122 Works
Design, synthesis and biological characteristics of pyrazolo[3,4-d]pyrimidine derivatives as potential VEGFR-2 inhibitors - Supporting Information
Dan-Xia Ying, Ju Wang, Xiu-Fang Li, Wen Zhang & Guo-Wu Rao
Supplementary: The 1H-NMR, 13C-NMR and MS data of synthesized compounds I-1 to 6. Supplementary 1: I-1 Supplementary: The 1H-NMR, 13C-NMR and MS data of synthesized compounds Ⅱ-1 to 6. Supplementary 7: II-1
Japanese translation of: Plain language summary of results from the JAVELIN Bladder 100 study: avelumab maintenance treatment for advanced urothelial cancer
Petros Grivas, John A. Blake-Haskins, Nuno Costa, Bo Huang, Robert J. Laliberte, Daniel P. Petrylak, Jeanny B. Aragon-Ching, Joaquim Bellmunt, Cora N. Sternberg, Evgeny Kopyltsov, Norihiko Tsuchiya, Srikala S. Sridhar, Yohann Loriot, Anders Ullén, Wim Demey, Sinisa Radulović, Haralabos Kalofonos, Howard Gurney, Begoña P. Valderrama, Claudia Caserta, Eric Voog, Se-Hoon Park & Thomas Powles
Japanese translation of: Plain language summary of results from the JAVELIN Bladder 100 study: avelumab maintenance treatment for advanced urothelial cancer
Potent predictive CpG signature for temozolomide response in non-glioma-CpG island methylator phenotype glioblastomas with methylated MGMT promoter. Supplementary materials.
Ya-Long He, Anan Yin, Wei Lin, Bao-qiang Song, Kun Chen, Amandine Etcheverry, Yu-sha Ji, Yan Yao, Yi-feng Liu, Meng Zhang & Jiu Wang
Supplementary tables 1-7
Analysis on methylation and expression of PSMB8 and its correlation with immunity and immunotherapy in lung adenocarcinoma. Supplementary figures and tables.
Yuankai Shi, Puyuan Xing, Xiaohong Han, Ning Lou, Liling Huang, Guangyu Fan & Tongji Xie
Supplementary Figures 1-8 Supplementary Tables 1-13
Association of immune-related adverse events and efficacy in advanced non-small-cell lung cancer: a systematic review and meta-analysis. Supplementary materials.
Yuankai Shi, Ning Lou, Liling Huang, Yunxia Tao, Yu Feng, Le Tang, Haizhu Chen & Yu Zhou
Supplementary figures 1-12 Supplementary tables Prisma checklist
Association of immune-related adverse events and efficacy in advanced non-small-cell lung cancer: a systematic review and meta-analysis. Supplementary materials.
Yuankai Shi, Ning Lou, Liling Huang, Yunxia Tao, Yu Feng, Le Tang, Haizhu Chen & Yu Zhou
Supplementary figures 1-12 Supplementary tables Prisma checklist
Identification of the MALAT1/miR-106a-5p/ZNF148 feedback loop in regulating HaCaT cell proliferation, migration and apoptosis. Supplementary materials
Chi-Li Gong, Hui Wang, Hui-Zhen Liu, Bing-Hui Li, Cheng-Chen Zhang & Li-Wen Kuang
blood glucose. supplementary materials
Loop-mediated isothermal amplification assay in combination with lateral flow dipstick in HSV type 1: Supplementary figures
Fei Gao, Zhuoshi Wang, Mingqi Zhang, Yan Zhao, Tao Yao, Ling Xu, Xiangdong He, Bing Wang & Wei He
Aim: Diagnostic methods for HSV-1 need to be updated. Materials & methods: Serial dilutions of HSV- 1 DNA and ocular pathogenic microorganisms were tested by loop-mediated isothermal amplificationlateral flow dipstick assay (LAMP-LFD assay). The reliability of the LAMP-LFD assay and quantitative realtime PCR (qPCR) for HSV-1 detection was also validated using 30 clinical swab samples. Results: The LAMP reaction is optimal at 65◦C and 30 min. And the LAMP-LFD assay could detect HSV-1 up to...
German translation of the JAVELIN Bladder 100 study: avelumab maintenance treatment for advanced urothelial cancer
Petros Grivas, John A. Blake-Haskins, Nuno Costa, Bo Huang, Robert J. Laliberte, Daniel P. Petrylak, Jeanny B. Aragon-Ching, Joaquim Bellmunt, Cora N. Sternberg, Evgeny Kopyltsov, Norihiko Tsuchiya, Srikala S. Sridhar, Yohann Loriot, Anders Ullén, Wim Demey, Sinisa Radulović, Haralabos Kalofonos, Howard Gurney, Begoña P. Valderrama, Claudia Caserta, Eric Voog, Se-Hoon Park & Thomas Powles
German translation of the JAVELIN Bladder 100 study: avelumab maintenance treatment for advanced urothelial cancer
Plain language summary of results from the JAVELIN Bladder 100 study: avelumab maintenance treatment for advanced urothelial cancer. Spanish translation.
Petros Grivas, John A. Blake-Haskins, Nuno Costa, Bo Huang, Robert J. Laliberte, Daniel P. Petrylak, Jeanny B. Aragon-Ching, Joaquim Bellmunt, Cora N. Sternberg, Evgeny Kopyltsov, Norihiko Tsuchiya, Srikala S. Sridhar, Yohann Loriot, Anders Ullén, Wim Demey, Sinisa Radulović, Haralabos Kalofonos, Howard Gurney, Begoña P. Valderrama, Claudia Caserta, Eric Voog, Se-Hoon Park & Thomas Powles
Spanish translation of plain language summary of results from the JAVELIN Bladder 100 study
Influence of CYP3A5, IL-10 polymorphisms and metabolism rate on tacrolimus exposure in renal post-transplant recipients - Supplementary Material
Xi Cheng, Yuhao Chen, Lei Zhang, Biwen Chen, Dake Yang, Weihuang Chen, Pengli Zhu, Zhuo Fang & Zhaolin Chen.
Primers sequence of CYP3A5 and IL-10 Polymorphisms for PCR amplification.
Supplementary Table 3 - LRP1B as a potential gastric cancer biomarker
Ji Miao, Zhi Yang, Wen Guo, Lixiang Liu, Peng Song, Chao Ding & Wenxian Guan
Background: The aim of this study was to discover unique membrane proteins associated with gastric cancer (GC) in proteomics analysis. Methods: Using a data-independent acquisition strategy, we compared the relative expression levels of membrane proteins in GC. Results: A total of 2774 differentially expressed membrane proteins were identified between GC and normal cell lines. Conjoint analysis of transcriptomes and proteomes provided 11 potential biomarkers (GPRC5A, PSAT1, NUDCD1, RCC2, IPO4, FAM91A1, KANK2, PRADC1, NME4, METTL7A and...
Design and synthesis of selective FLT3 inhibitors via exploration of back pocket II - Supplementary material
Qing-Xin Wang, Yu-Hao Cao, Li-Jin Yang, Yi-Yuan Ma, Nan Li, Shi-Han Wu, Lu Chen, Jia-Zhen Wu, Zhen-Jiang Tong, Xiao-Long Wang, Xin Xue, Ning Ding, Xue-Jiao Leng, Liang Chang, Wei-Chen Dai, Yan-Cheng Yu, Shan-Liang Sun, Ye Yang, Nian-Guang Li & Zhi-Hao Shi
Supporting information Representative off-target/selective ligands Chemistry Compounds Information Side chains Target compounds 1H NMR and 13C NMR Spectra of Title Compounds
Table 1. Sequence identity (%, ATP binding site) between FLT3 and 328 other structural kinases that are gradually color-coded from green to orange to red. The ATP sites were defined according to KLIFS .
Table 2: Number of selective FLT3 inhibitors against 269 other kinases
Table 1. Sequence identity (%, ATP binding site) between FLT3 and 328 other structural kinases that are gradually color-coded from green to orange to red. The ATP sites were defined according to KLIFS .
Table 2: Number of selective FLT3 inhibitors against 269 other kinases
The synthesis and effects of a novel TRPC6 inhibitor, BP3112, on hepatocellular carcinoma - supplementary data
Ruizhi Qiao, Xin Fan, Lei Zhou, Dianchao Dong, Yang Liu, Detai Liu, Guangyuan Ma, Na Tang, Yubo Wang, Xiao-Qiang Li, Li Ren & Wei Cao
1. 1H and 13C NMR spectra of the hit compounds (3-12) 2. Experimental section of biological activity 13
Genetic variants of the Nrf2/ARE pathway on the risk of anti-tuberculosis drug-induced liver injury: a systematic review - supplementary material
Zhuolu Hao, Meiling Zhang, Xinyu Chen, Min Zhu, Bing Han, Yiwen He, Honggang Yi & Shaowen Tang
Table S1. Search strategies and results Table S2. Quality assessment of the included studies (NOS) Figure S1. Forest plot of AT-DILI risk associated with rs2001350 polymorphism in NFE2L2 of Nrf2/ARE pathway under different genetic model Figure S2. Forest plot of AT-DILI risk associated with rs6726395 polymorphism in NFE2L2 of Nrf2/ARE pathway under different genetic model Figure S3. Forest plot of AT-DILI risk associated with rs2070401 polymorphism in BACH1 of Nrf2/ARE pathway under different genetic model...
Virtual screening identifies tipranavir as a SIRT1 inhibitor with anti-hepatocarcinoma effect - Supplementary files.docx
Yan Shen, Qingyu Zhang, Lu Zhang, Juan Wang, Mao Shu, Kuilong Huang, Yong Hu & Zhihua Lin
Supplementary Table 1. Key resources table of antibodies, chemicals and assay kits Figure S1. Time evolution plot of root mean square deviation (RMSD) of compound 6148 (black) and SIRT1-6148 complex (red). Figure S2. Time evolution plot of root mean square deviation (RMSD) of compound 974 (black) and SIRT1-974 complex (red) Figure S3. Time evolution plot of root mean square deviation (RMSD) of compound 952 (black) and SIRT1-952 complex (red) Figure S4. Time evolution plot of...
Effective personalized neoantigen vaccine plus anti-PD-1 in a PD-1 blockade-resistant lung cancer patient. Supplementary Tables
Qing Xu, Li Yang, Xu Dan, Heng Xu, Yuquan Wei, Huanlong Qin, Zhuqing Liu, Yu Zhao, Juemin Fang, Zhongzheng Zhu, Jiaqiang Wang & Song Gao
Supplementary Table 1. Neoantigens predicted and selected in this study. Supplementary Table 2. Significant expanded TCR clones specific to neoantigens
Low-dose 5-aza-2′-deoxycytidine protects against early renal injury by increasing klotho expression. Supplementary table
Hang Li, Yiying Wu, Lei Xu, Wenjing Wang, Xinli Xu, Xiaorong Zeng & Yanlong Zhao
Supplementary table
Long-term response to sintilimab, bevacizumab and chemotherapy in heavily pretreated microsatellite stable colon cancer. Supplementary Figure.
Quanli Han, Beifang Niu, Sheng Liu, Erhong Meng, Muhong Deng, Qi Wang & Zhi Cui
Supplmentary figure 1
Integrative analysis of a novel 5 methylated snoRNA genes prognostic signature in patients with glioma
Bing Zhao, Erbao Bian, Deran Zhang, Zhiwei Wang, Yu Wang, Zhigang Cheng, Zhihao Yang, Lianxin Li, Yinfei Zheng & Xiaoyu Yue
Supplementary Table 1 | Genes associated with risk scores.
Supplementary Table 2 | Expression levels and methylation levels of SNORA71B in gliomas (TCGA Database). Supplementary Table 3 | Fold change values of the 5 methylated snoRNA genes (TCGA Database).
Supplementary Table 4 | Methylation levels of five snoRNAs in gliomas (TCGA Database).
Supplementary Table 5 Clinic-pathological characteristics of 13 glioma patients.
Supplementary Table 2 | Expression levels and methylation levels of SNORA71B in gliomas (TCGA Database). Supplementary Table 3 | Fold change values of the 5 methylated snoRNA genes (TCGA Database).
Supplementary Table 4 | Methylation levels of five snoRNAs in gliomas (TCGA Database).
Supplementary Table 5 Clinic-pathological characteristics of 13 glioma patients.
Arabic translation
Petros Grivas, John A. Blake-Haskins, Nuno Costa, Bo Huang, Robert J. Laliberte, Daniel P. Petrylak, Jeanny B. Aragon-Ching, Joaquim Bellmunt, Cora N. Sternberg, Evgeny Kopyltsov, Norihiko Tsuchiya, Srikala S. Sridhar, Yohann Loriot, Anders Ullén, Wim Demey, Sinisa Radulović, Haralabos Kalofonos, Howard Gurney, Begoña P. Valderrama, Claudia Caserta, Eric Voog, Se Hoon Park & Thomas Powles
Arabic translation of the JAVELIN Bladder 100 study: avelumab maintenance treatment for advanced urothelial cancer
Synthesis and anti-ovarian cancer effects of benzimidazole-2-substituted pyridine and phenyl propenone derivatives - Supplementary Information.docx
A-Long Cui, Zi-ying Zhou, Ya-Li Wang, Lin-Tao Wu, Si-Tu Xue & Zhuo-Rong Li
13C NMR and 1H NMR mass spectrometry data for compounds A-1 to A-10.
Current knowledge and future perspectives on exosomes in the field of regenerative medicine: a bibliometric analysis. Supplementary figures and tables.
Lianbo Zhang, Yiming Hu, Yu Chen & Yuxuan Dai
Supplementary figure 1 Co-cited journals analysis picture Supplementary figure 2 Network visualization map of co-cited references Supplementary figure 3 Keyword co-occurrence analysis picture Supplementary figure 4 Timing analysis of keywords co-occurrence Supplementary figure 5 Density map of analysis of keyword co-occurrence
Supplementary tables 1-5
Supplementary tables 1-5
Bladder cancer diagnosis with a four-miRNA panel in serum Supplementary Figure 1
Xinji Li, Wenkang Chen, Rongkang Li, Xuan Chen, Guocheng Huang, Chong Lu, Zhenyu Wen, Xiqi Peng, Kaihao Liu, Chunduo Zhang, Hang Li, Yimin Hu, Zhengping Zhao, Lingzhi Tao & Yongqing Lai
Bladder cancer diagnosis with a four-miRNA panel in serum Supplementary Figure 1
Loop-mediated isothermal amplification assay in combination with lateral flow dipstick in HSV type 1: Supplementary figures
Fei Gao, Zhuoshi Wang, Mingqi Zhang, Yan Zhao, Tao Yao, Ling Xu, Xiangdong He, Bing Wang & Wei He
Aim: Diagnostic methods for HSV-1 need to be updated. Materials & methods: Serial dilutions of HSV- 1 DNA and ocular pathogenic microorganisms were tested by loop-mediated isothermal amplificationlateral flow dipstick assay (LAMP-LFD assay). The reliability of the LAMP-LFD assay and quantitative realtime PCR (qPCR) for HSV-1 detection was also validated using 30 clinical swab samples. Results: The LAMP reaction is optimal at 65◦C and 30 min. And the LAMP-LFD assay could detect HSV-1 up to...
Affiliations
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Chinese Academy of Medical Sciences & Peking Union Medical College122
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Huazhong University of Science and Technology70
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Zhejiang University68
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Chongqing Medical University48
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Shanghai Jiao Tong University48
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Chinese Academy of Sciences44
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Fudan University42
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Capital Medical University42
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Nanjing Medical University39
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Central South University31