164 Works

Spike time dependent plasticity (STDP) data from neonate neuroligin-3 knock-out mice, positive pairing

C. Marchetti, M. Sgritta & E. Cherubini
Spike-time dependent plasticity (STDP is a particular form of Hebbian type of learning which consists in bidirectional modifications of synaptic strength according to the temporal order of pre- and postsynaptic spiking (*Dan Y1, Poo MM (2006) Spike timing-dependent plasticity: from synapse to perception. Physiol Rev 86:1033-1048*). Thus, positively correlated pre- and postsynaptic spiking (pre before post) within a critical window leads to long term potentiation (LTP), whereas a negative correlation (post before pre) leads to...

Individual Brain Charting: ARCHI social

A. Pinho, A. Amadon, T. Ruest, M. Fabre, E. Dohmatob, I. Denghien, C. Ginisty, S. Becuwe-Desmidt, S. Roger, L. Laurier, V. Joly-Testault, G. Médiouni-Cloarec, C. Doublé, B. Martins, P. Pinel, E. Eger, G. Varoquaux, C. Pallier, S. Dehaene, L. Hertz-Pannier & B. Thirion
This dataset contains functional magnetic resonance images (fMRIs) of 12 subjects that examins cognitive functions implicated in social cognition, namely mental abilities linked to the theory-of-mind or social interplay. The paradigm was designed in blocks. The blocks were in turn constituted by a set of trials, each of them containing one event. There were eight types of events, that can be described as follows: (1) watch short movies of triangles, exhibiting a putative social interaction;...

Density measurements of different receptors for Area PGa (IPL) [human, v1.0]

K. Zilles, N. Palomero-Gallagher, K. Amunts & S. Caspers
This dataset contains the densities (in fmol/mg protein) of receptors for classical neurotransmitters in Area PGa (IPL) obtained by means of quantitative _in vitro_ autoradiography. The receptor densities are visualized as _fingerprints_ (**fp**), which provide the mean density and standard deviation for each of the analyzed receptor types, averaged across samples. Overview of available measurements [ **receptor** \| **_neurotransmitter_** \| _labeling agent_ ]: **AMPA** \| **_glutamate_** \| _[3H]AMPA_ **kainate** \| **_glutamate_** \| _[3H]kainate_ **NMDA** \|...

Recordings of cerebellar neuronal firing induced by currents steps

F. Prestori, T. Soda, F. Locatelli, M. Tognolina & E. D'Angelo
Study and characterization of the intrinsic excitability properties of different cerebellar neuronal types.

3D high resolution SRXTM image data of cortical vasculature of rat brain.

B. Weber & M. Schneider
The goal of the study is to produce the first high resolution, 3D reconstruction of the entire macrostructure and vascular system of the rat/mouse brain. To that end synchrotron radiation-based X-ray microscopy images were collected. Then the data is translated into 3D mesh and volumetric models (graph). This dataset contains high resolution tiff image array of part of cortical vasculature of the rat brain. This dataset is used as an input to computational methods that...

Large scale multi-channel EEG in rats

A. Arena & J. Storm
The aim of this task is to develop a protocol and a set-up for recording EEG signal from a large number of cortical areas in head-restrained rats exposed to anesthesia and during wakefulness. In order to quantify cortical complexity and its relation to (un)consciousness, a large scale EEG that samples activity from most of cortical areas is needed (Massimini et al. Science, 2005; Casali et al. Sci Transl Med, 2013). Unfortunately, only few existing probes...

Maps of neurons stained with anti-NeuN antibody

F. Pavone & I. Costantini
This dataset is about 3D-imaging at high resolution of NeuN expressing neurons of selected regions (area 17 of visual cortex) of human brain. The dataset contains the final fused volume in tiff and MP4 format, the originally acquired 3D stacks, as well as the stitching file generated by ZetaStitcher.

Purkinje cell protein 2 tetracycline-transactivator expression: horizontal sections (case 3292)

S. Lillehaug, M. Yetman, M. Puchades, M. Checinska, J. Jankowsky, J.G. Bjaalie & T.B. Leergaard
Bright-field microscopy images of serial horizontal brain sections showing Purkinje cell protein 2 (Pcp2) promoter expression in a bigenic Pcp2-tetracycline-transactivator (tTA) mouse brain (case 3292, adult female), generated using a driver-reporter construct in which the PCP2-tTA promoter regulates the expression of the E. coli derived LacZ reporter gene encoding β-galactosidase, which is visualized histologically using X-gal (5-Bromo-4-chloro-3-indolyl β-d-galactopyranoside) as a substrate. Our data confirm earlier reports that Pcp2-tTA promoter expression is restricted to cerebellar Purkinje...

Pituitary homeobox 3 tetracycline-transactivator expression: coronal sections (case 6517)

S. Lillehaug, M. Yetman, M. Puchades, M. Checinska, J. Jankowsky, J.G. Bjaalie & T.B. Leergaard
Bright-field microscopy images of serial coronal brain sections showing Pituitary homeobox 3 (Pitx3) promoter expression in a bigenic Pitx3-tetracycline-transactivator (tTA) mouse brain (case 6517, adult female), using a driver-reporter construct in which the Pitx3-tTA promoter regulates the expression of the E. coli derived LacZ reporter gene encoding β-galactosidase, which is visualized histologically using X-gal (5-Bromo-4-chloro-3-indolyl β-d-galactopyranoside) as a substrate. Our data show that the Pitx3-tTA promoter is spatially restricted to the substantia nigra, ventral tegmental...

Prion promoter tetracycline-transactivator expression: coronal sections (case 388.12)

J. Boy, T.B. Leergaard, T. Schmidt, F. Odeh, U. Bichelmeier, S. Nuber, C. Holzmann, A. Wree, S. Prusiner, H. Bujard, O. Riess & J.G. Bjaalie
Bright-field microscopy images of serial coronal brain sections showing prion promoter (Prnp) promoter expression in a bigenic Prnp-tetracycline-transactivator (tTA) mouse brain (case 388.12, adult female), using a driver-reporter construct in which the Prnp-tTA promoter regulates the expression of the E. coli derived LacZ reporter gene encoding β-galactosidase, which is visualized histologically using X-gal (5-Bromo-4-chloro-3-indolyl β-d-galactopyranoside) as a substrate. Methodological details are provided in Boy et al., Neuroimage 33:449-62, 2006. Our data show that the Prnp-tTA...

Probabilistic cytoarchitectonic map of Area PFop (IPL) (v9.2)

S. Caspers, S. Geyer, S. B. Eickhoff, A. Schleicher, H. Mohlberg, F. Scheperjans, K. Zilles & K. Amunts
This dataset contains the distinct probabilistic cytoarchitectonic map of Area PFop (IPL) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the...

Probabilistic cytoarchitectonic map of Area hOc4lp (LOC) (v3.2)

A. Malikovic, K. Amunts, A. Schleicher, H. Mohlberg, M. Kujovic, N. Palomero-Gallagher, S. B. Eickhoff & K. Zilles
This dataset contains the distinct probabilistic cytoarchitectonic map of Area hOc4lp (LOC) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the...

Probabilistic cytoarchitectonic map of Ch 123 (Basal Forebrain) (v4.0)

L. Zaborszky, L. Hoemke, H. Mohlberg, A. Schleicher, K. Amunts & K. Zilles
This dataset contains the distinct probabilistic cytoarchitectonic map of Ch 123 (Basal Forebrain) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to...

Spontaneous inhibitory post-synaptic currents recorded from CA1 pyramidal neurons of adult wild type Tg2576 mice

C. Marchetti, E. Cherubini & S. Marinelli
A general procedure to fit individual synaptic events recorded from voltage clamp experiments was tested with various sets of experimental data on GABAergic synapses; gephyrin and gephyrin-dependent pathways were chosen as a suitable example of a kinetic model of synaptic transmission. The data used here are obtained from coronal hippocampal slices (300 μm thick) from 3 to 4 months old Tg2576 (carrying the Amyloid Precursor Protein KM670/671NL Swedish mutation) female mice. The dataset contains 1000...

Probabilistic cytoarchitectonic map of Area Fp1 (FPole) (v2.2)

S. Bludau, S. B. Eickhoff, H. Mohlberg, S. Caspers, A. Laird, P. Fox, A. Schleicher, K. Zilles & K. Amunts
This dataset contains the distinct probabilistic cytoarchitectonic map of Area Fp1 (FPole) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the reference space, where each voxel...

Brain-wide distribution of glutamate type 1 transporter protein (GLT1)

S. Holmseth, H. Scott, K. Real, K. Lehre, T.B. Leergaard, J.G. Bjaalie & N. Danbolt
Glutamate is the major excitatory transmitter in the central nervous system (Danbolt, Prog. Neurobiol. 65:1-105, 2001). It is inactivated by cellular uptake, mostly catalyzed by the glutamate transporters GLT1 (slc1a2, excitatory amino acid transporter [EAAT2]) subtype expressed at high levels in brain astrocytes and at lower levels in neurons. Three C-terminal variants of EAAT2 exist: GLT1a (Pines et al., Nature 360:464-467, 1992), GLT1b (Utsunomiya-Tate et al., FEBS Lett 416:312-326,1997), and GLT1c (Rauen et al., Neurochem....

Probabilistic cytoarchitectonic map of Area OP4 (POperc) (v9.2)

S. B. Eickhoff, A. Schleicher, K. Amunts, H. Mohlberg & K. Zilles
This dataset contains the distinct probabilistic cytoarchitectonic map of Area OP4 (POperc) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the...

Probabilistic cytoarchitectonic map of Area TE 1.0 (HESCHL) (v5.0)

P. Morosan, J. Rademacher, A. Schleicher, K. Amunts, T. Schormann, C. Werner, H. Freund & K. Zilles
This dataset contains the distinct probabilistic cytoarchitectonic map of Area TE 1.0 (HESCHL) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to...

Probabilistic cytoarchitectonic map of Area hOc4d (Cuneus) (v2.2)

M. Kujovic, K. Zilles, A. Malikovic, A. Schleicher, H. Mohlberg, C. Rottschy, S. B. Eickhoff & K. Amunts
This dataset contains the distinct probabilistic cytoarchitectonic map of Area hOc4d (Cuneus) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the...

Probabilistic cytoarchitectonic map of Area hOc1 (V1, 17, CalcS) (v2.2)

K. Amunts, A. Malikovic, H. Mohlberg, T. Schormann & K. Zilles
This dataset contains the distinct probabilistic cytoarchitectonic map of Area hOc1 (V1, 17, CalcS) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the reference space, where...

Probabilistic cytoarchitectonic map of HATA (Hippocampus) (v11b.0)

K. Amunts, O. Kedo, M. Kindler, P. Pieperhoff, H. Mohlberg, N. J. Shah, U. Habel, F. Schneider & K. Zilles
This dataset contains the distinct probabilistic cytoarchitectonic map of HATA (Hippocampus) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the reference...

Probabilistic cytoarchitectonic map of Area hIP1 (IPS) (v6.0)

H. Choi, K. Zilles, H. Mohlberg, A. Schleicher, G. Fink, E. Armstrong & K. Amunts
This dataset contains the distinct probabilistic cytoarchitectonic map of Area hIP1 (IPS) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the reference space, where each voxel...

Probabilistic cytoarchitectonic map of Area 3b (PostCG) (v8.2)

S. Geyer, A. Schleicher, T. Schormann, H. Mohlberg & K. Zilles
This dataset contains the distinct probabilistic cytoarchitectonic map of Area 3b (PostCG) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the...

Probabilistic cytoarchitectonic map of Area hIP3 (IPS) (v8.2)

F. Scheperjans, K. Hermann, S. B. Eickhoff, K. Amunts, A. Schleicher, L. Hoemke, H. Mohlberg & K. Zilles
This dataset contains the distinct probabilistic cytoarchitectonic map of Area hIP3 (IPS) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the reference space, where each voxel...

Probabilistic cytoarchitectonic map of Area FG1 (FusG) (v1.2)

J. Caspers, K. Zilles, S. B. Eickhoff, A. Schleicher, H. Mohlberg & K. Amunts
This dataset contains the distinct probabilistic cytoarchitectonic map of Area FG1 (FusG) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the...

Registration Year

  • 2018
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  • Dataset
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