1,536,554 Works

Responsiveness and minimal clinically important difference of SGRQ-I and K-BILD in idiopathic pulmonary fibrosis

Thomas Skovhus Prior, Nils Hoyer, Ole Hilberg, Saher Burhan Shaker, Jesper Rømhild Davidsen & Elisabeth Bendstrup
Abstract Background Idiopathic pulmonary fibrosis (IPF) specific version of St. George’s Respiratory Questionnaire (SGRQ-I) and King’s Brief Interstitial Lung Disease questionnaire (K-BILD) are validated health-related quality of life (HRQL) instruments, but no or limited data exist on their responsiveness and minimal clinically important difference (MCID). The objectives of this study were to assess responsiveness of SGRQ-I and K-BILD and determine MCID separately for deterioration and improvement in a large, prospective cohort of patients with IPF...

Predicting MCI progression with FDG-PET and cognitive scores: a longitudinal study

, , Yu Zhao, Tao Hu, Zhe Zhang, & Bin Hu
Abstract Background Mild cognitive impairment (MCI) is an intermediate stage between normal aging and dementia. Studies on MCI progression are important for Alzheimer’s disease (AD) prevention. 18F fluoro-deoxy-glucose positron emission tomography (FDG-PET) has been proven to be a powerful tool for measuring cerebral glucose metabolism. In this study, we proposed a classification framework for MCI prediction with both baseline and multiple follow-up FDG-PET scans as well as cognitive scores of 33 progressive MCI (pMCI) patients...

Additional file 1 of An efficient in vitro regeneration system from different wild apple (Malus sieversii) explants

, T. A. Bozorov, , , , &
Additional file 1. Callus induction in different SIM from 30-day-old leaf and stem explants.

Additional file 2 of An efficient in vitro regeneration system from different wild apple (Malus sieversii) explants

, T. A. Bozorov, , , , &
Additional file 2. Adventitious shoots regenerated from 60-day-old leaf and stem explants from different SIM.

Additional file 1 of Effect of Helicobacter pylori eradication on reflux esophagitis and GERD symptoms after endoscopic resection of gastric neoplasm: a single-center prospective study

Hee Kyong Na, Jeong Hoon Lee, Se Jeong Park, Hee Jung Park, Sun Ok Kim, Ji Yong Ahn, Do Hoon Kim, Kee Wook Jung, Kee Don Choi, Ho June Song, &
Additional file 1.

Additional file 1 of Study protocol: a cluster randomized trial to evaluate the effectiveness and implementation of onsite GeneXpert testing at community health centers in Uganda (XPEL-TB)

Tania F. Reza, , Katherine Farr, Mariam Nantale, Denis Oyuku, Annet Nakaweesa, Johnson Musinguzi, , Priya B. Shete, Austin Tucker, Olivia Ferguson, Katherine Fielding, , David Dowdy, David A. J. Moore, , Sara L. Ackerman, Margaret A. Handley, &
Additional file 1. Summaries of specific process changes made at each site.

Additional file 2 of Study protocol: a cluster randomized trial to evaluate the effectiveness and implementation of onsite GeneXpert testing at community health centers in Uganda (XPEL-TB)

Tania F. Reza, , Katherine Farr, Mariam Nantale, Denis Oyuku, Annet Nakaweesa, Johnson Musinguzi, , Priya B. Shete, Austin Tucker, Olivia Ferguson, Katherine Fielding, , David Dowdy, David A. J. Moore, , Sara L. Ackerman, Margaret A. Handley, &
Additional file :. Details on the rationale for and implications of changing the primary outcome from a proportion to a count.

Additional file 1 of Hippocampal granule cell dispersion: a non-specific finding in pediatric patients with no history of seizures

, Kathleen J. Millen & Raj P. Kapur
Additional file 1.Supplementary Tables and Figures.Supplementary Table 1: List of patients evaluated with immunohistochemistry/immunofluorescence; Supplementary Table 2: List of seizure patients and controls in published reports of GCD; Supplementary Fig. 1: Control hippocampi demonstrate variable severities of GCD; Supplementary Fig. 2: GCD occurs independent of different clinical parameters in patients with or without epileptic history; Supplementary Fig. 3: Distribution of neural progenitors is similar in cadaveric controls and seizure cases with GCD; Supplementary Fig. 4:...

Pro-inflammatory effects of crystalline- and nano-sized non-crystalline silica particles in a 3D alveolar model

Tonje Skuland, Marit Låg, Arno C. Gutleb, Bendik C. Brinchmann, Tommaso Serchi, Johan Øvrevik, Jørn A. Holme & Magne Refsnes
Abstract Background Silica nanoparticles (SiNPs) are among the most widely manufactured and used nanoparticles. Concerns about potential health effects of SiNPs have therefore risen. Using a 3D tri-culture model of the alveolar lung barrier we examined effects of exposure to SiNPs (Si10) and crystalline silica (quartz; Min-U-Sil) in the apical compartment consisting of human alveolar epithelial A549 cells and THP-1-derived macrophages, as well as in the basolateral compartment with Ea.hy926 endothelial cells. Inflammation-related responses were...

Use of buffer methods to estimate the potential acidity of Mato Grosso soils

Marcelo Ribeiro Vilela Prado, Milton Ferreira De Moraes, , Carlos Leandro Rodrigues Do Santos, David Vilas Boas De Campos &
ABSTRACT Mato Grosso, with a total area of 903357 km², does not have an official methodology for estimating soil potential acidity (H + Al), and determination of H + Al using the standard method is onerous and time consuming. The objective of this study was to compare estimated values of H + Al determined using the standard calcium acetate method with those obtained using three buffer methods, namely, the Shoemaker, McLean, and Pratt (SMP) buffer,...

The scope of tobacco cessation randomized controlled trials in low- to middle-income countries: protocol for a scoping review

Navin Kumar, Jessica Ainooson, , Grace Chen, Lauren Cueto, Kamila Janmohamed, Jeannette Jiang, Raymond Niaura & Amy Zhang
Abstract Background Tobacco consumption is the leading cause of preventable death globally. The global mortality burden of tobacco use lies predominantly in low- to middle-income countries (LMICs). There is much evidence on the effectiveness of tobacco cessation RCTs in high-income nations. However, the evidence base in LMICs is far more limited. To effectively design randomized controlled trials (RCTs) that mitigate tobacco-related harms in LMICs, further understanding of RCTs in this environment will be helpful. We...

Creole bean seeds microbiolization with doses of Trichoderma harzianum

, Brenda Tortelli, Francine Spitza Stefanski, , Vanessa Neumann Silva & Paola Mendes Milanesi
ABSTRACT: In the search for improved yields, seed treatment by microbiolization has been used as an alternative to chemical treatment. The objective was to verify the physiological and sanitary quality of creole bean seeds, var. Chumbinho, after microbiolization with doses of a commercial product (c.p.) with Trichoderma harzianum (strain ESALQ-1306). The treatments were: T1) 100 mL c.p./100 kg seeds; T2) 150 mL c.p.; T3) 200 mL c.p.; T4) 200 mL of chemical treatment (c.p., 250...

Transcriptome analysis identifies genes and co-expression networks underlying heat tolerance in pigs

, Christian Maltecca, Francesco Tiezzi, Emmanuel Lozada Soto & William L. Flowers
Abstract Background Heat stress adversely affects pig growth and reproduction performance by reducing feed intake, weight gain, farrowing rate, and litter size. Heat tolerance is an important characteristic in pigs, allowing them to mitigate the negative effects of heat stress on their physiological activities. Yet, genetic variation and signaling pathways associated with the biological processes of heat-tolerant pigs are currently not fully understood. This study examined differentially expressed genes and constructed gene co-expression networks on...

Emissions and health risks from the use of 3D printers in an occupational setting

Felix L Chan, , Susan M Tarlo, Nikhil Rajaram & Ronald House
The aim of this study was to determine concentrations of particulates and volatile organic compounds (VOCs) emitted from 3D printers using polylactic acid (PLA) filaments at a university workroom to assess exposure and health risks in an occupational setting. Under typical-case (one printer) and worst-case (three printers operating simultaneously) scenarios, particulate concentration (total and respirable), VOCs and formaldehyde were measured. Air samples were collected in the printing room and adjacent hallway. Size-resolved levels of nano-diameter...

Effects of addition of engineered ZnO nanoparticles on the stability of colloidal suspensions containing TiO2 interacting with sandy soil

Elizabeth Mendes De Oliveira, , Cintia De Faria Ferreira Carraro, Mara Carolina Do Carmo Paresque & Jose Adilson De Castro
Abstract The stability of colloidal suspensions of engineered nanoparticles in the environment is of great interest for the risk assessment and treatment of hazardous materials. The relevance of this study is due to the evidence that engineered nanoparticles have been produced and used in commercial products in large scale, especially ZnO and TiO2, which are transported through the environmental components interacting with soil and water, representing the high potential impact on the ecosystems. In this...

Guidance on Safeguarding in International Development Research

Leona Vaughn, Linnea Renton, Alex Balch, Surekha Garimella, & Adriana Smith
UKCDR Guidance for all involved in the delivery of international research

LocalView

Manage Your Google My Business Listing and Online ReviewsGet more customer reviews, be found online,
attract new customers – easily and effectively.https://localview.co/

iFit Spectra

Ben Esse
Dataset of spectra supporting iFit manuscript

Factors influencing side air curtain deployment in rollover motor vehicle accidents

Jacob Ristow, Minal Cordeiro, Daniel Boyle, Paul Telehowski & Theresa Atkinson
Objective: Recent changes in FMVSS have led to the utilization of side air curtains to provide occupant retention during rollover events. However, the safety advantage provided by the air curtains relies on the vehicle system’s ability to detect the rollover event and deploy the curtains. The purpose of this study is to identify crash and vehicle characteristics in motor vehicle rollovers that influence side air curtain deployment and occupant outcomes. The current study aims to...

Kory et al example

Jordan Bryan
Data corresponding to the Kory et al. example

Metadata record for: Global hydro-environmental sub-basin and river reach characteristics at high spatial resolution

Simon Linke, Bernhard Lehner, Camille Ouellet Dallaire, Joseph Ariwi, Günther Grill, Mira Anand, Penny Beames, Vicente Burchard-Levine, Sally Maxwell, Hana Moidu, Florence Tan & Michele Thieme
This dataset contains key characteristics about the data described in the Data Descriptor Global hydro-environmental sub-basin and river reach characteristics at high spatial resolution.
Contents:
1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format

Versioning Note:Version 2 was generated when the metadata format was updated from JSON to JSON-LD. This was an automatic process that changed only the format, not the contents, of...

Understanding the impact of road design characteristic on teen driver’s fatality

Woon Kim, &
Objective: There is little research simultaneously examining both teen drivers’ characteristics and the driving environment. This study aimed to investigate how traffic engineering factors (road designs, traffic operations, and surface conditions) contribute to risks of teen driver’s fatality. Understanding the role of traffic engineering factors can further improve efforts to reduce teen diving-related fatal crashes. Methods: This study used the Fatality Analysis Reporting System and General Estimate System for years 2014 to 2015. We explored...

Understanding the impact of road design characteristic on teen driver’s fatality

Woon Kim, &
Objective: There is little research simultaneously examining both teen drivers’ characteristics and the driving environment. This study aimed to investigate how traffic engineering factors (road designs, traffic operations, and surface conditions) contribute to risks of teen driver’s fatality. Understanding the role of traffic engineering factors can further improve efforts to reduce teen diving-related fatal crashes. Methods: This study used the Fatality Analysis Reporting System and General Estimate System for years 2014 to 2015. We explored...

Dataset for: \"T-Cycle EPR: Development at 275 GHz for the study of reaction kinetics & intermediates.\"

Gabriele Panarelli
This dataset contains all the data used for my PhD thesis at Leiden University:- raw data (spectra, time traces)- Python files for data analysis
All the experimental details are mentioned in great detail in my thesis, available in the link provided.

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