2 Works

3D Bioprinting and Implantation of Mouse Mammary Epithelial Structures Using a Custom Accessible 3D Bioprinting Platform

Xavier-Lewis Palmer, Saad Jafri, Patrick C. Sachs & Robert D. Bruno
Prior work has shown that our bioprinting system can reliably produce human mammary organoids and tumoroids with high precision. However, this was not previously applied to mouse models, which are also important with respect to translational research in cancer drug development. To address this, we have produced protocols for the development of in vitro structures from murine mammary epithelial and tumor cells. Additionally, we assessed the translatability of both human and murine bioprinted organoids into...

Multi-Modality Breast MRI Segmentation Using nn-UNet for Preoperative Planning of Robotic Surgery Navigation

Motaz Alqaoud, John Plemmons, Eric Feliberti, Kaipa, Siqin Dong, Gabor Fichtinger, Yimming Xiao & Michel Audette
Segmentation of the chest region and breast tissues is essential for surgery planning and navigation. This paper proposes the foundation for preoperative segmentation based on two cascaded architectures of deep neural networks (DNN) based on the state-of-the-art nnU-Net. Additionally, this study introduces a polyvinyl alcohol cryogel (PVA-C) breast phantom based on the segmentation of the DNN automated approach, enabling the experiments of navigation system for robotic breast surgery. Multi-modality breast MRI datasets of T2W and...

Registration Year

  • 2022

Resource Types

  • Text


  • Old Dominion University
  • Eastern Virginia Medical School
  • Queen's University
  • Concordia University