158 Works

Pigment Yellow 12, Pigment Yellow 13, Pigment Yellow 83

Andrea Hartwig &
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated Pigment Yellow 12 [6358-85-6], Pigment Yellow 13 [5102-83-0] and Pigment Yellow 83 [5567-15-7] considering all toxicological end points. Depending on their intended use, the pigments are produced in different sizes with a d50 ranging from 15 to 250 nm. In technical applications, particles smaller than 100 nm are called nanoparticles. By definition, pigments are not soluble in...

Observational study over 8-year period evaluating microbiological characteristics and risk factor for isolation of multidrug-resistant organisms (MDRO) in patients with healthcare-associated infections (HAIs) hospitalized in a urology ward in Urogenital Infections and Inflammations

José Medina-Polo, Javier Gil-Moradillo, Alejandro González-Díaz, Pablo Abad-López, Rocío Santos-Pérez de la Blanca, Mario Hernández-Arroyo, Helena Peña-Vallejo, Julio Téigell-Tobar, Cristina Calzas-Montalvo, Prado Caro-González, Natalia Miranda-Utrera & Ángel Tejido-Sánchez
Objective: To analyze, in a urology ward, the prevalence and characteristics of healthcare-associated infections (HAIs) due to multidrug-resis­tant organisms (MDRO). Methods: We carried out an observational study from 2012 to 2019, evaluating MDRO among patients with HAIs, who were hospitalized in the urology ward. MDRO include Pseudomonas spp., resistant to at least three antibiotic groups, extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae or those resistant to carbapenems, and Enterococcus spp. resistant to vancomycin. Results: Among patients with...

Kohlenmonoxid – Addendum zur Reevaluierung des BAT-Wertes

Britta Brinkmann, Rüdiger Bartsch, Christoph van Thriel, Hans Drexler, Andrea Hartwig &
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated the biological tolerance value (BAT value) of carbon monoxide (CO) [630-08-0]. Exercising healthy test persons became significantly faster exhausted at CO exposures resulting in a CO-Hb content of 3.35 to 5.1%. This was only observed with very high physical activity (minute volume of 100 l/min) which is much higher than that assumed to be realistic in workplaces...

Dichloroacetic acid and its salts

Andrea Hartwig &
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated dichloroacetic acid [79-43-6] to derive a maximum concentration at the workplace (MAK value) and to review its carcinogenicity classification. The critical effects are irritation, carcinogenicity in the liver of rats and mice as well as neurotoxicity. After oral application, dichloroacetic acid or its sodium salt has tumour-promoting effects and is carcinogenic in the liver of rats and...

Triphenylphosphat

Andrea Hartwig &
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated triphenyl phosphate [115-86-6] considering all toxicological end points. Triphenyl phosphate is not neurotoxic in hens and rats and not irritating to the eyes and skin of rabbits. In a 13-week toxicity study with rats, hepatocellular hypertrophy and follicle cell hypertrophy in the thyroid gland started to be not adversly induced at a triphenyl phosphate dose of 105...

Gadolinium – Evaluation of study results in biological material

Bernhard Michalke, Hans Drexler, Andrea Hartwig &
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated the background concentration of gadolinium [7440-54-2] in occupationally not exposed persons of the general population without gadolinium application for magnetic resonance imaging (MRI). Available publications are described in detail.In total, only few publications on the background exposure to gadolinium could be found, some of which used different analytical methods and different sample matrices (urine, blood, serum). Gadolinium...

List of MAK and BAT Values 2021

Di-tert-dodecyl pentasulfide

Andrea Hartwig &

o-Toluidine – Addendum for re-evaluation of the BAR

Katrin Klotz

1-Methoxypropylacetate-2

Barium compounds (soluble)

Andrea Hartwig &

Acrylonitrile – Addendum for evaluation of a BAR

Thomas Kraus, Jürgen Angerer, Michael Bader & Thomas Schettgen

Tetrachloromethane – Addendum for re-evaluation of the BAT value

Karl Heinz Schaller & Hermann Maximilian Bolt

Benzol, Benzylchlorid und Toluol – Bestimmung von S-Phenylmerkaptursäure und S-Benzylmerkaptursäure in Urin mittels LC-MS/MS

Thomas Schettgen, Anita Musiol, Gerhard Scherer & Katharina Sterz

Isopropyl benzene (cumene) – Evaluation of a BAT value

Udo Knecht

Iod und anorganische Iodide – Bestimmung von Iodid in Serum/Plasma oder Urin mittels Ionenchromatographie‑ICP‑MS

Bernhard Michalke, Jackie Morton, Thomas Göen, Andrea Hartwig &

Acrylonitrile – Addendum for re-evaluation of EKA and BAR

Thomas Jäger, Hans Drexler, Andrea Hartwig &

Antimon und seine anorganischen Verbindungen mit Ausnahme von Antimonwasserstoff

Andrea Hartwig &

Mangan – Bestimmung von Mangan und seinen anorganischen Verbindungen in der Luft am Arbeitsplatz mittels Atomabsorptionsspektroskopie (AAS)

Claudia Schuh, Michael Kirchner, Ralph Hebisch, Andrea Hartwig &

Neurotoxische Esterase (neuropathy target esterase)-Hemmer – Evaluierung von Untersuchungsergebnissen in biologischem Material

Simone Schmitz-Spanke, Hans Drexler, Andrea Hartwig &

Glycidol – Evaluation of a BAR

Thomas Göen, Hans Drexler, Andrea Hartwig &

2-Naphthylamine – Addendum for re-evaluation of study results in biological material

Klaus Golka, Hans Drexler, Andrea Hartwig &

Manganese – Determination of manganese and its inorganic compounds in workplace air using atomic absorption spectrometry (AAS)

Claudia Schuh, Michael Kirchner, Ralph Hebisch, Thomas Helmut Brock, Andrea Hartwig &

Xylol (alle Isomere)

Andrea Hartwig &

Registration Year

  • 2021
    158

Resource Types

  • Text
    108
  • Journal Article
    49
  • Other
    1

Affiliations

  • Jena University Hospital
    3
  • University Hospital in Halle
    3
  • Hospital Universitario 12 De Octubre
    2
  • Technical University of Munich
    2
  • Ospedale Santa Chiara
    1
  • Oslo University Hospital
    1
  • Witten/Herdecke University
    1
  • University Hospital Heidelberg
    1
  • Heinrich Heine University Düsseldorf
    1
  • Essen University Hospital
    1