911 Works

A concept rejected : New York's Anglican \"establishment,\" 1693-1715

Cynthia A Kierner
This work analyzes the New York assembly's implementation of the "Ministry Act" of 1693

The Gothic or the monstrous : African American and Caribbean nightmares

Paula Kaye Sato
My dissertation "The Gothic or the Monstrous: African American and Caribbean Nightmares" examines texts and discourses describing a moment in history when life became terrifying to both victimizers and victimized. In the late-eighteenth and early nineteenth centuries, slaveholders disseminated descriptions of rebelling slaves as bloodthirsty cannibals on murderous rampages. In addition, American slaves left narratives that recount life under slavery as a living hell. In her twentieth-century novel Beloved, Toni Morrison visits the psychic trauma...

Agent-based modeling of the glioblastoma tumor microenvironment

Lynette Sequeira
Effects of the tumor microenvironment on cancer progression and malignancy has recently become a common theme when determining therapeutic efficacy and strategies. In fact, in glioblastoma (GBM), the most malignant brain cancer in adults, tumor microenvironmental components have previously been implicated in tumor progression and malignancy. Thus, in this study, we set out to experimentally and computationally recapitulate the effects of the two most abundant stromal GBM cells, astrocytes and microglia, on tumor cell survival...

Simulated Data Sets for the Megamaser Cosmology Project

Jiwon Han
The Megamaser Cosmology Project (MCP) is an NRAO Key Science Project to measure the Hubble Constant, $H_0$, by determining geometric distances to circumnuclear 22 GHz $\text{H}_2\text{O}$ megamasers in galaxies well into the Hubble flow. Two independent measurements from VLBI mapping and single-dish spectral monitoring are fitted to a 3 dimensional thin disk model to determine the distance to the megamaser host galaxy. This thesis contributes to the MCP by simulating VLBI data sets through which...

A tale of two nervous systems: Mechanisms regulating glial migration across nervous system boundaries

Taylor Welsh
A functional nervous system consists of two halves: the central nervous system (CNS) and peripheral nervous system (PNS). Although these two halves are, for the most part, anatomically separate, their communication relies on specialized connections called transition zones (TZ) which form early in development. At these transition zones, axons cross in or out of the spinal cord, connecting CNS and PNS. Some glial cells migrate through TZs as part of normal nervous system development, while...

Identity Matters: Incorporating CLD Students' Identities into the Secondary Classroom

Vonna Hemmler
The number of culturally and linguistically diverse (CLD) students in American public schools has increased in recent years and is only predicted to continue growing. This deserves attention because CLD students all too often experience inequitable classroom contexts that limit their access to curriculum as well as opportunities to have their identities validated in school spaces, both of which research contends is essential for adolescent students’ academic and social development. The three studies presented here...

The role of Macrophage Migration Inhibitory Factor (MIF) in anti-tumor immune responses and metastatic niche formation in breast cancer

Kristen Balogh
Macrophage Migration Inhibitory Factor (MIF) is an inflammatory cytokine expressed by most cell types, which functions as both a cell signaling molecule and a chemokine. MIF is known to have an intrinsic enzymatic activity as a keto-enol tautomerase, however the substrate for this activity in vivo is unknown, and the importance of this activity in the biological function of MIF is still debated. Overexpression of MIF has been found in both the serum and primary...

The Local Practice of Global Aspirations: Ethical Self-Making in Contemporary Chinese Educational Volunteerism

Chenyu Wang
This dissertation explores how the educational development work enacted by foreign-educated Chinese students in rural China reflects contemporary Chinese thinking about the meaning of an educated person. I use ethnography as the methodological orientation, because my goal is to explicate the emic beliefs, knowledge, and practices concerning rural education in China. Data in this dissertation come from a total fourteen-month ethnographic fieldwork in a volunteer education development organization in Beijing and a county high school...

Lovesick: Predictions from Hostile Conflict and Jealousy in Early Adult Romantic Relationships to Sleep, Depression and IL6

Emily Loeb
Romantic relationship hostility has been linked to a variety of health outcomes in marital couples, yet less is known about the role of hostility in health difficulties for young adults over time. The current study examines predictions from several indicators of romantic relationship hostility (observed hostility, jealousy, and reported negativity and conflict) in early adulthood to higher levels of sleep problems, depression, and Interleukin-6 (IL-6) in adulthood. Participants, parents, friends and romantic partners provided observational...

Disruption: Economic Globalization and the End of the Cold War Order in the 1970's

Michael De Groot
This dissertation argues that the economic globalization that swept over the world during the 1970s provides the key to understanding why the Cold War ended. During this decade, industrial states on both sides of the Cold War divide endured a series of shocks to their economic and financial structures. The Western capitalist states adapted to the new economic landscape; the socialist bloc states did not. While the end of the U.S.-Soviet geopolitical and ideological struggle...

Water purification in rural South Africa: ethical analysis and reflections on collaborative community engagement projects in engineering

Eric Harshfield
This paper presents a sustainable development project in which University of Virginia students collaborated with University of Venda faculty, Global Sustainability Club students, and local community members to address water problems in a village in the Venda region of the Limpopo Province, South Africa. The cohort's goal was to implement a sustainable and contextually appropriate water purification and distribution system. The authors present the design and constructed process for a slow sand filtration system intended...

Calcium Based Metallic Glasses: Ductile by Design; Embrittlement by Environment

Andrew Cheung
Metallic glasses made predominately from calcium were, for a short time, of interest for use within the transportation and aerospace industries. This was because of their low density, favorable strength to density ratio, and relatively low materials cost. When the other constituent elements of the Ca glasses are also biodegradable, e.g., Ca-Mg-Zn, then there is interest for their use in the biomedical industry. For these applications, the glasses need to be strong and ductile, or...

Electrochemical Detection of Rapid Adenosine changes in the Brain

Ying Wang
Adenosine is an important molecule in the central nervous system that modulates neurotransmitter release and induces neuroprotective effects during physiological and pathological conditions. Rapid adenosine release has been discovered using fast-scan cyclic voltammetry, which is a paradigm shift for the understanding of the time course of adenosine. However, there are still questions associated with the mechanism of rapid adenosine formation and its functions on a rapid time scale. Here, pharmacological tests as well as transgenic...

Studies in the development of royal authority in Argead Macedonia

William Steven Greenwalt
This dissertation examines the elements which defined Argead kingship from the mid-seventh until the late fourth centuries B.C. It begins by reviewing the Argead king list where it is argued that the official reckoning of the dynasty's past was exploited in order to secure the throne against rivals, including those who were Argeads. Chapter Two analyzes the principles of Argead succession and concludes that the current theories on the subject are unsatisfactory in face of...

A comparison of a stimulus prompt and a response prompt with four fading procedures to teach sight words to the moderately and severely retarded

Diane Marie Browder
A comparison was made between a stimulus prompt (picture) and a response prompt (verbal model) to teach functional sight words to 80 institutionalized retarded adults. The four prompting/fading procedures were: 1. Graphic Picture Fading (reducing the brightness and clarity of a picture prompt), 2. Delay Picture Fading (delaying the picture prompt by a few seconds), 3. Delay Word Fading (delaying the verbal model), and 4. Volume Word Fading (reducing the volume of the verbal model)....

The painting of Lorser Feitelson

Diane Moran
THE PAINTING OF LORSER FEITELSON DIANE DEGASIS MORAN This dissertation is a study of the oeuvre of the Los Angeles painter Lorser Feitelson (1898-1978). The paintings are considered in terms of the cultural context, their developmental relationship to the oeuvre as a whole, their formal qualities, their significance in the history of modern art, and the artist'? intentions. In addition, Feitelson's crucial role as champion of modern art in Southern California from the late twenties...

The paper trade and industry in medieval England

David John Duncan

The Physicochemical and Systems Level Implications of Using CO2 as a Working Fluid in Hydraulically Fractured Shale Gas Wells

Rodney Wilkins
The rapid growth of natural gas production from unconventional gas shale formations over the past decade has changed the US energy landscape dramatically. This growth has been enabled by directional horizontal drilling and hydraulic fracturing technologies, which allow engineers to access larger portions of a host rock and improve its permeability. The most effective hydraulic fracturing operations use millions of gallons of water at each wellhead. Even though much of this water is returned and...

Of Fals Ymaginacioun: Poetic Hypocrisy in Anglo-Arabic Letters, 700-1400

Sherif Abdelkarim
Broadly defined as the significant break between word, deed, appearance, or intention, hypocrisy might be the most overlooked and least understood “sin” in medieval literature. An odd one out, this moveable vice defies canonical classification: hamartiologists have attached it to Pride, Envy, Vainglory, Avarice. Seldom is hypocrisy named hypocrisy. Yet the vice’s active agent, the hypocrite, runs rampant in public, wearing a gaudy array of cultural and ethical markers. What gives literary hypocrites notable edge...

Persistence and Resistance: African American High School Teachers and Students During the Long Civil Rights Movement in Charlottesville, Virginia, 1926-1974

Alexander Hyres
This dissertation examines the role of African American high school teachers and students in the struggle for equitable education from 1926-1974 in Charlottesville, Virginia. I argue that teachers and students sought culturally relevant and equitable education through their activism within and beyond the classroom. To be clear, not all African American teachers and students engaged in activism and protest. However, rather than dismiss a whole swath of people due to the inaction of some individuals,...

Characterizing Rotations in Thermally-Driven Winds Above a Valley Floor Using Observations From the 21 August 2017 Solar Eclipse and a Climatological Record

Ross Palomaki
Thermally-driven winds in complex terrain are characterized by a diurnal cycle with upvalley winds during the day, downvalley winds at night, and transitional periods around sunrise and sunset. These winds are important for air pollution dispersion in valleys, and can also affect weather patterns on a regional scale. However, the winds are not always resolved in weather and climate models, and poor parameterization schemes result in inaccurate weather forecasting over mountainous regions. Observations of thermally-driven...

Fast and Scalable Joint Estimators for Learning Sparse Gaussian Graphical Models from Heterogeneous Data with Additional Knowledge

Beilun Wang
Understanding and quantifying variable graphs from heterogeneous samples is a fundamental and urgent analysis task thanks to the data explosion in many scientific domains. Such variable graphs can significantly improve network-driven studies like understanding genetic or neural pathways or providing valuable tools for the discovery of therapeutic targets or diagnostic markers. One typical approach is to jointly estimate K different but related conditional dependency graphs through a multi-task formulation of the sparse Gaussian Graphical Model...

Jazz Neoclassicism and Racial Uplift, 1970-2007

Steven Lewis
Jazz’s neoclassical turn in the late 1970s, and the subsequent arrival of the young musicians labeled the “Young Lions” in the 1980s and 1990s, was one of the most important developments in late 20th century jazz history. This dissertation contextualizes this moment in jazz history and jazz criticism within the broader context of African American social and political thought. I argue that, in their cultural politics, Wynton Marsalis, Albert Murray, and Stanley Crouch—the ideological architects...

Creating Fingerprint Databases and a Bayesian Approach to Quantify Dependencies in Evidence

Maria Tackett
In 2009, the National Research Council issued "Strengthening Forensic Science in the United States: A Path Forward" about the need for more scientific rigor in forensic science. Since then, there has been an effort to make the methods used to analyze forensic evidence more objective, in part through the use of statistics to interpret the evidence. With Lindley (1977) as a guide, this research focuses on two aspects of statistics in forensic science. The first...

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