55,044 Works

Integrating Alternative Fuels in the North Carolina Transportation Sector

Displacing diesel and gasoline with electricity and compressed natural gas is a strategy to increase energy security, reduce greenhouse gas (GHG) emissions, and improve air quality in North Carolina. The energy capacity of renewable electricity (solar, offshore wind, hydropower, and biomass) and renewable natural gas (methane collected from landfills, wastewater treatment plants, and concentrated animal farm operations) in North Carolina is estimated at the county level. Solar dominates at 90 percent of the total renewable...

To Greek or Not To Greek? Impacts of Fraternity and Sorority Involvement on Academic Outcomes

The academic and social impacts of fraternal organizations on college campuses have become a topic of more fervent debate in recent years. Recruitment websites for Greek life often claim that fraternity and sorority members achieve greater levels of campus involvement and academic success. Contrastingly, critics of the Greek system point to reputed negative social impacts, including contributions to rape culture, dangerous hazing of new initiates, and incidences of alcohol poisoning, and common media stereotypes to...

Wave IV College Mobility Data Documentation

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At Wave IV of the Add Health survey, respondents were asked if they had received a bachelor’s degree. Respondents who answered in the affirmative were then asked to report the institution from which they received this degree. Using the institution from which they received their bachelor’s degree, data from the Mobility Report Card: The Role of Colleges in Intergenerational Mobility (Chetty 2017) were linked to the Add Health respondents. For variables C4CMR01-C4CMR11M, data came from...

1981 Planning Legislation in North Carolina and Other Southeastern States

State legislatures convened this spring in North Carolina and four neighboring states — Virginia, Tennessee, South Carolina, and Georgia. This article outlines some of the legislation enacted in these five states that will affect planning practice or be of interest to planners. Author's Note: All of the legislation mentioned in this article was enacted prior to August 1, 1981, during a regular session of the state legislature in one of the five states. The regular...

Unwieldy Rules and Default Practices: Realities of Public Record-Keeping in North Carolina

Under current law records made in the transaction of public business are considered public and subject to inspection. This aspiration of an open and accountable government is not as simple as the broad statutes may seem to imply. Public content is being created at an exponential rate and policies guiding the management of public records are confusing. Current assumptions are incentives for public officials just to keep all records indefinitely. A flawed system of public...

Informed Consent for Elective Abortion: A Policy Analysis for North Carolina

Abortion is a divisive issue. People on both the pro-life and pro-choice sides of the debate hold strong beliefs about the morality of abortion and how available it should be to women with unintended pregnancies. Its controversy not withstanding, it is an extremely common occurrence. More than a million women had an abortion in 2005, and estimates suggest that one in four women in America will have an abortion in her lifetime. Therefore, abortion services...

Admixture Mapping of African–American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes

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Recent genetic admixture coupled with striking differences in incidence of estrogen receptor (ER) breast cancer subtypes, as well as severity, between women of African and European ancestry, provides an excellent rationale for performing admixture mapping in African American women with breast cancer risk. We performed the largest breast cancer admixture mapping study with in African American women to identify novel genomic regions associated with the disease. We conducted a genome-wide admixture scan using 2,624 autosomal...

Intraoperative Electrocochleographic Characteristics of Auditory Neuropathy Spectrum Disorder in Cochlear Implant Subjects

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Auditory neuropathy spectrum disorder (ANSD) is characterized by an apparent discrepancy between measures of cochlear and neural function based on auditory brainstem response (ABR) testing. Clinical indicators of ANSD are a present cochlear microphonic (CM) with small or absent wave V. Many identified ANSD patients have speech impairment severe enough that cochlear implantation (CI) is indicated. To better understand the cochleae identified with ANSD that lead to a CI, we performed intraoperative round window electrocochleography...

Maternal Ube3a is Required for Neurotypical Motivational Drive and GABA co-release

Dopaminergic projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) are known to be critical players in motivated, reward-seeking behaviors and are involved in learning processes during positive-reinforcement. These neurons co-release several neurotransmitters in the NAc, however; their differential role in motivation and positive-reinforcement is unknown. Angelman syndrome (AS) is a neurodevelopmental disorder caused by the deletion or mutation of the E3-ubiquitin ligase, Ube3a. Ube3a is monoallelically expressed from the maternal allele...

Risk Factors for Neurocognitive Functioning in Children with Autosomal Recessive Polycystic Kidney Disease

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This mini review provides an overview of the issues and challenges inherent in autosomal recessive polycystic kidney disease (ARPKD), with a particular focus on the neurological factors and neurocognitive functioning of this population. ARPKD typically is discovered at the end of pregnancy or during the neonatal developmental period and occurs in approximately 1 in 20,000 live births. During the neonatal period, there is a relatively high risk of death, with many infants dying from respiratory...

The early stages of schizophrenia: Speculations on pathogenesis, pathophysiology, and therapeutic approaches

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Schizophrenia is commonly considered a neurodevelopmental disorder that is associated with significant morbidity; however, unlike other neurodevelopmental disorders, the symptoms of schizophrenia often do not manifest for decades. In most patients, the formal onset of schizophrenia is preceded by prodromal symptoms, including positive symptoms, mood symptoms, cognitive symptoms, and social withdrawal. The proximal events that trigger the formal onset of schizophrenia are not clear but may include developmental biological events and environmental interactions or stressors....

Therapeutic ultrasound as a potential male contraceptive: power, frequency and temperature required to deplete rat testes of meiotic cells and epididymides of sperm determined using a commercially available system

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Abstract Background Studies published in the 1970s by Mostafa S. Fahim and colleagues showed that a short treatment with ultrasound caused the depletion of germ cells and infertility. The goal of the current study was to determine if a commercially available therapeutic ultrasound generator and transducer could be used as the basis for a male contraceptive. Methods Sprague-Dawley rats were anesthetized and their testes were treated with 1 MHz or 3 MHz ultrasound while varying...

Quantification of Viral and Prokaryotic Production Rates in Benthic Ecosystems: A Methods Comparison

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Viruses profoundly influence benthic marine ecosystems by infecting and subsequently killing their prokaryotic hosts, thereby impacting the cycling of carbon and nutrients. Previously conducted studies, based on different methodologies, have provided widely differing estimates of the relevance of viruses on benthic prokaryotes. There has been no attempt so far to compare these independent approaches, including contextual comparisons among different approaches for sample manipulation (i.e., dilution or not of the sediments during incubations), between methods based...

Gender Based Family Planning: An Analysis into Underlying Reasons for Male Preference in India

This paper explores the reasons behind gender bias and the skewed sex-ratio in India by looking at gender based family planning. Current literature suggests that regional factors, education, and age of mother are major factors—among others—that highly influence whether or not a family will have gender bias (towards boys). The question is approached by specifying a gender-based family planning based on Gary Becker’s demand for children model, but I have split demand for children into...

Teaching and Assessing Population Health in Undergraduate Medical Education

Background: Despite increased initiatives to teach population health in undergraduate medical education, there remains a lack of consensus on both the appropriate didactic content and methods of assessment necessary to establish a unified foundation for all graduates of medical school. Objective: To better understand the outcomes of interest for these new educational initiatives and to explore methods for assessing medical student outcomes. Methods: In-depth interviews with experts in medical education at national policymaking organizations and...

The filter map: Media and the pursuit of truth and legitimacy

What kinds of media messages should we choose to receive, and how seriously should we take them? These questions are much more urgent now than they were in the pre-digital era, when we had far less control over the information we consumed. Back then, nearly all our media options came from the major TV networks, movie studios, book publishers, radio broadcasters and local news monopolies. Today, anyone can add to our inexhaustible menu of media...

The Coach-Athlete Relationship and Athlete Psychological Outcomes

Athletes’ relationships with their coaches have important implications for outcomes of psychological health. Further examination of these associations is needed to identify the aspects of the coach-athlete relationship most linked to athlete burnout and engagement. This study examined associations among athlete perceptions of the coach-athlete relationship and burnout and engagement across a competitive season. We hypothesized that athlete endorsement of higher levels of markers of the coach-athlete relationship (closeness, commitment, and complementarity) would be negatively...

The Reference Interview: Theories and Practice

The reference librarian's task is to translate the patron's question into one that can be answered with the library's resources. The first element of that task is to know what the patron wants; the second is to know what resources the library has and how to use them. Reference librarians must learn continuously throughout their careers, both because new resources become available, but also because patrons present questions requiring new resources. This article will focus...

The Association Between a History of Adverse Childhood Experiences and Current Parenting Beliefs and Attitudes

Background: Adverse Childhood Experiences are a significant health problem with some negative consequences persisting into subsequent generations. One proposed mechanism for this is the influence of ACEs on parenting behavior. Objective: This study seeks to examine the relationship between a history of ACEs and parenting attitudes and styles. Participants and Setting: This study investigates the baseline data of the Child Adult Relationship Enhancement in Primary Care (PriCARE) trial at the University of North Carolina Children’s...

User-Enacted Determinants of Presence: Sound Effects and Feedback in Multiplayer Console Gameplay

A 1 x 2 multivariate analysis of covariance was conducted to assess the influence of auditory feedback on presence in Super Smash Bros. Brawl. 41 participants were assigned to a gameplay treatment condition of muted audio or sound effects only. Dependent variables were measured by the Self-Assessment Manikin, ITC-Sense of Presence Inventory, and Temple Presence Inventory. Covariates included familiarity with controls, visuospatial working memory, the Immersive Tendencies Questionnaire, recent gameplay experience, computer opponent difficulty level,...

The Development of a Novel Series of Cationic Porphyrins as Disinfectants for Use in Public Health

In the United States, alone, an estimated 4 million to 33 million cases of gastrointestinal illness resulting from contaminated water supplies occur annually. There is a need for the exploration of new types of disinfectants for water treatment with different mechanisms of action that can be used along with or in place of currently used disinfectants to further improve modern drinking water treatment. Photodynamic inactivation (PDI) of pathogens is a unique approach to water treatment....

Familiarity Breeds Collaboration: An Instructional Technologist & Library Liaison Join Forces to Support E-Learning

Partnership forged while supporting faculty engaged in e-learning: •Relationship has developed over time and during changes in: our roles, our parent organizations, the technology landscape

Increasing Childhood Lead Screening in High-Risk Regions of Virginia through Physician Practice Education and Performance Evaluation

Despite years of elimination efforts, lead poisoning remains one of the most devastating and costly environmental health risks for children. Lead poisoning often has been called a silent epidemic because its presence is often not recognized until after damage has occurred. Young children with elevated blood lead levels most often show no symptoms, yet are suffering from the real and harmful effects of lead poisoning. (Summit for 2010, 2005)

Profiling the metabolic signals involved in chemical communication between microbes using imaging mass spectrometry

The ability of microbes to secrete bioactive chemical signals into their environment has been known for over a century. However, it is only in the last decade that imaging mass spectrometry has provided us with the ability to directly visualize the spatial distributions of these microbial metabolites. This technology involves collecting mass spectra from multiple discrete locations across a biological sample, yielding chemical ‘maps’ that simultaneously reveal the distributions of hundreds of metabolites in two...

An Analysis of the Holdings of Fore-edge Paintings at the University of North Carolina and Duke University's Rare Book Collections

This paper is an analysis of nine selected works decorated with fore-edge paintings, seven of which are located in the Rare Book Collection (RBC) at the University of North Carolina at Chapel Hill, and the other two belonging to Duke University's Rare Book, Manuscript, and Special Collections Library (RBMSCL). The paper includes a brief history of the technique and the context of the selected items within that history. A descriptive bibliography of the works and...

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