57,706 Works

DESTination RAIL – D3.5 Principles for estimating and communicating the risk of neglecting maintenance

Bryan T. Adey, Claudio Martani, Natalia Papathanasiou & Marcel Burkhalter

Multipole Electromagnet Model Cardiomag Synthetic Dataset

Samuel L. Charreyron
This dataset contains data simulating an Electromagnetic Navigation System (eMNS). The data is obtained by generating data with the multipole electromagnet model (MPEM) and models the CardioMag, an eMNS with eight electromagnets. The dataset contains magnetic fields corresponding to 3,787 distinct sets of electromagnet currents. The magnetic fields are calculated on regular grids of size Ng x Ng x Ng covering the workspace of the CardioMag. Data is provided for Ng = 3, 4, 5,...

Factors affecting vocal learning performance In juvenile songbirds

Juneseung Lee

Eleven grand challenges in single-cell data science

David Lähnemann, Niko Beerenwinkel, Katharina Jahn &
The recent boom in microfluidics and combinatorial indexing strategies, combined with low sequencing costs, has empowered single-cell sequencing technology. Thousands—or even millions—of cells analyzed in a single experiment amount to a data revolution in single-cell biology and pose unique data science problems. Here, we outline eleven challenges that will be central to bringing this emerging field of single-cell data science forward. For each challenge, we highlight motivating research questions, review prior work, and formulate open...

Automatically Detected Microsleep Episodes in the Fitness-to-Drive Assessment

Jelena Skorucak, Anneke Hertig-Godeschalk, Peter Achermann, Johannes Mathis & David R. Schreier
Study Objectives: Microsleep episodes (MSEs) are short fragments of sleep (1–15 s) that can cause dangerous situations with potentially fatal outcomes. In the diagnostic sleep-wake and fitness-to-drive assessment, accurate and early identification of sleepiness is essential. However, in the absence of a standardised definition and a time-efficient scoring method of MSEs, these short fragments are not assessed in clinical routine. Based on data of moderately sleepy patients, we recently developed the Bern continuous and high-resolution...

Epistemological Issues in Data-Driven Modeling in Climate Research

Benedikt Knüsel
Recent years have seen a dramatic increase in the volumes of data that are produced, stored, and analyzed. This advent of big data has led to commercial success stories, for example in recommender systems in online shops. However, scientific research in various disciplines including environmental and climate science will likely also benefit from increasing volumes of data, new sources for data, and the increasing use of algorithmic approaches to analyze these large datasets. This thesis...

PHYTOBASE: A global synthesis of open ocean phytoplankton occurrences

Damiano Righetti, Meike Vogt, Niklaus E. Zimmermann & Nicolas Gruber
Marine phytoplankton are responsible for half of the global net primary production and perform multiple other ecological functions and services of the global ocean. These photosynthetic organisms comprise more than 4300 marine species, but their biogeographic patterns and the resulting species diversity are poorly known, mostly owing to severe data limitations. Here, we compile, synthesize, and harmonize marine phytoplankton occurrence records from the two largest biological occurrence archives (Ocean Biogeographic Information System; OBIS, and Global...

Plant diversity effects on forage quality, yield and revenues of semi-natural grasslands

Sergei Schaub, Robert Finger, Florian Leiber, Stefan Probst, Michael Kreuzer, Alexandra Weigelt, Nina Buchmann & Michael Scherer-Lorenzen
Nature Communications, 11

Engineering synthetic gene circuits and dynamic networks in mammalian cells

Hélène Chassin

Unlocking the zinc isotope systematics of iron meteorites

Luke J. Bridgestock, Helen Williams, Mark Rehkämper, Fiona Larner, Marlène D. Giscard, Samantha Hammond, Barry Coles, Rasmus Andreasen, Bernard J. Wood, Karen J. Theis, Caroline L. Smith, Gretchen K. Benedix & Maria Schönbächler
Zinc isotope compositions (δ^66Zn) and concentrations were determined for metal samples of 15 iron meteorites across groups IAB, IIAB, and IIIAB. Also analyzed were troilite and other inclusions from the IAB iron Toluca. Furthermore, the first Zn isotope data are presented for metal-silicate partitioning experiments that were conducted at 1.5 GPa and 1650 K. Three partitioning experiments with run durations of between 10 and 60 min provide consistent Zn metal-silicate partition coefficients of ~0.7 and...

Chlorella vulgaris in a heterotrophic bioprocess: study of the lipid bioaccessibility and oxidative stability

Greta Canelli, Lukas Neutsch, Roberta Carpine, Sabrina Tevere, Francesca Giuffrida, Zhen Rohfritsch, Fabiola Dionisi, Christoph J. Bolten & Alexander Mathys
Microalgal biomass is an emerging source of several health-related compounds, including polyunsaturated fatty acids. Herein, Chlorella vulgaris was cultivated heterotrophically in a 16-L stirred tank bioreactor. The lipid oxidative stability and lipid bioaccessibility of the biomass harvested during the exponential and stationary phases were evaluated. The biomass harvested during the stationary phase showed lower lipid oxidation than that harvested during the exponential phase, likely due to the higher content of antioxidants in the former. In...

Unravelling 5 decades of anthropogenic 236U discharge from nuclear reprocessing plants

Maxi Castrillejo, Rob Witbaard, Núria Casacuberta, Christopher A. Richardson, Rob Dekker, Hans-Arno Synal & Marcus Christl
Marine biogenic materials such as corals, shells, or seaweed have long been recognized as recorders of environmental conditions. Here, the bivalve Cerastoderma edule is used for the first time as a recorder of past seawater contamination with anthropogenic uranium, specifically 236U. Several studies have employed the authorized radioactive releases, including 236U, from nuclear reprocessing plants in La Hague, France, into the English Channel, and Sellafield, England, into the Irish Sea, to trace Atlantic waters and...

The probability distribution of the reconstructed phylogenetic tree with occurrence data

Ankit Gupta, Marc Manceau, Timothy Vaughan, Mustafa Khammash & Tanja Stadler
Journal of Theoretical Biology, 488

Reactive Oxygen Species (ROS) production in organic aerosols: The importance of singlet oxygen

Nadine Borduas-Dedekind, Alessandro Manfrin, Sergey Nizkorodov, Kurtis Malecha, Gordon Getzinger & Kristopher McNeill
Geophysical Research Abstracts, 21

Storm impacts on phytoplankton community dynamics in lakes

Jason D. Stockwell, Jonathan P. Doubek, Rita Adrian, Orlane Anneville, Cayelan C. Carey, Laurence Carvalho, Lisette N. De Senerpont Domis, Gaël Dur, Marieke A. Frassl, Hans-Peter Grossart, Bas W. Ibelings, Marc J. Lajeunesse, Aleksandra M. Lewandowska, Maria E. Llames, Shin-Ichiro S. Matsuzaki, Emily R. Nodine, Peeter Nõges, Vijay P. Patil, Francesco Pomati, Karsten Rinke, Lars G. Rudstam, James A. Rusak, Nico Salmaso, Christian T. Seltmann, Dietmar Straile … & Harriet L. Wilson
In many regions across the globe, extreme weather events such as storms have increased in frequency, intensity, and duration due to climate change. Ecological theory predicts that such extreme events should have large impacts on ecosystem structure and function. High winds and precipitation associated with storms can affect lakes via short‐term runoff events from watersheds and physical mixing of the water column. In addition, lakes connected to rivers and streams will also experience flushing due...

Bender – An Educational Game for Teaching Agile Hardware Development

Daniel Omidvarkarjan, Jonas Conrad, Constantin Herbst, Christoph Klahn & Mirko Meboldt
Within this paper, an educational game is presented that transfers Agile principles for the development of physical systems. The training leverages elements of Learning Factories (LF) to simulate an Agile hardware development project within two days. By doing so, the challenges of applying Agile within the hardware domain are realistically reflected. The training revolves around a physical wire bending machine, which a development team of four participants needs to modify within a realistic engineering and...

ETH Zürich Geschäftsbericht 2019

ETH Zürich Geschäftsbericht

Towards on-chip photonic-assisted radio-frequency spectral measurement and monitoring

Luis Romero Cortés, Daniel Onori, Hugues Guillet De Chatellus, Maurizio Burla & José Azaña
Precise detection and monitoring of the frequency spectrum of microwave signals are essential to myriad scientific and technological disciplines, including both civil and defense areas, such as telecommunications, radar, biomedical instrumentation, radio astronomy, etc. Historically, microwave engineering has provided solutions for these tasks. However, current radio-frequency (RF) technologies suffer from inherent shortcomings that limit their capability to provide agile (e.g., real-time) measurements over a large operation bandwidth in energy-efficient and compact (e.g., integrated) formats. Overcoming...

Force microscopy of the Caenorhabditis elegans embryonic eggshell

Roger Krenger, Jan T. Burri, Thomas Lehnert, Bradley Nelson & Martin A. M. Gijs
Assays focusing on emerging biological phenomena in an animal’s life can be performed during embryogenesis. While the embryo of Caenorhabditis elegans has been extensively studied, its biomechanical properties are largely unknown. Here, we demonstrate that cellular force microscopy (CFM), a recently developed technique that combines micro-indentation with high resolution force sensing approaching that of atomic force microscopy, can be successfully applied to C. elegans embryos. We performed, for the first time, a quantitative study of...

MOBIS-COVID19/05: Results as of 04/05/2020

Joseph Molloy, Christopher Tchervenkov, Thomas Schatzmann, Beaumont Schoeman, Beat Hintermann & Kay W. Axhausen
On March 16, 2020, 3700 participants who completed the MOBIS study between September 2019 and January 2020 were invited to reinstall the GPS Logger and Travel Diary App ‘Catch-My-Day’, developed by MotionTag, to record their mobility behaviour during the period of special measures implemented to control the spread of the Corona Virus. The first 4 weeks of mobility data from the original MOBIS Study is taken for each participant as a baseline against which to...

Überprüfung bezüglich Erdbeben von Holzbalkendecken in Bestandesbauten

Thomas Wenk, Roland Brunner, João P. Almeida & Katrin Beyer
D-A-CH-Mitteilungsblatt [enthalten in: Bauingenieur], 95 (4)

Automated computer-assisted quantitative analysis of intact murine lungs at the alveolar scale

Goran Lovric, Ioannis Vogiatzis Oikonomidis, Rajmund Mokso, Marco Stampanoni, Matthias Roth-Kleiner & Johannes C. Schittny
Using state-of-the-art X-ray tomographic microscopy we can image lung tissue in three dimensions in intact animals down to a micrometer precision. The structural complexity and hierarchical branching scheme of the lung at this level of details, however, renders the extraction of biologically relevant quantities particularly challenging. We have developed a methodology for a detailed description of lung inflation patterns by measuring the size and the local curvature of the parenchymal airspaces. These quantitative tools for...

Emotion Regulating Attentional Control Abnormalities In Major Depressive Disorder: An Event-Related Potential Study

Bin Hu, Juan Rao, Xiaowei Li, Tong Cao, Jianxiu Li, Dennis Majoe & Jürg Gutknecht
Major depressive disorders (MDD) exhibit cognitive dysfunction with respect to attention. The deficiencies in cognitive control of emotional information are associated with MDD as compared to healthy controls (HC). However, the brain mechanism underlying emotion that influences the attentional control in MDD necessitates further research. The present study explores the emotion-regulated cognitive competence in MDD at a dynamic attentional stage. Event-Related Potentials (ERPs) were recorded from 35 clinical MDD outpatients and matched HCs by applying...

A unifying Bayesian account of contextual effects in value-based choice

Francesco Rigoli, Christoph Mathys, Karl J. Friston & Raymond J. Dolan
Empirical evidence suggests the incentive value of an option is affected by other options available during choice and by options presented in the past. These contextual effects are hard to reconcile with classical theories and have inspired accounts where contextual influences play a crucial role. However, each account only addresses one or the other of the empirical findings and a unifying perspective has been elusive. Here, we offer a unifying theory of context effects on...

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