5 Works

An Evaluation of the Susceptibility of Goats to Larkspur Toxicosis

Kevin D. Welch, Clint A. Stonecipher, Dale R. Gardner, Benidict T. Green & Daniel Cook
Larkspurs (Delphinium spp.) are a major cause of cattle losses in western North America, whereas sheep have been shown to be resistant to larkspur toxicosis. Goats are often used as a small ruminant model to study poisonous plants, even though they can be more resistant to some poisonous plants. It is not known how susceptible goats are to the adverse effects of larkspurs. In this study, we evaluated the susceptibility of goats to larkspur toxicosis...

Dynamics of larkspur (Delphinium barbeyi) pellet consumption and tolerance of the inhibitory effects of larkspur alkaloids on muscle function in cattle.

Benedict T. Green, Jim Pfister, Dale Gardner, Kevin Welch & Daniel Cook
Larkspurs (Delphinium spp.) are toxic native plants on foothill and mountain rangelands in western North America, which poison cattle grazing on those rangelands. The purpose of this study was to examine in a laboratory setting, the subclinical effects of larkspur intake and toxicosis, by allowing larkspur susceptible and resistant cattle to self-select the amount of larkspur consumed in pellet form. We hypothesized that there would be differences in short term (9 – 11 day) pellet...

North American Hard Yellow Liver Disease: An Old Problem Readdressed

Bryan L. Stegelmeier, Meredyth Jones, Christopher P. Womack, T. Zane Davis & Dale R. Gardner
Hard yellow liver disease or fatty cirrhosis periodically affects cattle, sheep, goats, pronghorn antelope (Antilocapra americana) and whitetail deer (Odocoileus virginianus texanus) within several Texas counties in the United States. Clinically it presents as chronic liver disease with progressive hepatic necrosis and fibrosis, icterus and liver failure. The damaged livers are yellow and many have multiple firm, often gritty foci that are scattered throughout all lobes. Early investigations included feeding studies using potential toxic plants,...

Soil and Vegetation Survey of Antelope Pasture, Curlew Grazing Allotment, Oneida County, ID

Merran Owen, Kari E. Veblen, Thomas A. Monaco & Janis L. Boettinger

Rapid Quantitative Analysis of Toxic Norditerpenoid Alkaloids in Larkspur (Delphinium spp.) by Flow Injection - Electrospray Ionization – Mass Spectrometry

Dale R. Gardner, Stephen T. Lee & Daniel Cook
A rapid flow injection - electrospray ionization – mass spectrometry (FI-ESI-MS) method for the quantitative and qualitative analysis of norditerpenoid alkaloids in larkspur plants was developed. The FI-ESI-MS method was calibrated for alkaloid concentrations with larkspur plant samples against an existing Fourier transform infrared spectroscopy FTIR method. There was a strong correlation (r = 0.9926, r = 0.9891) between the FTIR and FI-ESI-MS methods. The relative standard deviation (RSD) for all measurements were ≤ 6.2...

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