522 Works

UNDERSTANDING THE EFFECTS OF EMBRYONIC HYPERGLYCEMIA ON RETINAL DEVELOPMENT AND MAINTENANCE

Kayla Titialii-Torres
Hundreds of millions of people are affected by diabetes worldwide. Whether they are diagnosed with prediabetes or Type I or II diabetes, there are a variety of mechanisms in the pathogenesis of diabetes. Diabetes is a disease which consists of recurring states of hyperglycemia that can be difficult to manage due to either lack of insulin production or improper utilization of insulin. While these mechanisms of action differ, complications induced by diabetes occur in both...

Communication Strategies to Intervene in Intimate Partner Violence Among Young Adult Couples

Kaylee Lukacena
Intimate partner violence (IPV) is a social and behavioral health issue of importance among the young adult population (Cupp et al., 2015). IPV includes acts of physical violence, sexual violence, psychological aggression, and stalking enacted by an intimate partner (Smith, Zhang, Basile, Merrick, Wang, Kresnow, & Chen, 2018). In the United States., approximately one in three women and one in ten men experience IPV during their lifetime (Smith et al., 2018). Furthermore, over more than...

Effects of Season and Nutrition on Insulinemic Responses in Insulin Dysregulated Horses

Erica Macon
Insulin dysregulation (ID) is the main risk factor for the development of hyperinsulinemia-associated laminitis (HAL). ID in the equid has been extensively researched; however, recommendations for diagnosing and managing ID horses have originated from work completed in other models, such as the ID pony and healthy horse. Therefore, our overall objective was to improve current diagnostic tools and nutritional management strategies by investigating the effect of season, the fed and fasted state on the oral...

LEVERAGING TRANSCRIPTOMIC APPROACHES TO IDENTIFY DIFFERENCES IN GENETIC PROGRAMMING DRIVING TWO DISTINCT WOUND HEALING MECHANISMS, REGENERATION AND FIBROSIS, IN ACOMYS AND MUS

Shishir Biswas
Why can some animals and others cannot? This fundamental question has fueled scientists studying regeneration for hundreds of years since early observations in crayfish, salamanders and many other organisms. While most contemporary work in regeneration is done in a handful of species including salamanders, zebrafish and flatforms, these organisms lack a closely-related, non-regenerating sister species from which unique genetic differences can be identified. Additionally, while much has been learned from these organisms, they do not...

Therapeutic Targeting of Leukemia Stem Cells to Prevent T-Cell Acute Lymphoblastic Leukemia Relapse

Meghan Green Haney
The survival rate of T-cell Acute Lymphoblastic Leukemia (T-ALL) relapse is a dismal 10% of affected adults and 30% of children, largely due to the relapsed disease being more aggressive and treatment resistant than the initial disease. Relapse is thought to occur because conventional chemotherapies are unable to reliably eliminate a unique cell type known as leukemia stem (or propagating) cells (LSCs). LSCs are the only cells within the leukemia with the ability to self-renew...

CHANGES IN CARDIOVASCULAR, RESPIRATORY, AND NEURAL ACTIVITY BY MUSIC

Mohammad Javad Mollakazemi
Listening to music can induce emotional and physiological changes. Increasing recognition of the palliative effects of music has led to its use as an adjuvant therapeutic tool in the treatment of various diseases. It is also well known that autonomic nervous activities and some cardiorespiratory rhythms change in correspondence with music. However, less is known about how these effects triggered by music come about. Listening to music affects synchronization between electroencephalograms (EEGs) and cardiac rhythmic...

THE PUBLIC SERVICE MOTIVATION OF KENTUCKY 4-H YOUTH DEVELOPMENT AGENTS

Kimberly Adams Leger
The Cooperative Extension Service is known for bringing research and education from the land grant universities to local communities across the state through its County Extension Agents. Kentucky Cooperative Extension 4-H Youth Development Agents have a rich history of educating youth in life skill development. 4-H Agents who traditionally served in these roles often continued their public service until retirement. In recent years, the Kentucky Cooperative Extension Service has documented a decline in 4-H Youth...

Three Essays on Tax Compliance in Indonesia

Himawan Saputro
This dissertation studies the impacts of major tax reforms designed to improve tax compliance, particularly in the context of developing countries with limited enforcement capacity due to informality and lack of third-party data using the Indonesian tax administrative data as well as relevant empirical research methods. In order to describe this dissertation, I discuss each essay as the following. The first essay is titled "How Do Small Taxpayers Respond to Tax Simplification? Evidence from the...

THE LIVES OF OTHERS

Nina Marijanovic
This study examined the topic of faculty satisfaction among faculty employed at the University of Sarajevo (UNSA) in Bosnia and Hercegovina (BiH). BiH has endured a difficult transition from a socialist regime to a market economy following the disintegration of Yugoslavia in the early 1990’s and its higher education sector has been particularly affected by this transition. Scholarly research has focused mostly on the impact of discrimination of certain groups at the primary and secondary...

RELIANCE ON ALGORITHMIC EVIDENCE

Jenny Ulla
Artificial intelligence (AI) systems’ capability is rapidly expanding to perform complex tasks once reserved only for humans. With machine learning algorithms, AI can learn and adapt as it encounters more data, which has enabled these systems to improve the quality of accounting estimates that traditionally have been more difficult for humans. Although AI systems’ capability to adapt has potential benefits, these systems also have become increasingly complex, making it difficult for individuals to understand the...

UNBOXING THE JAPANESE SOJOURNING MOM’S PEDIATRIC-GOING EXPERIENCE

Carolyn Oldham
This study explores how twelve former Lexington-area Japanese sojourning mothers define culturally and linguistically appropriate services and how culture, gender and language shaped their health care beliefs, behaviors and experiences in pediatric settings. It is a naturalistic, pragmatic line of inquiry born in collaboration with Japanese sojourning moms across cups of matcha 末茶 and mugicha 麦茶. Framed by constructivist and intersectionality research lenses, this phenomenological study seeks to understand how study participants perceived the cultural...

A Multiple Goals Perspective on Burnout Disclosure and Support among Attending Physicians

Alison Buckley
Burnout is a common experience among physicians and has been identified as a precursor to substance abuse and suicide ideation. When not addressed, burnout can have many negative personal, relational and professional consequences. Research about the burnout experience is limited due to the taboo nature of the topic. The present study used a multiple goals theoretical perspective to examine how physicians disclose burnout in order to access social support. Attending physicians from various specialties (N...

OXIDATION PRETREATMENT FOR ENHANCED LEACHABILITY OF RARE EARTH ELEMENTS FROM BITUMINOUS COAL SOURCES

Tushar Gupta
Rare earth elements (REEs) are critical components in advanced electronics, clean energy technologies, and national energy and economic security. The global supply situation of these strategically valuable elements remains critical as the market is largely monopolistic. Thus, to alleviate the dependence on global imports, investments are being made in the research and development of innovative and cost-effective technologies for the indigenous processing and recovery of REEs from alternate sources that are cheap and abundant. Numerous...

PREDICTION OF NOISE EMISSIONS USING PANEL CONTRIBUTION ANALYSIS SUPPLEMENTED WITH SCALE MODELING

Gong Cheng
Panel contribution analysis (PCA) can be used to predict machinery noise emissions, component contributions, and to assess the impact of sound reduction treatments. PCA is a measurement approach that is advantageous for complex machinery that is not easily modeled using conventional numerical analysis approaches. In this research, PCA is combined with scale modeling in order to speed up the necessary measurement work. Moreover, the method can be applied to much larger machinery and noise emissions...

Exploring Health and Risk Information Seeking in the Context of COVID-19

Xianlin Jin
Facing a pandemic caused by a novel coronavirus (COVID-19), the public feels uncertainty and fear. To cope with the pandemic and reduce uncertainty, the public needs accurate and prompt information. By theoretically and empirically comparing the Comprehensive Model of Information Seeking (CMIS) and the Risk Information Seeking and Processing Model (RISP), this dissertation aims to unpack the core mechanism of health and risk information seeking. Built on the two models, the author proposed an Integrated...

CIRCUITION

Richard Alan Robinson
Circuition: Concerto for Jazz Guitar and Orchestra is a programmatic musical composition which tells the story of the life cycle. Each part is designed to represent a particular time in life through age or set of events that relate to all people regardless of the specifics in one’s life. Although I disclose how the program of relates to specifics within my own life, the goal is that a listener will find resonance with their own....

TEACHER PERSPECTIVES ON THE INFLUENCE OF PARTICIPATION IN DALCROZE TRAINING IN THE K–12 MUSIC CLASSROOM

Holly Smith
The purpose of this mixed methods study was to examine the teacher perspectives on the influence of participation in Dalcroze training in the K–12 music classroom. A primary goal was to investigate how Dalcroze training influenced music teachers’ classroom instructional practices. An explanatory sequential mixed methods design was use for this study. Participants (N = 91) completed a cross-sectional survey, the Dalcroze Training Experience Questionnaire (DTEQ). Interview participants (N = 6) were selected using stratified...

“ESCAPED FROM DIXIE\"

Stefanie Greenhill
My dissertation, “‘Escaped from Dixie:’ Civil War Refugees and the Creation of a Confederate Diaspora,” examines the experiences of the half a million people who fled from the Confederacy to Union territory under duress during the U.S. Civil War—a massive, diverse movement that had a lasting impact on the nation’s reconstruction in the aftermath of the war. My research considers what prompted refugees to leave, as well as what logistics those escaping from the Confederacy...

Spinoza's Methodology

Clay Graham
Spinoza’s magnum opus, the Ethics, is written in a very peculiar, “geometrical” style, one that builds metaphysical and ethical doctrines out of mathematical, deductive proofs. These proofs rely on a series of definitions, axioms, propositions, and demonstrations. Nowhere in the Ethics does Spinoza explain his fundamental definitions and axioms, nor does he proffer a defense of his manner of presentation. I claim that by a thorough and systematic investigation of his earliest writings we can...

THE SOCIAL BEHAVIOR OF PINE SAWFLIES IN THE GENUS NEODIPRION

John Terbot II
Group living is found across the animal kingdom ranging from temporary mating aggregations to complex, eusocial lifestyles. A particularly common form of group living found among insects are larval or nymphal herds. This lifestyle consists of immature insects living together and results in several proposed costs and benefits. Benefits of this lifestyle include improved ability to regulate a group’s microenvironment, more efficient use of their host, and the ability to engage in collective predator defenses....

STATELESSNESS AND CONTESTED SOVEREIGNTY IN THE MIDDLE EAST

John Perry
This dissertation examines the significance of America’s interactions with stateless actors. It argues that it was groups such as the Muslim Brotherhood, Palestine’s refugees, and ethnic minorities, not the U.S. and Soviet governments, nor the state governments of the region, which dictated how the Cold War unfolded in the Middle East. These groups transformed the policy decisions, strategies, and alliances of both native regimes and the superpowers. Traditionally, historians have looked at the global politics...

WHEN WORLDS COLLIDE

Cheryl Kwok
The relationship experiences of bisexual-identifying men of color have been neglected in psychological studies of race, gender, and sexuality. Few studies, if any, have examined the relationship experiences of Asian bisexual men, even though this population’s multiple marginalized and stigmatized social identities increase their health risks (Bryant-Davis, 2007; Carter, 2007; Ching et al., 2018). Bisexuality is commonly defined by an individual’s intimate partner attraction and/or behavior (e.g., Swan & Habibi, 2018), making relationship experiences fundamental...

Combinatorial Invariants of Rational Polytopes

Andrés Vindas Meléndez
The first part of this dissertation deals with the equivariant Ehrhart theory of the permutahedron. As a starting point to determining the equivariant Ehrhart theory of the permutahedron, Ardila, Schindler, and I obtain a volume formula for the rational polytopes that are fixed by acting on the permutahedron by a permutation, which generalizes a result of Stanley’s for the volume for the standard permutahedron. Building from the aforementioned work, Ardila, Supina, and I determine the...

INTERNATIONAL SCHOOL HEADS’ SELF-EFFICACY AND GOVERNANCE

Joshua Ashley Garrett
As international school heads (ISHs) advance through the school leadership pipeline, many find the transition to their new roles and responsibilities as an executive leader difficult, and as a result they struggle to fulfill the expectations of their governing board. In conversations with ISHs in the International Schools Organization (ISO), a pseudonym, several attributed this problem to the lack of preservice, executive leadership training. Most ISO school heads were trained as teacher-leaders and school principals....

An Explorative Study of Kentucky Teacher Leader Graduate Programs

Bailey Ubellacker
Teacher leadership is a growing practice for supporting K-12 teachers and students. Recent policy regulations in the Commonwealth of Kentucky mandated a change in the professional standards used by approved graduate programs that prepare teacher leaders. To support this foundational change, program leaders designed programmatic goals, curriculum, structure, and tasks to align with the Teacher Leader Model Standards that emphasize promising research-based practices. The programs support development of teacher leadership through pedagogical approach, requirements, and...

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