2 Works

Data for: Silica Induction of Diverse Inflammatory Proteome in Lungs of Lupus-prone Mice Quelled by Dietary Docosahexaenoic Acid Supplementation

James Pestka, Lichchavi Rajasinghe & Abby Benninghoff
Repeated short-term intranasal instillation of lupus-prone mice with to crystalline silica (cSiO2) induces inflammatory gene expression and ectopic lymphoid neogenesis in the lung, leading to early onset of systemic autoimmunity and rapid progression to glomerulonephritis. These responses are suppressed by dietary supplementation with the ω-3 polyunsaturated fatty acid docosahexaenoic acid (DHA). Here, we tested the hypothesis that dietary DHA supplementation suppresses cSiO2-induced inflammatory proteins in bronchoalveolar alveolar lavage fluid (BALF) and plasma of lupus-prone mice....

Data from: Mapping of Dynamic Transcriptome Changes Associated with Silica-Triggered Autoimmune Pathogenesis in the Lupus-Prone NZBWF1 Mouse.

James Pesta & Abby Benninghoff
The dataset contains six files of tabular data with an accompanying README file. Supplementary file 1: Customized probe annotation file for the Nanostring nCounter Mouse PanCancer Immune Profiling Panel (catalog # 115000142). This file is provided as supporting material for a journal article. Codes for columns are in file. Supplementary file 2: Microsoft Excel document with output from nSolver for differential expression analyses for pairwise comparisons noted by each named sheet. This data set is...

Registration Year

  • 2021
  • 2019

Resource Types

  • Dataset


  • Utah State University
  • Michigan State University