265,989 Works

\"Still water, who knows you?\" : counter-mapping traditional knowledge and ancestral values with Nak'azdli Whut'en

Jonathan Taggart
Many nations globally are seeking reconciliation with Indigenous peoples who continue to suffer at the hands of colonialism and resource extraction. In Canada, development proponents must engage with First Nations in impact assessment processes, seemingly foregrounding Indigenous values in environmental decision making. Consultation entails traditional use and occupancy (TUO) studies: mapped inventories of subsistence activities and traditional ecological knowledge. However, First Nation communities express dissatisfaction with the way their worlds are represented in assessments: for...

Middle to lower crustal shear zone processes in collisional orogens

Riccardo Graziani
Despite the major role played by shear zones in large-scale deformation accommodation processes across structural levels, the present record of such structures from the lower crust is limited because of sparse exposure of such rocks on Earth. Significant gaps, therefore, remain in our knowledge about the deformation processes and behavior of lower crustal shear zones during collision. This contribution aims to fill that gap by studying the dynamics of the continental lower crust at both...

Feasibility assessment and development of knowledge, technology, and tools for monitoring natural gas odorants

Seyed Mahan Ghazi Mirsaeed
A natural gas (NG) odorization system requires a continuous monitoring system in addition to the proper injection setup. As other sulfur based compounds such as hydrogen sulfide can also coexist in the environment, one of the challenges associated with monitoring the odorants is the selectivity. In this thesis, first, microfluidic gas sensors are modified to enhance their selectivity. In our first study, the effect of microchannel geometry modification (reduction of width) is studied through a...

Adoption of Extended Reality (XR) for enhancement of human capital in the mining workforce of the future

Angarag Otgonbayar
Industry and society are at the beginning stages of the 4th Industrial Revolution or in the case of mining, known as Mining 4.0. Among the multitude of drivers of the new revolution, automation and digitization will transform the nature of human capital within the mining industry. Skill polarization will occur with a reduction in repetitive, low skilled jobs while high skilled programming and engineering jobs will increase. This polarization will benefit those with degrees and...

Development of efficient methods incorporating fluorinated motifs in organic molecules

Paul Foth
Di- and trifluoromethoxyarenes are industrially relevant motifs found in medicinal compounds, agrochemicals, and materials. However, the number of different strategies available to access these di- and trifluoromethoxy arenes are currently limited. Chapter 2 describes the development of a new fluorodecarboxylation method utilizing xenon difluoride for the synthesis of difluoromethoxyarenes. The reaction occurs rapidly and efficiently with facile purification, affording the desired difluoromethoxyarenes in 34–72% yields. Sulfuryl fluoride is an industrially produced insecticidal fumigant that has...

Taking the road less travelled : two essays on encouraging uncommon prosocial behaviors

Rishad Habib
Encouraging prosocial consumer behaviors (i.e., behaviors that involve individual self-sacrifice for the benefit of others) can often be difficult, especially when such behaviors are uncommon. This dissertation illustrates how comparing low rates of descriptive norms (i.e., what people actually do) with other information can highlight the differences between desired and current states, thereby encouraging uncommon, but socially desirable behaviors. I demonstrate how these comparisons can encourage uncommon prosocial behavior in two different domains: charitable giving...

Root canal dentin erosion following different irrigation protocols

Michael Magnusson
Objectives: It has been previously shown that root dentin erosion increases if sodium hypochlorite (NaOCl) is used again following final ethylenediaminetetraacetic acid (EDTA). The purpose of this study is to quantitatively examine the erosion of root dentin when alternating these irrigants during instrumentation. Methods: Eight extracted teeth were instrumented to size #40/04, sequentially from #15/04, using Vortex Blue rotary files (Dentsply Tulsa Dental, Tulsa, OK). Teeth were then randomly divided into four groups based on...

Expelled from the garden? Understanding the dynamics of green gentrification in Vancouver, British Columbia

Daniel Louis Sax
Green gentrification scholarship has indicated that instances of urban greening intended to rectify inequities, can contribute to or elicit shifts in property values, encouraging speculative commercial and retail investment, disrupting existing socio-spatial relationships, and threatening the housing security of residents. Our research contributes to this emergent field of inquiry by 1) synthesizing the academic literature to produce a conceptual framework for green gentrification, and 2) exploring the motivations, justifications, and planning processes leading to the...

Analysis of single telomeres using fluorescence microscopy

Deema Alhusari
Eukaryotic chromosome ends are protected by special DNA structures known as telomeres. In mammals the DNA of telomeres consist of TTAGGG repeats which, in cooperation with specialized proteins, “cap” the ends of chromosomes to protect the chromosomes from end-to-end fusion and erosion. Thus, telomeres are important to maintain chromosome stability and play a vital role in preserving the information in our genome. A key factor of telomeric function is the length of the telomeres. Short...

Investigations on AIS-based vessel trajectory and destination prediction with deep learning

Huei-Kang Wang
Automatic Identification System (AIS) is initially developed for tracking ships to avoid collisions. As numerous small satellites were launched in recent years, millions of AIS messages are captured by these satellite AIS providers every day. The massive amount of data allow shipping firms and port operators to better predict vessels' movement. In this study, a computational framework is developed to predict future trajectories and destinations of vessels by applying deep learning to the satellite AIS...

The rural tax: comprehensive out-of-pocket costs associated with patient travel in British Columbia

, Asif Raza Khowaja, Gal Av-Gay, Eva Sullivan, Anshu Parajulee, Marjorie Dunnebacke, Dorothy Egan, Mickey Balas & Peggy Williamson
Background A significant concern for rural patients is the cost of travel outside of their community for specialist and diagnostic care. Often, these costs are transferred to patients and their families, who also experience stress associated with traveling for care. We sought to examine the rural patient experience by (1) estimating and categorizing the various out of pocket costs associated with traveling for healthcare and (2) describing and measuring patient stress and other experiences associated...

High-definition mapping of the atria using a novel multipolar mapping catheter in patients with complex adult congenital heart disease

Mohammad Paymard & Santabhanu Chakrabarti
Background The Advisor™ HD Grid Mapping Catheter (Abbott Technologies, Minneapolis, MN) has been recently introduced. Although the clinical use of HD Grid mapping catheter is well described in adults with no congenital heart disease, there is limited data on the feasibility of using the HD Grid multipolar catheter to create voltage and activation mapping in adults with congenital heart disease. The purpose of this study was to evaluate the safety and technical feasibility of using...

The neutral-to-the-left mixture model

Sean La
A useful step in data analysis is clustering, in which observations are grouped together in a hopefully meaningful way. The mainstay model for Bayesian nonparametric clustering is the Dirichlet process mixture model, which has one key advantage of inferring the number of clusters automatically. However, the Dirichlet process mixture model has particular characteristics, such as linear growth in the size of clusters and exchangeability, that may not be suitable modelling choices for some data sets,...

Spatial analysis of the opioid overdose epidemic in British Columbia

Ziqiang Hu
Illicit opioid overdose deaths in British Columbia have increased five folds since 2012. Previous studies have identified potential factors that may affect the distribution of fatal and nonfatal overdose risks, such as socioeconomic status, stigma, and access to health care services. Most of these factors affect rural and urban areas differently, and I hypothesize that fatal/nonfatal overdose risks could be higher in rural areas than in urban areas because rural communities are often disadvantaged concerning...

A simulation of epithelial sheet growth with internal signaling

Naba Mukhtar
Epithelial-mesenchymal transition (EMT), a process in which immotile cells that line surfaces in the body become motile mesenchymal cells, plays a crucial role in major processes such as wound healing, embryo development, and cancer growth. Therefore, examining the dynamics behind individual and collective cell migration would allow for a better understanding of these processes. It has been previously observed that the protein YAP is activated by external mechanical stimuli and affects the expression and activation...

Carbon stock and plant communities across an elevation gradient of a semiarid grassland : a 58-year follow up

Alexander James Kramer
Soil and plant communities were examined across an elevation gradient of a grassland steppe ecosystem in the Southern Interior of British Columbia over 58 years (i.e., from 1961 to 2019). In 1961, three distinct zones were classified according to plant species composition and Chernozemic great groups. At the time, grasslands in the area had been in degraded states due to long-term overgrazing, but improved grazing management was put in place in mid-1970s. The objective of...

An Integrated Framework to Conceptualize and Develop the Vancouver Airways Health Literacy Tool (VAHLT)

Iraj Poureslami, Jacek A. Kopec, Noah Tregobov, Rick Sawatzky, Richard Hohn & J. Mark FitzGerald
There is currently no comprehensive tool to assess the functional health literacy (HL) skills of chronic airway disease (CAD) patients. The purpose of this article is to describe the development of a new HL measure, the Vancouver Airways Health Literacy Tool (VAHLT). The tool was developed through the following phases: (1) Tool conceptualization, consisting of: (A) a systematic review (SR), (B) focus group sessions with CAD patients to understand barriers and facilitators to CAD management,...

A retrospective study of the impact of health worker strikes on maternal and child health care utilization in western Kenya

Michael L. Scanlon, Lauren Y. Maldonado, Justus E. Ikemeri, Anjellah Jumah, Getrude Anusu, Jeffrey N. Bone, Sheilah Chelagat, Joann C. Keter, Laura Ruhl, Julia Songok & Astrid Christoffersen-Deb
Background There have been dozens of strikes by health workers in Kenya in the past decade, but there are few studies of their impact on maternal and child health services and outcomes. We conducted a retrospective survey study to assess the impact of nationwide strikes by health workers in 2017 on utilization of maternal and child health services in western Kenya. Methods We utilized a parent study to enroll women who were pregnant in 2017...

Peptidoglycan binding by Pgp2 and Ape1 determines Campylobacter jejuni helical cell shape

Chang Sheng-Huei Lin
The helical morphology of enteropathogenic Campylobacter jejuni is determined by the structure of the peptidoglycan (PG) layer. This structure is dictated by cleavages by the LD-carboxypeptidase Pgp2 and the O-acetyl esterase Ape1 within the periplasm. In this thesis, I used X-ray crystallography, biochemical and genetic methods to investigate the interaction interfaces between these two enzymes and PG to select sites for remodeling to generate a helical cell shape. Pgp2 uses two PG binding sites for...

The northern shore of the N = 40 island of inversion through precision mass measurements and developments towards phase-imaging ion-cyclotron-resonance at the TITAN MPET

William Porter
High-precision nuclear mass measurements are extremely important in furthering our understanding of the nucleus and its properties and interactions. Various different mass spectrometers exist to determine masses of nuclei far from the valley of stability to sufficient precisions, with different strengths applicable to different measurement conditions. TRIUMF's Ion Trap for Atomic and Nuclear science (TITAN) is home to two of these types of spectrometers: the Multiple-Reflection Time-of-Flight Mass Spectrometer (MR-ToF-MS) and Measurement Penning Trap (MPET)....

Characterizing regimes of stratified pilot-ignited direct-injection natural gas combustion in an optically-accessible engine

Jeremy Rochussen
Heavy-duty road transport is a significant contributor of greenhouse gases (GHG) and airborne pollutants, and remains challenging to decarbonize. Application of natural gas (NG) in pilot-ignited direct-injection NG (PIDING) engines has been proven to reduce emissions of pollutants and GHGs relative to conventional diesel engines. Recently, stratified-premixed NG combustion has been identified as a viable approach to further reduce PIDING pollutant emissions. However, there is insufficient experimental data on stratified-premixed PIDING combustion to guide its...

“Honouring the knowledge they possess; it is time we let the patient assess” : bringing the patient voice into workplace-based assessment of pharmacy learners : an interpretive description study

Arwa Nemir
The full abstract for this thesis is available in the body of the thesis, and will be available when the embargo expires.

Understanding African immigrant families’ support for their children’s mathematics learning in Canada

Kwesi Yaro
This research investigates African immigrant families' experiences and perspectives of their children's (10-15-year-old) mathematics learning in the home, community and school settings within the Greater Vancouver area. The study employs the concept of cultural capital framework and Afrocentric worldviews to understand how African immigrant parents support their children’s mathematics learning at the upper elementary and middle grade levels (Grades 4 - 8) in Canada. Specifically, the study addressed the following questions: i) which socio-cultural strategies...

Non-target interactions and humane evaluation of a captive bolt trap on commensal rodents

Erin A'tman Ryan
The Goodnature® A24 automatic rat trap is a self-resetting captive-bolt trap powered by pressurized CO₂, designed with the objective of instantly rendering animals unconscious followed by death, but little research has examined the humaneness of the trap or its potential to harm non-target mammals and birds. This study aimed to identify potential risks to non-target animals, and to evaluate its humaneness in killing target rodents. Seventeen traps, each paired with a motion-activated video camera, were...

Intermedia wearables : the politics of social and spatial transformation in Evelyn Roth’s textile and performance art, 1965-1975

Erika Kindsfather
The full abstract for this thesis is available in the body of the thesis, and will be available when the embargo expires.

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