158 Works

Selenium and its inorganic compounds – Addendum for evaluation of BAR

Annette Greiner, Hans Drexler, Andrea Hartwig &
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated biological reference values (BAR) for selenium [7782-49-2] in plasma and in urine to characterise the internal exposure. Selenium is an essential trace element, which is incorporated in considerable amounts by nutrition. Occupational exposure can lead to an additional selenium uptake. Its metabolism and distribution behaviour are complex. In plasma most selenium is bound to proteins and demonstrates...

Humanbiomonitoring nach akuter Exposition und unfallartigen Ereignissen

Thomas Jäger, Michael Bader, Thomas Göen, Hans Drexler, Andrea Hartwig &
Human biomonitoring (HBM) is a well-established tool in occupational medicine, particularly for the prevention of health effects after chronic exposure. However, there are also exceptional short-term exposures or accident-related events which require a toxicological risk assessment. The German Permanent Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area deliberated and summarised basic information and recommendations on human biomonitoring after acute exposure. The design and implementation of sampling procedures, e. g....

Trichloroacetic acid and sodium trichloroacetate

Andrea Hartwig &
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated trichloroacetic acid [76-03-9] and sodium trichloroacetate [650-51-1] to derive a maximum concentration at the workplace (MAK value), considering all toxicity endpoints. Available publications are described in detail. After oral application of trichloroacetic acid or the sodium salt, the target organ is the liver with mice being more susceptible than rats. Trichloroacetic acid can be regarded as non-genotoxic....

Peroxyessigsäure

Andrea Hartwig &
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated peracetic acid [79-21-0] considering all toxicological end points. Peracetic acid is commercially available only in aqueous solutions, in which it exists in equilibrium with hydrogen peroxide and acetic acid. Therefore, all three substances contribute to toxicity. No specific systemic effects were observed, which is plausible because peracetic acid immediately oxidizes the tissues at the point of contact...

Geraniol – Determination of 8‑carboxy­geraniol, Hildebrandt acid, geranic acid, and 3‑hydroxycitronellic acid in urine by UPLC‑MS/MS

Thomas Jäger, Sandra Bäcker, Thomas Brodbeck, Michael Bader, Gerhard Scherer, Markus Stöckelhuber, Thomas Göen, Andrea Hartwig &
The working group “Analyses in Biological Materials” of the Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area developed and verified the presented biomonitoring method.The method described herein enables the selective and quantitative determination of geraniol metabolites in human urine into the concentration range relevant for environmental exposure. The following four metabolites can be determined using this method: 8‑carboxygeraniol, Hildebrandt acid, geranic acid, and 3‑hydroxycitronellic acid. Hildebrandt acid,...

2-Butanthiol

Andrea Hartwig &
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated data for 2-butanethiol [513-53-1] considering all toxicological end points. Data from a 90-day inhalation study with rats show that the critical effects are haematotoxicity and histopathological alterations in the nasal olfactory epithelium. On the basis of the NOAEC of 25 ml/m for systemic toxicity and taking into account the increased respiratory volume at the workplace, the maximum...

4,4′-Methylenebis(2-chloroaniline) (MOCA) – Evaluation of a BAR

Pia Lämmlein

Tetramethyllead

Andrea Hartwig &

2-Butanone – Addendum for re-evaluation of the BAT value

Michael Nasterlack

Acrylnitril – Addendum zur Reevaluierung von EKA und BAR

Thomas Jäger, Hans Drexler, Andrea Hartwig &

5.3.5. Systemische Therapie

Christina Hunger-Schoppe & Jochen Schweitzer-Rothers

Indium – Bestimmung von Indium und seinen Verbindungen in der Luft am Arbeitsplatz mittels Massenspektrometrie mit induktiv gekoppeltem Plasma (ICP-MS)

Katrin Pitzke, Kurt Timm, Ralph Hebisch, Andrea Hartwig &

Di-n-butyl phosphate and its technical mixtures

Andrea Hartwig &

7‑Hydroxycitronellal – Determination of 7‑hydroxycitronellylic acid in urine by UPLC‑MS/MS

Markus Stöckelhuber, Gerhard Scherer, Thomas Jäger, Thomas Göen, Andrea Hartwig &

4-Methyl-3-penten-2-one

Andrea Hartwig &

N-Butyl-1,2-benzisothiazolin-3-on

Andrea Hartwig &

Änderung der Einstufung krebserzeugender Arbeitsstoffe

Andrea Hartwig &

5.3.4. Gesprächspsychotherapie als Beispiel für eine Methode der Humanistischen Therapie

Stefan Watzke
Kapitel des Online Lehrbuch der Medizinischen Psychologie und Medizinischen Soziologie

5.4.1. Psychotherapeutische und psychologische Tätigkeitsfelder in der Medizin: ein Überblick

Bernhard Strauß
Kapitel des Online Lehrbuch der Medizinischen Psychologie und Medizinischen Soziologie

5.3.2. Psychodynamische Psychotherapie

Bernhard Strauß
Kapitel des Online Lehrbuch der Medizinischen Psychologie und Medizinischen Soziologie

5.4. Typische Tätigkeitsfelder für psychologische Interventionen und Psychotherapie in der Medizin

Bernhard Strauß
Kapitel des Online Lehrbuch der Medizinischen Psychologie und Medizinischen Soziologie

1,2-Dichlorpropan – Evaluierung von Untersuchungsergebnissen in biologischem Material

Elisabeth Eckert, Hans Drexler, Andrea Hartwig &

Indium – Determination of indium and its compounds in workplace air using mass spectrometry with inductively coupled plasma (ICP-MS)

Katrin Pitzke, Kurt Timm, Ralph Hebisch, Thomas Helmut Brock, Andrea Hartwig &

Lista de valores MAK y BAT 2021

Carbon monoxide – Addendum for re-evaluation of the BAT value

Britta Brinkmann, Rüdiger Bartsch, Christoph van Thriel, Hans Drexler, Andrea Hartwig &
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated the biological tolerance value (BAT value) of carbon monoxide (CO) [630-08-0]. Exercising healthy test persons became statistically significantly faster exhausted at CO exposures resulting in a CO-Hb content of 3.35 to 5.1%. This was only observed with very high physical activity (minute volume of 100 l/min) which is much higher than that assumed to be realistic in...

Registration Year

  • 2021
    158

Resource Types

  • Text
    108
  • Journal Article
    49
  • Other
    1

Affiliations

  • Jena University Hospital
    3
  • University Hospital in Halle
    3
  • Hospital Universitario 12 De Octubre
    2
  • Technical University of Munich
    2
  • Ospedale Santa Chiara
    1
  • Oslo University Hospital
    1
  • Witten/Herdecke University
    1
  • University Hospital Heidelberg
    1
  • Heinrich Heine University Düsseldorf
    1
  • Essen University Hospital
    1