782 Works

COVID-19: Verdachtsabklärung und Maßnahmen

Age, maturation and serum lipid parameters: findings from the German Health Survey for Children and Adolescents

Anja Schienkiewitz, Julia Truthmann, Andrea Ernert, Susanna Wiegand, Karl Otfried Schwab & Christa Scheidt-Nave
Background Recommendations on preventive lipid screening among children and adolescents remain controversial. The aim of the study was to assess age and puberty-related changes in serum lipids, including total cholesterol (TC), and high-density (HDL-C) and non-high-density lipoprotein cholesterol (Non-HDL-C). Methods Using cross-sectional data from the National Health Interview and Examination Survey for Children and Adolescents in Germany (KiGGS 2003–2006; N = 13,676; 1–17 years), changes in distributions of serum lipids were visualized according to sex,...

Genetic, Epigenetic and Phenotypic Diversity of Four Bacillus velezensis Strains Used for Plant Protection or as Probiotics

Oleg N. Reva, Dirk Z. H. Swanevelder, Liberata A. Mwita, Aneth David Mwakilili, Dillon Muzondiwa, Monique Joubert, Wai Yin Chan, Stefanie Lutz, Christian H. Ahrens, Lylia V. Avdeeva, Maksim A. Kharkhota, Donatha Tibuhwa, Sylvester Lyantagaye, Joachim Vater, Rainer Borriss & Johan Meijer
Bacillus velezensis strains are applied as ecologically safe biopesticides, plant growth promoting rhizobacteria (PGPR), and in veterinary probiotics. They are abundant in various environments including soil, plants, marine habitats, the intestinal micro-flora, etc. The mechanisms underlying this adaptive plasticity and bioactivity are not well understood, nor is it clear why several strains outperform other same species isolates by their bioactivities. The main objective of this work was to demonstrate versatility of bioactivities and lifestyle strategies...

Kontaktpersonennachverfolgung bei SARS-CoV-2-Infektionen

Robert Koch-Institut

High prevalence of hepatitis C virus infection and low level of awareness among people who recently started injecting drugs in a cross-sectional study in Germany, 2011–2014: missed opportunities for hepatitis C testing

Julia Enkelmann, Martyna Gassowski, Stine Nielsen, Benjamin Wenz, Stefan Roß, Ulrich Marcus, Viviane Bremer, Ruth Zimmermann &
Background In Germany, risk of hepatitis C virus (HCV) infection is highest among people who inject drugs (PWID). New injectors (NI) are particularly vulnerable for HCV-acquisition, but little is known about health seeking behaviour and opportunities for intervention in this group. We describe characteristics, HCV prevalence, estimated HCV incidence and awareness of HCV-status among NIs and missed opportunities for hepatitis C testing. Methods People who had injected drugs in the last 12 months were recruited...

Toxoplasmosis in Germany: Epidemiology, Diagnosis, Risk Factors, and Treatment

Uwe Pleyer, Uwe Groß, Dirk Schlüter, Hendrik Wilking & Frank Seeber
Background: With approximately 30% of the world population infected, Toxoplasma gondii is one of the most widespread pathogenic parasites in both humans and animals and a major problem for health economics in many countries. Methods: This review is based on the findings of individual studies, meta-analyses, and Cochrane Reviews retrieved by a selective literature survey of the Medline and Google Scholar databases. Results: Current data indicate a high rate of Toxoplasma gondii infection in Germany,...

Response of Microbial Communities and Their Metabolic Functions to Drying–Rewetting Stress in a Temperate Forest Soil

Dong Liu, Katharina M. Keiblinger, Sonja Leitner, Uwe Wegner, Michael Zimmermann, Stephan Fuchs, Christian Lassek, Katharina Riedel & Sophie Zechmeister-Boltenstern
Global climate change is predicted to alter drought–precipitation patterns, which will likely affect soil microbial communities and their functions, ultimately shifting microbially-mediated biogeochemical cycles. The present study aims to investigate the simultaneous variation of microbial community compositions and functions in response to drought and following rewetting events, using a soil metaproteomics approach. For this, an established field experiment located in an Austrian forest with two levels (moderate and severe stress) of precipitation manipulation was evaluated....

Genetic Diversity and Spatial Segregation of Francisella tularensis Subspecies holarctica in Germany

Sandra Appelt, Kristin Köppen, Aleksandar Radonić, Oliver Drechsel, Daniela Jacob, Roland Grunow & Klaus Heuner
Francisella tularensis is an intracellular pleomorphic bacterium and the causative agent of tularemia, a zoonotic disease with a wide host range. Among the F. tularensis subspecies, especially F. tularensis subsp. holarctica is of clinical relevance for European countries. The study presented herein focuses namely on genetic diversity and spatial segregation of F. tularensis subsp. holarctica in Germany, as still limited information is available. The investigation is based on the analysis of 34 F. tularensis subsp....

Cohort profile: KiGGS cohort longitudinal study on the health of children, adolescents and young adults in Germany

Elvira Mauz, Michael Lange, Robin Houben, Robert Hoffmann, Jennifer Allen, Antje Gößwald, Heike Hölling, Thomas Lampert, Cornelia Lange, Christina Poethko-Müller, Almut Richter, Angelika Schaffrath Rosario, Ursula Von Schenck, Thomas Ziese, Bärbel-Maria Kurth & The KIGGS Cohort Research Team

Erfassung der SARS-CoV-2-Testzahlen in Deutschland

Janna Seifried & Osamah Hamouda
Im Rahmen der COVID-19-Pandemie spielt die Labordiagnostik zu SARS-CoV-2 eine entscheidende Rolle. Die Bedeutung liegt nicht nur in der diagnostischen Abklärung, sondern hat eine herausragende Stellung für die Beurteilung der epidemiologischen Entwicklung und hinsichtlich Strategien zur Verlangsamung des aktuellen Geschehens in Deutschland. Daten zur Anzahl der durchgeführten Testungen zu SARS-CoV-2 sowie zur Anzahl der Personen mit den jeweiligen Testergebnissen und den Testkapazitäten werden aktuell über verschiedene Netzwerke bzw. Umfragen erhoben. Dazu gibt der Artikel einen...

Differences in MHC-B diversity and KIR epitopes in two populations of wild chimpanzees

Vincent Maibach, Kevin Langergraber, Fabian H. Leendertz, Roman M. Wittig & Linda Vigilant
The major histocompatibility complex (MHC) class I genes play a critical role within the immune system, both by the presentation of antigens from intracellular pathogens to immunocompetent cells and by the interaction with killer cell immunoglobulin-like receptors (KIR) on natural killer cells (NK cells). Genes of the MHC are highly diverse, and MHC variation can have effects on the immune functionality of individuals; hence, comparisons of MHC diversity among closely related phylogenetic taxa may give...

Cholera in Altona 1893: Situation im Ortsteil Langer Jammer

Richard Pfeiffer

Persönliche Mitteilungen über verschiedene Personen und Malaria-Publikationen

Richard Pfeiffer

Aktuelle Mitteilungen über verschiedene Personen

Ludwig Brieger

Patentangelegenheit und Tuberkulose-Forschungen

Ludwig Brieger

Kontaktpersonennachverfolgung bei SARS-CoV-2-Infektionen

Erfassung der SARS-CoV-2-Testzahlen in Deutschland

Janna Seifried & Osamah Hamouda
Im Rahmen der COVID-19-Pandemie spielt die Labordiagnostik zu SARS-CoV-2 eine entscheidende Rolle. Die Bedeutung liegt nicht nur in der diagnostischen Abklärung, sondern hat eine herausragende Stellung für die Beurteilung der epidemiologischen Entwicklung und hinsichtlich Strategien zur Verlangsamung des aktuellen Geschehens in Deutschland. Daten zur Anzahl der durchgeführten Testungen zu SARS-CoV-2 sowie zur Anzahl der Personen mit den jeweiligen Testergebnissen und den Testkapazitäten werden aktuell über verschiedene Netzwerke bzw. Umfragen erhoben. Dazu gibt der Artikel einen...

PSA ablegen

Robert Koch-Institut

Schutzhandschuhe sicher ausziehen

Robert Koch-Institut

Bevorstehende Berufung Pfeiffers an die Universität Königsberg

Richard Pfeiffer

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  • 2020
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