424 Works

In the Queerest of Ways: A Conversation on Sexuality, Desire, and Futurity

Juana María Rodríguez & Ivy Monroe

Structural basis of bacterial flagellin for NAIP5 binding and NLRC4 inflammasome activation and the mechanism of flagellin induced release of cytokines in vivo

Jian Cui
The bacterial flagellum is a whip-like structure that protrudes from the cell membrane and is one of the most complex and dynamic biological molecular machines that propels bacteria to swim toward beneficial environments and the sites of infection. It is composed of a basal body, a hook, and a long filament. The flagellar filament contains thousands of copies of the protein flagellin (FliC) monomer arranged helically and ending with a filament cap composed of oligomer...

TRANSFORMATIVE LEARNING THROUGH ORAL NARRATIVE IN A PARTICIPATORY COMMUNICATION CONTEXT

Charles Madinger
This research investigates instructional narrative interventions for transformative learning among high orality reliant peoples. Two research questions asked: “Does an oral strategy of radio drama in a participatory environment lead to significant changes in knowledge and beliefs,” with a hypothesis stating there would be significant positive changes; and “When listeners experience narrative transport can it affect receptivity leading to knowledge and belief change,” and the hypothesis stated that narrative transport would correlate to higher positive...

Assessing Machine Learning Utility in Predicting Hydrologic and Nitrate Dynamics in Karst Agroecosystems

Timothy McGill
Seasonal hypoxia in the Gulf of Mexico and harmful algal blooms experienced in many inland freshwater bodies is partially driven due to excessive nitrogen loading seen from agricultural watersheds. Within the Mississippi/Atchafalaya River Basin, many areas are underlain with karst features, and efforts to reduce nitrogen contributions from these areas have had varying success, due to lacking a complete understanding of nutrient dynamics in karst agricultural systems. To improve the understanding of nitrogen cycling in...

An Overview of Functional Communication Training for Registered Behavior Technicians

Christopher Dollinger
Functional Communication Training (FCT) is an intervention involving the differential reinforcement of an alternative response (DRA), in which an appropriate communicative response (e.g., asking for a break) is reinforced while the behavior targeted for decrease (e.g., hitting to get out of work) has reinforcement withheld in its presence. Individuals who work as registered behavior technicians (RBT), under the supervision of a board-certified behavior analyst (BCBA), may implement FCT daily. With that being said, many individuals...

OTAVALAN WOMEN WEAVERS

Kaitlin Zapel
This research focuses on the gendered labor of craft production and distribution of Otavaleños, an indigenous group in the Imbabura Valley in the Andes Mountains of Ecuador. Otavalans are often described as a society of weavers with strong gender divisions. Households typically function as units of production, with tasks ideally broken down along gender lines. Women are generally depicted as secondary workers who do not weave the textiles that make Otavalans famous; however, they are...

Mild Cognitive Impairment in Presurgical Deep Brain Stimulation for Parkinson's Disease

Elizabeth Wallace
Although clinically characterized by motor impairments, Parkinson's disease (PD) often affects cognition early in the disease course. Cognitive changes common in PD include visuospatial abnormalities and prominent executive function (EF) deficits, with 30% of individuals eventually developing Parkinson’s disease dementia (PDD). Mild cognitive impairment (MCI) has been identified as a transitional state between normal cognition and PDD. A large cohort of individuals with PD at the Kentucky Neuroscience Institute have undergone pre-surgical evaluations for deep...

Models and Optimal Controls for Smart Homes and their Integration into the Electric Power Grid

Huangjie Gong
Smart homes can operate as a distributed energy resource (DER), when equipped with controllable high-efficiency appliances, solar photovoltaic (PV) generators, electric vehicles (EV) and energy storage systems (ESS). The high penetration of such buildings changes the typical electric power load profile, which without appropriate controls, may become a “duck curve” when the surplus PV generation is high, or a “dragon curve” when the EV charging load is high. A smart home may contribute to an...

Relations, Ethics, and Storytelling: On Ecology without Culture

Christine Marran, Lee Mandelo & Abby Rudolph

Elephants in the Room

Helen Richardson
The COVID-19 pandemic brought forth unprecedented and ever-changing crisis and disruption to societies and economies around the globe.[1] As the COVID-19 pandemic continues to interrupt travel worldwide, the tourism industry, and the countries who rely on it as a major source of income, are in crisis. These processes have reconfigured economic capital flows and foreign investment in the global south. This is particularly the case in Tanzania, as tourism was Tanzania’s highest foreign exchange earner...

The Use of Video Modeling to Improve Transitions Within a Preschool Classroom

Amanda Duncan
Video modeling is a widely accepted and utilized intervention for students with autism spectrum disorder (ASD). A multiple probe design across participants was utilized to evaluate the effectiveness of using video modeling to decrease transition duration within a preschool classroom. Participants were between the ages of 3-5 and students within an interdisciplinary public preschool classroom in a rural county. All sessions were conducted in the student’s classroom during their typical routine and the intervention was...

THE (MILLENNIAL) TIMES, THEY ARE A’CHANGIN’

Hayley Hoffman
Drawing from over a decade of research, it can be said with relative certainty what millennial learners expected of their instructors when they were in the college classroom. But what about the expectations and needs of our current group of students, Generation Z? Because few studies exist on Gen Z in higher education spaces, this dissertation establishes a baseline of what these students might need and expect from market and generational research on this group...

QUANTITATIVE METHODS FOR TOTAL LIFECYCLE RISK LIKELIHOOD AND IMPACT ASSESSMENT IN SUSTAINABLE PRODUCT DESIGN DECISION MAKING

Christian Enyoghasi
Sustainable products promise significant economic, environmental, and societal benefits. Numerous methods are available for use during the new product development process to identify alternate product designs that optimize sustainability performance. Once any such design is selected and the product is launched, many uncertainties are likely to affect its performance over the total lifecycle. Such uncertainties give rise to risks that can influence the overall product sustainability performance. However, comprehensive quantitative methods to evaluate the likelihood...

Altering the Distance

Brandon Reinkensmeyer
Distancing—a cognitive reappraisal strategy—increases conciliatory policy support (i.e., policies redressing inequity) by reducing anger. Related but distinct research has used construal level theory (CLT), which explains the relationship between psychological distance and mental representations (e.g., events and attitudes), to explore intergroup relations. CLT demonstrates increased psychological distance induces abstract thinking, which leads to high-level construal (HLC) mindsets. HLC mindsets, like distancing, decrease political polarization and prejudice toward out-groups. As both distancing (an appraisal technique) and...

DEVELOPMENT AND PSYCHOMETRIC TESTING OF AN INSTRUMENT TO IDENTIFY FACTORS THAT PREDICT INTENTIONS RELATED TO POST-MORTEM ORGAN DONATION AMONG SAUDI ARABIAN NURSES

Salman Alreshidi
Organ donation shortage is a major international concern. Global data on organ donation and transplantation activities from the World Health Organization indicate that in 2019 organs were available for less than 10% of transplantations needed. In Saudi Arabia alone, the organ donation shortage accounts for 28.8% of deaths annually. Nearly 31% of donated organs are from donors outside of the country because many eligible donors in Saudi Arabia do not donate. While post-mortem organ donation...

NOVEL MECHANISM OF ENDOGENOUS PANCREATIC CANCER CELL EXPRESSION OF IMMUNE CHECKPOINT PROGRAMMED CELL-DEATH 1 PROTEIN (PD-1) INDUCING EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) THROUGH THE MET PATHWAY AND PROMOTING CANCER PROGRESSION IN AN IMMUNE-INDEPENDENT PROCESS

Megan Harper
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers with few treatment options, necessitating an urgent need for novel therapeutics. Immuno-oncologic (IO) therapies have revolutionized anti-cancer regimens in the past decade but typically involve reactivation of adaptive immune responses. In particular, immune checkpoint PD-1 is traditionally expressed only on immune cells while PD-L1 (PD-1 ligand) is overexpressed on cancer cells. When tumor-endogenous PD-L1 binds the PD-1 receptor on T-cells, the immune cells undergo anergy...

THE CORRELATION BETWEEN ACL INJURY & CONCUSSION

Brandon Phillips
Concussion (also known as mild traumatic brain injury) is a neurological injury that occurs after a blow to the head or neck area and can have affects to movement based on the severity of the injury. Mild traumatic brain injury has possible linkage to an increased risk of anterior cruciate ligament (ACL) injury. The purpose of this thesis was to assess the impact of prior concussion on lower extremity mechanics that are associated with risk...

The Utilization of Physical Literacy to Understand Physical Activity in Individuals with a History of Anterior Cruciate Ligament Reconstruction

Rachel Kleis
Injury to the anterior cruciate ligament (ACL) is common in physically active populations. Anterior cruciate ligament reconstruction (ACLR) is commonly performed after injury in order to restore joint stability and knee function and return patients to desired levels of physical activity. However, not everyone will return to their pre-injury levels of sport after surgery and recent evidence reveals that individuals with a history of ACLR are less likely to meet the recommended physical activity guidelines....

Coordinating Boundaries and Negotiating Mental Health Diagnoses and Disclosure

Paige Von Feldt
For quite some time, researchers have tried to reduce stigma and misconceptions about individuals diagnosed with a mental illness. Researchers have examined stigma towards individuals diagnosed with a mental illness, and the internalized stigma that can result. Additionally, researchers have analyzed the dialectical push and pull that occurs between privacy and confidentiality for self-disclosures. Past research has explored disclosure of a mental illness in the context of family members, psychiatrists, employers, friends, and in academic...

METABOLIC DIVERSITY AMONG FIBROBLASTS FROM REGENERATING AND NON-REGENERATING MAMMALS

Ebenezer Aryee
Regeneration is a wound repair process that terminates in the restoration of tissue function and structure. Fibroblasts play pivotal roles in regenerative and fibrotic wound repair. Reports of extensive regenerative ability in mammals have been historically rare, but more recently spiny mice (Acomys) have emerged as a bona fide model of complex tissue regeneration. Recent work has indicated that fibroblasts from regenerators (Acomys and Oryctolagus) are more resistant to reactive oxygen species (ROS)-induced senescence compared...

FROM FEAR TO ACTION

Michele ("Micki") Olson
The extended parallel process model (EPPM) is a popular health and risk communication theory that explicates the relationship between perceived threat, perceived efficacy, fear, and adaptive and maladaptive responses. This study examines the EPPM in an imminent threat context and focuses on how warning message content influences EPPM perceptions and how these perceptions, in turn, influence both protective action and information seeking intentions. The first objective of this study focuses on applying the EPPM to...

The microbiome of the equine roundworm, Parascaris spp.

Jennifer Cain
Parasitic nematodes, including the large roundworms colloquially known as ascarids, affect the health and well-being of livestock animals worldwide. The equine ascarid, Parascaris spp., was the first ascarid parasite to develop wide-spread anthelmintic drug resistance, with other species slowly following suit. There are no new classes of anthelmintics currently in development, and a solution to the ever-increasing prevalence of resistance is desperately needed. The microbiome has been shown to be an important factor in the...

The Development and Validation of the Preservice Music Teacher Self-Efficacy Survey

Christen Dillon
Undergraduate programs to prepare future music teachers at colleges and universities across the United States require skill development in instrumental, choral, and general music (NASM, 2015). These preparation programs require students to matriculate through methods courses (e.g., instrumental methods) to learn pedagogical and content skills necessary to be considered competent music teachers. Although content knowledge and teaching skills could be influencing factors on preservice teachers’ future classroom effectiveness, personal beliefs of individual preservice teachers might...

THE ISOLATED AS THE REVOLUTIONARY

Ruwen Chang
In contemporary China, demographers estimate that 30 million men are single because there are simply not enough women in the Chinese population, and the 2020 Chinese census shows that there are 34.9 million more men than women. These men are called guanggun, which can be directly translated to “bare sticks/branches,” a slur that indicates a lack of marriage and sex. In this project, I demonstrate that guanggun’s singlehood marks them as the marginalized at the...

THE EFFECTIVENESS OF HANDWRITING INTERVENTION ON HANDWRITING AND SPELLING OUTCOMES DELIVERED VIA TELEHEALTH

Laura Bray
Across the United States, there has been a push to improve the literacy of our population, especially in the school systems. This has resulted in emphasizing reading skill development; however, literacy encompasses more than just reading. Literacy is the internal processes needed to create and understand contextualized visual, written, and verbal information. According to the Common Core State Standards, foundational literacy skills include reading, but also writing, listening, and speaking abilities. Handwriting is an area...

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