64,852 Works

Studies on acceptance, evaluation and impact of the Cologne program “Research and Medical Studies”

Sören Moritz, Abdul Halawi, Charlotte Proksch, Jan-Michael Werner, Mats Paulsson, Markus Rothschild & Christoph Stosch
Introduction: The curricular implementation of events (or programs) for science-related training in human medicine has been on the agenda of the medical faculties since the publication of the Federal-State Working Group [ref:1]. The Medical Faculty of the University of Cologne developed and established a systematic, longitudinal science curriculum together with the start of the model curriculum in human medicine in 2003. Here, we investigate the questions of whether the described (para-) curricular elements are accepted...

Measuring competency-relevant knowledge in the competency-oriented student progress test

Andreas Möltner, Stefan Wagener & Mirka Burkert
Background: Since 2013 a competency-oriented student progress test (SKPT) has been administered at a number of German medical schools. The questions are generated on the basis of a two-dimensional blueprint, on which one axis contains the five competency domains – communicative competence (CO), practical clinical competence (CP), theoretical clinical competence (CT), scientific competence (SC), and professional decision-making competence (PR) – that form part of the competency model of the National Competency-based Catalogue of Learning Objectives...

Development of the Greifswald questionnaire for the measurement of interprofessional attitudes

Sandra Lange, Maud Partecke, Konrad Meissner, Ulrike Heß & Anette Hiemisch
Introduction: The implementation of interprofessional education (IPE) could be a potential approach to dealing with increasing complexity in health care. And thus, encouraging interprofessional collaborations to minimize errors in patient care. However, empirical evidence regarding the effectiveness of IPE is inconclusive. One reason for this is a lack of valid and reliable evaluation instruments. This study aims to illustrate the first steps of the development and validation of a German evaluation instrument for the measurement...

Acknowledgement to the reviewers of GMS Journal for Medical Education

Martin R. Fischer & Götz Fabry
[for full text, please go to the a.m. URL]

Does the tutors' academic background influence the learning objectives in problem-based learning?

Matthaeus C. Grasl, Karl Kremser, Jan Breckwoldt & Andreas Gleiss
Background: Problem-based learning (PBL) is an essential element of the curriculum of the Medical University of Vienna (MUV) and is performed in an eight steps model with: clarifying, defining, analysing, shifting & sorting, identifying learning objectives, going to learn and coming back to talk and feedback. With an annual intake of up to 740 students the MUV has to recruit PBL tutors from various academic backgrounds including undergraduate near-peer students. Therefore, we were interested to...

Expectations, training and evaluation of intensive care staff to an interprofessional simulation course in Germany – Development of a relevant training concept

Markus Flentje, Lars Friedrich, Hendrik Eismann, Wolfgang Koppert & Heiner Ruschulte
Objective: Increasingly, intensive care units (ICU) are operated by teams of physicians and nurses with specialist training in anaesthesia and intensive care. The aims of our study were to evaluate any prior experience, expectations and the requisites for interprofessional ICU simulation-based training (SBT), and to evaluate a newly designed training course incorporating these findings. Methods: The study was laid out as a cross-sectional study and is projected in three steps. First, questionnaires were sent out...

Possibilities of dissemination of specialist knowledge and acting capacity in the field of child protection in medicine: a qualitative survey

Anna Maier, Miriam Rassenhofer, Ulrike Hoffmann & Jörg M. Fegert
Objective: The shortage of skilled workers and overloaded schedules make further training of health professionals difficult. In addition, child protection is not a systematic part of medical studies. The evaluation of an online course on child protection in medicine reveals positive feedback but also that the main reason for participants aborting the course is lack of time. Dissemination, as an active, targeted spreading of knowledge, can help to further spread knowledge about child protection in...

Letter to the readers: proposal for a new year's resolution

Wolf Hautz
[for full text, please go to the a.m. URL]

Development, implementation, and evaluation of a curriculum for medical students on conflicts of interest and communicating risk

Nicole Deis, Cora Koch, Nadine Dreimüller, Eva Gaitzsch, Jens Weißkircher, Jana Jünger & Klaus Lieb
Background: Insufficient risk competence of physicians, conflicts of interests from interactions with pharmaceutical companies, and the often distorted presentation of benefits and risks of therapies compromise the advising of patients by physicians in the framework of shared decision-making. An important cause of this is that teaching on this subject is mostly lacking, or fragmented when it does take place [ref:1], [ref:2], [ref:3], [ref:4]. Even though the German National Competence-Based Catalog of Learning Goals in Medicine...

Prof. Peter Erich Dieter, PhD: 22.02.1952 – 25.12.2019

Eckhart G. Hahn
[for full text, please go to the a.m. URL]

Protecting children across borders – child protection in an international context (Germany/Switzerland) as an interprofessional teaching unit

Franziska Krampe, Stephanie Peters, Christine Straub & Sebastian Bode
Introduction: Interprofessional collaboration (IPC) in everyday clinical practice is a prerequisite for good patient care but currently this is not sufficiently anchored in the education of health care professionals. Project description: A course on child protection in the interprofessional and international domain was established at the Medical School, University of Freiburg. In this course, students of medicine, nursing science and social work acquire skills for successful interprofessional cooperation. Its participants learn across professional and national...

The influence of prompts on final year medical students' learning process and achievement in ECG interpretation

Markus Berndt, Franziska Thomas, Daniel Bauer, Anja Härtl, Inga Hege, Stefan Kääb, Martin R. Fischer & Nicole Heitzmann
Objective: ECG interpretation is prone to errors that can lead to relevant misdiagnoses and incorrect treatment. Prompts are one way in lectures to encourage learning from one’s own mistakes and to reduce error rates. Prompts are measures such as questions, hints, and suggestions of content-related or metacognitive nature, which can lead to self-explanation in the learner and thus to a deeper understanding of an issue. The aim of the study was therefore to investigate whether...

Trocar-assisted, flanged sutureless scleral-fixated intraocular lens implantation combined with silicone oil injection after penetrating keratoplasty surgery

Remzi Karadag, Guler Kilic, Aylin Ardagil & Ahmet Demirok
We describe a combined technique of trocar-assisted sutureless scleral-fixated intraocular lens implantation and silicone oil injection at the same session. Two 3 mm scleral tunnels were created 2 mm away from and parallel to the limbus with the 23-gauge vitrectomy trocars entering the sclera transconjunctivally at an angle of approximately 10° at the 3 o’clock and 9 o’clock meridians. After the 3-piece foldable IOL was delivered to the anterior chamber through the corneal incision, the...

Descemet’s membrane endothelial keratoplasty in aphakic and vitrectomized eye

Remzi Karadag, Veysel Aykut, Fehim Esen, Halit Oguz & Ahmet Demirok
Objective: To report a new technique for Descemet’s membrane endothelial keratoplasty (DMEK) in aphakic and vitrectomized eyes. Case description: A 56-year-old man presented with corneal decompensation in the left eye after combined pars plana vitrectomy and lensectomy for the management of a traumatic eye injury. DMEK graft and recipient bed were prepared as regular. The posterior half of the donor stroma was dissected with a crescent knife to form a temporary stromal barrier tissue. The...

Acute stromal keratitis in clinics – are we missing microsporidia?

Javed Hussain Farooqui, Manisha Acharya, Arpan Gandhi & Umang Mathur
Purpose: To report 3 cases of microsporidial stromal keratitis presenting as a diagnostic dilemma to a tertiary eye care center in north India. Methods: Three eyes of 3 patients underwent therapeutic keratoplasty for microsporidial stromal keratitis. A decision for early surgery was taken as the patients were not responding to conventional medical management and were worsening clinically. The diagnosis of microsporidia was made by corneal scraping and confirmed on histopathological evaluation of the corneal button....

Untersuchung der Datenvollständigkeit im Vorfeld der Sekundärdatenanalyse am Beispiel der wissenschaftlichen Nutzung hausärztlicher Behandlungsdaten

Falk Schlegelmilch, Eva Hummers & Iris Demmer
Background: Treatment data from general practitioners (GP) in private practice have great potential for research into diagnostics, therapy and quality of care. The quality of these data influences not only the primary research results, but also the results of later secondary data analyses, but then for other research questions. Completeness and availability of data at the time of data collection are important quality characteristics that depend on medical documentation and technical data export. Using GP...

TGFBI ist ein Biomarker für die Erkennung von high-grade Urothelkarzinomen im Urin und reguliert die Proliferation und Migration von Blasenkrebszellen

Kerstin Lang, Florian Roghmann, Joachim Noldus, Thomas Brüning & Heiko U. Käfferlein
Einleitung: Wir haben transformierendes Wachstumsfaktor beta induziertes Protein (TGFBI) als einen vielversprechenden neuen Biomarker im Urin für high-grade und muskelinvasive Urothelkarzinome (UC) identifiziert, und gezeigt, dass die Sezernierung von TGFBI biologische Funktionen von Blasenkrebszellen[zum vollständigen Text gelangen Sie über die oben angegebene URL]

Assoziation von KRT20 und KRT5 mit dem Ansprechen auf eine neoadjuvante Chemotherapie bei Patienten mit muskelinvasivem Blasentumor

Florian Roghmann, Moritz Reike, Ralph Wirtz, Maximilian Kriegmair, Philipp Erben, Karl Tully, Veronika Weyerer, Markus Eckstein, Arndt Hartmann, Felix Wezel, Christian Bolenz, Andrea Tannapfel, Joachim Noldus & Hendrik Jütte
Einleitung: Patienten mit muskelinvasivem Urothelkarzinom der Blase (MIBC), die vor einer radikalen Zystektomie (RC) eine neoadjuvante Chemotherapie (NAC) erhalten haben, zeigen ein verbessertes Gesamtüberleben. Die beste Prognose haben in der Regel die Patienten mit einem kompletten pathologischen[zum vollständigen Text gelangen Sie über die oben angegebene URL]

Assoziation von ESR1- und HER2-mRNA-Expression mit dem Ansprechen auf eine neoadjuvante Chemotherapie bei Patienten mit muskel-invasivem Blasentumor

Hendrik Jütte, Moritz Reike, Ralph Wirtz, Maximilian Kriegmair, Philipp Erben, Karl Tully, Markus Eckstein, Veronika Weyerer, Arndt Hartmann, Felix Wezel, Christian Bolenz, Andrea Tannapfel, Joachim Noldus & Florian Roghmann
Einleitung: Patienten mit muskel-invasivem Urothelkarzinom der Blase (MIBC), die vor einer radikalen Zystektomie (RC) eine neoadjuvante Chemotherapie (NAC) erhalten haben, zeigen ein verbessertes Gesamtüberleben. Die beste Prognose haben in der Regel die Patienten mit einem kompletten pathologischen[zum vollständigen Text gelangen Sie über die oben angegebene URL]

Eine empirische Studie zur operativen Therapie der symptomatischen Urolithiasis mittels Ureterorenoskopie (URS) in der Bundesrepublik Deutschland – FaST 4

Rueveyde Sahin, A. Reicherz, J. Noldus & P. Bach
Hintergrund: In Deutschland werden pro Jahr rund 1,2 Millionen Patienten mit einer symptomatischen Urolithiasis operativ von rund 200 urologischen Kliniken versorgt. Ziel dieser landesweiten Befragung war es, die therapeutischen Behandlungsmodalitäten der Urolithiasis auf der Grundlage eines selbstverfassten[zum vollständigen Text gelangen Sie über die oben angegebene URL]

Evaluation präoperativer Prädiktoren für einen positiven Resektionsstatus bei radikaler Prostatektomie

Karl Tully, Maximilian Schulmeyer, Moritz Reike, Julian Hanske, Nicolas Von Landenberg, Rudolf Moritz, Marko Brock, Hendrik Jütte, Christian von Bodman, Joachim Noldus, Florian Roghmann & Rein-Jüri Palisaar
Einleitung: Ein positiver Resektionsstatus (R+) nach radikaler Prostatektomie geht mit einem schlechteren krankheitsspezifischen Überleben einher. Die intraoperative Schnellschnittdiagnostik ist eine Möglichkeit, die Rate an R+ resezierten Tumoren zu verringern. Aktuelle Studien [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Ergebnisse der rigiden, perinealen 3 Tesla MRT-fusionierten Prostatastanzbiopsie bei 117 Patienten in einem Prostatazentrum (DPVZ)

Mirko Maek, Moritz Gmelin, Sven Hauser & Bernhard Planz
Einleitung: In dieser Studie werden die Daten der MRT-fusionierten Prostatastanzbiopsie (PBx) in einem Prostatazentrum anhand einer prospektiven Studie ausgewertet. In der S3-Leitlinie der DGU zur Diagnostik des Prostatakarzinoms (PCa) stellt eine MRT-fusionierte PBx in der Primärdiagnostik keine[zum vollständigen Text gelangen Sie über die oben angegebene URL]

Präoperative Prädiktoren für intraoperativen Nerverhalt bei Radikaler Prostatektomie

Karl Tully, Rudolf Moritz, Maximilian Schulmeyer, Moritz Reike, Julian Hanske, Nicolas von Landenberg, Marko Brock, Hendrik Jütte, Christian von Bodman, Joachim Noldus, Florian Roghmann & Rein-Jüri Palisaar
Einleitung: Das funktionelle Ergebnis nach radikaler Prostatektomie ist ein postoperatives Qualitätsmerkmal. Ein entscheidender Faktor für ein suffizientes funktionelles Ergebnis ist der bilaterale Erhalt des neurovaskulären Bündels. Ziel dieser Arbeit ist die Evaluation präoperative[zum vollständigen Text gelangen Sie über die oben angegebene URL]

Der Nachweis der Expression von 3 Genen kann zur Identifizierung eines inzidentellen Prostatakarzinoms bei einer radikalen Zystektomie wegen Blasenkarzinom dienen

Konstantin Richter, Barbara Köditz, Melanie von Brandenstein, Jochen Fries & Axel Heidenreich
Einleitung: Prostatakarzinom (PCa) ist der am häufigsten diagnostizierte maligne Tumor in Männern. Harnblasenkarzinom ist die zwei häufigste Tumorerkrankung des Urogenitaltraktes. Die Hauptaufgabe dieser Studie war die Identifizierung verschiedener Genexpressionen in PCas während[zum vollständigen Text gelangen Sie über die oben angegebene URL]

Der Einfluss vorheriger Therapien auf das Gesamtüberleben bei mCRPC-Patienten, die eine Lu-PSMA-617-Therapie erhalten. Eine retrospektive multizentrische Studie von WARMTH

Hojjat Ahmadzadehfar, Kambiz Rahbar, Richard Baum, Carolin Gerke, Clemens Kratochwil, Harun Ilhan, Mike Sathekge, Levent Kabasakal, Francisco Osvaldo Garcia-Perez, Kalevi Kairemo, Masha Maharaj, Diana Paez & Irene Virgolini
Einleitung: Der Einfluss früherer Therapien, insbesondere der Chemotherapie, auf das Gesamtüberleben (OS) von Patienten mit kastrationsresistentem Prostatakarzinom (CRPC), die mit Lu-PSMA-617 behandelt wurden, wurde kontrovers diskutiert. Daher führte WARMTH eine multizentrische Analyse[zum vollständigen Text gelangen Sie über die oben angegebene URL]

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