresentazione

Maria Ines Pascariello
Nel vasto panorama in cui si inquadra il lavoro di ricerca volto allo studio dell’iconografia della città svolge un ruolo significativo la rappresentazione, la disciplina in grado di conservare le immagini e di produrne di sempre più adeguate alle odierne visioni. Rendendosi necessario a tale studio sia l’utilizzo di diversi strumenti di indagine, che il confronto con varie scale di riferimento, che l’apporto di varie discipline, si giunge, attraverso i contributi presenti nel primo numero...

L’immagine del paesaggio storico del Sannio nell’alta Valle Telesina. Architetture rurali e trasformazioni urbane

Giovanna Ceniccola
Il territorio dell’alta Valle Telesina nel Sannio è caratterizzato da un paesaggio rurale dai caratteri ormai storicizzati in cui l’attività produttiva agricola dell’uomo è centrale per la definizione dell’ambiente naturale e per le modalità di antropizzazione, sulla base di una forte identità culturale. Il contributo focalizza l’attenzione sui caratteri e sugli elementi del paesaggio partendo dalla conoscenza della cartografia storica, soffermandosi sul ruolo e sulle peculiarità delle architetture rurali.

Pensiero tragico e pensiero ermeneutico

Claudio Ciancio
Many philosophies take their origin from the state of uncertainty, contradiction, anguish of human condition. However in modern thought, apart from few cases (such as in Pascal), philosophies have been a strategy to avoid facing the tragic. In the nineteenth century and in the twentieth century there has been a revival of tragic thought. The present paper, however, focuses on an indirect dimension of the tragic, investing the condition of philosophical thought, namely the tension...

Nichilismo e pensiero tragico

Sergio Givone
The paper focuses on Parmenide’s necessary “being” and on the fundamental ontology derived from it. The aim is to show that this ontology is not based on the oblivion of the being, but on the power of negation’s oblivion. This power of negation is essential to think the being; otherwise, being can be thought of only as necessity, as impossibility of not being.

Pólis “Politica e nichilismo” ‒ per lumi sparsi

Vincenzo Vitiello
Reconstruction by ‘scattered fragments’ of the history of Europe, from myth to contemporary political philosophy, following the concept of the Polis as the mediation place in the conflict between law and violence. Mediation impossible, because the very origin of the law is just the violence, that it should regulate. Of this impossibility the contemporary nihilism is the awareness; the modern Metropolis – of which Vitiello depicts the ‘peculiar’ logic – is the actual experience. The...

Mimesis, kenōsis e autoreferenzialità

Emanuele Antonelli
In this paper we offer an interpretation of the inner relationship between nihilism and the tragic. With reference to the work of Heinz von Foester and to the sciences of complexity, we will argue that the essential feature of the tragic is “autoreferentiality”. Furthermore, arguing in favor of the use of the theological notion of kenōsis as the most precise description of the “history of nihilism”, we will show that the latter is to be...

First-Line Treatment of Metastatic Pancreatic Adenocarcinoma: Can We Do Better?

Man Yee Merl, Osama Abdelghany, Jia Li & Muhammad Wasif Saif
Pancreatic cancer is one of the most devastating solid tumor malignancies. Majority of patients have metastatic disease upon diagnosis. Five-year survival is less than 5% for all stages of pancreatic cancer combined. Gemcitabine has been the standard palliative therapy for advanced pancreatic cancer over the past decade. Many studies attempted to develop combination regimens, but they failed to improve overall survival in the metastatic settings. The combination of gemcitabine and erlotinib was the first combination...

Pharmacogenetics and Other Molecular Targets in the Management of Pancreatic Adenocarcinoma

Eirini Merika, Konstantinos N Syrigos & Muhammad Wasif Saif
Among various abstracts presented at the Annual Meeting of the American Society of Clinical Oncology (ASCO) held in Chicago, June 2010, four interesting abstracts focusing on pancreatic cancer merit further discussion in this post-ASCO commentary as they potentially provide insight to clinicians and hope to patients. These abstracts point to the future of pancreatic cancer management through identification of molecular targets and prognostic factors to overcome the limits of efficacious chemotherapy delivery. Image: XPD protein...

Pancreatic Cancer and Thrombosis

Manasi M Shah & Mumhammad Wasif Saif
Although pancreatic cancer is recognized as a major risk factor for venous thromboembolism, the exact magnitude of the problem is not known. The incidence varies from 17% to 57% depending on different studies. The effect of venous thromboembolism on outcomes in not well defined and there is no known independent predictor of survival. This review is an update from the current American Society of Clinical Oncology (ASCO) Annual Meeting regarding the impact of thrombotic events...

Clinical Outcome of Pancreatic Cancer Patients with Diabetes Mellitus: Is Diabetes a Poor Prognostic Factor?

Soonmo Peter Kang & Muhammad Wasif Saif
Diabetes mellitus and its related factors such as hyperinsulinemia have been linked to various cancer risks and outcomes. Previous research has offered inconsistent results in terms of relationship between diabetes and pancreatic cancers. Establishing clear association between these two entities may guide us in improving clinical outcomes of pancreatic cancer patients. Two abstracts that examined the association between diabetes mellitus and pancreatic cancer are updated in this paper. Herein, the authors report updated information from...

Cystic Lesions of the Pancreas: Clinical and Pathologic Review of Cases in a Five Year Period

Carlos E Parra-Herran, Mónica T Garcia, Loren Herrera & Pablo A Bejarano
Context Cystic lesions of the pancreas represent an important subgroup of pancreatic tumors. The characterization of these lesions has evolved in recent years, and will continue to change according to the increasing number of biopsies and resections performed. Design Pancreatectomy specimens containing cystic lesions collected over a five-year period were reviewed. Main outcome measures Demographic and pathologic features were recorded. Setting Cases were subclassified in diagnostic categories and were grouped according to the nature of...

A Case of Lipomatous Pseudohypertrophy of the Pancreas Diagnosed by Typical Imaging

Mikihiko Yasuda, Yusuke Niina, Masahiko Uchida, Nao Fujimori, Taichi Nakamura, Takamasa Oono, Hisato Igarashi, Kousei Ishigami, Yumi Yasukouchi, Kazuhiko Nakamura, Tetsuhide Ito & Ryoichi Takayanagi
Context Lipomatous pseudohypertrophy of the pancreas is an extremely rare disease, and is characterized by the replacement of pancreatic acinar cells with adipose tissue, although the pancreatic duct and islets are preserved. Case report We report the case of a 64-year-old female who was undergoing treatment for Hashimoto’s disease at a nearby clinic. For the previous two years, she had experienced an unpleasant feeling in the upper abdominal area after eating oily foods. For the...

En Bloc Resection of the Pancreatic Head and Second Part of Duodenum for a Duodenal Gastrointestinal Stromal Tumor: A Multi-Media Report

Adam E Frampton, Jan J Bong, Charis Kyriakides, Patrizia Cohen & Long R Jiao
Duodenal gastrointestinal stromal tumors are rare tumors. When these tumors arise from the second part of the duodenum they can easily be misdiagnosed as a pancreatic head cancer. A case of a 37-year-old female presenting with a one-year history of right upper quadrant pain is described here, who was subsequently found to have a mass in the head of the pancreas. Computed tomography scans showed a 2 cm hypervascular lesion lying between the head of...

Unusual Cystic Lesion of the Pancreas

Amit Javed, Sujoy Pal, Gaurav Nitin Chaubal, Nihar Ranjan Dash, Pramod Kumar Garg, Peush Sahni & Tushar Kanti Chattopadhyay
No abstract available. Image: Cyst decompression by aspiration.

Folate Deficiency in Chronic Pancreatitis

Gopalakrishna Rajesh, Banavara Narasimhamurthy Girish, Kannan Vaidyanathan, Menon Saumya & Vallath Balakrishnan
No abstract available. Image: Logo of "Amrita Institute of Medical Sciences". Cochin, Kerala, India

Reply to 'Novel Drug Targets Based on Association between Inflammation and Pancreatic Ductal Adenocarcinoma'

Ilaria Uomo, Simona Miraglia & Maurizio Pastorello
No abstract available. Image: Logo of "Provincial Health Unit". Palermo, Italy.

Un teatro ideale per il reading filosofico. Il reading filosofico Forma e finalità

Rosario Diana
Nella prima parte di questo saggio Rosario Diana (ricercatore Ispf-Cnr) – riprendendo in sintesi i risultati di una ricerca teorico-performativa esposti in un suo libro recente – illustra i caratteri della forma-reading da lui elaborata, proponendola come un possibile strumento per la disseminazione sociale dei saperi filosofici.

Un teatro ideale per il reading filosofico. Lo spazio del reading Riflessioni progettuali per un teatro ideale

Paolo Prota & Valentina Nasti
Nella seconda parte Paolo Prota (professore di Scenografia presso l’Accademia di Belle Arti di Napoli) e Valentina Nasti (sua assistente) – entrambi autori delle scenografie per due lavori firmati da Diana e rappresentati pochi mesi fa nel teatro dell’Accademia di Belle Arti di Napoli – elaborano, in uno scritto introduttivo e in una serie di tavole, il progetto di un “teatro ideale” per il reading filosofico.

Universali e ordine politico. Note su Spinoza

Roberto Evangelista
Questo contributo propone un itinerario di riflessione attraverso i testi spinoziani, per discutere il rapporto tra politica e immaginazione. Questo rapporto produce, infatti, forme di rappresentazione e di auto-rappresentazione che ricadono sulla forma e sull’organizzazione politica di una comunità. A partire dalla natura dell’immaginazione, per come viene descritta nell’Etica di Spinoza, e attraverso l’esposizione dell’esempio ebraico, Spinoza mostra una particolare idea della politica e della storia che apre a una critica dell’ideologia e collega la...

Educazione e conoscenza in Piaget e Vygotskij

Mena Iorio
Le concezioni dello sviluppo mentale sviluppate da due grandi personaggi della psicologia: Piaget e Vygotskij in quanto queste risultano essere le più importanti del nostro secolo. I motivi di tale significatività sono almeno due: l'ampiezza e la consistenza di cui ciascuna concezione da un punto di vista teorico, raggiunte mediante l'approccio interdisciplinare ai problemi adottato da entrambi gli autori; la grande risonanza che ognuna di esse ha suscitato e suscita non solo nell'ambito degli studi...

Perché noi insegniamo, adesso. Una conversazione informale sull'educazione

Giancarlo Gola
Queste sono le questioni al centro del libro di Sonia Nieto. L'Autrice, Professore Emerito alla School of Education – University of Massachusetts, Amherst, conosciuta a livello internazionale per il suo impegno per una scuola inclusiva e tra i pedagogisti più influenti del suo paese sul multiculturalismo e sulla giustizia sociale, apre con queste domande il testo “Why We Teach Now”, agganciandosi al contesto nel quale vive, opera e insegna: gli Stati Uniti, riprendendo a distanza...

Un teatro ideale per il reading filosofico. Lo spazio del reading. Riflessioni progettuali per un teatro ideale. Figure

Paolo Prota & Valentina Nasti
Figg. 1-9


Fatima Aden Abdi
Aphidius ervi (Hymenoptera, Braconidae) is an endophagous parasitoid of the pea aphid Acyrthosiphon pisum (Homoptera, Aphididae) and of various cereal aphids. Parasitized aphids show a notable inhibition of reproductive activity and metabolic alterations, which are nutritionally relevant for the developing wasp juveniles. Host regulation factors produced by A. ervi and responsible of these alterations are both of maternal origin, injected at the oviposition along with the egg, and of embryonic origin, in particular released by...

Inflammation and Pancreatic Ductal Adenocarcinoma: A Potential Scenario for Novel Drug Targets

Ilaria Uomo, Simona Miraglia & Maurizio Pastorello
No abstract available. Image: Mechanism of NF-κB action (Author: Boghog2 from Wikimedia Commons)

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