Long noncoding RNAs play crucial roles in every stage of gene regulation, from gene transcription to translation to cell signaling. The dysregulation of lncRNAs has been associated with cancer progression. This study aims to identify oncogenic lncRNAs in hepatocellular carcinoma by using different molecular approaches and cutting-edge screening approach.
This dataset contains the supporting data of in vitro and in vivo assays as well as the summary of sequencing data.
Please refer to the README file for...

Postgraduate Library Workshop 2022

Through the workshop, you will be able to: Identify and access the resources to put up a literature review Master the basic search skills to find pertinent information Set up alerts to keep updated on latest research Configure or install applications to facilitate learning and research Recognize the importance of academic integrity through ethical use of information and research data managementIdentify the library services and facilities in support of your research cycle,...

This report explores a learning and self-improvement platform named Transformation, which utilizes current and emerging technologies to augment online learning. Qualitative research with existing data is applied for this Case Study Project Report. Transformation plans to engage in the market space by networking learners with content providers, combining technologies in IoT, Big Data, AI and neurosciences to revolutionize learning and self-improvement, creating new thinking, products, businesses and consumer behaviors along the way.
To provide background and...

Endnote 20 is a citation management software and the HKU site license covers current HKU staff and students.
Through this workshop, you will learn how to: Create an EndNote 20 library Build your Endnote 20 library by exporting citations from FIND@HKUL, Academic Search Complete and Google Scholar Create in-text citations and reference list in Word document using Cite While You WriteManage EndNote 20 library by creating groups

This Guideline is one of the deliverables of the project on Enhancing Learning Experience for Students with Visual Impairment in Higher Education. It is a compilation of recommended practices that promote an accessible and inclusive teaching and learning environment for students with disabilities at higher education institutions. Sources of information included a review of websites of 76 local and international higher education institutions, focus group interviews, external review, as well as research team members’ input....

Endnote 20 is a citation management software and the HKU site license covers current HKU staff and students.
Through this workshop, you will learn how to: Create an EndNote 20 library Build your Endnote 20 library by exporting citations from FIND@HKUL, Academic Search Complete and Google Scholar Create in-text citations and reference list in Word document using Cite While You Write Manage EndNote 20 library by creating groups

This dataset includes riverine carbon concentrations and dissolved greenhouse gas concentrations and emissions measured in the Jing River catchment on Chinese Loess Plateau. Detailed information is provided in the 'README' file.

Initiated by the Chinese president Xi Jinping in 2013, the Belt and Road initiative (BRI) is a multi-trillion-dollar agenda for facilitating trade and investment, especially massive infrastructural developments. In recent years, discussions around the BRI have been increasing as more than 130 countries and 30 international organizations have officially joined the initiative, collaborating in a series of transnational infrastructure projects funded by Chinese companies or the Chinese state. This dataset provides 500,711 posts and 714,794...

The datasets consist of six sets respectively collected to (1) assess the frequency, location, and morphology of accessory maxillary sinus ostia, (2) assess location and dimensions of mucous retention cysts in the maxillary sinus, (3) assess the performance of a 3D convolutional neural network in automatic detection and segmentation of maxillary sinus lesions on CBCT images, (4) assess the bone graft volume needed for maxillary sinus floor elevation, (5) assess the frequency of and reasons...

Essential Library Services for HKU StaffThe workshop aims to familiarise HKU staff with the essential services to support their teaching and research. Topics cover:Part I: Information ResourcesFind information resources within and beyond HKU LibrariesAccess library electronic resources from Google Scholar and publisher’s websiteSet up alerts to stay updated with the latest researchPart II: Teaching SupportCreate online reading lists for your course teachingPurchase textbooks/resources through HKU LibrariesCopyright in teaching and learningPlagiarism and originality check with TurnitinPart...

Files associated with the thesis "Statistical Learning and Reading: Statistical Learning's Mechanism and Role in Dyslexia and Reading Development" by Stephen Man Kit LEE. File includes coded data for the meta-analysis of statistical learning in individuals with dyslexia. Published studies were retrieved from five bibliographic databases (i.e., MEDLINE, ERIC, PsycINFO, CINAHL and LLBA)while unpublished studies were from Open Access Theses and Dissertations (OATD). Keyword searches included, but were not limited, to implicit learning, procedural learning,...

Through the workshop, you will learn to use Find@HKUL.Find@HKUL: provides a one-stop search platform for HKUL collection.We will cover:Simple SearchAdvanced SearchTroubleshooting

This dataset includes petrological and geochemical data from ultramafic rocks sampled from the Isua supracrustal belt and the East Pilbara Terrane.

A total of 337 direct respiratory samples were collected during August 2020 to March 2021. All samples were tested with IS6110 real-time PCR and 76 samples tested with Ct values ranging 4.93 to 28.44 were selected for target amplicon sequencing, which covers 18 gene targets conferring anti-TB drug resistance. Target amplicon sequencing was performed using Illumina MiSeq on sample DNA purified and concentrated with our in-house validated protocol. Among the 76 selected samples, 69 of...

The supporting data are the original medical images and spreadsheets of patient information that included in my thesis.
This thesis explored and investigated several MRI techniques, and radiomics analysis based on multiparametric MRI in the clinicopathological assessment of cervical carcinoma (CC), specifically in discriminating between histological subtypes, tumour grades and FIGO stages.
1. Preliminary DKI study of CC (n=117) was conducted using 4 b-values of 0, 300, 1000 and 1500 s/mm2. The results demonstrated that...

This dataset includes the raw data and analysed data in the chapter 3 to chapter 7 of the thesis ''The regulation of integrin heterodimer organisation at the reticular adhesion'. The dataset here mainly investigates on the integrin-mediated reticular adhesion formation and cell migration, which enlarges the understanding of the reticular adhesions and integrin heterodimers. Dataset mainly includes images from TIRF and spinning-disk confocal microscopy and related analysis. The images analysis softwares like imageJ and Imaris...

The dataset contains the data for thesis " Functionalized Nanofibrous Scaffolds for Osteogenesis and Vascularization in Bone Tissue Engineering". The thesis aims to construct multifunctional scaffolds showing excellent potential in osteogenesis and vascularization in bone tissue engineering. Each chapter folder contains raw data and processed data used for the thesis. And supporting data for processed data are also provided.

The dataset contains the data for thesis "Two Essays on the Role of Contextual Factors in Digital Content Consumption". This thesis aims to examine the effectiveness of various platform designs by investigating the influence of different contextual factors on digital content consumption. Supporting data for the experimental studies in each chapter is provided in the folder.

A collection of HKU library course materials to help users develop their information literacy and research skills.

The spreadsheet contains data obtained in the physical experiments. The experiments are simulation of erosion of unsaturated soil beds caused by flow-type landslides. More specifically, these data are:
(1) Time-history of the basal forces generated by dry gravel flows measured by the loadcell. The loadcell is installed on the rigid bed.
(2) The probability distribution of basal forces generated by flows with different flow particle size.
(3) The probability distribution of basal forces generated by flows with different...

This PhD thesis first investigated the binding process of coronavirus spike proteins to the host cell receptors during virus entry. Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a novel cell surface binding target of MERS-CoV using the viral overlay protein binding assay (VOPBA). This finding was validated using multiple experimental assays including overexpression, siRNA knockdown, antibody blocking assay, and recombinant protein blocking assay.
Next, we further investigated on the pathogenic mechanism...

This dataset contains information regarding 15 interviews done with informants all personally known to the interviewer (the author) on their experience with and understanding of translation.
Folders A-C store background information and preparation work prior to the interviews; folders D-F are interview materials and raw data obtained from interviews – interview questions were either read to informants from a hardcopy of the interview script and question set in folder D in the interviewer’s hand or...

Endnote 20 is a citation management software and the HKU site license covers current HKU staff and students.
Through this workshop, you will learn how to: Create an EndNote 20 library Build your Endnote 20 library by exporting citations from FIND@HKUL, Academic Search Complete and Google Scholar Create in-text citations and reference list in Word document using Cite While You Write Manage EndNote 20 library by creating groups

Out laboratory has derived mEPSCs from mESCs, which represents a breakthrough in stem cell research. Unlike the standard pluripotent stem cells, mEPSCs can contribute to both embryonic and extra-embryonic lineages in the chimera assay (Yang et al., 2017a). In the development of EPSC culture conditions, many small molecules are tested to target an array of pathways involving early development. However, the mechanism of transiting from mouse ESCs to EPSCs is not fully dissected. In this...

The liver is the central organ for carbohydrate metabolism to maintain the blood glucose concentration within a normal range. Glucose breakdown or synthesis in the liver is tightly regulated by insulin via the insulin receptor (IR), insulin receptor substrate (IRS), phosphoinositide 3-kinase (PI3K), and protein kinase B (Akt) pathway to enhance glucose uptake and glycogen synthesis. Hence, people with insulin resistance have a higher possibility of developing type II diabetes mellitus (T2DM). To date, about...