Molecular mechanisms underlying synaptic material clearance by microglia after CNS injury

Geoffrey Norris
Phagocytosis of synaptic material by microglia is critical for CNS development. Less well understood is this microglial function in the injured adult brain. Assay of microglial phagocytosis is challenging, because peripheral myeloid cells engraft the site of injury, which could obscure interpretation of microglial roles. This thesis shows how neurodegenerative debris is cleared by microglia and offers a model for studying its mechanisms and physiological roles. I have focused on the role of neuronal activity...

Ways to Consider Driverless Vehicles in Virginia Long Range Travel Demand Models

Di Kang
Regional travel demand models are an institutionalized element of the transportation planning process, requiring a multiyear investment from collaborating agencies that rely on model outputs to assist with project prioritization and community visioning. The purpose of this research is to identify ways in which Virginia might (1) alter existing travel demand models in order to consider the impacts of driverless vehicles and (2) use such models to inform questions of interest to regional planners. Because...

The \"Communist Question\" Cases Reconsidered

Daniel Auten
This paper focuses on the American Bar Association's (ABA) and state bar associations’ responses to communism in the 1950’s and beyond. In particular, it re-examines the actions the bar took against communist ideology in the era of “McCarthyism.” The dominant historical narrative is that the ABA and state bar associations were merely swept up in the national hysteria of McCarthyism, and this explains the actions the bar took against communists in this period. However, the...

Seagrass as a Coastal Filter: Investigating the Role of Seagrass Meadows in Mediating Nitrogen Cycling in Shallow Coastal Lagoons

Lillian Aoki
Seagrass meadows are highly productive ecosystems that are widely distributed in coastal waters throughout the world. In shallow coastal lagoons, seagrass meadows provide an important ecosystem function by acting as a nitrogen filter. Nitrogen (N) that enters the lagoon is temporarily retained in seagrass biomass and is removed from the system through burial and denitrification in sediments. This filter function contributes to the health of seagrass ecosystems by reducing nitrogen in the water column, slowing...

Simulated Data Sets for the Megamaser Cosmology Project

Jiwon Han
The Megamaser Cosmology Project (MCP) is an NRAO Key Science Project to measure the Hubble Constant, $H_0$, by determining geometric distances to circumnuclear 22 GHz $\text{H}_2\text{O}$ megamasers in galaxies well into the Hubble flow. Two independent measurements from VLBI mapping and single-dish spectral monitoring are fitted to a 3 dimensional thin disk model to determine the distance to the megamaser host galaxy. This thesis contributes to the MCP by simulating VLBI data sets through which...

Mark R. Wenger
(:unav)

An evaluation of the differential reporting, treatment completion and personality traits in male batterers

Sonia Latchmei Naraine
The present investigation used a sample of 60 male batterers and their female partners. Men were undergoing court mandated treatment for partner assault. The extent and nature of physical aggression in these relationships was assessed using male and female reports of verbal and physical abuse. It was found that men and women are better able to agree on the frequency of verbally and physically aggressive behaviors that women commit. When examining verbally and physically aggressive...

An analysis of parameters related to the directional instability of rear caster wheelchairs

Timothy J. Collins
A five degree of freedom dynamic model which uses a quasi-static approximation for lateral load transfer effects has been developed as a means of investigating the inherent directional instability associated with rear caster wheelchairs. Using a treadmill and test cart, the dependence of lateral wheelchair tire cornering force on variables such as forward speed, inflation pressure, camber angle, slip angle, and vertical load have been experimentally determined. A model has been developed which predicts wheelchair...

Role of Information in System Justifying Attitudes

Anup Gampa
Wealth inequality in the US is at unprecedented levels and yet we don’t see the kind of resistance to it that one might expect, especially from the oppressed. System Justification Theory (SJT) argues that people are motivated to justify the systems one belongs to—even if the systems are unjust. In fact, SJT postulates that one would become more defensive of the system when inequality in the system is highlighted. I propose, instead, that one’s uncritical...

Studies in the development of royal authority in Argead Macedonia

William Steven Greenwalt
This dissertation examines the elements which defined Argead kingship from the mid-seventh until the late fourth centuries B.C. It begins by reviewing the Argead king list where it is argued that the official reckoning of the dynasty's past was exploited in order to secure the throne against rivals, including those who were Argeads. Chapter Two analyzes the principles of Argead succession and concludes that the current theories on the subject are unsatisfactory in face of...

A comparison of a stimulus prompt and a response prompt with four fading procedures to teach sight words to the moderately and severely retarded

Diane Marie Browder
A comparison was made between a stimulus prompt (picture) and a response prompt (verbal model) to teach functional sight words to 80 institutionalized retarded adults. The four prompting/fading procedures were: 1. Graphic Picture Fading (reducing the brightness and clarity of a picture prompt), 2. Delay Picture Fading (delaying the picture prompt by a few seconds), 3. Delay Word Fading (delaying the verbal model), and 4. Volume Word Fading (reducing the volume of the verbal model)....

The painting of Lorser Feitelson

Diane Moran
THE PAINTING OF LORSER FEITELSON DIANE DEGASIS MORAN This dissertation is a study of the oeuvre of the Los Angeles painter Lorser Feitelson (1898-1978). The paintings are considered in terms of the cultural context, their developmental relationship to the oeuvre as a whole, their formal qualities, their significance in the history of modern art, and the artist'? intentions. In addition, Feitelson's crucial role as champion of modern art in Southern California from the late twenties...

The paper trade and industry in medieval England

David John Duncan
(:unav)

An investigation for differences between teacher-counselors and full-time counselors in the public secondary schools of Virginia

Frederick Ashton Stoutamire
(:unav)

Cultural Determinants of M&A Returns: How Fairness Opinions by Boutique Firms Affect Value

Anna Seitz
In recent years, an increasing amount of attention has been drawn to boutique investment banks as they climb industry league tables. I examine the difference between boutique and full- service firms, and whether cultural distinctions can be seen through the transactions they advise on. I use announcement period returns to determine the effect of differences in an acquirer’s investment bank on transaction returns. First, I find that transactions that have at least one boutique as...

\"Notes on the Taste of Red\"

Landis Grenville
"Notes on the Taste of Red"

The Role of School Leaders in Securing STEM Education for Black Girls

Angel Miles Nash
The cross-case analysis endeavored to examine the perspectives and practices of middle school principals who were leading schools in which a federally-funded, design-based science, technology, engineering, and mathematics (STEM) education grant was being implemented. In the context of a majority minoritized school district, the researcher operationalized the Ontario Leadership Framework (OLF) (Leithwood, 2012) using an intersectional (Crenshaw, 1989, 1991) lens to explore the ways that Black girls’ positionality in the STEM pipeline influenced school leaders....

Reducing Childhood Obesity by Improving Parental Perception of Child Weight Status in a Rural Medical Center

Christy Robinson
The prevalence of obesity in children and adolescents has increased dramatically in the past 40 years. This escalating crisis has reached epidemic proportions as almost one third of the children are considered overweight or obese in the United States. It is especially concerning that obesity is identified in preschoolers which can be predictive of obesity that extends into adolescence and adulthood. Prior research suggests that many parents were unable to recognize their children as being...

Why Boredom is Interesting

Erin Westgate
What is boredom? According to the Meaning and Attentional Components (MAC) model investigated here, boredom signals a lack of meaningful attentional engagement and is the result of (a) an attentional component, composed of mismatches between cognitive demands and available mental resources and (b) a meaning component, composed of mismatches between activities and valued goals (or the absence of valued goals altogether). The MAC model generates a number of novel predictions, including that multiple types of...

Faith in Community: Interracial Discussions and Ecumenical Protestantism, 1945-1960

Connor Kenaston
Historians have described the postwar racial justice activism of predominantly white ecumenical organizations like the Young Women’s Christian Association, Federal Council of Churches, and the Young Men’s Christian Association as “tepid” and “conciliatory.” Drawing on discussion guides, periodicals, and archival materials, this paper shifts the analysis from the organizations themselves to their black staff members. Pairing new social science research with Christian and democratic principles, women and men like Dorothy Height, George Haynes, and Maynard...

The Physicochemical and Systems Level Implications of Using CO2 as a Working Fluid in Hydraulically Fractured Shale Gas Wells

Rodney Wilkins
The rapid growth of natural gas production from unconventional gas shale formations over the past decade has changed the US energy landscape dramatically. This growth has been enabled by directional horizontal drilling and hydraulic fracturing technologies, which allow engineers to access larger portions of a host rock and improve its permeability. The most effective hydraulic fracturing operations use millions of gallons of water at each wellhead. Even though much of this water is returned and...

Agent-based modeling of the glioblastoma tumor microenvironment

Lynette Sequeira
Effects of the tumor microenvironment on cancer progression and malignancy has recently become a common theme when determining therapeutic efficacy and strategies. In fact, in glioblastoma (GBM), the most malignant brain cancer in adults, tumor microenvironmental components have previously been implicated in tumor progression and malignancy. Thus, in this study, we set out to experimentally and computationally recapitulate the effects of the two most abundant stromal GBM cells, astrocytes and microglia, on tumor cell survival...

Applications of the Pfaffian State to Topological Phases

Alexander Sirota
Fractional topological insulators are electronic topological phases in $(3+1)$ dimensions enriched by time reversal and charge $U(1)$ conservation symmetries. The most straightforward series of fermionic fractional topological insulators is analyzed where their bulk quasiparticles consist of deconfined partons that carry fractional electric charges in integral units of $e^\ast=e/(2n+1)$ and couple to a discrete $\mathbb{Z}_{2n+1}$ gauge theory. This thesis proposes massive symmetry preserving or breaking fractional topological insulator surface states. By combining the long-ranged entangled bulk...

New Negro Voices in Virginia: Black Intellectual Leaders' and Hampton Institute's the Southern Workman during the Harlem Renaissance

Judith Wilson
With a particular focus on the 1920s, this paper examines six Southern Workman articles by influential African-American scholars who contributed to New Negro intellectual life: James Weldon Johnson, Carter G. Woodson, Alice Dunbar-Nelson, E. Franklin Frazier, Thomas L. Dabney and Howard Thurman. Though their careers diverged— they became academics, novelists, journalists, activists and a minister— during the 1920s the Workman featured prominently in their intellectual development, and is thus essential to any discussion of their...

Persistence and Resistance: African American High School Teachers and Students During the Long Civil Rights Movement in Charlottesville, Virginia, 1926-1974

Alexander Hyres
This dissertation examines the role of African American high school teachers and students in the struggle for equitable education from 1926-1974 in Charlottesville, Virginia. I argue that teachers and students sought culturally relevant and equitable education through their activism within and beyond the classroom. To be clear, not all African American teachers and students engaged in activism and protest. However, rather than dismiss a whole swath of people due to the inaction of some individuals,...

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