1,727,214 Works

Values for each superfamily in the dataset for full and trimmed profiles

James A Casbon & Mansoor AS Saqi
Copyright information:Taken from "Analysis of superfamily specific profile-profile recognition accuracy"BMC Bioinformatics 2004;5():200-200.Published online 16 Dec 2004PMCID:PMC543460.Copyright © 2004 Casbon and Saqi; licensee BioMed Central Ltd.

Mean RMSD of the trimmed profiles versus conservation for superfamilies in our dataset

James A Casbon & Mansoor AS Saqi
Copyright information:Taken from "Analysis of superfamily specific profile-profile recognition accuracy"BMC Bioinformatics 2004;5():200-200.Published online 16 Dec 2004PMCID:PMC543460.Copyright © 2004 Casbon and Saqi; licensee BioMed Central Ltd.

The comparison is based on the data set, the population number is set to 50 and the mutation probability is set to 0

Yi Lu, , Farshad Fotouhi, & Susan J Brown
Copyright information:Taken from "Incremental genetic K-means algorithm and its application in gene expression data analysis"BMC Bioinformatics 2004;5():172-172.Published online 28 Oct 2004PMCID:PMC543472.Copyright © 2004 Lu et al; licensee BioMed Central Ltd.0001. 100 iterations of three algorithms, IGKA, FGKA and HGKA, are shown in the Figure. The running time for each iteration of FGKA is almost fixed while the running time for IGKA is much higher than FGKA at the beginning and decrease very sharply at late...

Area of surgically removed prostate demonstrating microfoci of adenocarcinoma associated with a localization of small-B cell lymphoma (CLL) (EE, 40X)

Riccardo Ballario, Paolo Beltrami, Stefano Cavalleri, Lorenzo Ruggera, Maria Grazia Zorzi & Walter Artibani
Copyright information:Taken from "An unusual pathological finding of chronic lymphocitic leukemia and adenocarcinoma of the prostate after transurethral resection for complete urinary retention: case report"BMC Cancer 2004;4():95-95.Published online 22 Dec 2004PMCID:PMC544353.Copyright © 2004 Ballario et al; licensee BioMed Central Ltd.

Flow of data from hospitals to New York State Department of Health Alzheimer's Disease and Other Dementias Registry, 2003

Patricia P. Lillquist
Copyright information:Taken from "Challenges in Surveillance of Dementias in New York State "Preventing Chronic Disease 2003;1(1):-.Published online 15 Dec 2003PMCID:PMC544531.

Ras families and sub-families defined by singular vectors (labeled at right)

Gary W Stuart & Michael W Berry
Copyright information:Taken from "An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage"BMC Bioinformatics 2004;5():204-204.Published online 17 Dec 2004PMCID:PMC544558.Copyright © 2004 Stuart and Berry; licensee BioMed Central Ltd. For comparison, dominant peptide strings identified by SVD (boxes) are shown within a Clustal-X alignment. The aligned region corresponds to the first 181aa's of the 192aa Human Rac3 protein. Protein sequences are labeled by gi# (or ensemble# for Frup). Asterisks (*) indicate...

Left singular vectors depicted as tetrapeptide projection value frequency distributions

Gary W Stuart & Michael W Berry
Copyright information:Taken from "An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage"BMC Bioinformatics 2004;5():204-204.Published online 17 Dec 2004PMCID:PMC544558.Copyright © 2004 Stuart and Berry; licensee BioMed Central Ltd. Distributions for singular vectors 277 (A) and 389 (B) are shown in purple, normal distributions having the same standard deviation are shown in blue. For both distributions, the vast majority of values fall between 0.015 and -0.015. Dashed lines mark the cut-off...

Effect of 24 h pre-treatment with TPL on DOX ICvalues obtained in HCT116, HT29, HCT116 E6 and HCT116 p21-/- cells following 1 h exposure to DOX and 72 h in drug-free medium

Raffaella Ravizza, Marzia B Gariboldi, Laura Passarelli & Elena Monti
Copyright information:Taken from "Role of the p53/p21 system in the response of human colon carcinoma cells to Doxorubicin"BMC Cancer 2004;4():92-92.Published online 15 Dec 2004PMCID:PMC544559.Copyright © 2004 Ravizza et al; licensee BioMed Central Ltd. For each cell line, two TPL concentrations corresponding to ICand IC(see table 2), were used. Mean ± s.e.m. of 4–6 experiments.

Effect of compression on mean best CS (Correspondence Score) at various threshold values

Noam Kaplan, Moriah Friedlich, Menachem Fromer & Michal Linial
Copyright information:Taken from "A functional hierarchical organization of the protein sequence space"BMC Bioinformatics 2004;5():196-196.Published online 14 Dec 2004PMCID:PMC544566.Copyright © 2004 Kaplan et al; licensee BioMed Central Ltd. (A) Mean best CS shown here is calculated for the InterPro keywords. Mean best CS decreases from right to left, as more clusters are eliminated due to compression. Filled circles represent the mean best CS for compression according to LT thresholds. Open circles represent the mean best CS...

Schematic representation of folding, aggregation and degradation processes

Pascal Philibert & Pierre Martineau
Copyright information:Taken from "Directed evolution of single-chain Fv for cytoplasmic expression using the β-galactosidase complementation assay results in proteins highly susceptible to protease degradation and aggregation"Microbial Cell Factories 2004;3():16-16.Published online 17 Dec 2004PMCID:PMC544847.Copyright © 2004 Philibert and Martineau; licensee BioMed Central Ltd. In the scheme presented, the newly translated protein (left) is assumed to proceed through two alternative pathways: either it folds to give the folded protein (soluble native) or it evolves via a side...

The summary of the trial design includes: the screening procedure, the randomisation, the intervention and the points in time at which the effects of the intervention are measured

Ans Nicolaides-Bouman, Erik Van Rossum, Gertrudis IJM Kempen & Paul Knipschild
Copyright information:Taken from "Effects of home visits by home nurses to elderly people with health problems: design of a randomised clinical trial in the Netherlands [ISRCTN92017183]"BMC Health Services Research 2004;4():35-35.Published online 15 Dec 2004PMCID:PMC544877.Copyright © 2004 Nicolaides-Bouman et al; licensee BioMed Central Ltd.

Expression of rF6Hy/rF6Hys as detected by immunoblotting using anti-His antibody (A) Time course induction of rF6Hy

Dominique Anzellotti &
Copyright information:Taken from "Molecular characterization and functional expression of flavonol 6-hydroxylase"BMC Plant Biology 2004;4():20-20.Published online 13 Dec 2004PMCID:PMC544895.Copyright © 2004 Anzellotti and Ibrahim; licensee BioMed Central Ltd. (B) Purification of rF6Hy on Ni-NTA. Lanes: 1, Bound 2 (2 mL eluate; 5 μg); 2, Bound 1 (1 ml eluate; 5 μg); 3, wash (10 μg); 4, flow-through (10 μg). (C) Time course induction of rF6Hys. (D) Purification of rF6Hys on Ni-NTA. Lanes: 1, Bound 3 (3...

Section of the corneal button from a case of bacterial keratitis showing epithelial ulceration

Geeta K Vemuganti, , Ghazala Iftekhar, Prashant Garg & Savitri Sharma
Copyright information:Taken from "Keratocyte loss in corneal infection through apoptosis: a histologic study of 59 cases"BMC Ophthalmology 2004;4():16-16.Published online 24 Dec 2004PMCID:PMC545077.Copyright © 2004 Vemuganti et al; licensee BioMed Central Ltd. Note the dense the inflammatory infiltrates in the anterior two-thirds of corneal stroma and the quiet deep corneal stroma. (Hematoxylin and eosin, ×125)

Examples of tissue-specific AS events in human genes with evidence of splice conservation in orthologous mouse genes

Gene Yeo, Dirk Holste, Gabriel Kreiman & Christopher B Burge
Copyright information:Taken from "Variation in alternative splicing across human tissues"Genome Biology 2004;5(10):R74-R74.Published online 13 Sep 2004PMCID:PMC545594.Copyright © 2004 Yeo et al.; licensee BioMed Central Ltd. Human fragile X mental retardation syndrome-related () gene splicing detected in brain-derived EST sequences. exhibited two alternative mRNA isoforms differing by skipping/inclusion of exons E15 and E16. Exclusion of E16 creates a shift in the reading-frame, which is predicted to result in an altered and shorter carboxy terminus. The exon-skipping...

Higher variation in TFs is independent of sampling depth from each tissue

Bahar Taneri, Ben Snyder, Alexey Novoradovsky & Terry Gaasterland
Copyright information:Taken from "Alternative splicing of mouse transcription factors affects their DNA-binding domain architecture and is tissue specific"Genome Biology 2004;5(10):R75-R75.Published online 30 Sep 2004PMCID:PMC545595.Copyright © 2004 Taneri et al.; licensee BioMed Central Ltd. Absolute number of variant TF transcripts per tissue. Absolute number of all variant transcripts per tissue. For each tissue (labeled to the right of each data point), -axis: ratio of variant TF transcripts to all variant transcripts (= (/)/(/)); -axis: absolute numbers...

Distribution of functional distances between duplicated pairs based on Gene Ontology annotations

Anaïs Baudot, Bernard Jacq & Christine Brun
Copyright information:Taken from "A scale of functional divergence for yeast duplicated genes revealed from analysis of the protein-protein interaction network"Genome Biology 2004;5(10):R76-R76.Published online 15 Sep 2004PMCID:PMC545596.Copyright © 2004 Baudot et al.; licensee BioMed Central Ltd. The annnotations are for 'Biological Process' (blue), 'Molecular Function' (purple) and 'Cellular Component' (light yellow). Distributions of distances (ranging from 0 to 1) based on annotations for the 460 duplicated pairs, (a, inset) randomly selected pairs and the 41 duplicated...

Isoforms of alternatively spliced genes are more heterogeneous across different tissues than within single tissues

Bahar Taneri, Ben Snyder, Alexey Novoradovsky & Terry Gaasterland
Copyright information:Taken from "Alternative splicing of mouse transcription factors affects their DNA-binding domain architecture and is tissue specific"Genome Biology 2004;5(10):R75-R75.Published online 30 Sep 2004PMCID:PMC545595.Copyright © 2004 Taneri et al.; licensee BioMed Central Ltd. The blue bars represent the ratio of all TF clusters with multiple isoforms within a tissue to all TF clusters with only one isoform within each tissue. The red bars represent the ratio of all variant clusters with multiple isoforms within a...

Venn diagram comparing the orthologous gene complements of ATCC 14580, 168 and C-125

Michael W Rey, , Beth A Nelson, Shari D Brody-Karpin, Elizabeth J Zaretsky, Maria Tang, Alfredo Lopez De Leon, Henry Xiang, Veronica Gusti, Ib Groth Clausen, Peter B Olsen, Michael D Rasmussen, Jens T Andersen, Per L Jørgensen, Thomas S Larsen, Alexei Sorokin, Alexander Bolotin, Alla Lapidus, Nathalie Galleron, & Randy M Berka
Copyright information:Taken from "Complete genome sequence of the industrial bacterium and comparisons with closely related species"Genome Biology 2004;5(10):r77-r77.Published online 13 Sep 2004PMCID:PMC545597.Copyright © 2004 Rey et al.; licensee BioMed Central Ltd. Numbers in purple boxes indicate the number of pairwise orthologs between adjacent species (BLAST threshold E = 1 × 10). Numbers in the outer circles represent the total number of CDSs predicted in each genome, numbers in areas of overlap indicate the number of...

Relationship between age and physical distributions of complete elements

Vini Pereira
Copyright information:Taken from "Insertion bias and purifying selection of retrotransposons in the genome"Genome Biology 2004;5(10):R79-R79.Published online 29 Sep 2004PMCID:PMC545599.Copyright © 2004 Pereira; licensee BioMed Central Ltd. Insertions into the short arms of chromosomes II and IV were excluded for clarity. These arms contain extensive heterochromatin away from the centromeres, in nucleolar-organizing regions that juxtapose their telomeres, and in a knob []. In addition, their short length implies that the pericentromeric heterochromatin, which spans around 1-1.5...

CHX chase analysis by western blot of three labile EGFP-fused library clones

Xin Jiang, Philip Coffino &
Copyright information:Taken from "Development of a method for screening short-lived proteins using green fluorescent protein"Genome Biology 2004;5(10):R81-R81.Published online 28 Sep 2004PMCID:PMC545601.Copyright © 2004 Jiang et al.; licensee BioMed Central Ltd. Cells were individually transfected with GFP-cDNA clones representing splicing factor SRp30c, guanine nucleotide-binding regulatory protein or cervical cancer proto-oncogene p40. Transfected cells were treated with CHX and were collected immediately thereafter or after 1, 2 or 3 hours for western blot analysis using anti-EGFP polyclonal...

Cycloheximide chase analysis by western blot of three full-length myc-tagged cDNAs

Xin Jiang, Philip Coffino &
Copyright information:Taken from "Development of a method for screening short-lived proteins using green fluorescent protein"Genome Biology 2004;5(10):R81-R81.Published online 28 Sep 2004PMCID:PMC545601.Copyright © 2004 Jiang et al.; licensee BioMed Central Ltd. Cells were transiently transfected to express splicing factor SRp30c, guanine nucleotide-binding regulatory protein or cervical cancer proto-oncogene p40, each with an amino-terminal myc epitope tag. Transfected cells were treated with CHX and samples subjected to western blot analysis using anti-myc antibody. The mobility of protein...

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