This is the study of effects of FPMINT derivative on cell viability, Western Blot on ENT1 and ENT2 protein expression, uridine uptake of concentration dependence, kinetics and reversibility.

A collection of HKU library course materials to help users develop their information literacy and research skills.

Through the workshop, you will learn to use Find@HKUL.Find@HKUL: provides a one-stop search platform for HKUL collection.We will cover:Simple SearchAdvanced SearchTroubleshooting

Student Startup Kit @ HKUL (via Zoom) 2020
Through this workshop, you will learn how to configure and install the essential software and Apps to facilitate your workflow, including:
Mobile@HKUL: Quick mobile access to HKU library information and services. Reload via HKUL: A bookmarklet to facilitate access to HKUL subscribed resources from a publisher website. HKUL Search Assistant: a plugin to search HKU Libraries Catalogue and other popular databases within your browser and access HKUL...

For the potential applications in ferroelectric switching and piezoelectric nano-generator device, the promising ferroelectric properties of two dimensional (2D) layered In2Se3 attracted much attention. In the present study, 2D In2Se3 flakes down to monolayers are grown by chemical vapor deposition (CVD) technique on mica substrate with the structural, optical and ferroelectric properties being studied. The effect of growth parameter (time of growth and Ar flow rate) on the shape and size of the deposited flakes...

Hepatocellular carcinoma (HCC), the seventh most common malignancy in the world, can cause deaths of approximately 780,000 patients each year. Although a large number of studies have been conducted for a long time, the current treatment level of HCC is very limited, and many treatments are only effective for early HCC. However, most HCC are diagnosed in the advanced stage. Usually, patients with advanced stage have extrahepatic metastasis. This metastasis is not a random process....

Hepatocellular carcinoma (HCC) is the sixth most common cancer and the fourth leading cause of cancer-related death globally. Hepatitis B virus (HBV) and hepatitis C virus (HCV) infection are the major risk factors accounting for 75% of all HCC cases. Currently, curative treatments including surgical resection and liver transplantation can only be applied to early diagnosed patients. For advanced HCC patients, the currently available first-line molecularly targeted medications showed limited survival benefits and low response...

SDSS J1038+4849 lens models

SDSS J1038+4849 lens models

Diabetic Nephropathy (DN), one of the most common microvascular complication of diabetes, is a serious public health concern all over the world. Long non-coding RNAs (lncRNAs) are more than 200 nucleotides in length and play roles in various biological pathways, such as inflammation, cell senesce and apoptosis. On this basis, my research direction is about to explore the role of lncRNA Nuclear Enriched Abundant Transcript 1 (NEAT1) in diabetic nephropathy and to find new therapeutic...

ORCID integration in the Scholars Hub and DataHub

Thesis: Trace-elements in ostracods as proxy of envrionmental parameters in shallow marine waters Pictures obtained though a Zeiss microscope 305. Magnification 4X.Species: Neomonoceratina delicata and Sinocytheridea impressa

The human H3N2 influenza viruses was introduced into the human population in 1968 as a novel pandemic virus that emerged through genetic reassortment between human H2N2 and avian influenza virus of H3 subtype. A switch in receptor binding specificity is a critical step for influenza interspecies transmission, as avian influenza viruses typically recognize alpha 2, 3-linked sialiosides while human influenza viruses recognize alpha 2,6-linked sialosides. Further, the receptor binding domain (RBD) that mediates binding to...

Breastfeeding provides optimal nutrients for infants and is one of the most important public health issues. Globally, breastfeeding initiation rates are high with around 95% of all infants receiving some breastmilk. Over the past two decades, the mode of breastfeeding has been evolving and an increasing number of mothers are now choosing to feed their infant by expressed breast milk rather than directly at the breast. However, only few recent studies have described the rates...

Hepatocellular carcinoma (HCC) is one of the deadliest cancers across the globe. Patients are usually diagnosed at advanced stage. Presence of microvascular metastasis, oversized tumor burden and insufficient liver remnant reduce the feasibility to surgical and local ablative treatment modalities. Besides, high propensity of tumor recurrence and metastasis increase the level of challenge in eliminating HCC. As a matter of fact, targeted therapy confers survival benefits to HCC patients in late phase. In this regard,...

This dataset contains the supporting data and/or raw data for the results present in this MPhil thesis, signed data management plan submitted in August 2019 and a README text file describing each data file.

The presentation slides about the Research Data Management workflow, DMP tool and Data repository for the new RPg students in the University of Hong Kong.

Dataset includes raw data and analyses of Western blot and qPCR, pictures of HE, PAS and IHC and summary file of graphs produced during the project.

This data set includes data sets and brief protocols of experiments performed by me. The data include 1. FACS results from ZIKV-infected HMC3 of MHC and functional markers' expressions (also including plaque assay results)2. FACS results from ZIKV-infected U251 of MHC-I (also including plaque assay results)3. Cytokine and growth factor bead-based multiplex results of ZIKV-infected HMC34. FACS results of intracellular staining of MHC-I of ZIKV-infected HMC3 and effect of MG132 proteosomal inhibition5. FACS results from...

This dataset includes all the raw and processed data of immunohistochemistry, RNA-sequencing, functional assay, flow cytometry, quantitative-PCR and Western blotting included in the MPhil thesis.

Pharmaceutical reactivation of lytic cycle of Epstein–Barr virus (EBV) represents a potential therapeutic strategy against EBV-associated epithelial malignancies, e.g., gastric carcinoma (GC) and nasopharyngeal carcinoma (NPC). A novel lytic-inducing compound, C7, which exhibits structural similarity to Di-2-Pyridyl Ketone 4, 4-Dimethyl-3-Thiosemicarbazone (Dp44mT), a known chelator of intracellular iron, is found to reactivate EBV lytic cycle in GC and NPC. This study aims to delineate the mode of action of C7 and clinically available iron chelators in...

Following spinal cord injury, the majority of macrophages are polarised to the pro-inflammatory M1 phenotype, contributing to secondary injury. This study aims to find ways to manipulate macrophage polarisation to the M2 phenotype to facilitate recovery from spinal cord injury. Dataset includes Western blot analysis, RT-PCR, IHC and ICC experiments from animal and cell culture models.

In the recent years, different forms of new technologies, such as robots and artificial intelligence, have entered into our lives. Although behavioral scientists have started to investigate this phenomena, scholarly research in this field is still at an early stage. This thesis aims to advance our understanding on human interaction with technologies in business contexts. Prior work has suggested the benefits of equipping robots with humanlike features in non-competitive contexts. Extending this, essay 1 examines...

The dataset recorded the air pressure of the robotic glove during training of each participates.

A collection of HKU library course materials to help users develop their information literacy and research skills.