9,538 Works

Assessing the stability of aquatic extracellular enzymes

Christine Egli
Aquatic extracellular enzymes are important drivers of organic matter cycling in surface waters. Heterotrophic bacteria secret extracellular enzymes to break down macromolecular carbon into bioavailable substrates. Once secreted, these enzymes are exposed to different environmental conditions and undergo transformation processes which can compromise enzyme stability and consequently alter their affect on biogeochemical cycles. The activity of an enzyme critically depends on the molecular integrity of the active site residues. Simultaneous assessment of transformations in the...

Labor Market Effects of Currency Appreciation: The Case of Switzerland

Peter Egger, Johannes Schwarzer & Anirudh Shingal
Recent work on labour market effects of globalization has generated both academic and populist interests. However, this work has focussed exclusively on the manufacturing sector. Moreover, general equilibrium effects of globalization have received little attention. This study contributes to filling both these gaps by examining the general equilibrium effects of external exposure on the labor market in Switzerland. We exploit exogenous exchange rate movements to identify trade-induced shocks across all sectors of the Swiss economy...

The Implications of Central Bank Transparency for Uncertainty and Disagreement

Jitmaneeroj Boonlert, Michael J. Lamla & Andrew Wood
Using survey data from 25 economies we provide evidence that greater transparency surrounding monetary policy reduces uncertainty of interest rates and inflation, primarily by reducing uncertainty that is common to agents rather than disagreement between agents. This suggests that studies that focus on disagreement as a proxy for uncertainty understate the benefits of monetary policy transparency. The adoption of inflation targets and forward guidance are both associated with lower uncertainty, although inflation targets have a...

Design and Specification of Batteryless Sensing Systems

Andres Gomez
TIK Schriftenreihe, 176

Parliaments in International Politics

Jofre Rocabert
The contestation of international decision-making is one of the most pressing problems affecting both national institutions and international organizations. As the main arenas of communal decision-making, the involvement of parliaments may be a solution to the legitimacy shortages of international decisions and the institutional paralysis that this may ensue. This dissertation examines two distinct processes that reveal the current place of parliaments in international politics. In the first part of my dissertation, I focus on...

Growth of Epithelial Organoids in a Defined Hydrogel

Nicolas Broguiere, Luca Isenmann, Christian Hirt, Till Ringel, Silja Placzek, Emma Cavalli, Femke Ringnalda, Lukas Villiger, Richard Züllig, Roger Lehmann, Gerhard Rogler, Markus H. Heim, Julia Schüler, Marcy Zenobi-Wong & Gerald Schwank
Epithelial organoids are simplified models of organs grown in vitro from embryonic and adult stem cells. They are widely used to study organ development and disease, and enable drug screening in patient‐derived primary tissues. Current protocols, however, rely on animal‐ and tumor‐derived basement membrane extract (BME) as a 3D scaffold, which limits possible applications in regenerative medicine. This prompted us to study how organoids interact with their matrix, and to develop a well‐defined hydrogel that...

Experimental and numerical investigation of blade resonance in a centrifugal compressor for varying gas properties

Carsten Degendorfer, Reza S. Abhari, Klemens Vogel & René Hunziker
Journal of the Global Power and Propulsion Society, 2

Experimental And Numerical Investigation Of Blade Resonance In A Centrifugal Compressor For Varying Gas Properties

Carsten Degendorfer, Reza S. Abhari, Klemens Vogel & René Hunziker
The blades of centrifugal compressors are exposed to unsteady forces during operation which can result in resonance response conditions and failures due to high cycle fatigue. A typical source of excitation is the unsteady fluid structure interaction between the impeller blades and the downstream vaned diffuser. Centrifugal compressors are operated with various working fluids with a wide range of applications in the power and process industry. Understanding the excitation mechanisms for different working fluids will...

PSI-Jahresbericht 2001: Allgemeiner Teil

PSI-Jahresbericht

Fundamental analysis of the cutting edge micro-geometry in orthogonal machining of unidirectional Carbon Fibre Reinforced Plastics (CFRP)

Lukas Seeholzer, Robert Voss, Frank Grossenbacher, Friedrich Kuster & Konrad Wegener
Machining of carbon fibre reinforced plastics (CFRP) is closely related to strong abrasive tool wear and represents a significant process challenge due to its anisotropic material structure and brittle fracture behavior. Furthermore, machining of unidirectional CFRP material shows a significant increase in process forces due to tool wear effects, resulting in a changing micro-geometry of the cutting edge. This research work aims to give a detailed analysis of the tool wear behavior with respect to...

Towards understanding corrosion initiation in concrete – Influence of local electrochemical properties of reinforcing steel

Lucas Michel & Ueli Angst
The ageing of reinforced concrete (RC) structures in the industrialized countries increases the probability of durability issues. The mechanism of chloride-induced corrosion, the most common deterioration process in RC structures, is still not well understood. Improvement in the understanding of localized corrosion initiation is crucially required to allow for cost efficient and durable maintenance of the existing infrastructures and for service life design of new structures. This study reports results from localized electrochemical characterization of...

Amphibole and apatite insights into the evolution and mass balance of Cl and S in magmas associated with porphyry copper deposits

Cyril Chelle-Michou & Massimo Chiaradia
Chlorine and sulfur are of paramount importance for supporting the transport and deposition of ore metals at magmatic–hydrothermal systems such as the Coroccohuayco Fe–Cu–Au porphyry–skarn deposit, Peru. Here, we used recent partitioning models to determine the Cl and S concentration of the melts from the Coroccohuayco magmatic suite using apatite and amphibole chemical analyses. The pre-mineralization gabbrodiorite complex hosts S-poor apatite, while the syn- and post-ore dacitic porphyries host S-rich apatite. Our apatite data on...

Reliability of Wearable-Sensor-Derived Measures of Physical Activity in Wheelchair-Dependent Spinal Cord Injured Patients

Sophie Schneider, Werner Popp, Michael Brogioli, Urs Albisser, László Demkó, Isabelle Debecker, Inge-Marie Velstra, Roger Gassert & Armin Curt
Physical activity (PA) has been shown to have a positive influence on functional recovery in patients after a spinal cord injury (SCI). Hence, it can act as a confounder in clinical intervention studies. Wearable sensors are used to quantify PA in various neurological conditions. However, there is a lack of knowledge about the inter-day reliability of PA measures. The objective of this study was to investigate the single-day reliability of various PA measures in patients...

Physical data for the 54 most voluminous low latitude reservoirs

R. Scott Winton, Elisa Calamita & Bernhard Wehrli

Pore geometry as a limiting factor for anion diffusion in argillaceous rocks

Cornelia Wigger, Michael Plötze & Luc R. Van Loon
Several barrier types are envisaged to minimize the release of radionuclides from waste matrices into groundwater. In a number of countries argillaceous rocks make up the natural barrier that will isolate radioactive substances from the aquifer. The present study addresses the influence of pore geometry as a limiting factor for anion diffusion in argillaceous rocks. Irrespective of the pore core size, anion diffusion can be limited by the pore-size opening, i.e. if the pore opening...

Hydraulic Characteristics and Flow-field Related Hemocompatibility of Rotary Blood Pump Designs

Stefan Boës
Rotary blood pumps (RBPs) are implanted into patients with end-stage heart failure to support the left heart by pumping blood from the left ventricle to the aorta. Although the survival rate of patients supported with RBPs has increased substantially over the last decades, patients still suffer from a high incidence of adverse events such as infection, major bleeding or cerebral strokes. Many of these adverse events can be linked to the hemocompatibility of the RBP....

COUNTDOWN - A Run-time Library for Application-agnostic Energy Saving in MPI Communication Primitives

Daniele Cesarini, Andrea Bartolini, Piero Bonfà, Carlo Cavazzoni & Luca Benini
Energy and power consumption are prominent issues in today’s supercomputers and are foreseen as a limiting factor of future installations. In scientific computing, a significant amount of power is spent in the communication and synchronization-related idle times among distributed processes participating to the same application. However, due to the time scale at which communication happens, taking advantage of low-power states to reduce power in idle times in the computing resources, may introduce significant overheads. In...

A Probabilistic Damage Model for Predicting Plaster Cracks on Unreinforced Masonry Walls

Giuseppe Abbiati, Marco Broccardo, Max Didier, Katrin Beyer & Bozidar Stojadinovic

Advanced continuum methods for industrial nanoelectronic device simulation

Anne Ziegler

Energy Saving and Thermal Management Opportunities in a Workload-Aware MPI Runtime for a Scientific HPC Computing Node

Daniele Cesarini, Andrea Bartolini & Luca Benini
With the advent of a new generation of supercomputers characterized by tightly-coupled integration of a large-number of powerful processing cores in the same die, energy and temperature walls are looming threats to the growth in computational power. Scientific computing is characterized by a single application running in parallel on multiple nodes and cores until termination. The message-passing programming model is a widely adopted paradigm for explicitly handling data-sharing between processes of the same application. As...

On the Cost of Freedom From Interference in Heterogeneous SoCs

Björn Forsberg, Luca Benini & Andrea Marongiu
Proceedings of the 21st International Workshop on Software and Compilers for Embedded Systems (SCOPES)

From Coarse to Fine: Robust Hierarchical Localization at Large Scale

Paul-Edouard Sarlin, Cesar Cadena, Roland Siegwart & Marcin Dymczyk

How many small water reservoirs are there? A global survey using multi-spectral Imagery

Bassem Mady, Peter Lehmann & Dani Or
Geophysical Research Abstracts, 20

LandmarkBoost: Efficient Visual Context Classifiers for Robust Localization

Marcin Dymczyk, Igor Gilitschenski, Juan Nieto, Simon Lynen, Bernhard Zeisl & Roland Siegwart
2018 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)

Higher species richness enhances yield stability in intensively managed grasslands with experimental disturbance

Eamon Haughey, Matthias Suter, Daniel Hofer, Nyncke J. Hoekstra, Jennifer C. McElwain, Andreas Lüscher & John A. Finn
Climate models predict increased frequency and severity of drought events. At an Irish and Swiss site, experimental summer droughts were applied over two successive years to grassland plots sown with one, two or four grassland species with contrasting functional traits. Mean yield and plot-to-plot variance of yield were measured across harvests during drought and after a subsequent post-drought recovery period. At both sites, there was a positive relationship between species richness and yield. Under rainfed...

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