11,623,267 Works

Proposed O-GalNAc/Gal glycosylation pathways during Plasmodium falciparum infections in blood group O and non-O blood groups

Peter Arend
After controversial discussions about N- and O-glycosylations, performed by the protozoan parasite Plasmodium falciparum, this parasite obviously lacks normal GalNAc syntheses when compared with metazoan species and apparently needs connection to metazoan O-GalNAc glycosylations, while infections occur regardless of the human ABO blood groups. After entry into a metazoan host (flies or vertebrates), the parasite's serine residues are exposed to glycotransferase activities, expressed by plasma proteins and surfaces of mononuclear cells. In human blood group...

GBIF Occurrence Download

Occdownload Gbif.Org
A dataset containing 94 species occurrences available in GBIF matching the query: Country: Spain Geometry: POLYGON((0.57034 42.72816,0.42581 42.27705,0.30822 40.69626,0.47138 40.45798,1.31089 40.38022,3.60077 40.80913,3.49571 42.43771,2.86906 42.58342,2.59698 42.41319,2.41536 42.59164,2.02457 42.55833,0.79278 42.94665,0.57034 42.72816)) TaxonKey: Procambarus clarkii (Girard, 1852) HasGeospatialIssue: false. The dataset includes 94 records from 5 constituent datasets: 3 records from iNaturalist Research-grade Observations. 85 records from Data collected on scitizen science web portal www.ornitho.cat. 4 records from Efectos del Cambio Ambiental en las comunidades de organismos de...

Ciência 2017

Francisco Rego, A. Pedro Aguiar, Colin Jones & Antonio Pascoal

Intensive Motivational Interviewing for Heavy Drinking among Women

D Polcin, R A Korcha, M Salinardi, M Nayak, G Galloway & S Pugh

Acclimate V3.0.0

Sven Willner & Christian Otto
Acclimate - Model for economic loss propagation

Closed Doors Everywhere? A Meta-Analysis of Field Experiments on Ethnic Discrimination in Rental Housing Markets

Katrin.Auspurg@Lmu.De, Andreas Schneck & Thomas.Hinz@Uni-Konstanz.De
Discrimination is long seen as a meaningful factor for ethnic inequalities on rental housing markets. Yet empirically, the extent of discrimination is still debatable. For the first time, this article provides a quantitative meta-analysis of 71 experimental studies (in person audits and correspondence tests) that were run over the last four decades in the United States, Canada and Europe. Special focus is given to a possible inflation of effect sizes by publication bias; to time...

Determination of Inner and Outer Bounds of Reachable Sets

Francisco Rego, Eddy Van Oort, Q. P. Chu, Erik-Jan Van Kampen & Antonio Pascoal

Hyaluronic acid/doxorubicin nanoassembly-releasing microspheres for the transarterial chemoembolization of a liver tumor

Song Yi Lee, Jin Woo Choi, Jae-Young Lee, Dae-Duk Kim, Hyo-Cheol Kim & Hyun-Jong Cho
Doxorubicin (DOX)-loaded, hyaluronic acid-ceramide (HACE) nanoassembly-releasing poly(lactic-co-glycolic acid) (PLGA) microspheres (MSs) were developed for transarterial chemoembolization (TACE) therapy of liver cancer. DOX/HACE MSs with a mean diameter of 27 μm and a spherical shape were prepared based on the modified emulsification method. Their in vitro biodegradability in artificial biological fluids was observed. A more sustained drug release pattern was observed from DOX/HACE MS than from DOX MS at pH 7.4. The cellular internalization efficiency of DOX...

Hyaluronic acid/doxorubicin nanoassembly-releasing microspheres for the transarterial chemoembolization of a liver tumor

Song Yi Lee, Jin Woo Choi, Jae-Young Lee, Dae-Duk Kim, Hyo-Cheol Kim & Hyun-Jong Cho
Doxorubicin (DOX)-loaded, hyaluronic acid-ceramide (HACE) nanoassembly-releasing poly(lactic-co-glycolic acid) (PLGA) microspheres (MSs) were developed for transarterial chemoembolization (TACE) therapy of liver cancer. DOX/HACE MSs with a mean diameter of 27 μm and a spherical shape were prepared based on the modified emulsification method. Their in vitro biodegradability in artificial biological fluids was observed. A more sustained drug release pattern was observed from DOX/HACE MS than from DOX MS at pH 7.4. The cellular internalization efficiency of DOX...

Identifying Spammers in Social Media Marketing

Arpan Kumar Kar & P Vigneswara Ilavarasan

Dissolution: A Predictive Tool For Conventional And Novel Dosage Forms

ABSTRACT Dissolution is an official test used by pharmacopeias for evaluating drug release of solid and semisolid dosage forms. The main applications of the dissolution testing include biopharmaceutical characterization of the drug product, as a tool to ensure consistent product quality and to predict in vivo drug bioavailability. Dissolution testing was developed initially for solid orals, later on its use is widened to a variety of novel dosage forms. Due to the complexities in the...

Dissolution: A Predictive Tool For Conventional And Novel Dosage Forms

ABSTRACT Dissolution is an official test used by pharmacopeias for evaluating drug release of solid and semisolid dosage forms. The main applications of the dissolution testing include biopharmaceutical characterization of the drug product, as a tool to ensure consistent product quality and to predict in vivo drug bioavailability. Dissolution testing was developed initially for solid orals, later on its use is widened to a variety of novel dosage forms. Due to the complexities in the...

GBIF Occurrence Download

Occdownload Gbif.Org
A dataset containing 8 species occurrences available in GBIF matching the query: DatasetKey: (Table 1) Proportion of Toxoplasma gondii seropositive arctic foxes (Alopex lagopus) by age group and geographic area. The dataset includes 8 records from 1 constituent datasets: 8 records from (Table 1) Proportion of Toxoplasma gondii seropositive arctic foxes (Alopex lagopus) by age group and geographic area. Data from some individual datasets included in this download may be licensed under less restrictive terms.

Formulation And Evaluation Of Floating And Mucoadhesive Tablet Of Oral Hypoglycemic Drug Of Nateglinide

ABSTRACT In the present research work gastro retentive mucoadhesive floating formulation of Nateglinide by using various hydrophilic polymers. Nateglinide is a drug for the treatment of type 2 diabetes. Initially analytical method development was done for the drug molecule (1-4). Absorption maxima was determined based on that calibration curve was developed by using different concentrations. Gas generating agent accrual and bioadhesive polymer carbopol concentration was optimized. Twelve formulations were developed by using different concentrations of polymers of various polymers....

Formulation And Evaluation Of Floating And Mucoadhesive Tablet Of Oral Hypoglycemic Drug Of Nateglinide

ABSTRACT In the present research work gastro retentive mucoadhesive floating formulation of Nateglinide by using various hydrophilic polymers. Nateglinide is a drug for the treatment of type 2 diabetes. Initially analytical method development was done for the drug molecule (1-4). Absorption maxima was determined based on that calibration curve was developed by using different concentrations. Gas generating agent accrual and bioadhesive polymer carbopol concentration was optimized. Twelve formulations were developed by using different concentrations of polymers of various polymers....

Nhejazi/Biotmle: Biotmle: Bioc 3.7

Nima Hejazi, Hpages, Vobencha & Martin Morgan
:package: :microscope: R/biotmle: Model-free biomarker discovery using moderated statistics and Targeted Learning

Formulation And Evaluation Of Floating And Mucoadhesive Tablet Of Oral Hypoglycemic Drug Of Metformin

ABSTRACT In the present research work gastro retentive mucoadhesive floating formulation of Metformin by using various hydrophilic polymers. Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.  Initially analytical method development was done for the drug molecule. KEYWORDS: Metformin, Hydrophilic polymers, Floating and Mucoadhesive tablet.

Formulation And Evaluation Of Floating And Mucoadhesive Tablet Of Oral Hypoglycemic Drug Of Metformin

ABSTRACT In the present research work gastro retentive mucoadhesive floating formulation of Metformin by using various hydrophilic polymers. Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.  Initially analytical method development was done for the drug molecule. KEYWORDS: Metformin, Hydrophilic polymers, Floating and Mucoadhesive tablet.

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