584,688 Works

Using Score Equating and Measurement Invariance to Examine the Flynn Effect in the Wechsler Adult Intelligence Scale

Nicholas Benson, & Gordon E. Taub
The Flynn effect (FE; i.e., increase in mean IQ scores over time) is commonly viewed as reflecting population shifts in intelligence, despite the fact that most FE studies have not investigated the assumption of score comparability. Consequently, the extent to which these mean differences in IQ scores reflect population shifts in cognitive abilities versus changes in the instruments used to measure these abilities is unclear. In this study, we used modern psychometric tools to examine...

Wobble↔Watson-Crick tautomeric transitions in the homo-purine DNA mismatches: a key to the intimate mechanisms of the spontaneous transversions

& Dmytro M. Hovorun
The intrinsic capability of the homo-purine DNA base mispairs to perform wobble↔Watson–Crick/Topal–Fresco tautomeric transitions via the sequential intrapair double proton transfer was discovered for the first time using QM (MP2/DFT) and QTAIM methodologies that are crucial for understanding the microstructural mechanisms of the spontaneous transversions.

Synthesis of Novel Spiro[indol-2,2′-pyrroles] Using Isocyanide-Based Multicomponent Reaction

, , , Tetsuji Moriguchi & Akihiko Tsuge
An efficient and facile method for the synthesis of novel spiro[indole-2,2′-pyrroles] from N-methyl-3-isatin imines, t-butyl isocyanide, and dialkyl acetylenedicarboxylate has been achieved by [3 + 2] cyclo addition reaction. All the products were purified by column chromatography as yellow solids and confirmed with 1H NMR, 13C NMR, fast atom bombardment, mass, and infrared. Compound 11 was further confirmed with x-ray analysis.

Introduction to Methodology Framework towards Water Quality Assessment. Case Study: A Review of Malacca River

Ang Kean Hua &
Water is a basic resources required by organisms for survival. Various activities have caused water quality to remain contaminated. These problems are present in the Malacca River, Malacca state. This research study has been carried out based on methodology framework review towards water quality assessment in Malacca River. Methodology can be divided into three processes, namely the planning process, applying process, and analyzing process. The planning process includes the design to collect and gather, analyze,...

Palladium, Gold, and Gold–Palladium Nanoparticle-Supported Carbon Materials for Cyclohexane Oxidation

, & Sang Wook Kim
Transition metal supported porous carbon materials have become a promising aspirant in energy storage, solid catalysis, and material chemistry. Palladium, gold, and gold–palladium anchored carbon composites (CPC-25/170, CGC-25/170, and CGPC-25/170) with two different sized carbon cages (∼25 and 170 nm) were constructed using nano-silica ball (NSB) as the template and a pyrolysis fuel oil (PFO) based pitch residue as the carbon source. The Pd, Au, and Au–Pd doped carbon nanoreactors were characterized by various physicochemical...

Molecular insight into amyloid oligomer destabilizing mechanism of flavonoid derivative 2-(4′ benzyloxyphenyl)-3-hydroxy-chromen-4-one through docking and molecular dynamics simulations

, Swati Srivastava, , Sandeep Kumar Singh, & Ashok Sharma
Aggregation of amyloid peptide (Aβ) has been shown to be directly related to progression of Alzheimer’s disease (AD). Aβ is neurotoxic and its deposition and aggregation ultimately lead to cell death. In our previous work, we reported flavonoid derivative (compound 1) showing promising result in transgenic AD model of Drosophila. Compound 1 showed prevention of Aβ-induced neurotoxicity and neuroprotective efficacy in Drosophila system. However, mechanism of action of compound 1 and its effect on the...

An Efficient Synthesis of 1,2,3-Triazole Bridge-Connected Phosphonate Derivatives of Coumarin

Xu Li, , , Yang Liu, , &
GRAPHICAL ABSTRACT

Synthesis and Structure-Activity Relationship of N-(3-Oxo-1-Thia-4-Azaspiro[4.5]Decan-4-Yl)Carboxamide Inhibitors of Influenza Virus Hemagglutinin Mediated Fusion

Lieve Naesens, Füsun Göktaş, Evelien Vanderlinden, Zafer Cesur, Nesrin Cesur &
GRAPHICAL ABSTRACT

Работы Новгород-Северской экспедиции

Олександр Моця, &
Коваленко В.П., Куза А.В., Моця А.П. Работы Новгород-Северской экспедиции. /\ Археологические открытия 1982 года. М., Наука, 1984. - С. 272.

GIS Research UK (GISRUK) 2015 Proceedings

Nick Malleson, Nicholas Addis, Helen Durham, Alison Heppenstall, Robin Lovelace, Paul Norman & Rachel Oldroyd
This volume contains the papers presented at GIS Research UK 2015 (GISRUK2015) held at the School of Geography, University of Leeds, on 15-17 April 2015.

Modeling Gravitational Instabilities in Compact and Massive Protoplanetary Disks with Adaptive Mesh Refinement Techniques

Tim Lichtenberg
The astonishing diversity in the observed planetary population re- quires theoretical efforts and advances in planet formation theories. The use of numerical approaches provides a method to tackle the weaknesses of current models and is a major tool to slowly close gaps in poorly constrained areas such as the rapid formation of gi- ant planets in highly evolved systems. So far, most numerical approaches make use of Lagrangian-based smoothed-particle hydrodynamics (SPH) techniques or grid-based 2D...

Recruitment of seedlings versus ramets as affected by pasture degradation in alpine meadows and the implications for ecological restoration

, , , , , &
Background: The degradation of alpine meadows on the Qinghai-Tibetan Plateau (QTP) has an impact on vegetation recruitment from seedlings and ramets.Aims: Understanding the relative contribution of recruitment by seedling and ramet in alpine meadows is for the ecological restoration of degraded grasslands on the QTP.Methods: An experiment was conducted to investigate seedling and ramet densities, species composition and their relationships with standing vegetation in plots representative of non-degraded (ND), lightly (LD), moderately (MD) and severely...

Sensitivity of Head and Cervical Spine Injury Measures to Impact Factors Relevant to Rollover Crashes

, , , &
Objective: Serious head and cervical spine injuries have been shown to occur mostly independent of one another in pure rollover crashes. In an attempt to define a dynamic rollover crash test protocol that can replicate serious injuries to the head and cervical spine, it is important to understand the conditions that are likely to produce serious injuries to these 2 body regions. The objective of this research is to analyze the effect that impact factors...

Age-Dependent Factors Affecting Thoracic Response: A Finite Element Study Focused on Japanese Elderly Occupants

Jacobo Antona-Makoshi, Yoshihiro Yamamoto, Ryosuke Kato, Fusako Sato, Susumu Ejima, Yasuhiro Dokko & Tsuyoshi Yasuki
Objectives: The ultimate goal of this research is to reduce thoracic injuries due to traffic crashes, especially in the elderly. The specific objective is to develop and validate a full-body finite element model under 2 distinct settings that account for factors relevant for thoracic fragility of elderly: one setting representative of an average size male and one representative of an average size Japanese elderly male.Methods: A new thorax finite element model was developed from medical...

Effect of Aging on Brain Injury Prediction in Rotational Head Trauma—A Parameter Study with a Rat Finite Element Model

Jacobo Antona-Makoshi, Erik Eliasson, Johan Davidsson, Susumu Ejima &
Objective: The aim of this study was to investigate the possible effects of age-related intracranial changes on the potential outcome of diffuse axonal injuries and acute subdural hematoma under rotational head loading.Methods: A simulation-based parametric study was conducted using an updated and validated finite element model of a rat head. The validation included a comparison of predicted brain cortex sliding with respect to the skull. Further, model material properties were modified to account for aging;...

Census Study of Real-Life Near-Side Crashes with Modern Side Airbag-Equipped Vehicles in the United States

Cecilia Sunnevång, Bo Sui, Mats Lindkvist & Maria Krafft
Objective: This study aimed to investigate the crash characteristics, injury distribution, and injury mechanisms for Maximum Abbreviated Injury Score (MAIS) 2+ injured belted, near-side occupants in airbag-equipped modern vehicles. Furthermore, differences in injury distribution for senior occupants compared to non-senior occupants was investigated, as well as whether the near-side occupant injury risk to the head and thorax increases or decreases with a neighboring occupant.Method: National Automotive Sampling System's Crashworthiness Data System (NASS-CDS) data from 2000...

A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites

Esteban Rodríguez Arce, Cynthia Sarniguet, Tania S. Moraes, Marisol Vieites, , Andrea Medeiros, Marcelo A. Comini, Javier Varela, Hugo Cerecetto, Mercedes González, Fernanda Marques, , Lucía Otero & Dinorah Gambino
As part of our efforts to develop organometallic ruthenium compounds bearing activity on both trypanosomatid parasites and tumor cells, a new Ru(II)–cyclopentadienyl clotrimazole complex, [RuCp(PPh3)2(CTZ)](CF3SO3), where Cp = cyclopentadienyl, CTZ = clotrimazole, was synthesized and characterized. The compound was evaluated in vitro on T. cruzi (Y strain), the infective form of T. brucei brucei strain 427 (cell line 449), on three human tumor cell lines with different sensitivity to cisplatin (A2780, ovary; MCF7, breast; HeLa,...

Evaluation of infection type and inheritance of resistance to powdery mildew in two crosses in barley

Zahid Iqbal
In order to evaluate the gene number, gene effect and heritability to powdery mildew in barley Two resistant
cultivars were crossed with a susceptible cultivar. In a field study, the parents (P1, P2) and the generations (F1, F2
and F3) of two crosses were evaluated in a randomized complete block design with three replications. The
infection type of flag leaf and the whole plant was assessed in booting stage using Saari, E.E., and Prescott
method. The Scaling test indicated...

Law Enforcement and Water Resources of the Malacca River A Case Study of Public Perception

Ang Kean Hua
Malacca state is a historical tourism based economy, and has been recognized by UNESCO as a world heritage site. However, Malacca River pollution can be attributed to human activities such as agriculture, livestock, factories, commercial, and settlements. So, this research study has been conducted to determine the effectiveness of law enforcement of water resources in the Malacca River. The research involves a quantitative approach, which is a questionnaire divided into two parts. Part A is...

Evaluation of photoperiod and thermosensitive genic male sterile lines for hybrid rice seeds production in Kenya

Zahid Iqbal
Photo–thermo-sensitive genic male sterile (P(T)GMS) rice is a new hybrid rice technology that uses prolonged
light length and high temperatures to induce sterility. This technology is being introduced in Kenya but such
growth conditions are lacking in the tropics. To overcome this, we grew P(T)GMS under greenhouse conditions
where day light length was prolonged to 14 hrs using solar illumination and day and night temperatures were
maintained above 36Cº and 24ºC respectively. Sterility of P(T)GMS was determined by the...

Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood

Arko Sen, Pablo Cingolani, , Susan Land, Adriana Mercado-Garcia, Martha M Tellez-Rojo, Andrea A Baccarelli, Robert O Wright & Douglas M Ruden
Prenatal exposure to neurotoxicants such as lead (Pb) may cause stable changes in the DNA methylation (5mC) profile of the fetal genome. However, few studies have examined its effect on the DNA de-methylation pathway, specifically the dynamic changes of the 5-hydroxymethylcytosine (5hmC) profile. Therefore, in this study, we investigate the relationship between Pb exposure and 5mC and 5hmC modifications during early development. To study the changes in the 5hmC profile, we use a novel modification...

Pro-environmental Practices among Malaysian Construction Practitioners

Mohammad Iranmanesh, &
Societal interest and alarm in Malaysia is growing due to the substantial environmental impacts caused by considerable amounts of construction waste and energy consumption. Malaysian citizens are becoming increasingly concerned about how these impacts will affect their local communities and therefore are ever more attentive to the construction industry’s efforts to reduce waste and energy consumption. The aim of the present study is to measure the current status of the pro-environmental practices among construction industry...

Quality Control for Environmental Policy Appraisal Tools: An Empirical Investigation of Relations Between Quality, Quality Control and Effectiveness

Ivar Lyhne, Matthew Cashmore, Hens Runhaar & Frank Van Laerhoven
The spectre of regulatory reform carried out in a range of Western countries has generated concern amongst parts of the environmental policy community. Quality and effectiveness are said to be at stake, but empirically there is a dearth of data on the relationship between provisions for quality control and the effects on quality and effectiveness. This research addresses this lacuna by analysing the effects of different quality control provisions in the Netherlands and Denmark for...

Building the capacity for forecasting marine biogeochemistry and ecosystems: recent advances and future developments

, , , , , , , , , , , , &
Building the capacity for monitoring and forecasting marine biogeochemistry and ecosystem dynamics is a scientific challenge of strategic importance in the context of rapid environmental change and growing public awareness of its potential impacts on marine ecosystems and resources. National Operational Oceanography centres have started to take up this challenge by integrating biogeochemistry in operational systems. Ongoing activities are illustrated in this paper by presenting examples of (pre-)operational biogeochemical systems active in Europe and North...

In silico Spleen Tyrosine Kinase Inhibitor Screening by ChooseLD

Hideaki Umeyama, Mitsuo Iwadate & Y-H. Taguchi
IPSJ Transactions on Bioinformatics Vol. 8 (2015) pp. 14-20

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