7,560 Works

Toxoplasmosis in Germany: Epidemiology, Diagnosis, Risk Factors, and Treatment

Uwe Pleyer, Uwe Groß, Dirk Schlüter, Hendrik Wilking & Frank Seeber
Background: With approximately 30% of the world population infected, Toxoplasma gondii is one of the most widespread pathogenic parasites in both humans and animals and a major problem for health economics in many countries. Methods: This review is based on the findings of individual studies, meta-analyses, and Cochrane Reviews retrieved by a selective literature survey of the Medline and Google Scholar databases. Results: Current data indicate a high rate of Toxoplasma gondii infection in Germany,...

Aktuelle Mitteilungen über verschiedene Personen

Ludwig Brieger

Persönliche Mitteilungen über verschiedene Personen und Malaria-Publikationen

Richard Pfeiffer

Cholera in Altona 1893: Situation im Ortsteil Langer Jammer

Richard Pfeiffer

Differences in MHC-B diversity and KIR epitopes in two populations of wild chimpanzees

Vincent Maibach, Kevin Langergraber, Fabian H. Leendertz, Roman M. Wittig & Linda Vigilant
The major histocompatibility complex (MHC) class I genes play a critical role within the immune system, both by the presentation of antigens from intracellular pathogens to immunocompetent cells and by the interaction with killer cell immunoglobulin-like receptors (KIR) on natural killer cells (NK cells). Genes of the MHC are highly diverse, and MHC variation can have effects on the immune functionality of individuals; hence, comparisons of MHC diversity among closely related phylogenetic taxa may give...

Patentangelegenheit und Tuberkulose-Forschungen

Ludwig Brieger

Gesetz für den Schutz vor Masern und zur Stärkung der Impfprävention (Masernschutzgesetz)

NK Küpke, D Matysiak-Klose, A Siedler, O Wiechmann & M Diercke
Seit dem 1.3.2020 gilt das Masernschutzgesetz. Im Zentrum des Gesetzes steht eine Nachweispflicht für das Vorliegen einer Masern-Immunität für besondere Personengruppen. Das Masernschutzgesetz sieht flankierende Maßnahmen dabei vor: eine Meldepflicht für SSPE und Nachweise von S. pneumoniae. Ferner ist, wie das Epidemiologische Bulletin 10/2020 ausführt, nun jeder Arzt zur Durchführung der Schutzimpfung berechtigt, Krankenkassen können Versicherte über fällige Schutzimpfungen informieren. Darüber hinaus sind im Masernschutzgesetz weitere neue Meldepflichten nach IfSG geregelt. Diese betreffen die zoonotische...

Erfassung der SARS-CoV-2-Testzahlen in Deutschland

Janna Seifried & Osamah Hamouda
Im Rahmen der COVID-19-Pandemie spielt die Labordiagnostik zu SARS-CoV-2 eine entscheidende Rolle. Die Bedeutung liegt nicht nur in der diagnostischen Abklärung, sondern hat eine herausragende Stellung für die Beurteilung der epidemiologischen Entwicklung und hinsichtlich Strategien zur Verlangsamung des aktuellen Geschehens in Deutschland. Daten zur Anzahl der durchgeführten Testungen zu SARS-CoV-2 sowie zur Anzahl der Personen mit den jeweiligen Testergebnissen und den Testkapazitäten werden aktuell über verschiedene Netzwerke bzw. Umfragen erhoben. Dazu gibt der Artikel einen...

Cohort profile: KiGGS cohort longitudinal study on the health of children, adolescents and young adults in Germany

Elvira Mauz, Michael Lange, Robin Houben, Robert Hoffmann, Jennifer Allen, Antje Gößwald, Heike Hölling, Thomas Lampert, Cornelia Lange, Christina Poethko-Müller, Almut Richter, Angelika Schaffrath Rosario, Ursula Von Schenck, Thomas Ziese, Bärbel-Maria Kurth & The KIGGS Cohort Research Team

Häusliche Isolierung bei bestätigter COVID-19-Erkrankung

Robert Koch-Institut

STI in times of PrEP: high prevalence of chlamydia, gonorrhea, and mycoplasma at different anatomic sites in men who have sex with men in Germany

Klaus Jansen, Gyde Steffen, Anja Potthoff, Ann-Kathrin Schuppe, Daniel Beer, Heiko Jessen, Stefan Scholten, Petra Spornraft-Ragaller, Viviane Bremer, Carsten Tiemann &
Background Men who have sex with men (MSM) are disproportionally affected by sexually transmitted infections (STI). STI are often extragenital and asymptomatic. Both can delay diagnosis and treatment. Approval of HIV pre-exposure prophylaxis (PrEP) might have influenced sexual behaviour and STI-prevalence of HIV- MSM. We estimated STI-prevalence and risk factors amongst HIV- and HIV+ MSM in Germany to plan effective interventions. Methods We conducted a nationwide, cross-sectional study between February and July 2018. Thirteen MSM-friendly...

Bevorstehende Berufung Pfeiffers an die Universität Königsberg

Richard Pfeiffer

Berichterstattung zu Malaria-Forschungen in Holstein

Paul Frosch

Übersendung von Mücken aus Daressalam; Malaria-Forschungen

Max Beck

Kontaktpersonennachverfolgung bei SARS-CoV-2-Infektionen

Response of Microbial Communities and Their Metabolic Functions to Drying–Rewetting Stress in a Temperate Forest Soil

Dong Liu, Katharina M. Keiblinger, Sonja Leitner, Uwe Wegner, Michael Zimmermann, Stephan Fuchs, Christian Lassek, Katharina Riedel & Sophie Zechmeister-Boltenstern
Global climate change is predicted to alter drought–precipitation patterns, which will likely affect soil microbial communities and their functions, ultimately shifting microbially-mediated biogeochemical cycles. The present study aims to investigate the simultaneous variation of microbial community compositions and functions in response to drought and following rewetting events, using a soil metaproteomics approach. For this, an established field experiment located in an Austrian forest with two levels (moderate and severe stress) of precipitation manipulation was evaluated....

Low 2018/19 vaccine effectiveness against influenza A(H3N2) among 15–64-year-olds in Europe: exploration by birth cohort

Esther Kissling, Francisco Pozo, Silke Buda, Ana-Maria Vilcu, Alin Gherasim, Mia Brytting, Lisa Domegan, Verónica Gómez, Adam Meijer, Mihaela Lazar, Vesna Višekruna Vučina, Ralf Dürrwald, Sylvie Van Der Werf, Amparo Larrauri, Theresa Enkirch, Joan O'Donnell, Raquel Guiomar, Mariëtte Hooiveld, Goranka Petrović, Elena Stoian, Pasi Penttinen, Marta Valenciano &
Introduction Influenza A(H3N2) clades 3C.2a and 3C.3a co-circulated in Europe in 2018/19. Immunological imprinting by first childhood influenza infection may induce future birth cohort differences in vaccine effectiveness (VE). Aim The I-MOVE multicentre primary care test-negative study assessed 2018/19 influenza A(H3N2) VE by age and genetic subgroups to explore VE by birth cohort. Methods We measured VE against influenza A(H3N2) and (sub)clades. We stratified VE by usual age groups (0–14, 15–64, ≥ 65-years). To assess...

High prevalence of hepatitis C virus infection and low level of awareness among people who recently started injecting drugs in a cross-sectional study in Germany, 2011–2014: missed opportunities for hepatitis C testing

Julia Enkelmann, Martyna Gassowski, Stine Nielsen, Benjamin Wenz, Stefan Roß, Ulrich Marcus, Viviane Bremer, Ruth Zimmermann &
Background In Germany, risk of hepatitis C virus (HCV) infection is highest among people who inject drugs (PWID). New injectors (NI) are particularly vulnerable for HCV-acquisition, but little is known about health seeking behaviour and opportunities for intervention in this group. We describe characteristics, HCV prevalence, estimated HCV incidence and awareness of HCV-status among NIs and missed opportunities for hepatitis C testing. Methods People who had injected drugs in the last 12 months were recruited...

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