1,026 Works

Examining Metabolism in Seagrass Meadows: Trends in Respiration and Non-Dissolved Gas Ebullition

Ieva Juska
Seagrass meadows provide many valuable ecosystem services, including carbon sequestration and storage of ‘blue carbon’. Enhancing carbon cycling through seagrass restoration can thus act as a nature-based solution for climate change, as these ecosystems naturally remove carbon dioxide from the atmosphere through their high rates of productivity. Estimated metabolic values such as Gross Primary Productivity (GPP), Respiration (R), and Net Ecosystem Metabolism (NEM) are used in quantifying in situ carbon sequestration in seagrass meadows and...

Compton Polarimetry for Neutral Weak Form Factor Measurements in 208Pb and 48Ca

Allison Zec
Atomic nuclei contain a number of protons and neutrons. Most heavy nuclei contain more neutrons than protons in order to remain stable. The nuclear proton distribution can be measured via elastic scattering of charged particles, but the neutron distribution remains poorly constrained. Nuclear structure theory also predicts a "neutron skin" ΔRnp where the mean radii of neutrons in the nucleus exceeds that of protons. Two experiments were run in 2019 and 2020 to measure the...

A partial study of \"The early South-English legendary, or Lives of saints\"; MS. Laud, 108, in the Bodleian Library

Edwin Lake Setzler
A study of the grammar and the dialect (vowel changes) of the "Early south-English Legendary", and gives a general idea of peculiarities of the manuscript.The paper is based on a study of every word in a selected passage of ~500 lines of the Manuscript covering the stories "St. Mathew", "St. Leger", "St. Fey", "Endlevene Þousand of Virgines, and eight line of "St. Katerine".

Identification of MHC-Associated Peptides and Phosphopeptides Presented in Various Diseased Cells by Tandem Mass Spectrometry

Xi Peng
Major histocompatibility complex (MHC) class I and II molecules are involved in the presentation of antigens to T cells, which can initiate an immune response upon recognition of abnormal peptide sequences and modifications. Specifically, phosphopeptides resulting from aberrantly increased protein phosphorylation in cancer are proposed as potential cancer-specific targets for developing novel immunotherapeutic treatments. However, it remains as a challenge to accurately identify these peptide sequences and to localize modification sites due to factors including...

Leveraging Proteomic Strategies to Analyze Post-Translational Modifications and Membrane Proteins

Maria Panepinto
This dissertation details three projects that apply tandem mass spectrometry to analyze purified proteins. There are three strategies that can be used to approach proteomic analysis: intact, limited digestion, and traditional digestion. All three of these projects are unified in that at least two of these strategies was required to achieve their goal. This dissertation demonstrates that these approaches are much more powerful and provide more information in combination than they do alone. The first...

Brass rank and gold rings : class, race, gender, and kinship within the Army community

Margaret Cecchine Harrell
Under traditional United States military system, officers were married men whose wives were expected to perform considerable unpaid labor, while enlisted men were assumed to be young unmarried men. To the extent that enlisted men, even the more senior enlisted personnel, were married, their wives and families were not generally acknowledged or supported by the Army; and they were separated from the officers' families by a considerable barrier of social class. In contrast, officers' wives...

The tax system of North Carolina

Oscar Arthur Kirkman
Foreward: Printed material in any quantity on taxation in North Carolina has never been collected. Very little information other than Public Documents is available. North Carolina today is attracting attention throughout the world. There have been many developments which come only from the manipulation of great resources by a great people. The purpose of this thesis is an effort to get into the subject of taxation in North Carolina and to analyze the methods being...

Jane Austen: the determining influences of her life on her works

Julia Ellen duVal
A study of the reflections of Jane Austen's life in her novels.

The Melismos: The Child as Sacrifice in Byzantine Art

Barbara Sweeney Mustain
This paper is a history of the Melismos. It is a documentation of the appearance, dispersal, modification and decline of that visual form, It is, above all, a search for the meaning of the Melismos. It follows the fascinating history of the idea of the child sacrifice, seeking to reveal the special circumstances which led to the appearance of that idea as a work of art, and it attempts to document the subtle shifts in...

Resistance of Neisseria gonorrhoeae to nutritional immunity protein-mediated zinc limitation during epithelial infection

Jocelyn Ray
Neisseria gonorrhoeae (Gc) is an obligate human pathogen that infects mucosal epithelia to cause the common sexually-transmitted infection (STI) gonorrhea, and antimicrobial-resistant Gc is an urgent public health threat. Gonorrhea has the potential to cause serious sequelae when untreated, especially in women, who may be asymptomatic and unaware that they are infected. The initial site of infection of the female reproductive tract is usually the cervix. In order to establish infection, Gc must attach to...

The role of Notch signaling in regulating neural stem cell quiescence and termination during development

Chhavi Sood
Multipotent cells called neural stem cells (NSCs) proliferate to produce a functional adult neural circuitry and maintain tissue homeostasis during development and in adulthood. NSCs can divide either symmetrically to increase stem cell numbers or asymmetrically to produce different types of progenies. During development, most NSCs terminate their proliferation and neurogenesis becomes restricted and in the adult tissue, NSCs are maintained in a state of quiescence in neurogenic niches. The NSC proliferation versus quiescence decisions...

Designing a Cost-Effective and Accurate Laser Cutter That Serves a Market Niche; Plastics and Their Effects on Society

Christopher Dauber
Rapid prototyping is an emergent field that allows for the physical validation of CAD models in 3D. Originally used by architects and designers to make scale models of products and buildings, it has since grown to become a broad field that borrows many techniques from areas as diverse as modelmaking, special effects, engineering, architecture, sculpture and art. Rapid prototyping makes use of a variety of materials to achieve its goals, but it benefits especially from...

Cyber-Physical Systems and National Security

Enkhbilig Batsukh
This thesis portfolio is comprised of research into the cyberphysical systems that define the global economy, from the consumer appliance to defense technology networks. On a societal scale, many Americans utilize cyberphysical systems as a matter of course – few consider the level of integration these tools have achieved to be particularly abnormal. Computerized control systems have contributed to the development of a vast array of devices that simplify or enhance everyday life from smart...

Moral Distress Mobile Application; An Analysis of Moral Distress and Methods Used to Combat It

Keegan Pezzella
Nursing is not an easy profession. It involves long hours, hard moments, and stresses not seen in many other professions. A significant, but understudied, problem faced by nurses is moral distress. This is a phenomenon characterized by knowing the ethical solution but being unable to pursue it, typically due to institutional constraints. In order to better combat and understand the phenomenon of moral distress, we undertook the task of creating a mobile app that would...

FloodWatch: A Mobile Application for Real Time Flood Response and Analysis; Understanding the Non-Technical Challenges of Gray Flooding Solutions in Coastal Cities

Adriel Kim
Coastal flooding in cities is on the rise due to factors such as climate change, changes in precipitation, and land subsidence. Ho Chi Minh City, among the top flood-prone cities, is predicted to be submerged along with most of southern Vietnam by 2050. A critical step to addressing this problem is through collecting flood data. My capstone project, FloodWatch, fills in this step by serving as a platform for collecting user-generated flood data. At the...

Legacy Code: Two Changes Needed to Redistribute 18-Year-Old Software; Identifying Motivations Behind Player Toxicity in Competitive Settings

Parth Raut
My technical and STS topics address problems that are completely different from one another. My technical topic highlights my experience working as a software engineering intern during the summer of 2021. The foundation of my internship relied on the idea of encryption of data in the context of licensing software. On the other hand, my STS topic provides an analysis as to why toxic behavior in video games exists. The foundation of my STS topic...

Dust Scattering in Protoplanetary Disks

Daniel Devlin
Using the Monte Carlo radiative transfer method, the following code, written in C++ and building on the Athena++ framework, adds a program for dust scattering simulations. We then compare the output of the code to a tested dust simulation code written in FORTRAN. For this comparison we use a problem generator which simulates a protoplanetary disc of varying density which surrounds a binary star system with the stars having different luminosities. We then discuss the...

Issues of Localized Corrosion in Additively Manufactured 316L Stainless Steel

Duane Armell Macatangay
Additive manufacturing (AM) is a class of material fabrication methods that has exciting applications in the production of metal alloys such as austenitic stainless steels. In addition to opportunities in material and energy use reduction, the AM process offers opportunities in microstructure control and the refinement of mechanical properties such a strength, ductility, and toughness. AM processes such as laser powder bed fusion (LPBF) and direct energy deposition (DED) create materials with complex microstructures that...

Production of Biodiesel from Algae; Societal Players that Contributed to COVID-19 Vaccine Trust

Kazu Yoshizaki
This capstone portfolio contains two research topics: a technical research component and an STS research component. The technical research aims to design a production facility for biodiesel through algae cultivation. This research can help illustrate the economic feasibility of a large-scale algae biofuel production facility, as well as address the technical challenges in designing an end-to-end process to extract energy from biomass. The STS research aims to analyze how the interactions and relationships between different...

The Design of Lipid Nanoparticles for Delivery of RNA Therapeutics as a Treatment for Acute Myeloid Leukemia; Scientific Integrity: Performing Pre-Clinical Research the Right Way

Colin Haws
Biomedical research is one of humanity’s most powerful tools. When used correctly, novel pre-clinical findings may lead to the development of life-saving therapies. Transformational medicines such as nanoparticle mediated drug delivery have the potential to provide improved treatments for patients with serious illnesses such as Acute Myeloid Leukemia (AML). The technical portion of the proposed work examines a lipid nanoparticle based combinatorial approach with chemotherapies as a novel treatment for AML patients. Unfortunately, some researchers...

Hypersonic Atmospheric Reentry Deceleration Experiment (HARD-E); Complacency around Failure in the US Space Program

Noah Dunn
In space travel missions, there is an array of both technical and non-technical factors that determine mission success. Space travel itself is a turbulent process where vehicles and humans travel in extreme conditions for extended periods of time, so intricate engineering efforts are designed to ensure safe passage. However, there are many social, managerial, and political factors that influence the success of missions and must be considered during the space mission process. Despite the best...

Peg Solitaire: A New Algorithm for an Old Game; The Emergence and Obsolescence of Web Frameworks

Michael Starego
Advancements in computer science can have a profound impact on the world of puzzles and games. Using computers, solutions to puzzles like the centuries-old board game peg solitaire can be generated in a fraction of a second. New techniques for solving and analyzing these puzzles can shed new light on the mathematics underlying them. Likewise, growth in the field of computing has led to the sudden emergence and rapid expansion of the video game industry....

Intimate Partner Violence Assessment Program Evaluation

Susanna Pruangkarn
Intimate partner violence (IPV) refers to the violence or patterns of abusive behaviors between intimate partners with 17 % of men and 33 % of women experiencing IPV (Ahmed et al., 2017). Despite the prevalence of IPV in the general population, compliance with national standards for IPV screening is inconsistent. Surprisingly, only 66 % of hospitals across the US screen for IPV in their EDs (Delgado et al., 2011). The purpose of this project was...

How Wearable Sensing Can Be Used to Monitor Patient Recovery Post ACL Reconstruction; The Impact of Gender Inequality in Clinical Research for Anterior Cruciate Ligament Tears

Sydney Lawrence
Over 100,000 patients in the United States annually elect to have Anterior Cruciate Ligament reconstruction (ACLR) in hopes of returning to pre-injury level of activity. In the first two years following an ACLR, patients are at their highest risk for re-injury to both the repaired and contralateral knee. With the use of wearable ubiquitous sensors, the technical project monitors patients post-ACLR and how they can be used to aid medical decision-making regarding rehabilitation progressions and...

The Development and Evaluation of a Shallow Ground Loop Design for Ground Source Heat Pumps (GSHPs); The Role of Socio-Cultural Influences on Electric Vehicle Adoption in the Modern American Market

Kara Koopman
Climate change is often considered the defining crisis of the 21st century. The world is running out of time to reduce greenhouse gas (GHG) emissions and constrain global warming enough to avoid truly catastrophic damage. This portfolio examines challenges to the adoption of two emerging sustainable technologies – ground source heat pumps and electric vehicles – which have the potential to greatly reduce emissions. Ground source heat pumps (GSHPs) are more efficient than traditional systems...

Registration Year

  • 2022
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  • University of Virginia
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