234 Works

Aldosterone Regulation of Protein Kinase Signaling Pathways and Renal Na+ Transport by Non-genomic Mechanisms

Warren Thomas & Brian Harvey
Aldosterone is the key regulating hormone of whole-body fluid and electrolyte homeostasis. Perturbations in aldosterone synthesis and over-activation of the mineralocorticoid receptor (MR) can lead to excess salt reabsorption and hypertension. The cortical collecting duct (CCD) is the main site of action in the kidney for aldosterone regulation of whole-body sodium homeostasis through actions on the epithelial sodium channel (ENaC) and the Na/K-ATPase (Na/K pump). Aldosterone stimulates ENaC trafficking into the apical cell membranes in...

COLT: A New Weapon to Disseminate Knowledge

Bernard C. Rossier, Michelle Rossier & Jean-Pierre Kraehenbühl
Too few researchers receive adequate pre- or postgraduate training to conduct a rigorous scientific study. In the digital age, new tools are emerging, and the development of distance education could improve this worrying situation. In this context, Health Science e-Training (HSeT), a nonprofit Swiss foundation, has developed new pedagogical concepts and tools under customized online training (COLT). For the ADMIRE Cost network, we have used an article-based e-learning (ABL) tool that allowed the students to...

The Mental Health of Young People in Ireland: A report of the Psychiatric Epidemology Research across the Lifespan (PERL) Group

Mary Cannon, Helen Coughlan, Mary Clarke, Michelle Harley & Ian Kelleher
There is increasing concern about the mental health of young people in Ireland. Reports of psychological distress, substance abuse and suicide among Irish youths have become common. While we know that many young people in Ireland are experiencing mental distress, little research has been done to determine the actual number of young people who are experiencing a diagnosable mental disorder. This report goes some way towards addressing this issue by presenting findings from two research...

Pharmacy Education and Training in Ireland. The PHARMINE survey of European higher education institutions delivering pharmacy education & training - Ireland, 2010.

Judith Strawbridge, Lorraine Horgan, Christine Capdeville-Atkinson, Lea Noel & Jeffrey Atkinson
Pharmacy education is provided for in Ireland by three Higher Education Institutions; The Royal College of Surgeons in Ireland (RCSI), University of Dublin, Trinity College (TCD), and University College Cork (UCC). TCD was the sole provider of the undergraduate programme from 1977 until 2002 when the School of Pharmacy RCSI opened. The Schools educate approximately 150 students per annum. Applications to study pharmacy are far in excess of the places available as demand is high,...

Identification Of Environmental Variables For Use In Monitoring For The Evaluation Of The Rural Environment Protection Scheme – End of Project Report - 5190a

John Finn, Brendan P. Kavanagh & Maeve Flynn
The aim of this study was to identify and select quantitative environmental attributes for a monitoring programme that may be integrated into an environmental evaluation of Ireland’s agri-environmental scheme. This was achieved primarily by reviewing a range of agri-environmental indicators and suggesting indicators that would be appropriate for monitoring the REPS. The study conducted a desk review to collate information on current best practice in monitoring for environmental quality. A Project Group (comprising representatives from...

Irish Heart Foundation National Audit of Stroke Care

Frances Horgan, Anne Hickey, Hannah McGee & Desmond O'Neill
Stroke is the third leading cause of death and disability worldwide. It constitutes a formidable burden of disability for patients, their families, health professionals and the wider community. It combines aspects of both acute and chronic disease, and there is increasing evidence that those affected by stroke can benefit to a very significant extent from organised stroke care throughout the course of the illness. Delivering this care requires a unique combination of skills, drawing on...

Managing Complaints about Doctors: Stakeholder Perspectives of the Role of the Medical Council in Ireland

Siobhan McCarthy, Hannah McGee & Ciaran O'Boyle
This study has quantified the number of complaints made about doctors to hospitals in Ireland over a five year period. Complaints about doctors represented a minority of overall complaints to hospitals. They predominantly concerned clinical care and communication issues. There were few patient complaints about unprofessional behaviour. Hospitals rarely referred complaints to the Irish Medical Council. Thus current practice differs significantly from that envisaged in the new legislative framework. There is a need to promote...

The Social Inclusion of Older People at Local Level. Profiles of CDBs' Activities Addressing Older People

Sarah Delaney, Kevin Cullen & Petrina Duff
A companion resource to The Social Inclusion of Older People at Local Level: The Role and Contribution of CDBs

SLAN 2007: Survey of Lifestyle, Attitudes and Nutrition in Ireland. Alcohol use in Ireland: A profile of drinking patterns and alcohol-related harm from SLAN 2007.

Karen Morgan, Hannah McGee, Patrick Dicker, Ruairi Brugha, Mark Ward, Emer Shelley, Eric Van Lente, Janas Harrington, Margaret Barry, Ivan Perry & Dorothy Watson
The SLÁN 2007 survey contained a series of questions relating to alcohol use. These included questions about frequency (how often) an quantity (how much) of alcohol consumed, as well as questions about alcohol-related harm. Quantity of alcohol consumed was assessed by asking respondents how many standard drinks were taken, a ‘standard’ drink being defined as a half pint or a glass of beer, lager or cider; a single measure of spirits; a single glass of...

CPR 4 Schools Evaluation Study Report

Helen Burke, Karen Morgan & Hannah McGee
CPR 4 Schools is an ambitious training programme developed by the Irish Heart Foundation (IHF) to equip post-primary school students with cardiopulmonary resuscitation (CPR) skills. In the 2008–09 school year, a pilot of the programme was rolled out to 27,000 Transition Year students. The programme is one element of the IHF’s strategy to improve survival rates from sudden cardiac arrest, which causes an estimated 5,000 deaths in Ireland every year. Most of these deaths occur...

The Irish Study of Sexual Health and Relationships Main Report

Richard Layte, Hannah McGee, Amanda Quail, Kay Rundle, , Claire Donnelly, Fiona Mulcahy &
SEX and sexuality are core dimensions of the human experience and an important determinant of well-being. An individual’s sexual behaviour and sexual health cannot be separated from their social and cultural context. This is brought out in the World Health Organisation’s (WHO) definition of sexual health. It is concerned not just with the absence of disease or dysfunction but with a broad definition of health: “Sexual health requires a positive and respectful approach to sexuality...

Irish Contraception and Crisis Pregnancy [ICCP] Study. A Survey of the General Population.

Kay Rundle, Collette Leigh, Hannah McGee & Richard Layte
Crisis pregnancy is a complex challenge for individuals and societies alike. Its prevention and management need to be informed by up-to-date and locally applicable information on knowledge, attitudes and behaviours concerning sexual practices and contraception. Studies of aspects of sexual health in Ireland offer the prospect of vastly increasing our understanding of the pattern of health behaviours in the area of sexuality and their relationship to both the attitudes/beliefs and socio-demographic characteristics of individuals. Such...

Review of Health Services Available for Persons who Contracted Hepatitis C through the Administration within the State of Blood or Blood Products. Implementation of Recommendations.

Hannah McGee, Anne Hickey, Marie Brady & Katherine Gavin
the State of infected blood and blood products. The Report examines progress on the recommendations published in 2000, and recognizes the evolution in service needs since then with the addition of 4 new recommendations. The Report will assist health service providers, the Department of Health and Children and the support groups to continue working together to ensure that the future service needs of this Hepatitis C group are met. It is timely that this review...

The Irish Study of Sexual Health and relationships Sub-Report 2: Sexual Health Challenges and Related Service Provision

Hannah McGee, Kay Rundle, Claire Donnelly & Richard Layte
The ISSHR was commissioned by the Department of Health and Children and the Crisis Pregnancy Agency in response to a recommendation by the National AIDS Strategy Committee. It is the largest nationally representative study of sexual knowledge, attitudes and behaviour ever undertaken in Ireland. International evidence indicates that aspects of sexual health, such as contraception, crisis pregnancy and sexually transmitted infections, should be examined jointly. To this end, the Crisis Pregnancy Agency and the Department...

Pathways to child hospitalization : psychological, social and medical factors associated with the admission to hospital of children with gastroenteritis : a study of mothers and doctors.

Hannah McGee & Michael Fitzgerald
Gastroenteritis is a common self-limiting illness of childhood. Hospital treatment, except in severe cases, involves treatment which is the same as that given at home on medical advice or on parents' own knowledge. Nevertheless, in Ireland over 2,000 young children are hospitalized annually with this diagnosis. The objective of this study was to examine the reasons for the hospitalization of young children with gastroenteritis, with a view to decreasing the incidence of medically unnecessary admissions....

SLAN 2007: Suirbhe ar Nosanna Maireachtala, Dearcai agus Cothu in Eirinn: Priomhthuarascail

Karen Morgan, Hannah McGee, Dorothy Watson, Ivan Perry, Margaret Barry, Emer Shelley, Janas Harrington, Michal Molcho, Richard Layte, Nuala Tully, Eric Van Lente, Mark Ward, Jennifer Lutomski, & Ruairi Brugha
Is éard atá sa tuarascáil seo na príomhthorthaí ó Shuirbhé ar Nósanna Maireachtála, Dearcaí agus Cothú in Éirinn 2007 (SLÁN 2007). Is é seo an tríú suirbhé SLÁN agus an suirbhé is mó agus is é seo an chéad suirbhé a áirítear teangacha eile ann seachas Béarla agus Gaeilge. Rinneadh staidéir eile roimhe seo in 1998 (Friel et al, 1999) agus 2002 (Kelleher et al, 2003). Tá an dá thuarascáil seo le fáil ar an...

SLAN 2007: Survey of Lifestyle, Attitudes and Nutrition in Ireland. Dietary Habits of the Irish Population

Janas Harrington, Ivan Perry, Jennifer Lutomski, Karen Morgan, Hannah McGee, Emer Shelley, Dorothy Watson & Margaret Barry
The main SLÁN 2007 survey was conducted through face-to-face interviews. There were two sub-group studies involving (i) measurement of height, weight and waist circumference (subgroup of younger respondents) and (ii) a detailed physical examination (sub-group of older respondents). The overall aim was to provide nationally representative data on the general health, health behaviours and health service use of adults living in Ireland. The two sub-group studies aimed to provide vital information regarding the health risk...

Renal dialysis services in the Eastern Regional Health Authority: a review of patient satisfaction across hospitals

Kay Rundle, Orla Keegan & Hannah McGee
Recent changes to the health services have initiated a consumer-oriented approach to health care. The current national health strategy in Ireland “Quality and fairness: a health service for you” emphasises the principles of equity and fairness, a peoplecentred service, clear accountability and quality of care (Department of Health and Children, 2001). A consequence of these changes is the consideration of patient views of their health care, and this is often evaluated in the form of...

Public perceptions of biomedical research: a survey of the general population in Ireland

, Hannah McGee, Lena Ring, , Elaine W. Kay, David T. Croke & David Tomkin
In Ireland, in the context of an increasingly knowledge-focused society, financial support for health-related research has increased exponentially in the last decade. Yet little is known about the views of the public, in Ireland and elsewhere, on developments in science, medicine and technology which affect their lives. The aim of the present study was to provide the first nationally representative profile regarding public perceptions on use of human tissue in medical research in Ireland. Specifically,...

The SAVI report: sexual abuse and violence in Ireland

Hannah McGee, Rebecca Garavan, , Joanne Byrne &
The prevalence of sexual violence in Ireland is unknown. Incomplete evidence from crime statistics, previous research reports and service uptake figures is insufficient to understand the nature and extent of the problem and to plan and evaluate services and preventive interventions. The main aim of the SAVI study was to estimate the prevalence of various forms of sexual violence among Irish women and men across the lifespan from childhood through adulthood. Additional aims of the...

One Island – Two Systems: A comparison of health status and health and social service use by community-dwelling older people in the Republic of Ireland and Northern Ireland

Hannah McGee, Ann O'Hanlon, Maja Barker, Anne Hickey, Rebecca Garavan, , Richard Layte, Emer Shelley, Frances Horgan, Vivienne Crawford, Robert Stout & Desmond O'Neill
This project involves a cross-sectional study of community- dwelling older people aged 65 + years in the Republic of Ireland and Northern Ireland. Significant differences exist in policy, structures, coverage and funding between the two healthcare systems. These differences – a ‘one island – two systems’ situation – provide a unique opportunity to learn by comparing the health, social status and service experiences of two groups of older people on one island with two differing...

Scoping Review of Experience of People living with Inherited Cardiac Conditions and Congenital Heart Disease. The experience of individuals with inherited cardiac conditions and congenital heart disease and their families throughout the life course: impact, difficulties and resilience

Annette Burns, Anne Hickey & Frank Doyle
This was a scoping review of the experiences of people with inherited cardiac conditions and congenital heart disease and their families. The Irish Heart Foundation is trying to investigate the issues which these individuals and their families might face throughout the life course. It is hoped that this scoping review will highlight current knowledge, inform potential future studies and also inform the supports provided by the IHF to people with inherited cardiac conditions and their...

Tracking global HIV / AIDS initiatives and their effects on the health system in Zambia.

This policy brief shows the impact of three global health initiatives - the World Bank Multi Country AIDS program (MAP), the Global Fund to fight AIDS, Tuberculosis, and Malaria (GFATM) and the President’s Emergency Plan For AIDS Relief (PEPFAR)- at national and sub-national levels in Zambia, including the effects on scale up of focal (HIV/AIDS) and non-focal health services, human resources for health, coordination and governance.

Global HIV / AIDS Initiatives and Human Resources for Health in Zambia

This policy brief shows how the rapid scale-up of HIV / AIDS services has affected human resources for health in Zambia. It focuses on health worker numbers and trends, workloads, retention and training. It is based on research conducted in three districts in Zambia: Lusaka and Kabwe (urban districts) and Mumbwa (rural district). The overall study explored the effects of three GHIs on the Zambian health system: the Global Fund to fight AIDS, TB and...

Brain Drain to Brain Gain: Ireland's Two-Way Flow of Doctors

Aisling M. Walsh & Ruairi F. Brugha
Medical workforce stressors continue to undermine Ireland’s ability to achieve medical workforce sustainability and compliance with the WHO Global Code on the International Recruitment of health personnel. These include: i) high rates of emigration among graduates of Irish medical schools, attracted by working conditions, training and career opportunities in other English speaking countries; ii) the need to be compliant with the European Working Time Directive, which restricts hospital doctors’ working week; and iii) increasing demand....

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